{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Silicone+hydrogel+contact+lenses",
    "query": {
      "intervention": "Silicone hydrogel contact lenses"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 136,
    "total_pages": 14,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Silicone+hydrogel+contact+lenses&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-10-04T18:29:37.374Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT03614130",
      "title": "Clinical Performance of a Silicone Hydrogel Contact Lens Following Six Nights of Extended Wear",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Refractive Errors"
      ],
      "interventions": [
        {
          "name": "LID011121 contact lens",
          "type": "DEVICE"
        },
        {
          "name": "Comfilcon A contact lens",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Alcon Research",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 22,
      "start_date": "2018-08-23",
      "completion_date": "2018-09-11",
      "has_results": true,
      "last_update_posted_date": "2021-09-30",
      "last_synced_at": "2026-10-04T18:29:37.374Z",
      "location_count": 2,
      "location_summary": "Johns Creek, Georgia • Brentwood, Tennessee",
      "locations": [
        {
          "city": "Johns Creek",
          "state": "Georgia"
        },
        {
          "city": "Brentwood",
          "state": "Tennessee"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03614130"
    },
    {
      "nct_id": "NCT03459131",
      "title": "Clinical Evaluation of Two Monthly Contact Lenses",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Refractive Errors"
      ],
      "interventions": [
        {
          "name": "Comfilcon A with Digital Zone Optics™ contact lenses",
          "type": "DEVICE"
        },
        {
          "name": "Comfilcon A contact lenses",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Alcon Research",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "35 Years",
        "sex": "ALL",
        "summary": "18 Years to 35 Years"
      },
      "enrollment_count": 15,
      "start_date": "2018-03-07",
      "completion_date": "2018-03-26",
      "has_results": true,
      "last_update_posted_date": "2019-03-05",
      "last_synced_at": "2026-10-04T18:29:37.374Z",
      "location_count": 1,
      "location_summary": "Maitland, Florida",
      "locations": [
        {
          "city": "Maitland",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03459131"
    },
    {
      "nct_id": "NCT03392532",
      "title": "Comparison of Two Silicone Hydrogel Toric Contact Lenses",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Astigmatism"
      ],
      "interventions": [
        {
          "name": "Lotrafilcon B toric contact lenses with HYDRAGLYDE",
          "type": "DEVICE"
        },
        {
          "name": "Lotrafilcon B toric contact lenses",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Alcon Research",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 36,
      "start_date": "2018-01-04",
      "completion_date": "2018-01-26",
      "has_results": true,
      "last_update_posted_date": "2019-01-29",
      "last_synced_at": "2026-10-04T18:29:37.374Z",
      "location_count": 1,
      "location_summary": "Johns Creek, Georgia",
      "locations": [
        {
          "city": "Johns Creek",
          "state": "Georgia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03392532"
    },
    {
      "nct_id": "NCT01244893",
      "title": "Study of ACUVUE® ADVANCE® PLUS Contact Lenses.",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Myopia"
      ],
      "interventions": [
        {
          "name": "Acuvue Advance Plus prePQ",
          "type": "DEVICE"
        },
        {
          "name": "Acuvue Advance Plus postPQ",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Johnson & Johnson Vision Care, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "39 Years",
        "sex": "ALL",
        "summary": "18 Years to 39 Years"
      },
      "enrollment_count": 44,
      "start_date": "2010-10",
      "completion_date": null,
      "has_results": true,
      "last_update_posted_date": "2018-06-19",
      "last_synced_at": "2026-10-04T18:29:37.374Z",
      "location_count": 3,
      "location_summary": "Powell, Ohio • Warwick, Rhode Island • Salem, Virginia",
      "locations": [
        {
          "city": "Powell",
          "state": "Ohio"
        },
        {
          "city": "Warwick",
          "state": "Rhode Island"
        },
        {
          "city": "Salem",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01244893"
    },
    {
      "nct_id": "NCT01423773",
      "title": "Ocular Comfort and OCT Observation of Post Lens Clearance and Ocular Tissue Compression",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Ocular Comfort"
      ],
      "interventions": [
        {
          "name": "Lotrafilcon A test contact lens",
          "type": "DEVICE"
        },
        {
          "name": "Lotrafilcon A control contact lens",
          "type": "DEVICE"
        },
        {
          "name": "Ultra-High Resolution Optical Coherence Tomographer (OCT)",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "CIBA VISION",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 20,
      "start_date": "2011-08",
      "completion_date": "2011-12",
      "has_results": true,
      "last_update_posted_date": "2013-06-28",
      "last_synced_at": "2026-10-04T18:29:37.374Z",
      "location_count": 1,
      "location_summary": "Miami, Florida",
      "locations": [
        {
          "city": "Miami",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01423773"
    },
    {
      "nct_id": "NCT01309100",
      "title": "Product Feasibility of a New Silicone Hydrogel Contact Lens",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Myopia"
      ],
      "interventions": [
        {
          "name": "Investigational Lens",
          "type": "DEVICE"
        },
        {
          "name": "Acuvue Oasys Lens",
          "type": "DEVICE"
        },
        {
          "name": "Air Optix Aqua Lens",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Bausch & Lomb Incorporated",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 144,
      "start_date": "2010-11",
      "completion_date": "2011-01",
      "has_results": true,
      "last_update_posted_date": "2014-04-29",
      "last_synced_at": "2026-10-04T18:29:37.374Z",
      "location_count": 1,
      "location_summary": "Rochester, New York",
      "locations": [
        {
          "city": "Rochester",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01309100"
    },
    {
      "nct_id": "NCT06588400",
      "title": "AOSEPT (CLEAR CARE) PLUS Study",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Contact Lens Care"
      ],
      "interventions": [
        {
          "name": "AOSEPT Plus and AOCup lens case",
          "type": "DEVICE"
        },
        {
          "name": "AOSEPT Plus with HydraGlyde and AOCup lens case",
          "type": "DEVICE"
        },
        {
          "name": "Habitual contact lenses",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Alcon Research",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "7 Years",
        "maximum_age": "17 Years",
        "sex": "ALL",
        "summary": "7 Years to 17 Years"
      },
      "enrollment_count": 0,
      "start_date": "2025-10",
      "completion_date": "2026-01",
      "has_results": false,
      "last_update_posted_date": "2025-09-16",
      "last_synced_at": "2026-10-04T18:29:37.374Z",
      "location_count": 1,
      "location_summary": "Fort Worth, Texas",
      "locations": [
        {
          "city": "Fort Worth",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06588400"
    },
    {
      "nct_id": "NCT01094743",
      "title": "Dispensing Evaluation of a Prototype Contact Lens and a Marketed Contact Lens",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Myopia"
      ],
      "interventions": [
        {
          "name": "galyfilcon A prototype lens",
          "type": "DEVICE"
        },
        {
          "name": "lotrafilcon B lens",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Johnson & Johnson Vision Care, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "39 Years",
        "sex": "ALL",
        "summary": "18 Years to 39 Years"
      },
      "enrollment_count": 52,
      "start_date": "2010-02-01",
      "completion_date": "2010-03-01",
      "has_results": true,
      "last_update_posted_date": "2018-06-19",
      "last_synced_at": "2026-10-04T18:29:37.374Z",
      "location_count": 2,
      "location_summary": "Jacksonville, Florida • Salem, Virginia",
      "locations": [
        {
          "city": "Jacksonville",
          "state": "Florida"
        },
        {
          "city": "Salem",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01094743"
    },
    {
      "nct_id": "NCT04189224",
      "title": "Evaluation of a Reusable Silicone Hydrogel Multifocal Contact Lens",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Presbyopia"
      ],
      "interventions": [
        {
          "name": "JJV Investigational Multifocal Contact Lens",
          "type": "DEVICE"
        },
        {
          "name": "1-Day Acuvue® Moist Brand Multifocal Contact Lens",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Johnson & Johnson Vision Care, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "40 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "40 Years to 70 Years"
      },
      "enrollment_count": 46,
      "start_date": "2019-11-15",
      "completion_date": "2020-03-10",
      "has_results": true,
      "last_update_posted_date": "2025-04-27",
      "last_synced_at": "2026-10-04T18:29:37.374Z",
      "location_count": 4,
      "location_summary": "Maitland, Florida • Raytown, Missouri • Granville, Ohio + 1 more",
      "locations": [
        {
          "city": "Maitland",
          "state": "Florida"
        },
        {
          "city": "Raytown",
          "state": "Missouri"
        },
        {
          "city": "Granville",
          "state": "Ohio"
        },
        {
          "city": "Jacksonville",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04189224"
    },
    {
      "nct_id": "NCT04050618",
      "title": "Evaluation Of One Silicone Hydrogel Contact Lens and Two Hydrogel Lenses in Daily Wear",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Myopia"
      ],
      "interventions": [
        {
          "name": "fanfilcon A test lens",
          "type": "DEVICE"
        },
        {
          "name": "ocufilcon D control lens",
          "type": "DEVICE"
        },
        {
          "name": "etafilcon A control lens",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "CooperVision, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 114,
      "start_date": "2019-06-09",
      "completion_date": "2019-11-08",
      "has_results": true,
      "last_update_posted_date": "2020-10-19",
      "last_synced_at": "2026-10-04T18:29:37.374Z",
      "location_count": 6,
      "location_summary": "Whittier, California • Longwood, Florida • Sarasota, Florida + 3 more",
      "locations": [
        {
          "city": "Whittier",
          "state": "California"
        },
        {
          "city": "Longwood",
          "state": "Florida"
        },
        {
          "city": "Sarasota",
          "state": "Florida"
        },
        {
          "city": "Vestal",
          "state": "New York"
        },
        {
          "city": "Tyler",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04050618"
    }
  ]
}