{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Sodium+Fluoride&page=5", "query": { "intervention": "Sodium Fluoride", "page": 5 }, "page_size": 10 }, "pagination": { "page": 5, "page_size": 10, "total_count": 216, "total_pages": 22, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Sodium+Fluoride&page=6&page_size=10", "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Sodium+Fluoride&page=4&page_size=10" }, "source": "remote", "last_synced_at": "2026-10-05T05:08:30.350Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT03936556", "title": "A Clinical Study to Assess the Effects of a Stannous Fluoride Dentifrice on Plaque and Gingivitis", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Gingivitis" ], "interventions": [ { "name": "Marketed toothpaste", "type": "DRUG" }, { "name": "Marketed Cavity Protection Toothpaste", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Procter and Gamble", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 84, "start_date": "2018-02-25", "completion_date": "2018-06-03", "has_results": false, "last_update_posted_date": "2019-12-04", "last_synced_at": "2026-10-05T05:08:30.350Z", "location_count": 1, "location_summary": "Whittier, California", "locations": [ { "city": "Whittier", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT03936556" }, { "nct_id": "NCT03689946", "title": "Effect of Evolocumab on Coronary Atherosclerosis", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Cardiovascular Disease", "Hyperlipidemia" ], "interventions": [ { "name": "Evolocumab", "type": "DRUG" }, { "name": "18F-NaF PET", "type": "DIAGNOSTIC_TEST" }, { "name": "CCTA", "type": "DIAGNOSTIC_TEST" }, { "name": "Omnipaque", "type": "DRUG" }, { "name": "Metoprolol", "type": "DRUG" }, { "name": "Nitroglycerin", "type": "DRUG" } ], "intervention_types": [ "DRUG", "DIAGNOSTIC_TEST" ], "sponsor": "Cedars-Sinai Medical Center", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 55, "start_date": "2019-03-19", "completion_date": "2023-05-30", "has_results": true, "last_update_posted_date": "2024-07-17", "last_synced_at": "2026-10-05T05:08:30.350Z", "location_count": 1, "location_summary": "Los Angeles, California", "locations": [ { "city": "Los Angeles", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT03689946" }, { "nct_id": "NCT01831817", "title": "Exploratory Study to Evaluate the Efficacy of an Occlusion Based Dentifrice in Relief of Dentinal Hypersensitivity", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Dentinal Hypersensitivity" ], "interventions": [ { "name": "5% calcium sodium phosphosilicate/ sodium monofluorophosphate dentifrice", "type": "DRUG" }, { "name": "0% calcium sodium phosphosilicate/ sodium monofluorophosphate dentifrice", "type": "DRUG" }, { "name": "Sodium monofluorophosphate dentifrice", "type": "DRUG" }, { "name": "Sodium Fluoride dentifrice", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "GlaxoSmithKline", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "55 Years", "sex": "ALL", "summary": "18 Years to 55 Years" }, "enrollment_count": 140, "start_date": "2013-01", "completion_date": "2013-05", "has_results": true, "last_update_posted_date": "2015-03-26", "last_synced_at": "2026-10-05T05:08:30.350Z", "location_count": 1, "location_summary": "Fort Wayne, Indiana", "locations": [ { "city": "Fort Wayne", "state": "Indiana" } ], "official_url": "https://clinicaltrials.gov/study/NCT01831817" }, { "nct_id": "NCT06373497", "title": "Real-Time Atherosclerosis Activity After Thoracic Radiotherapy Using Sodium Fluoride Positron Emission Tomography", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "EARLY_PHASE1" ], "conditions": [ "Oligometastatic Disease" ], "interventions": [ { "name": "18-F-NaF Cardiac PET/MRI and", "type": "DIAGNOSTIC_TEST" }, { "name": "CT Angiogram", "type": "DIAGNOSTIC_TEST" } ], "intervention_types": [ "DIAGNOSTIC_TEST" ], "sponsor": "Katelyn Atkins", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 10, "start_date": "2025-06-19", "completion_date": "2026-10", "has_results": false, "last_update_posted_date": "2026-08-06", "last_synced_at": "2026-10-05T05:08:30.350Z", "location_count": 1, "location_summary": "Los Angeles, California", "locations": [ { "city": "Los Angeles", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT06373497" }, { "nct_id": "NCT05916508", "title": "A Bleeding-Model Clinical Study", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Gingivitis" ], "interventions": [ { "name": "0.454% stannous fluoride", "type": "DRUG" }, { "name": "0.76% sodium monofluorophosphate", "type": "DRUG" }, { "name": "0.454% stannous fluoride AM and 0.76% sodium monofluorophosphate PM", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Procter and Gamble", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 90, "start_date": "2020-10-19", "completion_date": "2020-11-20", "has_results": false, "last_update_posted_date": "2023-06-23", "last_synced_at": "2026-10-05T05:08:30.350Z", "location_count": 1, "location_summary": "Las Vegas, Nevada", "locations": [ { "city": "Las Vegas", "state": "Nevada" } ], "official_url": "https://clinicaltrials.gov/study/NCT05916508" }, { "nct_id": "NCT00759187", "title": "Evaluate Clinical Research From Commerical Oral Care Products", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Gingival Diseases" ], "interventions": [ { "name": "Fluoride", "type": "DRUG" }, { "name": "Triclosan/Fluoride", "type": "DRUG" }, { "name": "Chlorhexidine Gluconate", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Colgate Palmolive", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "18 Years to 65 Years" }, "enrollment_count": 25, "start_date": "2008-01", "completion_date": "2008-04", "has_results": true, "last_update_posted_date": "2010-03-04", "last_synced_at": "2026-10-05T05:08:30.350Z", "location_count": 1, "location_summary": "Boston, Massachusetts", "locations": [ { "city": "Boston", "state": "Massachusetts" } ], "official_url": "https://clinicaltrials.gov/study/NCT00759187" }, { "nct_id": "NCT03267511", "title": "A Study to Investigate the Stain and Plaque Removal Capability of Two Experimental Potassium Nitrate Dentifrices", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Oral Hygiene" ], "interventions": [ { "name": "5% KNO3 / 0.2542% NaF dentifrice with 0.5% spherical silica", "type": "DRUG" }, { "name": "5% KNO3 / 0.2542% NaF dentifrice with 1% spherical silica and 5% STP", "type": "DRUG" }, { "name": "5% KNO3 / 0.2542% NaF dentifrice with 6% abrasive silica", "type": "DRUG" }, { "name": "5% KNO3 / 0.2543% NaF dentifrice with 16% abrasive silica and 5% STP", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "GlaxoSmithKline", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "18 Years to 65 Years" }, "enrollment_count": 123, "start_date": "2017-09-25", "completion_date": "2017-12-02", "has_results": true, "last_update_posted_date": "2019-01-08", "last_synced_at": "2026-10-05T05:08:30.350Z", "location_count": 1, "location_summary": "Fort Wayne, Indiana", "locations": [ { "city": "Fort Wayne", "state": "Indiana" } ], "official_url": "https://clinicaltrials.gov/study/NCT03267511" }, { "nct_id": "NCT02753075", "title": "A Study in Dentinal Hypersensitivity (DH) Participants to Assess the Efficacy of an Occluding Dentifrice.", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Dentin Sensitivity" ], "interventions": [ { "name": "Experimental Oral Rinse 1", "type": "DEVICE" }, { "name": "Experimental Oral Rinse 2", "type": "DEVICE" }, { "name": "Placebo Oral Rinse", "type": "OTHER" }, { "name": "Fluoride toothpaste", "type": "DRUG" } ], "intervention_types": [ "DEVICE", "OTHER", "DRUG" ], "sponsor": "GlaxoSmithKline", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "55 Years", "sex": "ALL", "summary": "18 Years to 55 Years" }, "enrollment_count": 240, "start_date": "2015-09-08", "completion_date": "2015-12-18", "has_results": true, "last_update_posted_date": "2018-08-27", "last_synced_at": "2026-10-05T05:08:30.350Z", "location_count": 1, "location_summary": "Fort Wayne, Indiana", "locations": [ { "city": "Fort Wayne", "state": "Indiana" } ], "official_url": "https://clinicaltrials.gov/study/NCT02753075" }, { "nct_id": "NCT01650493", "title": "In-situ Evaluation of Anti-caries Technology", "overall_status": "COMPLETED", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Caries" ], "interventions": [ { "name": "Clinpro 5000", "type": "DEVICE" }, { "name": "MI Paste Plus", "type": "DEVICE" }, { "name": "Tom's of Maine", "type": "DEVICE" } ], "intervention_types": [ "DEVICE" ], "sponsor": "Solventum US LLC", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 29, "start_date": "2012-06", "completion_date": "2013-07", "has_results": false, "last_update_posted_date": "2024-10-02", "last_synced_at": "2026-10-05T05:08:30.350Z", "location_count": 1, "location_summary": "Iowa City, Iowa", "locations": [ { "city": "Iowa City", "state": "Iowa" } ], "official_url": "https://clinicaltrials.gov/study/NCT01650493" }, { "nct_id": "NCT07124533", "title": "Effectiveness of Toothpaste Tablets on Plaque, Gingival Health and Caries Experiences", "overall_status": "NOT_YET_RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Gingival Inflammation", "Dental Caries" ], "interventions": [ { "name": "Toothpaste Tablet", "type": "DRUG" }, { "name": "Conventional Toothpaste", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Loma Linda University", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 50, "start_date": "2026-12", "completion_date": "2026-12", "has_results": false, "last_update_posted_date": "2026-07-10", "last_synced_at": "2026-10-05T05:08:30.350Z", "location_count": 2, "location_summary": "Loma Linda, California", "locations": [ { "city": "Loma Linda", "state": "California" }, { "city": "Loma Linda", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT07124533" } ] }