{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Skeletal+muscle+biopsy&page=2",
    "query": {
      "intervention": "Skeletal muscle biopsy",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 31,
    "total_pages": 4,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Skeletal+muscle+biopsy&page=3&page_size=10",
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Skeletal+muscle+biopsy&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-10-08T18:06:08.578Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT03407833",
      "title": "Physiologic and Functional Adaptations of Insulin Sensitive Tissues",
      "overall_status": "ENROLLING_BY_INVITATION",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Diabetes",
        "Insulin Resistance",
        "Obesity",
        "Bariatric Surgery Candidate",
        "Roux-en-y Gastric Bypass",
        "Liver Diseases"
      ],
      "interventions": [
        {
          "name": "Endoscopy biopsy",
          "type": "OTHER"
        },
        {
          "name": "Surgical biopsy",
          "type": "OTHER"
        },
        {
          "name": "Mixed-meal tolerance test",
          "type": "OTHER"
        },
        {
          "name": "Excised Liver Tissue Sampling",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Vanderbilt University Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 500,
      "start_date": "2018-02-13",
      "completion_date": "2028-02",
      "has_results": false,
      "last_update_posted_date": "2025-12-18",
      "last_synced_at": "2026-10-08T18:06:08.578Z",
      "location_count": 1,
      "location_summary": "Nashville, Tennessee",
      "locations": [
        {
          "city": "Nashville",
          "state": "Tennessee"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03407833"
    },
    {
      "nct_id": "NCT03350906",
      "title": "Enhancing Adaptations to Exercise",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Inflammation"
      ],
      "interventions": [
        {
          "name": "n3-PUFA",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        },
        {
          "name": "Biopsy",
          "type": "PROCEDURE"
        },
        {
          "name": "Body Composition Scan",
          "type": "DIAGNOSTIC_TEST"
        }
      ],
      "intervention_types": [
        "DRUG",
        "PROCEDURE",
        "DIAGNOSTIC_TEST"
      ],
      "sponsor": "Mayo Clinic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "20 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "20 Years to 85 Years"
      },
      "enrollment_count": 63,
      "start_date": "2018-01-01",
      "completion_date": "2021-12-31",
      "has_results": true,
      "last_update_posted_date": "2023-11-14",
      "last_synced_at": "2026-10-08T18:06:08.578Z",
      "location_count": 1,
      "location_summary": "Rochester, Minnesota",
      "locations": [
        {
          "city": "Rochester",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03350906"
    },
    {
      "nct_id": "NCT04334343",
      "title": "Investigating the Effects of Aerobic and Resistance Training in Vivo on Skeletal Muscle Metabolism in Vitro in Primary Human Muscle Cells (MoTrMyo)",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Physical Activity"
      ],
      "interventions": [
        {
          "name": "Additional Muscle Biopsy Collection",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "AdventHealth Translational Research Institute",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 179,
      "start_date": "2020-11-01",
      "completion_date": "2026-12",
      "has_results": false,
      "last_update_posted_date": "2026-03-30",
      "last_synced_at": "2026-10-08T18:06:08.578Z",
      "location_count": 1,
      "location_summary": "Orlando, Florida",
      "locations": [
        {
          "city": "Orlando",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04334343"
    },
    {
      "nct_id": "NCT04371237",
      "title": "Accelerating Post-exercise Muscle Glycogen Resynthesis in Humans: Impact of Combined Nutrient Intake and Intermittent Pneumatic Compression or Heat Therapy",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Muscle Recovery",
        "Muscle Soreness",
        "Glycogen Depletion"
      ],
      "interventions": [
        {
          "name": "Compression sleeve",
          "type": "DEVICE"
        },
        {
          "name": "Heat therapy",
          "type": "DEVICE"
        },
        {
          "name": "Glycogen-depleting exercise session",
          "type": "OTHER"
        },
        {
          "name": "Nutrient Intake (beverage)",
          "type": "OTHER"
        },
        {
          "name": "Skeletal muscle biopsy",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "OTHER",
        "PROCEDURE"
      ],
      "sponsor": "PepsiCo Global R&D",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "35 Years",
        "sex": "ALL",
        "summary": "18 Years to 35 Years"
      },
      "enrollment_count": 26,
      "start_date": "2018-09-19",
      "completion_date": "2019-12-21",
      "has_results": false,
      "last_update_posted_date": "2021-03-10",
      "last_synced_at": "2026-10-08T18:06:08.578Z",
      "location_count": 1,
      "location_summary": "West Lafayette, Indiana",
      "locations": [
        {
          "city": "West Lafayette",
          "state": "Indiana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04371237"
    },
    {
      "nct_id": "NCT02685098",
      "title": "A Clinical and Histological Analysis of Mesenchymal Stem Cells in Amputation",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Ischemia",
        "Peripheral Arterial Disease",
        "Peripheral Vascular Disease",
        "Vascular Disease",
        "Arterial Occlusive Disease",
        "Arteriosclerosis",
        "Atherosclerosis",
        "Cardiovascular Disease",
        "Pathologic Processes",
        "Orthopedic Procedures",
        "Amputation"
      ],
      "interventions": [
        {
          "name": "Allogeneic bone marrow derived mesenchymal stem cells",
          "type": "BIOLOGICAL"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL"
      ],
      "sponsor": "Indiana University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "40 Years",
        "maximum_age": "90 Years",
        "sex": "ALL",
        "summary": "40 Years to 90 Years"
      },
      "enrollment_count": 81,
      "start_date": "2017-01-23",
      "completion_date": "2023-10-03",
      "has_results": false,
      "last_update_posted_date": "2025-09-23",
      "last_synced_at": "2026-10-08T18:06:08.578Z",
      "location_count": 1,
      "location_summary": "Indianapolis, Indiana",
      "locations": [
        {
          "city": "Indianapolis",
          "state": "Indiana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02685098"
    },
    {
      "nct_id": "NCT05820490",
      "title": "ImpaCt Of Shiftwork on METabolic Flexibility and Skeletal Muscle Clocks",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Metabolic Health"
      ],
      "interventions": [
        {
          "name": "Whole Room Calorimeter",
          "type": "OTHER"
        },
        {
          "name": "Mixed-Meal Tolerance Test (MMTT)",
          "type": "OTHER"
        },
        {
          "name": "Core Body Temperature",
          "type": "OTHER"
        },
        {
          "name": "Morningness-Eveningness Questionnaire",
          "type": "OTHER"
        },
        {
          "name": "Muscle Biopsy",
          "type": "PROCEDURE"
        },
        {
          "name": "Serial Blood Sampling",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER",
        "PROCEDURE"
      ],
      "sponsor": "AdventHealth Translational Research Institute",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "45 Years",
        "sex": "ALL",
        "summary": "21 Years to 45 Years"
      },
      "enrollment_count": 40,
      "start_date": "2023-07-28",
      "completion_date": "2026-01-31",
      "has_results": false,
      "last_update_posted_date": "2026-04-15",
      "last_synced_at": "2026-10-08T18:06:08.578Z",
      "location_count": 1,
      "location_summary": "Orlando, Florida",
      "locations": [
        {
          "city": "Orlando",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05820490"
    },
    {
      "nct_id": "NCT04226131",
      "title": "MusculRA: The Effects of Rheumatoid Arthritis on Skeletal Muscle Biomechanics",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Rheumatoid Arthritis",
        "Healthy Controls"
      ],
      "interventions": [
        {
          "name": "Blood Draw",
          "type": "OTHER"
        },
        {
          "name": "Disease Activity (DAS-28) Assessment",
          "type": "OTHER"
        },
        {
          "name": "Skeletal Muscle Mitochondrial Respiratory Capacity",
          "type": "OTHER"
        },
        {
          "name": "Muscle Biopsy",
          "type": "OTHER"
        },
        {
          "name": "Body Composition",
          "type": "OTHER"
        },
        {
          "name": "Cardiopulmonary Exercise Test (CPET)",
          "type": "OTHER"
        },
        {
          "name": "Strength Testing",
          "type": "OTHER"
        },
        {
          "name": "Questionnaires",
          "type": "OTHER"
        },
        {
          "name": "Skeletal Muscle Biomechanical Property Assessment",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Duke University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "25 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "25 Years to 75 Years"
      },
      "enrollment_count": 21,
      "start_date": "2020-09-09",
      "completion_date": "2023-07-07",
      "has_results": false,
      "last_update_posted_date": "2023-07-13",
      "last_synced_at": "2026-10-08T18:06:08.578Z",
      "location_count": 1,
      "location_summary": "Durham, North Carolina",
      "locations": [
        {
          "city": "Durham",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04226131"
    },
    {
      "nct_id": "NCT00899158",
      "title": "Biological Markers in Patients With Pancreatic Cancer Experiencing Weight Loss",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Cachexia",
        "Pancreatic Cancer"
      ],
      "interventions": [
        {
          "name": "immunologic technique",
          "type": "OTHER"
        },
        {
          "name": "laboratory biomarker analysis",
          "type": "OTHER"
        },
        {
          "name": "biopsy",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "OTHER",
        "PROCEDURE"
      ],
      "sponsor": "Case Comprehensive Cancer Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 44,
      "start_date": "2005-06",
      "completion_date": "2008-12",
      "has_results": false,
      "last_update_posted_date": "2015-09-30",
      "last_synced_at": "2026-10-08T18:06:08.578Z",
      "location_count": 1,
      "location_summary": "Cleveland, Ohio",
      "locations": [
        {
          "city": "Cleveland",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00899158"
    },
    {
      "nct_id": "NCT07516509",
      "title": "Determining Cell- and Spatially-distinct Skeletal Muscle Transcriptional Aberrations in Insulin Resistance",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Insulin Resistance"
      ],
      "interventions": [
        {
          "name": "VO2 Max",
          "type": "OTHER"
        },
        {
          "name": "DEXA",
          "type": "OTHER"
        },
        {
          "name": "Peripheral Microvascular Reactivity",
          "type": "OTHER"
        },
        {
          "name": "Skeletal Muscle Insulin Sensitivity",
          "type": "OTHER"
        },
        {
          "name": "Non-Oxidative Glucose Disposal",
          "type": "OTHER"
        },
        {
          "name": "Muscle tissue Biopsy",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "AdventHealth Translational Research Institute",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "30 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "30 Years to 65 Years"
      },
      "enrollment_count": 36,
      "start_date": "2026-06-11",
      "completion_date": "2028-12",
      "has_results": false,
      "last_update_posted_date": "2026-08-12",
      "last_synced_at": "2026-10-08T18:06:08.578Z",
      "location_count": 1,
      "location_summary": "Orlando, Florida",
      "locations": [
        {
          "city": "Orlando",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07516509"
    },
    {
      "nct_id": "NCT00094796",
      "title": "Rosiglitazone to Reverse Metabolic Defects in Diabetes",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Diabetes Mellitus, Type II",
        "Insulin Resistance"
      ],
      "interventions": [
        {
          "name": "Exercise cardiopulmonary metabolic testing",
          "type": "PROCEDURE"
        },
        {
          "name": "Skeletal muscle biopsy",
          "type": "PROCEDURE"
        },
        {
          "name": "Brachial artery reactivity testing",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "National Heart, Lung, and Blood Institute (NHLBI)",
      "sponsor_class": "NIH",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "22 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "22 Years and older"
      },
      "enrollment_count": 70,
      "start_date": "2004-10-20",
      "completion_date": "2008-09-03",
      "has_results": false,
      "last_update_posted_date": "2017-07-02",
      "last_synced_at": "2026-10-08T18:06:08.578Z",
      "location_count": 2,
      "location_summary": "Bethesda, Maryland • Richmond, Virginia",
      "locations": [
        {
          "city": "Bethesda",
          "state": "Maryland"
        },
        {
          "city": "Richmond",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00094796"
    }
  ]
}