{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Sodium+Fluoride+%280.05%25%29",
    "query": {
      "intervention": "Sodium Fluoride (0.05%)"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 4,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-28T04:49:19.297Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT04239872",
      "title": "Fluoride Retention in the Mouth of Older Adults",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Hyposalivation"
      ],
      "interventions": [
        {
          "name": "Fluoride mouthwash",
          "type": "DRUG"
        },
        {
          "name": "Calcium and fluoride mouthwash",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Michigan",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "65 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "65 Years and older"
      },
      "enrollment_count": 20,
      "start_date": "2020-03-11",
      "completion_date": "2021-04-05",
      "has_results": true,
      "last_update_posted_date": "2023-01-31",
      "last_synced_at": "2026-09-28T04:49:19.297Z",
      "location_count": 1,
      "location_summary": "Ann Arbor, Michigan",
      "locations": [
        {
          "city": "Ann Arbor",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04239872"
    },
    {
      "nct_id": "NCT04620252",
      "title": "Effect of Chewing a Calcium Supplement Before Fluoride Rinse on Salivary Fluoride",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "EARLY_PHASE1"
      ],
      "conditions": [
        "Dental Caries"
      ],
      "interventions": [
        {
          "name": "Inactive supplement",
          "type": "DRUG"
        },
        {
          "name": "Tricalcium phosphate supplement",
          "type": "DRUG"
        },
        {
          "name": "Calcium carbonate supplement",
          "type": "DRUG"
        },
        {
          "name": "Calcium citrate supplement",
          "type": "DRUG"
        },
        {
          "name": "Inactive supplement and fluoride mouthwash",
          "type": "DRUG"
        },
        {
          "name": "Calcium carbonate supplement and fluoride mouthwash",
          "type": "DRUG"
        },
        {
          "name": "Calcium citrate supplement and fluoride mouthwash",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Michigan",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "99 Years",
        "sex": "ALL",
        "summary": "18 Years to 99 Years"
      },
      "enrollment_count": 18,
      "start_date": "2021-02-01",
      "completion_date": "2022-03-31",
      "has_results": false,
      "last_update_posted_date": "2022-05-09",
      "last_synced_at": "2026-09-28T04:49:19.297Z",
      "location_count": 1,
      "location_summary": "Ann Arbor, Michigan",
      "locations": [
        {
          "city": "Ann Arbor",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04620252"
    },
    {
      "nct_id": "NCT02598778",
      "title": "Comparing Mouth Rinses (and Chewing Gum) in Regard to Streptococcus Mutans Reduction",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Dental Caries"
      ],
      "interventions": [
        {
          "name": "Chlorhexidine gluconate (0.12%)",
          "type": "DRUG"
        },
        {
          "name": "Sodium Fluoride (0.05%)",
          "type": "DRUG"
        },
        {
          "name": "Paraffin wax chewing gum (sugar-free)",
          "type": "OTHER"
        },
        {
          "name": "Deionized water",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER"
      ],
      "sponsor": "Montefiore Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "6 Years",
        "maximum_age": "12 Years",
        "sex": "ALL",
        "summary": "6 Years to 12 Years"
      },
      "enrollment_count": 12,
      "start_date": "2015-11-01",
      "completion_date": "2016-04-01",
      "has_results": true,
      "last_update_posted_date": "2022-10-31",
      "last_synced_at": "2026-09-28T04:49:19.297Z",
      "location_count": 1,
      "location_summary": "The Bronx, New York",
      "locations": [
        {
          "city": "The Bronx",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02598778"
    },
    {
      "nct_id": "NCT07829328",
      "title": "Can SAP P11-4 Affect The Appearance of Interproximal Cavities on an X-ray in a Military Population",
      "overall_status": "ENROLLING_BY_INVITATION",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Incipient Interproximal Caries"
      ],
      "interventions": [
        {
          "name": "0.05% Sodium Fluoride with Self-Assembling Peptides",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Tripler Army Medical Center",
      "sponsor_class": "FED",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "74 Years",
        "sex": "ALL",
        "summary": "18 Years to 74 Years"
      },
      "enrollment_count": 30,
      "start_date": "2026-09-30",
      "completion_date": "2027-08",
      "has_results": false,
      "last_update_posted_date": "2026-09-21",
      "last_synced_at": "2026-09-28T04:49:19.297Z",
      "location_count": 1,
      "location_summary": "Schofield Barracks, Hawaii",
      "locations": [
        {
          "city": "Schofield Barracks",
          "state": "Hawaii"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07829328"
    }
  ]
}