{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Spontaneous+Breathing",
    "query": {
      "intervention": "Spontaneous Breathing"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 74,
    "total_pages": 8,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Spontaneous+Breathing&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-12T10:16:56.638Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT02202031",
      "title": "Controlling Urgency Through Relaxation Exercises",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Overactive Bladder",
        "Urgency Urinary Symptoms",
        "Urgency Incontinence"
      ],
      "interventions": [
        {
          "name": "Paced Respiration",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Music Therapy",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of California, San Francisco",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "21 Years and older · Female only"
      },
      "enrollment_count": 161,
      "start_date": "2014-09",
      "completion_date": "2018-03",
      "has_results": true,
      "last_update_posted_date": "2019-07-30",
      "last_synced_at": "2026-09-12T10:16:56.638Z",
      "location_count": 1,
      "location_summary": "San Francisco, California",
      "locations": [
        {
          "city": "San Francisco",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02202031"
    },
    {
      "nct_id": "NCT01746576",
      "title": "Use of Near Infrared Spectroscopy to Measure Intracranial ScvO2",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Healthy"
      ],
      "interventions": [
        {
          "name": "Use of impedance threshold device during spontaneous ventilation",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Virginia",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 20,
      "start_date": "2012-09",
      "completion_date": "2013-09",
      "has_results": false,
      "last_update_posted_date": "2014-04-16",
      "last_synced_at": "2026-09-12T10:16:56.638Z",
      "location_count": 1,
      "location_summary": "Charlottesville, Virginia",
      "locations": [
        {
          "city": "Charlottesville",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01746576"
    },
    {
      "nct_id": "NCT03955874",
      "title": "Mechanical Ventilation Discontinuation Practices",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Invasive Mechanical Ventilation",
        "Critical Illness",
        "Spontaneous Breathing Trial",
        "Weaning Invasive Mechanical Ventilation",
        "Tracheostomy",
        "Direct Extubation"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Unity Health Toronto",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "16 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "16 Years and older"
      },
      "enrollment_count": 1868,
      "start_date": "2013-11-04",
      "completion_date": "2016-12-17",
      "has_results": false,
      "last_update_posted_date": "2021-04-02",
      "last_synced_at": "2026-09-12T10:16:56.638Z",
      "location_count": 2,
      "location_summary": "Boston, Massachusetts • Ann Arbor, Michigan",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "Ann Arbor",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03955874"
    },
    {
      "nct_id": "NCT02399267",
      "title": "Frequency of Screening and SBT Technique Trial",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Critically Ill"
      ],
      "interventions": [
        {
          "name": "Once daily screening",
          "type": "PROCEDURE"
        },
        {
          "name": "Twice daily screening",
          "type": "PROCEDURE"
        },
        {
          "name": "PS SBTs",
          "type": "PROCEDURE"
        },
        {
          "name": "T-piece SBTs",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Unity Health Toronto",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "16 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "16 Years and older"
      },
      "enrollment_count": 100,
      "start_date": "2016-07",
      "completion_date": "2021-12",
      "has_results": false,
      "last_update_posted_date": "2019-04-04",
      "last_synced_at": "2026-09-12T10:16:56.638Z",
      "location_count": 2,
      "location_summary": "Long Beach, California • Atlanta, Georgia",
      "locations": [
        {
          "city": "Long Beach",
          "state": "California"
        },
        {
          "city": "Atlanta",
          "state": "Georgia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02399267"
    },
    {
      "nct_id": "NCT01901354",
      "title": "Acute Lung Injury Ventilator Evaluation (ALIVE)",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Acute Lung Injury",
        "Adult Respiratory Distress Syndrome"
      ],
      "interventions": [
        {
          "name": "Low-tidal-volume ventilation",
          "type": "OTHER"
        },
        {
          "name": "Airway Pressure Release Ventilation (APRV)",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Wisconsin, Madison",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 4,
      "start_date": "2013-11",
      "completion_date": "2014-10",
      "has_results": false,
      "last_update_posted_date": "2017-09-28",
      "last_synced_at": "2026-09-12T10:16:56.638Z",
      "location_count": 1,
      "location_summary": "Madison, Wisconsin",
      "locations": [
        {
          "city": "Madison",
          "state": "Wisconsin"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01901354"
    },
    {
      "nct_id": "NCT00891085",
      "title": "Synchronized Intermittent Mechanical Ventilation Versus Open Lung Ventilation With Spontaneous Respiration",
      "overall_status": "TERMINATED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Trauma"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "University of New Mexico",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 5,
      "start_date": "2007-10",
      "completion_date": "2008-01",
      "has_results": false,
      "last_update_posted_date": "2023-05-19",
      "last_synced_at": "2026-09-12T10:16:56.638Z",
      "location_count": 1,
      "location_summary": "Albuquerque, New Mexico",
      "locations": [
        {
          "city": "Albuquerque",
          "state": "New Mexico"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00891085"
    },
    {
      "nct_id": "NCT02969226",
      "title": "The Frequency of Screening and SBT Technique Trial: The FAST Trial",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Critically Ill"
      ],
      "interventions": [
        {
          "name": "Once daily screening",
          "type": "PROCEDURE"
        },
        {
          "name": "Twice daily screening",
          "type": "PROCEDURE"
        },
        {
          "name": "PS SBTs",
          "type": "PROCEDURE"
        },
        {
          "name": "T-piece SBTs",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Unity Health Toronto",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "16 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "16 Years and older"
      },
      "enrollment_count": 760,
      "start_date": "2018-01-18",
      "completion_date": "2021-03",
      "has_results": false,
      "last_update_posted_date": "2018-12-05",
      "last_synced_at": "2026-09-12T10:16:56.638Z",
      "location_count": 5,
      "location_summary": "Long Beach, California • Los Angeles, California • Boston, Massachusetts + 2 more",
      "locations": [
        {
          "city": "Long Beach",
          "state": "California"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "Ann Arbor",
          "state": "Michigan"
        },
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02969226"
    },
    {
      "nct_id": "NCT01541462",
      "title": "Weaning From Prolonged Mechanical Ventilation",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Acute Mechanical Ventilatory Failure"
      ],
      "interventions": [
        {
          "name": "Weaning",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "RML Specialty Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 500,
      "start_date": "2000-10",
      "completion_date": "2011-10",
      "has_results": false,
      "last_update_posted_date": "2012-03-01",
      "last_synced_at": "2026-09-12T10:16:56.638Z",
      "location_count": 1,
      "location_summary": "Hinsdale, Illinois",
      "locations": [
        {
          "city": "Hinsdale",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01541462"
    },
    {
      "nct_id": "NCT04458324",
      "title": "Hybrid Functional Electrical Stimulation Exercise to Prevent Cardiopulmonary Declines in High-level Spinal Cord Injury",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Spinal Cord Injuries"
      ],
      "interventions": [
        {
          "name": "Buspirone Hydrochloride",
          "type": "DRUG"
        },
        {
          "name": "Buspirone placebo",
          "type": "DRUG"
        },
        {
          "name": "Noninvasive Ventilation (NIV)",
          "type": "DEVICE"
        },
        {
          "name": "Sham Non-invasive ventilation (NIV)",
          "type": "DEVICE"
        },
        {
          "name": "Functional Electrical Stimulation Row Training (FESRT)",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "DEVICE",
        "OTHER"
      ],
      "sponsor": "Spaulding Rehabilitation Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "55 Years",
        "sex": "ALL",
        "summary": "18 Years to 55 Years"
      },
      "enrollment_count": 70,
      "start_date": "2020-12-22",
      "completion_date": "2027-07-31",
      "has_results": false,
      "last_update_posted_date": "2026-03-05",
      "last_synced_at": "2026-09-12T10:16:56.638Z",
      "location_count": 1,
      "location_summary": "Cambridge, Massachusetts",
      "locations": [
        {
          "city": "Cambridge",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04458324"
    },
    {
      "nct_id": "NCT03267212",
      "title": "Acute Effect of Ventilatory Support During Exercise in Spinal Cord Injury",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Spinal Cord Injury"
      ],
      "interventions": [
        {
          "name": "Non-invasive ventilation(NIV)",
          "type": "DEVICE"
        },
        {
          "name": "Sham Non-invasive ventilation(NIV)",
          "type": "DEVICE"
        },
        {
          "name": "Functional Electrical Stimulation Row Training (FESRT)",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "OTHER"
      ],
      "sponsor": "Spaulding Rehabilitation Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "18 Years to 70 Years"
      },
      "enrollment_count": 15,
      "start_date": "2017-07-14",
      "completion_date": "2019-04-01",
      "has_results": true,
      "last_update_posted_date": "2020-04-09",
      "last_synced_at": "2026-09-12T10:16:56.638Z",
      "location_count": 1,
      "location_summary": "Cambridge, Massachusetts",
      "locations": [
        {
          "city": "Cambridge",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03267212"
    }
  ]
}