{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Soothe",
    "query": {
      "intervention": "Soothe"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 23,
    "total_pages": 3,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Soothe&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-03T11:45:27.121Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT01013077",
      "title": "The Effect of a New Emulsion in Dry Eye Patients on Tear Layer Aberrometry, Contrast Sensitivity, and Reading Ability",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Dry Eye Syndrome"
      ],
      "interventions": [
        {
          "name": "Optive, Soothe, New Emulsion",
          "type": "OTHER"
        },
        {
          "name": "Soothe, New Emulsion, Optive",
          "type": "OTHER"
        },
        {
          "name": "New Emulsion, Optive, Soothe",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Southern California College of Optometry at Marshall B. Ketchum University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 20,
      "start_date": "2009-11",
      "completion_date": "2011-08",
      "has_results": true,
      "last_update_posted_date": "2025-06-12",
      "last_synced_at": "2026-09-03T11:45:27.121Z",
      "location_count": 1,
      "location_summary": "Fullerton, California",
      "locations": [
        {
          "city": "Fullerton",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01013077"
    },
    {
      "nct_id": "NCT03533985",
      "title": "Effect of Music Therapy on Infants With Neonatal Abstinence Syndrome",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "NAS"
      ],
      "interventions": [
        {
          "name": "Song of Kin",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Gato box",
          "type": "OTHER"
        },
        {
          "name": "Ocean disc",
          "type": "OTHER"
        },
        {
          "name": "Contingent singing",
          "type": "OTHER"
        },
        {
          "name": "Tonal Vocal holding",
          "type": "OTHER"
        },
        {
          "name": "Muted shaker",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL",
        "OTHER"
      ],
      "sponsor": "Icahn School of Medicine at Mount Sinai",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "28 Weeks",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "28 Weeks and older"
      },
      "enrollment_count": 200,
      "start_date": "2017-11-01",
      "completion_date": "2026-12-31",
      "has_results": false,
      "last_update_posted_date": "2026-07-22",
      "last_synced_at": "2026-09-03T11:45:27.121Z",
      "location_count": 6,
      "location_summary": "New Orleans, Louisiana • Hackensack, New Jersey • New Hyde Park, New York + 3 more",
      "locations": [
        {
          "city": "New Orleans",
          "state": "Louisiana"
        },
        {
          "city": "Hackensack",
          "state": "New Jersey"
        },
        {
          "city": "New Hyde Park",
          "state": "New York"
        },
        {
          "city": "New York",
          "state": "New York"
        },
        {
          "city": "Valhalla",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03533985"
    },
    {
      "nct_id": "NCT03505203",
      "title": "Sleep-Safe: A Strong African American Families Study",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Weight Gain"
      ],
      "interventions": [
        {
          "name": "Sleep Soothe",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Sleep Safe",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Georgia",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "17 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "17 Years and older"
      },
      "enrollment_count": 234,
      "start_date": "2018-03-04",
      "completion_date": "2021-07-05",
      "has_results": false,
      "last_update_posted_date": "2025-02-06",
      "last_synced_at": "2026-09-03T11:45:27.121Z",
      "location_count": 1,
      "location_summary": "Athens, Georgia",
      "locations": [
        {
          "city": "Athens",
          "state": "Georgia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03505203"
    },
    {
      "nct_id": "NCT00791323",
      "title": "Efficacy of Ketorolac 0.4% in Prostaglandin Suppression",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Inflammation"
      ],
      "interventions": [
        {
          "name": "Ketorolac 0.4%",
          "type": "DRUG"
        },
        {
          "name": "Lubricating Eye Drop",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Allergan",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 9,
      "start_date": "2008-11",
      "completion_date": "2009-08",
      "has_results": true,
      "last_update_posted_date": "2011-09-23",
      "last_synced_at": "2026-09-03T11:45:27.121Z",
      "location_count": 1,
      "location_summary": "Houston, Texas",
      "locations": [
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00791323"
    },
    {
      "nct_id": "NCT04825210",
      "title": "Integrated Behavioral Health Prevention in Pediatric Primary Care for Infants",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Prevention"
      ],
      "interventions": [
        {
          "name": "Integrated Behavioral Health - Prevention",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Bright Futures: Guidelines for Health Supervision of Infants, Children, and Adolescents, 4th Edition",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Children's Hospital Medical Center, Cincinnati",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "55 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 55 Years · Female only"
      },
      "enrollment_count": 160,
      "start_date": "2021-04-13",
      "completion_date": "2022-08-24",
      "has_results": false,
      "last_update_posted_date": "2022-09-13",
      "last_synced_at": "2026-09-03T11:45:27.121Z",
      "location_count": 1,
      "location_summary": "Cincinnati, Ohio",
      "locations": [
        {
          "city": "Cincinnati",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04825210"
    },
    {
      "nct_id": "NCT02120079",
      "title": "The Utility of IVCM to Assess Cellular Response and Efficacy of Long-term Topical Steroid Treatment in Patients With DED",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Dry Eye Disease"
      ],
      "interventions": [
        {
          "name": "Lotemax",
          "type": "DRUG"
        },
        {
          "name": "Soothe Tired Eyes Lubricant Eye Drop (Artificial Tears)",
          "type": "DRUG"
        },
        {
          "name": "In Vivo Confocal Microscopy (IVCM)",
          "type": "DIAGNOSTIC_TEST"
        }
      ],
      "intervention_types": [
        "DRUG",
        "DIAGNOSTIC_TEST"
      ],
      "sponsor": "Tufts Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "89 Years",
        "sex": "ALL",
        "summary": "18 Years to 89 Years"
      },
      "enrollment_count": 37,
      "start_date": "2014-02",
      "completion_date": "2018-01-28",
      "has_results": true,
      "last_update_posted_date": "2024-06-26",
      "last_synced_at": "2026-09-03T11:45:27.121Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02120079"
    },
    {
      "nct_id": "NCT05078112",
      "title": "Sleep Device Testing to Promote Sleep in Infants",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Insomnia Chronic"
      ],
      "interventions": [
        {
          "name": "Sleep sensor technology",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Duke University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "2 Months",
        "maximum_age": "12 Months",
        "sex": "ALL",
        "summary": "2 Months to 12 Months"
      },
      "enrollment_count": 19,
      "start_date": "2021-10-20",
      "completion_date": "2022-07-31",
      "has_results": true,
      "last_update_posted_date": "2024-10-15",
      "last_synced_at": "2026-09-03T11:45:27.121Z",
      "location_count": 1,
      "location_summary": "Durham, North Carolina",
      "locations": [
        {
          "city": "Durham",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05078112"
    },
    {
      "nct_id": "NCT03888820",
      "title": "Biofreeze® vs. a Placebo on Chronic Low Back Pain Walking Gait Characteristics and Pain",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Chronic Low Back Pain"
      ],
      "interventions": [
        {
          "name": "Biofreeze",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Sport and Spine Rehab Clinical Research Foundation",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 20,
      "start_date": "2018-03-01",
      "completion_date": "2019-04-30",
      "has_results": false,
      "last_update_posted_date": "2019-03-25",
      "last_synced_at": "2026-09-03T11:45:27.121Z",
      "location_count": 1,
      "location_summary": "Rockville, Maryland",
      "locations": [
        {
          "city": "Rockville",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03888820"
    },
    {
      "nct_id": "NCT03157349",
      "title": "Effect of Biofreeze® Versus Placebo on Acute Neck Pain, Disability, and Range of Motion",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Acute Pain",
        "Neck Pain"
      ],
      "interventions": [
        {
          "name": "Biofreeze",
          "type": "OTHER"
        },
        {
          "name": "Placebo",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Sport and Spine Rehab Clinical Research Foundation",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 59,
      "start_date": "2017-03-01",
      "completion_date": "2019-02-01",
      "has_results": false,
      "last_update_posted_date": "2019-11-01",
      "last_synced_at": "2026-09-03T11:45:27.121Z",
      "location_count": 1,
      "location_summary": "Landover, Maryland",
      "locations": [
        {
          "city": "Landover",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03157349"
    },
    {
      "nct_id": "NCT00284999",
      "title": "Soothe Versus Refresh",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Dry Eye Syndromes"
      ],
      "interventions": [
        {
          "name": "Soothe",
          "type": "DRUG"
        },
        {
          "name": "Refresh Tears",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Pharmaceutical Research Network",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 33,
      "start_date": null,
      "completion_date": "2006-08",
      "has_results": false,
      "last_update_posted_date": "2006-08-22",
      "last_synced_at": "2026-09-03T11:45:27.121Z",
      "location_count": 3,
      "location_summary": "Atlanta, Georgia • Southfield, Michigan • New York, New York",
      "locations": [
        {
          "city": "Atlanta",
          "state": "Georgia"
        },
        {
          "city": "Southfield",
          "state": "Michigan"
        },
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00284999"
    }
  ]
}