{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Sodium+chloride+solution+0.9%25+%28saline%29&page=14",
    "query": {
      "intervention": "Sodium chloride solution 0.9% (saline)",
      "page": 14
    },
    "page_size": 10
  },
  "pagination": {
    "page": 14,
    "page_size": 10,
    "total_count": 752,
    "total_pages": 76,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Sodium+chloride+solution+0.9%25+%28saline%29&page=15&page_size=10",
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Sodium+chloride+solution+0.9%25+%28saline%29&page=13&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-10-14T04:52:23.455Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT01821274",
      "title": "A 21-Day Topical Safety Study of Diltiazem Hydrochloride Using a Cumulative Irritant Patch Test Design",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Skin Irritation"
      ],
      "interventions": [
        {
          "name": "Diltiazem Hydrochloride 2% Cream",
          "type": "DRUG"
        },
        {
          "name": "Vehicle Cream",
          "type": "DRUG"
        },
        {
          "name": "0.1% solution o sodium lauryl sulfate (SLS)",
          "type": "DRUG"
        },
        {
          "name": "Saline 0.9%",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Ventrus Biosciences, Inc",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "18 Years to 75 Years"
      },
      "enrollment_count": 30,
      "start_date": "2013-03",
      "completion_date": "2013-09",
      "has_results": false,
      "last_update_posted_date": "2013-08-21",
      "last_synced_at": "2026-10-14T04:52:23.455Z",
      "location_count": 1,
      "location_summary": "Paramus, New Jersey",
      "locations": [
        {
          "city": "Paramus",
          "state": "New Jersey"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01821274"
    },
    {
      "nct_id": "NCT04512235",
      "title": "A Study to Evaluate the Efficacy and Safety of CAEL-101 in Patients With Mayo Stage IIIa AL Amyloidosis (CARES)",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "AL Amyloidosis"
      ],
      "interventions": [
        {
          "name": "CAEL-101",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "OTHER"
        },
        {
          "name": "cyclophosphamide, bortezomib, and dexamethasone (CyBorD) regimen",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER"
      ],
      "sponsor": "Alexion Pharmaceuticals, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 281,
      "start_date": "2020-11-03",
      "completion_date": "2027-04-08",
      "has_results": true,
      "last_update_posted_date": "2026-06-17",
      "last_synced_at": "2026-10-14T04:52:23.455Z",
      "location_count": 32,
      "location_summary": "Scottsdale, Arizona • Duarte, California • Palo Alto, California + 26 more",
      "locations": [
        {
          "city": "Scottsdale",
          "state": "Arizona"
        },
        {
          "city": "Duarte",
          "state": "California"
        },
        {
          "city": "Palo Alto",
          "state": "California"
        },
        {
          "city": "San Francisco",
          "state": "California"
        },
        {
          "city": "Jacksonville",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04512235"
    },
    {
      "nct_id": "NCT01603459",
      "title": "Efficacy and Safety Dose Titration Study of Botulinum Toxin Type A to Treat Spasticity in the Leg and Arm",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Spasticity of the Upper and Lower Limb Due to Cerebral Causes"
      ],
      "interventions": [
        {
          "name": "IncobotulinumtoxinA",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Merz Pharmaceuticals GmbH",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 155,
      "start_date": "2012-05",
      "completion_date": "2014-09",
      "has_results": true,
      "last_update_posted_date": "2017-04-26",
      "last_synced_at": "2026-10-14T04:52:23.455Z",
      "location_count": 6,
      "location_summary": "Doral, Florida • Indianapolis, Indiana • New York, New York + 3 more",
      "locations": [
        {
          "city": "Doral",
          "state": "Florida"
        },
        {
          "city": "Indianapolis",
          "state": "Indiana"
        },
        {
          "city": "New York",
          "state": "New York"
        },
        {
          "city": "Charlotte",
          "state": "North Carolina"
        },
        {
          "city": "Cleveland",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01603459"
    },
    {
      "nct_id": "NCT02338843",
      "title": "A Phase 3 Study of LJPC-501 in Patients With Catecholamine-Resistant Hypotension",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Catecholamine-resistant Hypotension (CRH)",
        "Distributive Shock",
        "High Output Shock",
        "Sepsis"
      ],
      "interventions": [
        {
          "name": "LJPC-501",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "La Jolla Pharmaceutical Company",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 344,
      "start_date": "2015-03",
      "completion_date": "2017-02-18",
      "has_results": true,
      "last_update_posted_date": "2018-03-27",
      "last_synced_at": "2026-10-14T04:52:23.455Z",
      "location_count": 52,
      "location_summary": "Mobile, Alabama • Phoenix, Arizona • Loma Linda, California + 39 more",
      "locations": [
        {
          "city": "Mobile",
          "state": "Alabama"
        },
        {
          "city": "Phoenix",
          "state": "Arizona"
        },
        {
          "city": "Loma Linda",
          "state": "California"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02338843"
    },
    {
      "nct_id": "NCT02614040",
      "title": "Saline Against Lactated Ringers or Plasmalyte in the Emergency Department",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Critical Illness",
        "Acute Kidney Injury"
      ],
      "interventions": [
        {
          "name": "0.9% Saline",
          "type": "OTHER"
        },
        {
          "name": "Physiologically-balanced isotonic crystalloid",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Vanderbilt University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 14000,
      "start_date": "2016-01-01",
      "completion_date": "2017-06-30",
      "has_results": false,
      "last_update_posted_date": "2017-09-15",
      "last_synced_at": "2026-10-14T04:52:23.455Z",
      "location_count": 1,
      "location_summary": "Nashville, Tennessee",
      "locations": [
        {
          "city": "Nashville",
          "state": "Tennessee"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02614040"
    },
    {
      "nct_id": "NCT02134925",
      "title": "Vaccine Therapy in Treating Patients With Newly Diagnosed Advanced Colon Polyps",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Colorectal Adenoma",
        "Colorectal Carcinoma",
        "Colorectal Conventional Adenoma With Severe Dysplasia",
        "Colorectal Tubulovillous Adenoma"
      ],
      "interventions": [
        {
          "name": "Laboratory Biomarker Analysis",
          "type": "OTHER"
        },
        {
          "name": "MUC1 Peptide-Poly-ICLC Vaccine",
          "type": "BIOLOGICAL"
        },
        {
          "name": "Quality-of-Life Assessment",
          "type": "OTHER"
        },
        {
          "name": "Saline",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER",
        "BIOLOGICAL"
      ],
      "sponsor": "National Cancer Institute (NCI)",
      "sponsor_class": "NIH",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "40 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "40 Years to 70 Years"
      },
      "enrollment_count": 110,
      "start_date": "2014-06-23",
      "completion_date": "2027-03-09",
      "has_results": true,
      "last_update_posted_date": "2026-09-11",
      "last_synced_at": "2026-10-14T04:52:23.455Z",
      "location_count": 6,
      "location_summary": "Boston, Massachusetts • Rochester, Minnesota • Kansas City, Missouri + 2 more",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "Rochester",
          "state": "Minnesota"
        },
        {
          "city": "Kansas City",
          "state": "Missouri"
        },
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        },
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02134925"
    },
    {
      "nct_id": "NCT02726620",
      "title": "Decision Support for Intraoperative Low Blood Pressure",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Hypotension"
      ],
      "interventions": [
        {
          "name": "Attending real-time decision support",
          "type": "PROCEDURE"
        },
        {
          "name": "In-room real-time decision support",
          "type": "PROCEDURE"
        },
        {
          "name": "Attending feedback emails",
          "type": "PROCEDURE"
        },
        {
          "name": "In-room provider feedback emails",
          "type": "PROCEDURE"
        },
        {
          "name": "Anesthesia Information Management System (AIMS)",
          "type": "DEVICE"
        },
        {
          "name": "Perioperative Data Warehouse (PDW)",
          "type": "DEVICE"
        },
        {
          "name": "General anesthesia",
          "type": "PROCEDURE"
        },
        {
          "name": "Pager system",
          "type": "DEVICE"
        },
        {
          "name": "Central neuraxial anesthesia",
          "type": "PROCEDURE"
        },
        {
          "name": "Non-cardiac surgery",
          "type": "PROCEDURE"
        },
        {
          "name": "Propofol",
          "type": "DRUG"
        },
        {
          "name": "Sevoflurane",
          "type": "DRUG"
        },
        {
          "name": "Desflurane",
          "type": "DRUG"
        },
        {
          "name": "Isoflurane",
          "type": "DRUG"
        },
        {
          "name": "Ephedrine",
          "type": "DRUG"
        },
        {
          "name": "Phenylephrine",
          "type": "DRUG"
        },
        {
          "name": "Norepinephrine",
          "type": "DRUG"
        },
        {
          "name": "Epinephrine",
          "type": "DRUG"
        },
        {
          "name": "Dobutamine",
          "type": "DRUG"
        },
        {
          "name": "Dopamine",
          "type": "DRUG"
        },
        {
          "name": "Isoproterenol",
          "type": "DRUG"
        },
        {
          "name": "Milrinone",
          "type": "DRUG"
        },
        {
          "name": "Atropine",
          "type": "DRUG"
        },
        {
          "name": "Glycopyrrolate",
          "type": "DRUG"
        },
        {
          "name": "Vasopressin",
          "type": "DRUG"
        },
        {
          "name": "Terlipressin",
          "type": "DRUG"
        },
        {
          "name": "Sodium Chloride 0.9%",
          "type": "DRUG"
        },
        {
          "name": "Ringer's lactate",
          "type": "DRUG"
        },
        {
          "name": "Hydroxyethyl starch solutions",
          "type": "DRUG"
        },
        {
          "name": "Fresh Frozen Plasma",
          "type": "DRUG"
        },
        {
          "name": "Packed Red Blood Cells",
          "type": "DRUG"
        },
        {
          "name": "Albumin solutions",
          "type": "DRUG"
        },
        {
          "name": "Plasma-Lyte",
          "type": "DRUG"
        },
        {
          "name": "Lidocaine",
          "type": "DRUG"
        },
        {
          "name": "Bupivacaine",
          "type": "DRUG"
        },
        {
          "name": "Levobupivacaine",
          "type": "DRUG"
        },
        {
          "name": "Ropivacaine",
          "type": "DRUG"
        },
        {
          "name": "Mepivacaine",
          "type": "DRUG"
        },
        {
          "name": "Tetracaine",
          "type": "DRUG"
        },
        {
          "name": "Prilocaine",
          "type": "DRUG"
        },
        {
          "name": "Procaine",
          "type": "DRUG"
        },
        {
          "name": "Chloroprocaine",
          "type": "DRUG"
        },
        {
          "name": "Benzocaine",
          "type": "DRUG"
        },
        {
          "name": "Articaine",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "PROCEDURE",
        "DEVICE",
        "DRUG"
      ],
      "sponsor": "Vanderbilt University Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "60 Years",
        "maximum_age": "100 Years",
        "sex": "ALL",
        "summary": "60 Years to 100 Years"
      },
      "enrollment_count": 22435,
      "start_date": "2017-01-05",
      "completion_date": "2018-12-29",
      "has_results": true,
      "last_update_posted_date": "2019-05-16",
      "last_synced_at": "2026-10-14T04:52:23.455Z",
      "location_count": 1,
      "location_summary": "Nashville, Tennessee",
      "locations": [
        {
          "city": "Nashville",
          "state": "Tennessee"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02726620"
    },
    {
      "nct_id": "NCT01531803",
      "title": "Safety Study of Kedbumin 25% Versus Normal Saline in the Treatment of Post-Surgical Hypovolemia in Pediatric Patients",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Hypovolemia"
      ],
      "interventions": [
        {
          "name": "Kedbumin 25%",
          "type": "DRUG"
        },
        {
          "name": "Normal Saline Solution",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Kedrion S.p.A.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "12 Years",
        "sex": "ALL",
        "summary": "Up to 12 Years"
      },
      "enrollment_count": 3,
      "start_date": "2015-02-05",
      "completion_date": "2015-07-15",
      "has_results": true,
      "last_update_posted_date": "2023-11-15",
      "last_synced_at": "2026-10-14T04:52:23.455Z",
      "location_count": 2,
      "location_summary": "Louisville, Kentucky • Milwaukee, Wisconsin",
      "locations": [
        {
          "city": "Louisville",
          "state": "Kentucky"
        },
        {
          "city": "Milwaukee",
          "state": "Wisconsin"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01531803"
    },
    {
      "nct_id": "NCT00801931",
      "title": "Double Cord Blood Transplant for Patients With Malignant and Non-malignant Disorders",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1",
        "PHASE2"
      ],
      "conditions": [
        "Leukemia",
        "Lymphoma",
        "Neuroblastoma",
        "Immunodeficiencies",
        "Anemia"
      ],
      "interventions": [
        {
          "name": "Alemtuzumab",
          "type": "DRUG"
        },
        {
          "name": "Total Body Irradiation",
          "type": "RADIATION"
        },
        {
          "name": "Melphalan",
          "type": "DRUG"
        },
        {
          "name": "Busulfan",
          "type": "DRUG"
        },
        {
          "name": "Phenytoin",
          "type": "DRUG"
        },
        {
          "name": "Fludarabine",
          "type": "DRUG"
        },
        {
          "name": "Cyclophosphamide",
          "type": "DRUG"
        },
        {
          "name": "Horse Antithymocyte Globulin",
          "type": "DRUG"
        },
        {
          "name": "Rabbit Antithymocyte Globulin",
          "type": "DRUG"
        },
        {
          "name": "Thiotepa",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG",
        "RADIATION"
      ],
      "sponsor": "Columbia University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "30 Years",
        "sex": "ALL",
        "summary": "Up to 30 Years"
      },
      "enrollment_count": 1,
      "start_date": "2007-09-06",
      "completion_date": "2009-05-05",
      "has_results": true,
      "last_update_posted_date": "2019-03-27",
      "last_synced_at": "2026-10-14T04:52:23.455Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00801931"
    },
    {
      "nct_id": "NCT06327113",
      "title": "Antibiotic Tumescent For Chronic Wounds",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Non-healing Wound"
      ],
      "interventions": [
        {
          "name": "CeFAZolin Injectable Solution",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of California, Los Angeles",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 60,
      "start_date": "2024-05-17",
      "completion_date": "2028-05-25",
      "has_results": false,
      "last_update_posted_date": "2026-04-23",
      "last_synced_at": "2026-10-14T04:52:23.455Z",
      "location_count": 1,
      "location_summary": "Los Angeles, California",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06327113"
    }
  ]
}