{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Spice+blend",
    "query": {
      "intervention": "Spice blend"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 9,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-03T18:37:51.398Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT03513536",
      "title": "The Effect of Scent on Pregnancy Induced Nausea, Vomiting, and Quality of Life",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Morning Sickness",
        "Pregnancy Early"
      ],
      "interventions": [
        {
          "name": "Citrus-Based Aromatherapy",
          "type": "OTHER"
        },
        {
          "name": "Mint-Based Aromatherapy",
          "type": "OTHER"
        },
        {
          "name": "Spice-Scented Aromatherapy",
          "type": "OTHER"
        },
        {
          "name": "Control",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Nutraceuticals Research Institute",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "45 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 45 Years · Female only"
      },
      "enrollment_count": 74,
      "start_date": "2018-04-15",
      "completion_date": "2020-03-29",
      "has_results": false,
      "last_update_posted_date": "2020-04-29",
      "last_synced_at": "2026-09-03T18:37:51.398Z",
      "location_count": 1,
      "location_summary": "Franklin, Tennessee",
      "locations": [
        {
          "city": "Franklin",
          "state": "Tennessee"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03513536"
    },
    {
      "nct_id": "NCT00954902",
      "title": "Effects of Antioxidants on Cardiovascular Risk Measures (Spice Study)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Cardiovascular",
        "Psychological Stress"
      ],
      "interventions": [
        {
          "name": "High Antioxidant Spice Blend",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Trier Psychological Stressor",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Placebo antioxidant concentrate",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT",
        "BEHAVIORAL",
        "OTHER"
      ],
      "sponsor": "Penn State University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "30 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "30 Years to 65 Years"
      },
      "enrollment_count": 32,
      "start_date": "2009-08",
      "completion_date": "2010-09",
      "has_results": false,
      "last_update_posted_date": "2018-01-25",
      "last_synced_at": "2026-09-03T18:37:51.398Z",
      "location_count": 1,
      "location_summary": "University Park, Pennsylvania",
      "locations": [
        {
          "city": "University Park",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00954902"
    },
    {
      "nct_id": "NCT03063320",
      "title": "The Effect of Spice Consumption on Postprandial Vascular Function",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Cardiovascular Risk Factor"
      ],
      "interventions": [
        {
          "name": "Spice blend",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Penn State University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "30 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "30 Years to 75 Years"
      },
      "enrollment_count": 43,
      "start_date": "2017-01-25",
      "completion_date": "2020-02-26",
      "has_results": false,
      "last_update_posted_date": "2023-09-18",
      "last_synced_at": "2026-09-03T18:37:51.398Z",
      "location_count": 1,
      "location_summary": "University Park, Pennsylvania",
      "locations": [
        {
          "city": "University Park",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03063320"
    },
    {
      "nct_id": "NCT02522559",
      "title": "Using Herbs and Spices to Increase Children's Acceptance and Intake of Vegetables in School Lunches",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Pediatric Obesity"
      ],
      "interventions": [
        {
          "name": "Spice Intervention",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Penn State University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "11 Years",
        "maximum_age": "19 Years",
        "sex": "ALL",
        "summary": "11 Years to 19 Years"
      },
      "enrollment_count": 110,
      "start_date": "2015-04-14",
      "completion_date": "2017-12-22",
      "has_results": false,
      "last_update_posted_date": "2018-01-05",
      "last_synced_at": "2026-09-03T18:37:51.398Z",
      "location_count": 1,
      "location_summary": "Wingate, Pennsylvania",
      "locations": [
        {
          "city": "Wingate",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02522559"
    },
    {
      "nct_id": "NCT04020419",
      "title": "Natural Berry Extract Treatment of Hemangiomas",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "EARLY_PHASE1"
      ],
      "conditions": [
        "Hemangioma"
      ],
      "interventions": [
        {
          "name": "PediaBerry",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Gayle Gordillo",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "1 Month",
        "maximum_age": "19 Weeks",
        "sex": "ALL",
        "summary": "1 Month to 19 Weeks"
      },
      "enrollment_count": 12,
      "start_date": "2020-12-01",
      "completion_date": "2023-05-24",
      "has_results": false,
      "last_update_posted_date": "2023-10-23",
      "last_synced_at": "2026-09-03T18:37:51.398Z",
      "location_count": 2,
      "location_summary": "Indianapolis, Indiana • Columbus, Ohio",
      "locations": [
        {
          "city": "Indianapolis",
          "state": "Indiana"
        },
        {
          "city": "Columbus",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04020419"
    },
    {
      "nct_id": "NCT07254624",
      "title": "Pilot Assessment of Continuous Glucose Monitor for Post-meal Glucose Responses to Herbs and Spices.",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Post-prandial Glucose Response"
      ],
      "interventions": [
        {
          "name": "Mix of five herbs and spices",
          "type": "OTHER"
        },
        {
          "name": "Potato entree",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Alabama at Birmingham",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "50 Years",
        "sex": "ALL",
        "summary": "18 Years to 50 Years"
      },
      "enrollment_count": 10,
      "start_date": "2026-03-16",
      "completion_date": "2027-11",
      "has_results": false,
      "last_update_posted_date": "2026-06-09",
      "last_synced_at": "2026-09-03T18:37:51.398Z",
      "location_count": 1,
      "location_summary": "Birmingham, Alabama",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07254624"
    },
    {
      "nct_id": "NCT03043118",
      "title": "Children's Taste Study to Increase Vegetable Intake in Preschoolers",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Pediatric Obesity"
      ],
      "interventions": [
        {
          "name": "Variety Intervention",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Penn State University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "3 Years",
        "maximum_age": "5 Years",
        "sex": "ALL",
        "summary": "3 Years to 5 Years"
      },
      "enrollment_count": 48,
      "start_date": "2015-02",
      "completion_date": "2016-11-02",
      "has_results": false,
      "last_update_posted_date": "2022-04-05",
      "last_synced_at": "2026-09-03T18:37:51.398Z",
      "location_count": 1,
      "location_summary": "University Park, Pennsylvania",
      "locations": [
        {
          "city": "University Park",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03043118"
    },
    {
      "nct_id": "NCT05055362",
      "title": "Effect a Honey, Spice-blended Baked Good Has on Salivary Inflammation Markers in Adults: a Pilot Study",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Chronic Kidney Diseases",
        "Overweight and Obesity"
      ],
      "interventions": [
        {
          "name": "Honey Spice Group",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Florida",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 15,
      "start_date": "2021-09-22",
      "completion_date": "2022-03-04",
      "has_results": false,
      "last_update_posted_date": "2024-06-10",
      "last_synced_at": "2026-09-03T18:37:51.398Z",
      "location_count": 1,
      "location_summary": "Gainesville, Florida",
      "locations": [
        {
          "city": "Gainesville",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05055362"
    },
    {
      "nct_id": "NCT03064932",
      "title": "Effect of a Spice Blend on Cardiovascular Risk Factors and Diet Satisfaction",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Cardiovascular Disease",
        "Inflammation"
      ],
      "interventions": [
        {
          "name": "Controlled feeding diet",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Penn State University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "30 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "30 Years to 75 Years"
      },
      "enrollment_count": 71,
      "start_date": "2017-01-25",
      "completion_date": "2020-02-26",
      "has_results": false,
      "last_update_posted_date": "2023-08-18",
      "last_synced_at": "2026-09-03T18:37:51.398Z",
      "location_count": 1,
      "location_summary": "University Park, Pennsylvania",
      "locations": [
        {
          "city": "University Park",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03064932"
    }
  ]
}