{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Skeletal+loading",
    "query": {
      "intervention": "Skeletal loading"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 12,
    "total_pages": 2,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Skeletal+loading&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-02T23:13:15.249Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT03888040",
      "title": "Fatigability of Lower Limb Muscle in Older Adults: Protective Effects of Strength Training Exercise in Old Men and Women",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Aging"
      ],
      "interventions": [
        {
          "name": "Exercise",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Marquette University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "100 Years",
        "sex": "ALL",
        "summary": "18 Years to 100 Years"
      },
      "enrollment_count": 120,
      "start_date": "2020-09-01",
      "completion_date": "2025-08-31",
      "has_results": false,
      "last_update_posted_date": "2025-02-11",
      "last_synced_at": "2026-09-02T23:13:15.249Z",
      "location_count": 1,
      "location_summary": "Milwaukee, Wisconsin",
      "locations": [
        {
          "city": "Milwaukee",
          "state": "Wisconsin"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03888040"
    },
    {
      "nct_id": "NCT04028726",
      "title": "Skeletal Muscle Protein Synthesis: Traditional and Cluster Sets",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Resistance Exercise"
      ],
      "interventions": [
        {
          "name": "Back-squat exercise",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Illinois at Urbana-Champaign",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "20 Years",
        "maximum_age": "35 Years",
        "sex": "ALL",
        "summary": "20 Years to 35 Years"
      },
      "enrollment_count": 8,
      "start_date": "2018-08-25",
      "completion_date": "2019-07-15",
      "has_results": false,
      "last_update_posted_date": "2019-07-24",
      "last_synced_at": "2026-09-02T23:13:15.249Z",
      "location_count": 1,
      "location_summary": "Urbana, Illinois",
      "locations": [
        {
          "city": "Urbana",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04028726"
    },
    {
      "nct_id": "NCT03479008",
      "title": "Testing of a New Therapeutic Vibration Device to Reduce Neuromuscular Weakness in Hospitalized Patients",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Critically Ill",
        "Post Intensive Care Syndrome"
      ],
      "interventions": [
        {
          "name": "Therapeutic Vibration Device",
          "type": "DIAGNOSTIC_TEST"
        }
      ],
      "intervention_types": [
        "DIAGNOSTIC_TEST"
      ],
      "sponsor": "University of Michigan",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 36,
      "start_date": "2018-03-26",
      "completion_date": "2019-03-22",
      "has_results": true,
      "last_update_posted_date": "2024-05-30",
      "last_synced_at": "2026-09-02T23:13:15.249Z",
      "location_count": 1,
      "location_summary": "Ann Arbor, Michigan",
      "locations": [
        {
          "city": "Ann Arbor",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03479008"
    },
    {
      "nct_id": "NCT00729378",
      "title": "Jump-In: Building Better Bones",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Adolescent Development"
      ],
      "interventions": [
        {
          "name": "Skeletal loading",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Arizona",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "9 Years",
        "maximum_age": "12 Years",
        "sex": "FEMALE",
        "summary": "9 Years to 12 Years · Female only"
      },
      "enrollment_count": 509,
      "start_date": "2007-04",
      "completion_date": "2013-04",
      "has_results": true,
      "last_update_posted_date": "2025-10-28",
      "last_synced_at": "2026-09-02T23:13:15.249Z",
      "location_count": 1,
      "location_summary": "Tucson, Arizona",
      "locations": [
        {
          "city": "Tucson",
          "state": "Arizona"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00729378"
    },
    {
      "nct_id": "NCT01714479",
      "title": "Skeletal Muscle Response to Amino Acids and Load Carriage Exercise",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Muscle Loss",
        "Muscle Anabolism",
        "Muscle Performance"
      ],
      "interventions": [
        {
          "name": "Leucine-enriched nutritional supplement",
          "type": "OTHER"
        },
        {
          "name": "Placebo",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "United States Army Research Institute of Environmental Medicine",
      "sponsor_class": "FED",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "39 Years",
        "sex": "ALL",
        "summary": "18 Years to 39 Years"
      },
      "enrollment_count": 40,
      "start_date": "2012-10",
      "completion_date": "2013-11",
      "has_results": false,
      "last_update_posted_date": "2017-07-21",
      "last_synced_at": "2026-09-02T23:13:15.249Z",
      "location_count": 1,
      "location_summary": "Natick, Massachusetts",
      "locations": [
        {
          "city": "Natick",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01714479"
    },
    {
      "nct_id": "NCT06972862",
      "title": "Bone and Body Composition Adaptations to Physical Training",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Exercise",
        "Healthy"
      ],
      "interventions": [
        {
          "name": "Osteogenic Index Optimized Exercise Training Program",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Pittsburgh",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "40 Years",
        "sex": "ALL",
        "summary": "18 Years to 40 Years"
      },
      "enrollment_count": 206,
      "start_date": "2022-08-29",
      "completion_date": "2025-04-27",
      "has_results": false,
      "last_update_posted_date": "2026-08-17",
      "last_synced_at": "2026-09-02T23:13:15.249Z",
      "location_count": 2,
      "location_summary": "Lawrence, Kansas • Pittsburgh, Pennsylvania",
      "locations": [
        {
          "city": "Lawrence",
          "state": "Kansas"
        },
        {
          "city": "Pittsburgh",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06972862"
    },
    {
      "nct_id": "NCT04151901",
      "title": "Sex-specific Determinants of Early-phase Recovery From Skeletal Muscle Disuse",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Atrophy of Muscle Due to Disuse",
        "Rehabilitation"
      ],
      "interventions": [
        {
          "name": "Resistance Exercise Rehabilitation",
          "type": "OTHER"
        },
        {
          "name": "Walking-based rehabilitation",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "The University of Texas Health Science Center at San Antonio",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "50 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "50 Years to 65 Years"
      },
      "enrollment_count": 37,
      "start_date": "2021-08-27",
      "completion_date": "2026-12",
      "has_results": false,
      "last_update_posted_date": "2026-06-04",
      "last_synced_at": "2026-09-02T23:13:15.249Z",
      "location_count": 2,
      "location_summary": "Galveston, Texas • San Antonio, Texas",
      "locations": [
        {
          "city": "Galveston",
          "state": "Texas"
        },
        {
          "city": "San Antonio",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04151901"
    },
    {
      "nct_id": "NCT03952884",
      "title": "Skeletal Muscle Protein Synthetic Response to Amino Acid and Peptides",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Protein Metabolism"
      ],
      "interventions": [
        {
          "name": "Resistance Exercise",
          "type": "BEHAVIORAL"
        },
        {
          "name": "No Resistance Exercise",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Leucine",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Dileucine",
          "type": "DIETARY_SUPPLEMENT"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL",
        "DIETARY_SUPPLEMENT"
      ],
      "sponsor": "University of Illinois at Urbana-Champaign",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "35 Years",
        "sex": "ALL",
        "summary": "18 Years to 35 Years"
      },
      "enrollment_count": 10,
      "start_date": "2019-05-03",
      "completion_date": "2019-11-20",
      "has_results": false,
      "last_update_posted_date": "2020-09-28",
      "last_synced_at": "2026-09-02T23:13:15.249Z",
      "location_count": 1,
      "location_summary": "Urbana, Illinois",
      "locations": [
        {
          "city": "Urbana",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03952884"
    },
    {
      "nct_id": "NCT03957226",
      "title": "An Osseoanchored Percutaneous Prosthesis Study Evaluating Stable Neural Signal Transmission in Subjects With Transhumeral Amputations",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Amputation Neuroma",
        "Amputation",
        "Prosthesis User"
      ],
      "interventions": [
        {
          "name": "e-OPRA (electronic-Osseoanchored Prosthese for the Rehabilitation of Amputees)",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of Michigan",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "22 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "22 Years to 65 Years"
      },
      "enrollment_count": 0,
      "start_date": "2020-01-30",
      "completion_date": "2022-06-23",
      "has_results": false,
      "last_update_posted_date": "2024-10-04",
      "last_synced_at": "2026-09-02T23:13:15.249Z",
      "location_count": 1,
      "location_summary": "Ann Arbor, Michigan",
      "locations": [
        {
          "city": "Ann Arbor",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03957226"
    },
    {
      "nct_id": "NCT04083794",
      "title": "Exploration of Blood Flow Regulation to Bone in Humans",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Bone Blood Flow Regulation"
      ],
      "interventions": [
        {
          "name": "Laboratory based assessments",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Spaulding Rehabilitation Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "40 Years",
        "sex": "ALL",
        "summary": "18 Years to 40 Years"
      },
      "enrollment_count": 90,
      "start_date": "2018-05-31",
      "completion_date": "2023-04-13",
      "has_results": true,
      "last_update_posted_date": "2024-06-17",
      "last_synced_at": "2026-09-02T23:13:15.249Z",
      "location_count": 1,
      "location_summary": "Cambridge, Massachusetts",
      "locations": [
        {
          "city": "Cambridge",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04083794"
    }
  ]
}