{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Sirolimus+0.2%25", "query": { "intervention": "Sirolimus 0.2%" }, "page_size": 10 }, "pagination": { "page": 1, "page_size": 10, "total_count": 8, "total_pages": 1, "next_page_url": null, "previous_page_url": null }, "source": "remote", "last_synced_at": "2026-09-15T16:25:28.730Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT02959918", "title": "Multi-Dose Safety/Pharmacodynamic Study of SEL-212/SEL-037 in Subjects With Symptomatic Gout & Elevated Blood Uric Acid", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Gout Chronic", "Hyperuricemia" ], "interventions": [ { "name": "SEL-212", "type": "DRUG" }, { "name": "SEL-037", "type": "DRUG" }, { "name": "SVP-rapamycin (SEL-110)", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Selecta Biosciences, Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "21 Years", "maximum_age": "75 Years", "sex": "ALL", "summary": "21 Years to 75 Years" }, "enrollment_count": 152, "start_date": "2016-10", "completion_date": "2019-01", "has_results": true, "last_update_posted_date": "2022-02-14", "last_synced_at": "2026-09-15T16:25:28.730Z", "location_count": 13, "location_summary": "Anaheim, California • El Cajon, California • Irvine, California + 10 more", "locations": [ { "city": "Anaheim", "state": "California" }, { "city": "El Cajon", "state": "California" }, { "city": "Irvine", "state": "California" }, { "city": "Clearwater", "state": "Florida" }, { "city": "DeBary", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT02959918" }, { "nct_id": "NCT07813533", "title": "A Pilot Study to Examine the Efficacy and Tolerability of Sirolimus on Epidermal Nevi Lesions in Patients 6 Years Old and Above.", "overall_status": "NOT_YET_RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "EARLY_PHASE1" ], "conditions": [ "Epidermal Nevi" ], "interventions": [ { "name": "sirolimus topical gel 0.2%", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Northwestern University", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "6 Years", "maximum_age": null, "sex": "ALL", "summary": "6 Years and older" }, "enrollment_count": 14, "start_date": "2026-10", "completion_date": "2028-12", "has_results": false, "last_update_posted_date": "2026-09-10", "last_synced_at": "2026-09-15T16:25:28.730Z", "location_count": 1, "location_summary": "Chicago, Illinois", "locations": [ { "city": "Chicago", "state": "Illinois" } ], "official_url": "https://clinicaltrials.gov/study/NCT07813533" }, { "nct_id": "NCT03972462", "title": "NPC-12G Gel 0.2% Sirolimus PK Bridging Study", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Bioavailability Study" ], "interventions": [ { "name": "NPC-12G Gel 0.2%", "type": "DRUG" }, { "name": "Rapamune® 2 mg tablet", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Nobelpharma", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "18 Years to 65 Years" }, "enrollment_count": 12, "start_date": "2019-05-31", "completion_date": "2019-06-17", "has_results": false, "last_update_posted_date": "2020-03-06", "last_synced_at": "2026-09-15T16:25:28.730Z", "location_count": 1, "location_summary": "Miami, Florida", "locations": [ { "city": "Miami", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT03972462" }, { "nct_id": "NCT03363763", "title": "Topical Sirolimus Ointment for Cutaneous Angiofibromas in Subjects With Tuberous Sclerosis Complex", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Angiofibroma of Face", "Tuberous Sclerosis" ], "interventions": [ { "name": "Sirolimus 0.2%", "type": "DRUG" }, { "name": "Sirolimus 0.4%", "type": "DRUG" }, { "name": "Placebo ointment", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Aucta Pharmaceuticals, Inc", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "2 Years", "maximum_age": "21 Years", "sex": "ALL", "summary": "2 Years to 21 Years" }, "enrollment_count": 24, "start_date": "2017-04-12", "completion_date": "2023-03-24", "has_results": true, "last_update_posted_date": "2025-12-01", "last_synced_at": "2026-09-15T16:25:28.730Z", "location_count": 7, "location_summary": "Phoenix, Arizona • Los Angeles, California • Aurora, Colorado + 4 more", "locations": [ { "city": "Phoenix", "state": "Arizona" }, { "city": "Los Angeles", "state": "California" }, { "city": "Aurora", "state": "Colorado" }, { "city": "Atlanta", "state": "Georgia" }, { "city": "Boston", "state": "Massachusetts" } ], "official_url": "https://clinicaltrials.gov/study/NCT03363763" }, { "nct_id": "NCT06940895", "title": "Evaluating the Safety and Efficacy of Topical Sirolimus 0.2% to Treat Acanthosis Nigricans", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Acanthosis Nigricans" ], "interventions": [ { "name": "Sirolimus 0.2%", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Narrows Institute for Biomedical Research", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 5, "start_date": "2025-03-01", "completion_date": "2025-07-18", "has_results": false, "last_update_posted_date": "2025-11-28", "last_synced_at": "2026-09-15T16:25:28.730Z", "location_count": 1, "location_summary": "Brooklyn, New York", "locations": [ { "city": "Brooklyn", "state": "New York" } ], "official_url": "https://clinicaltrials.gov/study/NCT06940895" }, { "nct_id": "NCT00117598", "title": "Study Evaluating Temsirolimus (CCI-779) In Mantle Cell Lymphoma (MCL)", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Lymphoma" ], "interventions": [ { "name": "Temsirolimus (CCI-779)", "type": "DRUG" }, { "name": "Investigator's choice", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Pfizer", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 169, "start_date": "2005-05", "completion_date": "2011-01", "has_results": true, "last_update_posted_date": "2015-03-30", "last_synced_at": "2026-09-15T16:25:28.730Z", "location_count": 19, "location_summary": "Little Rock, Arkansas • Fountain Valley, California • Los Angeles, California + 16 more", "locations": [ { "city": "Little Rock", "state": "Arkansas" }, { "city": "Fountain Valley", "state": "California" }, { "city": "Los Angeles", "state": "California" }, { "city": "New Milford", "state": "Connecticut" }, { "city": "Washington D.C.", "state": "District of Columbia" } ], "official_url": "https://clinicaltrials.gov/study/NCT00117598" }, { "nct_id": "NCT00679042", "title": "Islet Transplantation in Type 1 Diabetic Patients Using the University of Illinois at Chicago (UIC) Protocol", "overall_status": "ACTIVE_NOT_RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Type 1 Diabetes Mellitus" ], "interventions": [ { "name": "Islets of Langerhans transplantation", "type": "BIOLOGICAL" } ], "intervention_types": [ "BIOLOGICAL" ], "sponsor": "CellTrans Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "75 Years", "sex": "ALL", "summary": "18 Years to 75 Years" }, "enrollment_count": 21, "start_date": "2007-09-05", "completion_date": "2026-06-14", "has_results": true, "last_update_posted_date": "2026-04-06", "last_synced_at": "2026-09-15T16:25:28.730Z", "location_count": 1, "location_summary": "Chicago, Illinois", "locations": [ { "city": "Chicago", "state": "Illinois" } ], "official_url": "https://clinicaltrials.gov/study/NCT00679042" }, { "nct_id": "NCT00014911", "title": "Islet Transplantation for Type 1 Diabetes", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Diabetes Mellitus, Insulin-Dependent" ], "interventions": [ { "name": "Islet Transplantation", "type": "PROCEDURE" }, { "name": "Sirolimus", "type": "DRUG" }, { "name": "Tacrolimus", "type": "DRUG" }, { "name": "Daclizumab", "type": "DRUG" }, { "name": "Sulfamethoxazole", "type": "DRUG" }, { "name": "Ganciclovir", "type": "DRUG" }, { "name": "Trimethoprim", "type": "DRUG" }, { "name": "Pentamidine", "type": "DRUG" } ], "intervention_types": [ "PROCEDURE", "DRUG" ], "sponsor": "National Institute of Allergy and Infectious Diseases (NIAID)", "sponsor_class": "NIH", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "18 Years to 65 Years" }, "enrollment_count": 36, "start_date": "2001-04", "completion_date": "2010-08", "has_results": true, "last_update_posted_date": "2017-03-15", "last_synced_at": "2026-09-15T16:25:28.730Z", "location_count": 5, "location_summary": "Miami, Florida • Boston, Massachusetts • Minneapolis, Minnesota + 2 more", "locations": [ { "city": "Miami", "state": "Florida" }, { "city": "Boston", "state": "Massachusetts" }, { "city": "Minneapolis", "state": "Minnesota" }, { "city": "St Louis", "state": "Missouri" }, { "city": "Seattle", "state": "Washington" } ], "official_url": "https://clinicaltrials.gov/study/NCT00014911" } ] }