{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Silicone+Hydrogel+Soft+Contact+Lenses",
    "query": {
      "intervention": "Silicone Hydrogel Soft Contact Lenses"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 58,
    "total_pages": 6,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Silicone+Hydrogel+Soft+Contact+Lenses&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-10-06T02:17:59.371Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT04189224",
      "title": "Evaluation of a Reusable Silicone Hydrogel Multifocal Contact Lens",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Presbyopia"
      ],
      "interventions": [
        {
          "name": "JJV Investigational Multifocal Contact Lens",
          "type": "DEVICE"
        },
        {
          "name": "1-Day Acuvue® Moist Brand Multifocal Contact Lens",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Johnson & Johnson Vision Care, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "40 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "40 Years to 70 Years"
      },
      "enrollment_count": 46,
      "start_date": "2019-11-15",
      "completion_date": "2020-03-10",
      "has_results": true,
      "last_update_posted_date": "2025-04-27",
      "last_synced_at": "2026-10-06T02:17:59.371Z",
      "location_count": 4,
      "location_summary": "Maitland, Florida • Raytown, Missouri • Granville, Ohio + 1 more",
      "locations": [
        {
          "city": "Maitland",
          "state": "Florida"
        },
        {
          "city": "Raytown",
          "state": "Missouri"
        },
        {
          "city": "Granville",
          "state": "Ohio"
        },
        {
          "city": "Jacksonville",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04189224"
    },
    {
      "nct_id": "NCT04532099",
      "title": "Clinical Comparison of Two Daily Wear Frequent Replacement Silicone Hydrogel Soft Contact Lenses",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Refractive Errors",
        "Ametropia"
      ],
      "interventions": [
        {
          "name": "Lehfilcon A contact lenses",
          "type": "DEVICE"
        },
        {
          "name": "Senofilcon A contact lenses",
          "type": "DEVICE"
        },
        {
          "name": "Comfilcon A contact lenses",
          "type": "DEVICE"
        },
        {
          "name": "Hydrogen peroxide-based cleaning and disinfecting solution",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Alcon Research",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 132,
      "start_date": "2020-09-09",
      "completion_date": "2021-05-04",
      "has_results": true,
      "last_update_posted_date": "2022-05-03",
      "last_synced_at": "2026-10-06T02:17:59.371Z",
      "location_count": 4,
      "location_summary": "Longwood, Florida • Maitland, Florida • Warwick, Rhode Island + 1 more",
      "locations": [
        {
          "city": "Longwood",
          "state": "Florida"
        },
        {
          "city": "Maitland",
          "state": "Florida"
        },
        {
          "city": "Warwick",
          "state": "Rhode Island"
        },
        {
          "city": "Memphis",
          "state": "Tennessee"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04532099"
    },
    {
      "nct_id": "NCT01211535",
      "title": "Subjective Comfort With Multipurpose Care Solutions in Soft Contact Lens Wearers",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Myopia",
        "Astigmatism",
        "Refractive Error"
      ],
      "interventions": [
        {
          "name": "OPTI-FREE RepleniSH multipurpose solution",
          "type": "DEVICE"
        },
        {
          "name": "ReNu Biotrue multipurpose solution",
          "type": "DEVICE"
        },
        {
          "name": "Silicone hydrogel contact lenses",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Alcon Research",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 104,
      "start_date": "2010-09",
      "completion_date": "2010-11",
      "has_results": true,
      "last_update_posted_date": "2012-11-12",
      "last_synced_at": "2026-10-06T02:17:59.371Z",
      "location_count": 1,
      "location_summary": "Fort Worth, Texas",
      "locations": [
        {
          "city": "Fort Worth",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01211535"
    },
    {
      "nct_id": "NCT05827224",
      "title": "Air Optix Daily Wear Contact Lenses",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Refractive Errors"
      ],
      "interventions": [
        {
          "name": "Lotrafilcon B spherical soft contact lenses",
          "type": "DEVICE"
        },
        {
          "name": "Lotrafilcon B spherical soft contact lenses with comfort additive",
          "type": "DEVICE"
        },
        {
          "name": "Lotrafilcon B toric soft contact lenses with comfort additive",
          "type": "DEVICE"
        },
        {
          "name": "Comfilcon A spherical soft contact lenses",
          "type": "DEVICE"
        },
        {
          "name": "Comfilcon A toric soft contact lenses",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Alcon Research",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": null,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 312,
      "start_date": "2023-08-02",
      "completion_date": "2024-07-17",
      "has_results": false,
      "last_update_posted_date": "2024-08-15",
      "last_synced_at": "2026-10-06T02:17:59.371Z",
      "location_count": 5,
      "location_summary": "Orlando, Florida • Medina, Minnesota • St Louis, Missouri + 2 more",
      "locations": [
        {
          "city": "Orlando",
          "state": "Florida"
        },
        {
          "city": "Medina",
          "state": "Minnesota"
        },
        {
          "city": "St Louis",
          "state": "Missouri"
        },
        {
          "city": "Nashville",
          "state": "Tennessee"
        },
        {
          "city": "Salt Lake City",
          "state": "Utah"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05827224"
    },
    {
      "nct_id": "NCT06592521",
      "title": "OPTI-FREE Family STUDY",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Contact Lens Care"
      ],
      "interventions": [
        {
          "name": "OPTI-FREE EXPRESS MPDS and Alcon contact lens case",
          "type": "DEVICE"
        },
        {
          "name": "OPTI-FREE PureMoist MPDS and Alcon contact lens case",
          "type": "DEVICE"
        },
        {
          "name": "OPTI-FREE REPLENISH MPDS and Alcon contact lens case",
          "type": "DEVICE"
        },
        {
          "name": "Habitual contact lenses",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Alcon Research",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "7 Years",
        "maximum_age": "17 Years",
        "sex": "ALL",
        "summary": "7 Years to 17 Years"
      },
      "enrollment_count": 0,
      "start_date": "2025-10",
      "completion_date": "2026-01",
      "has_results": false,
      "last_update_posted_date": "2025-09-16",
      "last_synced_at": "2026-10-06T02:17:59.371Z",
      "location_count": 1,
      "location_summary": "Fort Worth, Texas",
      "locations": [
        {
          "city": "Fort Worth",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06592521"
    },
    {
      "nct_id": "NCT04085328",
      "title": "Assessment of an Investigational Frequent Replacement Silicone Hydrogel Lens",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Refractive Ametropia"
      ],
      "interventions": [
        {
          "name": "LID015385 soft contact lenses",
          "type": "DEVICE"
        },
        {
          "name": "Comfilcon A soft contact lenses",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Alcon Research",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 675,
      "start_date": "2019-10-11",
      "completion_date": "2021-03-26",
      "has_results": true,
      "last_update_posted_date": "2023-06-13",
      "last_synced_at": "2026-10-06T02:17:59.371Z",
      "location_count": 42,
      "location_summary": "Campbell, California • Fullerton, California • Los Angeles, California + 34 more",
      "locations": [
        {
          "city": "Campbell",
          "state": "California"
        },
        {
          "city": "Fullerton",
          "state": "California"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Oakland",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04085328"
    },
    {
      "nct_id": "NCT04207749",
      "title": "Clinical Evaluation of a Daily Wear Silicone Hydrogel Lens",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Refractive Errors",
        "Myopia",
        "Hyperopia"
      ],
      "interventions": [
        {
          "name": "LID015385 contact lenses",
          "type": "DEVICE"
        },
        {
          "name": "Comfilcon A contact lenses",
          "type": "DEVICE"
        },
        {
          "name": "CLEAR CARE",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Alcon Research",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 249,
      "start_date": "2020-01-22",
      "completion_date": "2020-12-17",
      "has_results": true,
      "last_update_posted_date": "2022-02-02",
      "last_synced_at": "2026-10-06T02:17:59.371Z",
      "location_count": 18,
      "location_summary": "Glendale, Arizona • Brentwood, California • Irvine, California + 15 more",
      "locations": [
        {
          "city": "Glendale",
          "state": "Arizona"
        },
        {
          "city": "Brentwood",
          "state": "California"
        },
        {
          "city": "Irvine",
          "state": "California"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Novato",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04207749"
    },
    {
      "nct_id": "NCT02939950",
      "title": "Silicone Hydrogel Soft Contact Lens 7-Day Extended Wear Basis",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Myopia"
      ],
      "interventions": [
        {
          "name": "Bausch + Lomb Samfilcon A Soft Contact Lens",
          "type": "DEVICE"
        },
        {
          "name": "Bausch + Lomb Pure Vision Soft Contact Lens",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Bausch Health Americas, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "40 Years",
        "sex": "ALL",
        "summary": "18 Years to 40 Years"
      },
      "enrollment_count": 816,
      "start_date": "2015-04-30",
      "completion_date": "2016-08-03",
      "has_results": true,
      "last_update_posted_date": "2019-12-23",
      "last_synced_at": "2026-10-06T02:17:59.371Z",
      "location_count": 1,
      "location_summary": "Cicero, New York",
      "locations": [
        {
          "city": "Cicero",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02939950"
    },
    {
      "nct_id": "NCT01735045",
      "title": "LSH Silicone Hydrogel Soft Hydrophilic Contact Lens for Daily Wear",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Myopia"
      ],
      "interventions": [
        {
          "name": "Lagado LSH (mangofilcon A) Soft (hydrophilic) Contact Lens",
          "type": "DEVICE"
        },
        {
          "name": "Benz 3GX (hioxifilcon B) Soft (hydrophilic) Contact Lens",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Szabocsik and Associates, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 76,
      "start_date": "2010-05",
      "completion_date": "2012-01",
      "has_results": false,
      "last_update_posted_date": "2012-11-28",
      "last_synced_at": "2026-10-06T02:17:59.371Z",
      "location_count": 5,
      "location_summary": "Huntington Beach, California • Honolulu, Hawaii • Oak Lawn, Illinois + 2 more",
      "locations": [
        {
          "city": "Huntington Beach",
          "state": "California"
        },
        {
          "city": "Honolulu",
          "state": "Hawaii"
        },
        {
          "city": "Oak Lawn",
          "state": "Illinois"
        },
        {
          "city": "Concord",
          "state": "New Hampshire"
        },
        {
          "city": "Londonderry",
          "state": "New Hampshire"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01735045"
    },
    {
      "nct_id": "NCT01706770",
      "title": "Evaluation of Enfilcon A Soft Contact Lens When Compared to Galyfilcon A Soft Contact Lens",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Ametropia"
      ],
      "interventions": [
        {
          "name": "enfilcon A",
          "type": "DEVICE"
        },
        {
          "name": "galyfilcon A",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "CooperVision, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 50,
      "start_date": "2012-05",
      "completion_date": "2012-10",
      "has_results": true,
      "last_update_posted_date": "2020-10-05",
      "last_synced_at": "2026-10-06T02:17:59.371Z",
      "location_count": 3,
      "location_summary": "Pismo Beach, California • San Diego, California • East Lansing, Michigan",
      "locations": [
        {
          "city": "Pismo Beach",
          "state": "California"
        },
        {
          "city": "San Diego",
          "state": "California"
        },
        {
          "city": "East Lansing",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01706770"
    }
  ]
}