{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Single+Injection+of+Local+Anesthetic&page=2",
    "query": {
      "intervention": "Single Injection of Local Anesthetic",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 10,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Single+Injection+of+Local+Anesthetic&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-09-26T07:13:42.277Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT05005260",
      "title": "Liposomal Bupivacaine Single-Injection Interscalene Block vs. Continuous Interscalene Block for Primary Total Shoulder Arthroplasty",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Pain, Postoperative",
        "Brachial Plexus Block"
      ],
      "interventions": [
        {
          "name": "Bupivacaine HCl",
          "type": "DRUG"
        },
        {
          "name": "Liposomal bupivacaine + Bupivacaine Hcl 0.5% Inj",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Mayo Clinic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 88,
      "start_date": "2021-10-14",
      "completion_date": "2023-03-18",
      "has_results": true,
      "last_update_posted_date": "2024-05-07",
      "last_synced_at": "2026-09-26T07:13:42.277Z",
      "location_count": 1,
      "location_summary": "Rochester, Minnesota",
      "locations": [
        {
          "city": "Rochester",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05005260"
    },
    {
      "nct_id": "NCT03504111",
      "title": "PRINT Trial (Platelet Rich Injection vs Needle Tenotomy)",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Lateral Epicondylitis",
        "Tendinosis",
        "Elbow, Tennis",
        "Elbows Tendonitis"
      ],
      "interventions": [
        {
          "name": "Percutaneous Needle Tenotomy",
          "type": "PROCEDURE"
        },
        {
          "name": "PRP",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Kaiser Permanente",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 50,
      "start_date": "2016-07",
      "completion_date": "2019-12-31",
      "has_results": false,
      "last_update_posted_date": "2019-03-13",
      "last_synced_at": "2026-09-26T07:13:42.277Z",
      "location_count": 1,
      "location_summary": "Los Angeles, California",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03504111"
    },
    {
      "nct_id": "NCT02297191",
      "title": "Ultrasound Guided Local Anesthetic Block: Thoracolumbar Interfascial Plane",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Healthy"
      ],
      "interventions": [
        {
          "name": "Thoracolumbar Interfascial Plane Block",
          "type": "PROCEDURE"
        },
        {
          "name": "Ropivicaine",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "PROCEDURE",
        "DRUG"
      ],
      "sponsor": "Medical University of South Carolina",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 10,
      "start_date": "2014-07",
      "completion_date": "2014-11",
      "has_results": false,
      "last_update_posted_date": "2018-06-20",
      "last_synced_at": "2026-09-26T07:13:42.277Z",
      "location_count": 1,
      "location_summary": "Charleston, South Carolina",
      "locations": [
        {
          "city": "Charleston",
          "state": "South Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02297191"
    },
    {
      "nct_id": "NCT02876055",
      "title": "Analgesic Efficacy of Interscalene Nerve Block Versus Local Infiltration Analgesia Following Total Shoulder Arthroplasty",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Pain, Postoperative"
      ],
      "interventions": [
        {
          "name": "Single shot interscalene nerve block",
          "type": "DRUG"
        },
        {
          "name": "Continuous interscalene nerve block",
          "type": "DRUG"
        },
        {
          "name": "Local Infiltration Analgesia (LIA)",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Mayo Clinic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 125,
      "start_date": "2016-11",
      "completion_date": "2018-02",
      "has_results": true,
      "last_update_posted_date": "2019-04-16",
      "last_synced_at": "2026-09-26T07:13:42.277Z",
      "location_count": 1,
      "location_summary": "Rochester, Minnesota",
      "locations": [
        {
          "city": "Rochester",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02876055"
    },
    {
      "nct_id": "NCT01586806",
      "title": "Comparing Subsartorial Saphenous Nerve Blocks With and Without Dexamethasone for Anterior Cruciate Ligament Reconstruction",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Anterior Cruciate Ligament Reconstruction",
        "Regional Anesthesia, Saphenous Nerve Block"
      ],
      "interventions": [
        {
          "name": "Bupivacaine Only",
          "type": "DRUG"
        },
        {
          "name": "Bupivacaine with 1 mg of Dexamethasone",
          "type": "DRUG"
        },
        {
          "name": "Bupivacaine with 4 mg of Dexamethasone",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Hospital for Special Surgery, New York",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "16 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "16 Years to 65 Years"
      },
      "enrollment_count": 195,
      "start_date": "2012-07",
      "completion_date": "2014-12",
      "has_results": true,
      "last_update_posted_date": "2016-11-28",
      "last_synced_at": "2026-09-26T07:13:42.277Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01586806"
    },
    {
      "nct_id": "NCT03838250",
      "title": "Study to Evaluate Hepatic Artery Injection of Autologous Human Bone Marrow-Derived MSCs in Patients With Alcoholic LC",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Alcoholic Liver Cirrhosis"
      ],
      "interventions": [
        {
          "name": "Cellgram™ (Bone marrow-derived MSCs)",
          "type": "BIOLOGICAL"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL"
      ],
      "sponsor": "Pharmicell Co., Ltd.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "18 Years to 70 Years"
      },
      "enrollment_count": 10,
      "start_date": "2019-06-20",
      "completion_date": "2021-06",
      "has_results": false,
      "last_update_posted_date": "2020-10-22",
      "last_synced_at": "2026-09-26T07:13:42.277Z",
      "location_count": 1,
      "location_summary": "Salt Lake City, Utah",
      "locations": [
        {
          "city": "Salt Lake City",
          "state": "Utah"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03838250"
    },
    {
      "nct_id": "NCT03807505",
      "title": "Erector Spinae Plane Versus Interscalene Blocks for Shoulder Surgery",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Anesthesia, Local",
        "Phrenic Nerve Paralysis",
        "Upper Extremity Injury",
        "Shoulder Injury"
      ],
      "interventions": [
        {
          "name": "Interscalene brachial plexus nerve block",
          "type": "PROCEDURE"
        },
        {
          "name": "Erector spinae plane block",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Stanford University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 30,
      "start_date": "2019-06-13",
      "completion_date": "2019-12-31",
      "has_results": false,
      "last_update_posted_date": "2020-03-05",
      "last_synced_at": "2026-09-26T07:13:42.277Z",
      "location_count": 1,
      "location_summary": "Palo Alto, California",
      "locations": [
        {
          "city": "Palo Alto",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03807505"
    },
    {
      "nct_id": "NCT02329951",
      "title": "Predictive Factors for LBP Interventional Treatment Outcomes",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Low Back Pain",
        "Lumbar Radiculopathy"
      ],
      "interventions": [
        {
          "name": "Facet intervention",
          "type": "PROCEDURE"
        },
        {
          "name": "Sacroiliac joint injection",
          "type": "PROCEDURE"
        },
        {
          "name": "Epidural steroid injection",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Johns Hopkins University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 346,
      "start_date": "2014-12",
      "completion_date": "2021-12",
      "has_results": false,
      "last_update_posted_date": "2021-12-09",
      "last_synced_at": "2026-09-26T07:13:42.277Z",
      "location_count": 1,
      "location_summary": "Baltimore, Maryland",
      "locations": [
        {
          "city": "Baltimore",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02329951"
    },
    {
      "nct_id": "NCT01786655",
      "title": "Safety Study of Long-Acting Local Anesthetic",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Safety of Neosaxitoxin in Healthy Volunteers"
      ],
      "interventions": [
        {
          "name": "Neosaxitoxin in saline",
          "type": "DRUG"
        },
        {
          "name": "NeoSTX + bupivacaine 0.2%",
          "type": "DRUG"
        },
        {
          "name": "NeoSTX + bupivacaine 0.2% + epinephrine 5mcg/ml",
          "type": "DRUG"
        },
        {
          "name": "Saline placebo",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER"
      ],
      "sponsor": "Charles Berde",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "35 Years",
        "sex": "MALE",
        "summary": "18 Years to 35 Years · Male only"
      },
      "enrollment_count": 105,
      "start_date": "2013-05",
      "completion_date": "2014-04",
      "has_results": false,
      "last_update_posted_date": "2016-02-17",
      "last_synced_at": "2026-09-26T07:13:42.277Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01786655"
    },
    {
      "nct_id": "NCT03779659",
      "title": "Effectiveness of Synapse Transcutaneous Electronic Nerve Stimulation (TENS) During Dental Procedures Among Children",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Dental Fear",
        "Anesthesia, Local",
        "Pediatric Dentistry"
      ],
      "interventions": [
        {
          "name": "Synapse TENS device",
          "type": "DEVICE"
        },
        {
          "name": "Topical anesthetic gel",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "DRUG"
      ],
      "sponsor": "Boston University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "6 Years",
        "maximum_age": "14 Years",
        "sex": "ALL",
        "summary": "6 Years to 14 Years"
      },
      "enrollment_count": 0,
      "start_date": "2021-07",
      "completion_date": "2023-02",
      "has_results": false,
      "last_update_posted_date": "2021-06-08",
      "last_synced_at": "2026-09-26T07:13:42.277Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03779659"
    }
  ]
}