{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Silicone+Hydrogel+Contact+Lenses&page=4",
    "query": {
      "intervention": "Silicone Hydrogel Contact Lenses",
      "page": 4
    },
    "page_size": 10
  },
  "pagination": {
    "page": 4,
    "page_size": 10,
    "total_count": 136,
    "total_pages": 14,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Silicone+Hydrogel+Contact+Lenses&page=5&page_size=10",
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Silicone+Hydrogel+Contact+Lenses&page=3&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-10-10T13:24:01.905Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT01476722",
      "title": "Lens Wearing Experience and Biocompatibility of a Multi-Purpose Disinfecting Solution (MPDS)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Healthy"
      ],
      "interventions": [
        {
          "name": "OPTI-FREE PureMoist multipurpose disinfecting solution",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Alcon Research",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 125,
      "start_date": "2011-06",
      "completion_date": "2011-10",
      "has_results": true,
      "last_update_posted_date": "2012-11-19",
      "last_synced_at": "2026-10-10T13:24:01.905Z",
      "location_count": 1,
      "location_summary": "Fort Worth, Texas",
      "locations": [
        {
          "city": "Fort Worth",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01476722"
    },
    {
      "nct_id": "NCT05211739",
      "title": "Clinical Assessment of a Daily Wear Monthly Replacement Silicone Hydrogel Toric Contact Lens",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Refractive Errors",
        "Astigmatism"
      ],
      "interventions": [
        {
          "name": "Lehfilcon A toric contact lenses",
          "type": "DEVICE"
        },
        {
          "name": "Comfilcon A toric contact lenses",
          "type": "DEVICE"
        },
        {
          "name": "CLEAR CARE",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Alcon Research",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 76,
      "start_date": "2022-02-15",
      "completion_date": "2022-06-23",
      "has_results": true,
      "last_update_posted_date": "2023-06-27",
      "last_synced_at": "2026-10-10T13:24:01.905Z",
      "location_count": 7,
      "location_summary": "Longwood, Florida • Maitland, Florida • Orlando, Florida + 4 more",
      "locations": [
        {
          "city": "Longwood",
          "state": "Florida"
        },
        {
          "city": "Maitland",
          "state": "Florida"
        },
        {
          "city": "Orlando",
          "state": "Florida"
        },
        {
          "city": "Pittsburg",
          "state": "Kansas"
        },
        {
          "city": "Willmar",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05211739"
    },
    {
      "nct_id": "NCT03459131",
      "title": "Clinical Evaluation of Two Monthly Contact Lenses",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Refractive Errors"
      ],
      "interventions": [
        {
          "name": "Comfilcon A with Digital Zone Optics™ contact lenses",
          "type": "DEVICE"
        },
        {
          "name": "Comfilcon A contact lenses",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Alcon Research",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "35 Years",
        "sex": "ALL",
        "summary": "18 Years to 35 Years"
      },
      "enrollment_count": 15,
      "start_date": "2018-03-07",
      "completion_date": "2018-03-26",
      "has_results": true,
      "last_update_posted_date": "2019-03-05",
      "last_synced_at": "2026-10-10T13:24:01.905Z",
      "location_count": 1,
      "location_summary": "Maitland, Florida",
      "locations": [
        {
          "city": "Maitland",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03459131"
    },
    {
      "nct_id": "NCT00804505",
      "title": "Hybrid SA RGP Center/S-H Skirt Daily Wear 90 Day Multicenter Study",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Corneal Disease",
        "Hypersensitivity"
      ],
      "interventions": [
        {
          "name": "SynergEyes Hybrid (petrafocon A hem-larafilcon A) Hybrid Contact Lens",
          "type": "DEVICE"
        },
        {
          "name": "SynergEyes Hybrid (paflufocon D hem-iberfilcon A) Contact Lens",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "SynergEyes, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 98,
      "start_date": "2008-06",
      "completion_date": "2008-12",
      "has_results": false,
      "last_update_posted_date": "2009-12-23",
      "last_synced_at": "2026-10-10T13:24:01.905Z",
      "location_count": 8,
      "location_summary": "San Diego, California • Sunnyvale, California • Andover, Massachusetts + 5 more",
      "locations": [
        {
          "city": "San Diego",
          "state": "California"
        },
        {
          "city": "Sunnyvale",
          "state": "California"
        },
        {
          "city": "Andover",
          "state": "Massachusetts"
        },
        {
          "city": "East Lansing",
          "state": "Michigan"
        },
        {
          "city": "Beachwood",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00804505"
    },
    {
      "nct_id": "NCT04093258",
      "title": "Comparison of Two Silicone Hydrogel Multifocal Contact Lenses",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Visual Acuity"
      ],
      "interventions": [
        {
          "name": "Dailies Total 1® Multifocal Contact Lenses",
          "type": "DEVICE"
        },
        {
          "name": "Air Optix® Multifocal Contact Lenses Plus HydraGlyde®",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Johnson & Johnson Vision Care, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "40 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "40 Years to 70 Years"
      },
      "enrollment_count": 42,
      "start_date": "2019-08-26",
      "completion_date": "2019-12-11",
      "has_results": true,
      "last_update_posted_date": "2021-12-01",
      "last_synced_at": "2026-10-10T13:24:01.905Z",
      "location_count": 3,
      "location_summary": "Roswell, Georgia • Granville, Ohio • Memphis, Tennessee",
      "locations": [
        {
          "city": "Roswell",
          "state": "Georgia"
        },
        {
          "city": "Granville",
          "state": "Ohio"
        },
        {
          "city": "Memphis",
          "state": "Tennessee"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04093258"
    },
    {
      "nct_id": "NCT01706770",
      "title": "Evaluation of Enfilcon A Soft Contact Lens When Compared to Galyfilcon A Soft Contact Lens",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Ametropia"
      ],
      "interventions": [
        {
          "name": "enfilcon A",
          "type": "DEVICE"
        },
        {
          "name": "galyfilcon A",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "CooperVision, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 50,
      "start_date": "2012-05",
      "completion_date": "2012-10",
      "has_results": true,
      "last_update_posted_date": "2020-10-05",
      "last_synced_at": "2026-10-10T13:24:01.905Z",
      "location_count": 3,
      "location_summary": "Pismo Beach, California • San Diego, California • East Lansing, Michigan",
      "locations": [
        {
          "city": "Pismo Beach",
          "state": "California"
        },
        {
          "city": "San Diego",
          "state": "California"
        },
        {
          "city": "East Lansing",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01706770"
    },
    {
      "nct_id": "NCT00987623",
      "title": "Clinical Evaluation of Two Daily Disposable Lenses in Neophytes",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Myopia"
      ],
      "interventions": [
        {
          "name": "nelfilcon A contact lens",
          "type": "DEVICE"
        },
        {
          "name": "narafilcon A contact lens",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "CIBA VISION",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "45 Years",
        "sex": "ALL",
        "summary": "Up to 45 Years"
      },
      "enrollment_count": 326,
      "start_date": "2009-08",
      "completion_date": "2009-12",
      "has_results": true,
      "last_update_posted_date": "2012-07-10",
      "last_synced_at": "2026-10-10T13:24:01.905Z",
      "location_count": 1,
      "location_summary": "Fort Washington, Pennsylvania",
      "locations": [
        {
          "city": "Fort Washington",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00987623"
    },
    {
      "nct_id": "NCT01484938",
      "title": "Lens Wearing Experience and Biocompatibility of a Marketed Multi-Purpose Disinfecting Solution in Silicone Hydrogel and Soft Contact Lens Wearers",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Refractive Error"
      ],
      "interventions": [
        {
          "name": "OPTI-FREE PureMoist",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Alcon Research",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 175,
      "start_date": "2011-02",
      "completion_date": "2011-05",
      "has_results": true,
      "last_update_posted_date": "2012-10-10",
      "last_synced_at": "2026-10-10T13:24:01.905Z",
      "location_count": 1,
      "location_summary": "Fort Worth, Texas",
      "locations": [
        {
          "city": "Fort Worth",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01484938"
    },
    {
      "nct_id": "NCT04050618",
      "title": "Evaluation Of One Silicone Hydrogel Contact Lens and Two Hydrogel Lenses in Daily Wear",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Myopia"
      ],
      "interventions": [
        {
          "name": "fanfilcon A test lens",
          "type": "DEVICE"
        },
        {
          "name": "ocufilcon D control lens",
          "type": "DEVICE"
        },
        {
          "name": "etafilcon A control lens",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "CooperVision, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 114,
      "start_date": "2019-06-09",
      "completion_date": "2019-11-08",
      "has_results": true,
      "last_update_posted_date": "2020-10-19",
      "last_synced_at": "2026-10-10T13:24:01.905Z",
      "location_count": 6,
      "location_summary": "Whittier, California • Longwood, Florida • Sarasota, Florida + 3 more",
      "locations": [
        {
          "city": "Whittier",
          "state": "California"
        },
        {
          "city": "Longwood",
          "state": "Florida"
        },
        {
          "city": "Sarasota",
          "state": "Florida"
        },
        {
          "city": "Vestal",
          "state": "New York"
        },
        {
          "city": "Tyler",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04050618"
    },
    {
      "nct_id": "NCT06469242",
      "title": "Clinical Performance of Two Frequent Replacement Silicone Hydrogel Multifocal Contact Lenses",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Presbyopia"
      ],
      "interventions": [
        {
          "name": "Serafilcon A multifocal contact lenses",
          "type": "DEVICE"
        },
        {
          "name": "Senofilcon A multifocal contact lenses",
          "type": "DEVICE"
        },
        {
          "name": "CLEAR CARE® Cleaning & Disinfecting Solution",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Alcon Research",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "40 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "40 Years and older"
      },
      "enrollment_count": 106,
      "start_date": "2024-07-18",
      "completion_date": "2024-10-08",
      "has_results": true,
      "last_update_posted_date": "2025-10-09",
      "last_synced_at": "2026-10-10T13:24:01.905Z",
      "location_count": 8,
      "location_summary": "Los Angeles, California • Oakland, California • Maitland, Florida + 5 more",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Oakland",
          "state": "California"
        },
        {
          "city": "Maitland",
          "state": "Florida"
        },
        {
          "city": "Orlando",
          "state": "Florida"
        },
        {
          "city": "Medina",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06469242"
    }
  ]
}