{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Silicone+hydrogel+contact+lenses&page=2",
    "query": {
      "intervention": "Silicone hydrogel contact lenses",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 136,
    "total_pages": 14,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Silicone+hydrogel+contact+lenses&page=3&page_size=10",
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Silicone+hydrogel+contact+lenses&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-10-09T15:37:54.884Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT05992675",
      "title": "Air Optix® Night and Day® Aqua Continuous Wear",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Refractive Errors"
      ],
      "interventions": [
        {
          "name": "Lotrafilcon A contact lenses",
          "type": "DEVICE"
        },
        {
          "name": "Balafilcon A contact lenses",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Alcon Research",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 1256,
      "start_date": "2023-10-05",
      "completion_date": "2024-08-22",
      "has_results": false,
      "last_update_posted_date": "2024-09-19",
      "last_synced_at": "2026-10-09T15:37:54.884Z",
      "location_count": 8,
      "location_summary": "San Diego, California • Jacksonville, Florida • Miami, Florida + 5 more",
      "locations": [
        {
          "city": "San Diego",
          "state": "California"
        },
        {
          "city": "Jacksonville",
          "state": "Florida"
        },
        {
          "city": "Miami",
          "state": "Florida"
        },
        {
          "city": "Orlando",
          "state": "Florida"
        },
        {
          "city": "Medina",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05992675"
    },
    {
      "nct_id": "NCT04422990",
      "title": "Clinical Evaluation of a Silicone Hydrogel Daily Wear Monthly Replacement Contact Lens",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Refractive Errors"
      ],
      "interventions": [
        {
          "name": "Lehfilcon A contact lenses",
          "type": "DEVICE"
        },
        {
          "name": "Comfilcon A contact lenses",
          "type": "DEVICE"
        },
        {
          "name": "CLEAR CARE",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Alcon Research",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 158,
      "start_date": "2020-10-01",
      "completion_date": "2021-05-18",
      "has_results": true,
      "last_update_posted_date": "2022-03-29",
      "last_synced_at": "2026-10-09T15:37:54.884Z",
      "location_count": 14,
      "location_summary": "Los Angeles, California • Novato, California • Oakland, California + 10 more",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Novato",
          "state": "California"
        },
        {
          "city": "Oakland",
          "state": "California"
        },
        {
          "city": "Oakland",
          "state": "California"
        },
        {
          "city": "San Francisco",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04422990"
    },
    {
      "nct_id": "NCT05891106",
      "title": "AONDA Therapeutic Indication Study I",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Bullous Keratopathy",
        "Corneal Erosion",
        "Entropion",
        "Corneal Edema",
        "Corneal Dystrophy",
        "Corneal Ulcer",
        "Foreign Body in Cornea",
        "Bell Palsy",
        "Keratoconjunctivitis",
        "Filamentary Keratitis",
        "Sicca Syndrome; Keratoconjunctivitis (Etiology)"
      ],
      "interventions": [
        {
          "name": "Lotrafilcon A contact lenses",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Alcon Research",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 55,
      "start_date": "2023-06-28",
      "completion_date": "2023-07-10",
      "has_results": false,
      "last_update_posted_date": "2023-07-20",
      "last_synced_at": "2026-10-09T15:37:54.884Z",
      "location_count": 3,
      "location_summary": "Orlando, Florida • Franklin Park, Illinois • Memphis, Tennessee",
      "locations": [
        {
          "city": "Orlando",
          "state": "Florida"
        },
        {
          "city": "Franklin Park",
          "state": "Illinois"
        },
        {
          "city": "Memphis",
          "state": "Tennessee"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05891106"
    },
    {
      "nct_id": "NCT01309100",
      "title": "Product Feasibility of a New Silicone Hydrogel Contact Lens",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Myopia"
      ],
      "interventions": [
        {
          "name": "Investigational Lens",
          "type": "DEVICE"
        },
        {
          "name": "Acuvue Oasys Lens",
          "type": "DEVICE"
        },
        {
          "name": "Air Optix Aqua Lens",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Bausch & Lomb Incorporated",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 144,
      "start_date": "2010-11",
      "completion_date": "2011-01",
      "has_results": true,
      "last_update_posted_date": "2014-04-29",
      "last_synced_at": "2026-10-09T15:37:54.884Z",
      "location_count": 1,
      "location_summary": "Rochester, New York",
      "locations": [
        {
          "city": "Rochester",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01309100"
    },
    {
      "nct_id": "NCT01151371",
      "title": "Clinical Evaluation Of Two Daily Disposable Contact Lenses And A Monthly Replacement Lens",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Myopia"
      ],
      "interventions": [
        {
          "name": "narafilcon B contact lens",
          "type": "DEVICE"
        },
        {
          "name": "nelfilcon A contact lens",
          "type": "DEVICE"
        },
        {
          "name": "lotrafilcon B contact lens",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Johnson & Johnson Vision Care, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "39 Years",
        "sex": "ALL",
        "summary": "18 Years to 39 Years"
      },
      "enrollment_count": 452,
      "start_date": "2010-02-01",
      "completion_date": "2010-04-01",
      "has_results": true,
      "last_update_posted_date": "2018-06-19",
      "last_synced_at": "2026-10-09T15:37:54.884Z",
      "location_count": 28,
      "location_summary": "Brea, California • Canoga Park, California • Corona, California + 23 more",
      "locations": [
        {
          "city": "Brea",
          "state": "California"
        },
        {
          "city": "Canoga Park",
          "state": "California"
        },
        {
          "city": "Corona",
          "state": "California"
        },
        {
          "city": "Bridgeport",
          "state": "Connecticut"
        },
        {
          "city": "Jacksonville",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01151371"
    },
    {
      "nct_id": "NCT01309906",
      "title": "Evaluation of the Feasibility a New Silicone Hydrogel Contact Lens",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Myopia"
      ],
      "interventions": [
        {
          "name": "Investigational lens",
          "type": "DEVICE"
        },
        {
          "name": "Air Optix Aqua lens",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Bausch & Lomb Incorporated",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 66,
      "start_date": "2010-12",
      "completion_date": "2011-02",
      "has_results": true,
      "last_update_posted_date": "2020-10-22",
      "last_synced_at": "2026-10-09T15:37:54.884Z",
      "location_count": 1,
      "location_summary": "Rochester, New York",
      "locations": [
        {
          "city": "Rochester",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01309906"
    },
    {
      "nct_id": "NCT04942925",
      "title": "Clinical Comparison of Two Daily Disposable Contact Lenses - Pilot Study 3",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Myopia",
        "Ametropia"
      ],
      "interventions": [
        {
          "name": "Verofilcon A contact lenses",
          "type": "DEVICE"
        },
        {
          "name": "Kalifilcon A contact lenses",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Alcon Research",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 60,
      "start_date": "2021-07-20",
      "completion_date": "2021-09-09",
      "has_results": true,
      "last_update_posted_date": "2022-09-07",
      "last_synced_at": "2026-10-09T15:37:54.884Z",
      "location_count": 4,
      "location_summary": "Maitland, Florida • Orlando, Florida • Eden Prairie, Minnesota + 1 more",
      "locations": [
        {
          "city": "Maitland",
          "state": "Florida"
        },
        {
          "city": "Orlando",
          "state": "Florida"
        },
        {
          "city": "Eden Prairie",
          "state": "Minnesota"
        },
        {
          "city": "Powell",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04942925"
    },
    {
      "nct_id": "NCT06483113",
      "title": "DAILIES TOTAL1® Soft Contact Lenses - Post-Market Clinical Follow-up Study",
      "overall_status": "TERMINATED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Myopia",
        "Hyperopia",
        "Presbyopia",
        "Astigmatism"
      ],
      "interventions": [
        {
          "name": "Delefilcon A spherical soft contact lenses",
          "type": "DEVICE"
        },
        {
          "name": "Delefilcon A toric soft contact lenses",
          "type": "DEVICE"
        },
        {
          "name": "Delefilcon A multifocal soft contact lenses",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Alcon Research",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "7 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "7 Years and older"
      },
      "enrollment_count": 192,
      "start_date": "2024-11-26",
      "completion_date": "2025-02-27",
      "has_results": false,
      "last_update_posted_date": "2025-07-20",
      "last_synced_at": "2026-10-09T15:37:54.884Z",
      "location_count": 12,
      "location_summary": "San Diego, California • Ponte Vedra Beach, Florida • West Palm Beach, Florida + 8 more",
      "locations": [
        {
          "city": "San Diego",
          "state": "California"
        },
        {
          "city": "San Diego",
          "state": "California"
        },
        {
          "city": "Ponte Vedra Beach",
          "state": "Florida"
        },
        {
          "city": "West Palm Beach",
          "state": "Florida"
        },
        {
          "city": "Eden Prairie",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06483113"
    },
    {
      "nct_id": "NCT06462456",
      "title": "Post-market Clinical Follow-up Study of Alcon PRECISION1™ Spherical and PRECISION1™ for Astigmatism Soft Contact Lenses",
      "overall_status": "TERMINATED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Refractive Errors"
      ],
      "interventions": [
        {
          "name": "Verofilcon A spherical soft contact lenses",
          "type": "DEVICE"
        },
        {
          "name": "Verofilcon A toric soft contact lenses",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Alcon Research",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "7 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "7 Years and older"
      },
      "enrollment_count": 140,
      "start_date": "2024-08-30",
      "completion_date": "2025-03-11",
      "has_results": false,
      "last_update_posted_date": "2025-07-20",
      "last_synced_at": "2026-10-09T15:37:54.884Z",
      "location_count": 12,
      "location_summary": "San Diego, California • Jacksonville, Florida • Orlando, Florida + 9 more",
      "locations": [
        {
          "city": "San Diego",
          "state": "California"
        },
        {
          "city": "Jacksonville",
          "state": "Florida"
        },
        {
          "city": "Orlando",
          "state": "Florida"
        },
        {
          "city": "Blue Island",
          "state": "Illinois"
        },
        {
          "city": "Chicago",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06462456"
    },
    {
      "nct_id": "NCT00639379",
      "title": "Comparison of Two Toric Contact Lenses on Current Toric Wearers",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Ametropia"
      ],
      "interventions": [
        {
          "name": "senofilcon A toric",
          "type": "DEVICE"
        },
        {
          "name": "alphafilcon A toric",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Johnson & Johnson Vision Care, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "45 Years",
        "sex": "ALL",
        "summary": "18 Years to 45 Years"
      },
      "enrollment_count": 89,
      "start_date": "2008-02",
      "completion_date": "2008-06",
      "has_results": true,
      "last_update_posted_date": "2015-05-21",
      "last_synced_at": "2026-10-09T15:37:54.884Z",
      "location_count": 7,
      "location_summary": "Jacksonville, Florida • Orlando, Florida • Morrow, Georgia + 4 more",
      "locations": [
        {
          "city": "Jacksonville",
          "state": "Florida"
        },
        {
          "city": "Orlando",
          "state": "Florida"
        },
        {
          "city": "Morrow",
          "state": "Georgia"
        },
        {
          "city": "St Louis",
          "state": "Missouri"
        },
        {
          "city": "Concord",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00639379"
    }
  ]
}