{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Skin+Surface+Cooling",
    "query": {
      "intervention": "Skin Surface Cooling"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 12,
    "total_pages": 2,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Skin+Surface+Cooling&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-08T13:53:48.719Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT06293638",
      "title": "Functional Brain Network Changes in Patients Undergoing Deep Brain Stimulation for Essential Tremor",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Essential Tremor"
      ],
      "interventions": [
        {
          "name": "Alcohol",
          "type": "DRUG"
        },
        {
          "name": "Alprazolam",
          "type": "DRUG"
        },
        {
          "name": "Cold Therapy",
          "type": "DEVICE"
        },
        {
          "name": "Peripheral Nerve Stimulation",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "DRUG",
        "DEVICE",
        "PROCEDURE"
      ],
      "sponsor": "The Cleveland Clinic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "30 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "30 Years to 80 Years"
      },
      "enrollment_count": 55,
      "start_date": "2024-03-25",
      "completion_date": "2028-12-31",
      "has_results": false,
      "last_update_posted_date": "2026-05-08",
      "last_synced_at": "2026-09-08T13:53:48.719Z",
      "location_count": 1,
      "location_summary": "Cleveland, Ohio",
      "locations": [
        {
          "city": "Cleveland",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06293638"
    },
    {
      "nct_id": "NCT02832674",
      "title": "Safety and Effectiveness Evaluation of the Device in Achieving Submental Lift",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Skin Laxity"
      ],
      "interventions": [
        {
          "name": "Percutaneous Radiofrequency single treatment",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "ThermiGen, LLC",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "35 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "35 Years to 65 Years"
      },
      "enrollment_count": 72,
      "start_date": "2016-06-25",
      "completion_date": "2017-04-08",
      "has_results": true,
      "last_update_posted_date": "2018-05-01",
      "last_synced_at": "2026-09-08T13:53:48.719Z",
      "location_count": 1,
      "location_summary": "Montclair, New Jersey",
      "locations": [
        {
          "city": "Montclair",
          "state": "New Jersey"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02832674"
    },
    {
      "nct_id": "NCT03681769",
      "title": "Developing Brain Stimulation as a Treatment for Chronic Pain in Opiate Dependent",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "EARLY_PHASE1"
      ],
      "conditions": [
        "Chronic Pain",
        "Opiate Dependence",
        "Lower Back Pain"
      ],
      "interventions": [
        {
          "name": "iTBS to the left dlPFC",
          "type": "DEVICE"
        },
        {
          "name": "Sham iTBS to the left dlPFC",
          "type": "DEVICE"
        },
        {
          "name": "cTBS to the mPFC",
          "type": "DEVICE"
        },
        {
          "name": "Sham cTBS to the mPFC",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Medical University of South Carolina",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "18 Years to 75 Years"
      },
      "enrollment_count": 24,
      "start_date": "2019-02-22",
      "completion_date": "2021-03-19",
      "has_results": true,
      "last_update_posted_date": "2023-02-10",
      "last_synced_at": "2026-09-08T13:53:48.719Z",
      "location_count": 1,
      "location_summary": "Charleston, South Carolina",
      "locations": [
        {
          "city": "Charleston",
          "state": "South Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03681769"
    },
    {
      "nct_id": "NCT01694290",
      "title": "Chemical Ice Packs for Cooling Hyperthermic Patients",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Heat Stroke, Heat Exhaustion"
      ],
      "interventions": [
        {
          "name": "Chemical Cold Pack",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Stanford University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "75 Years",
        "sex": "MALE",
        "summary": "18 Years to 75 Years · Male only"
      },
      "enrollment_count": 8,
      "start_date": "2012-08",
      "completion_date": "2013-07",
      "has_results": false,
      "last_update_posted_date": "2018-11-26",
      "last_synced_at": "2026-09-08T13:53:48.719Z",
      "location_count": 1,
      "location_summary": "Palo Alto, California",
      "locations": [
        {
          "city": "Palo Alto",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01694290"
    },
    {
      "nct_id": "NCT06279897",
      "title": "LBNP Tolerance With Skin Warming After Exercise Cold Stress",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Blood Pressure",
        "Blood Loss"
      ],
      "interventions": [
        {
          "name": "Skin Surface Rewarming",
          "type": "OTHER"
        },
        {
          "name": "Skin Surface Warming",
          "type": "OTHER"
        },
        {
          "name": "Skin Surface Heating",
          "type": "OTHER"
        },
        {
          "name": "Skin Surface Cooling",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Colorado, Colorado Springs",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "40 Years",
        "sex": "ALL",
        "summary": "18 Years to 40 Years"
      },
      "enrollment_count": 10,
      "start_date": "2022-01-24",
      "completion_date": "2026-09-30",
      "has_results": false,
      "last_update_posted_date": "2025-03-27",
      "last_synced_at": "2026-09-08T13:53:48.719Z",
      "location_count": 1,
      "location_summary": "Colorado Springs, Colorado",
      "locations": [
        {
          "city": "Colorado Springs",
          "state": "Colorado"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06279897"
    },
    {
      "nct_id": "NCT06709781",
      "title": "Cardiovascular Responses in Burn Survivors During Exercise",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Burn Injury"
      ],
      "interventions": [
        {
          "name": "Control (no cooling modalities)",
          "type": "OTHER"
        },
        {
          "name": "Water Spray",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Texas Southwestern Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 31,
      "start_date": "2025-01-08",
      "completion_date": "2025-09-05",
      "has_results": false,
      "last_update_posted_date": "2026-06-24",
      "last_synced_at": "2026-09-08T13:53:48.719Z",
      "location_count": 1,
      "location_summary": "Dallas, Texas",
      "locations": [
        {
          "city": "Dallas",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06709781"
    },
    {
      "nct_id": "NCT03579953",
      "title": "Nicotine TMS EFT Smoking Pilot Study",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "EARLY_PHASE1"
      ],
      "conditions": [
        "Smoking",
        "Nicotine Dependence",
        "Addiction",
        "Smoking, Cigarette"
      ],
      "interventions": [
        {
          "name": "Real cTBS",
          "type": "DEVICE"
        },
        {
          "name": "Sham cTBS",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Medical University of South Carolina",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 16,
      "start_date": "2018-05-22",
      "completion_date": "2019-06-10",
      "has_results": false,
      "last_update_posted_date": "2019-08-14",
      "last_synced_at": "2026-09-08T13:53:48.719Z",
      "location_count": 1,
      "location_summary": "Charleston, South Carolina",
      "locations": [
        {
          "city": "Charleston",
          "state": "South Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03579953"
    },
    {
      "nct_id": "NCT04512976",
      "title": "Exercise in Burn Survivors: Cooling Modalities",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Burn Injury"
      ],
      "interventions": [
        {
          "name": "Control (no cooling modalities)",
          "type": "OTHER"
        },
        {
          "name": "Water Spray Only",
          "type": "OTHER"
        },
        {
          "name": "Fan Only",
          "type": "OTHER"
        },
        {
          "name": "Water Spray and Fan",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Texas Southwestern Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 70,
      "start_date": "2021-01-15",
      "completion_date": "2023-03-01",
      "has_results": true,
      "last_update_posted_date": "2025-07-28",
      "last_synced_at": "2026-09-08T13:53:48.719Z",
      "location_count": 1,
      "location_summary": "Dallas, Texas",
      "locations": [
        {
          "city": "Dallas",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04512976"
    },
    {
      "nct_id": "NCT00523588",
      "title": "Treatment of Cutaneous Lupus Erythematosus (CLE) With the 595 nm Flashlamp Pulsed Dye Laser",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Cutaneous Lupus Erythematosus"
      ],
      "interventions": [
        {
          "name": "laser treatment (Candela Vbeam Perfecta™)",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "University of Pennsylvania",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 10,
      "start_date": "2007-03",
      "completion_date": "2010-01",
      "has_results": false,
      "last_update_posted_date": "2010-06-25",
      "last_synced_at": "2026-09-08T13:53:48.719Z",
      "location_count": 1,
      "location_summary": "Philadelphia, Pennsylvania",
      "locations": [
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00523588"
    },
    {
      "nct_id": "NCT04553627",
      "title": "Feasibility of Producing the Appearance of a Gluteal Lift Post Cryolipolysis",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Subcutaneous Fat"
      ],
      "interventions": [
        {
          "name": "ZELTIQ thermoelectric device",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Riverchase Dermatology",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "22 Years",
        "maximum_age": "50 Years",
        "sex": "FEMALE",
        "summary": "22 Years to 50 Years · Female only"
      },
      "enrollment_count": 10,
      "start_date": "2020-07-15",
      "completion_date": "2021-05-30",
      "has_results": false,
      "last_update_posted_date": "2020-10-19",
      "last_synced_at": "2026-09-08T13:53:48.719Z",
      "location_count": 1,
      "location_summary": "Miami, Florida",
      "locations": [
        {
          "city": "Miami",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04553627"
    }
  ]
}