{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Standard+PVI&page=2",
    "query": {
      "intervention": "Standard PVI",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 10,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Standard+PVI&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-09-18T18:23:43.002Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT01959997",
      "title": "Comparison of Redo PVI With vs. Without Renal Denervation for Recurrent AF After Initial PVI",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Atrial Fibrillation",
        "Arterial Hypertension"
      ],
      "interventions": [
        {
          "name": "Redo PVI",
          "type": "PROCEDURE"
        },
        {
          "name": "PVI + RDN",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Meshalkin Research Institute of Pathology of Circulation",
      "sponsor_class": "NETWORK",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "18 Years to 75 Years"
      },
      "enrollment_count": 60,
      "start_date": "2013-09",
      "completion_date": "2016-09",
      "has_results": false,
      "last_update_posted_date": "2015-09-23",
      "last_synced_at": "2026-09-18T18:23:43.002Z",
      "location_count": 1,
      "location_summary": "Rochester, New York",
      "locations": [
        {
          "city": "Rochester",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01959997"
    },
    {
      "nct_id": "NCT07041125",
      "title": "Concomitant LAAC/AF Ablation (Watchman FLX Pro)",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "PFA Ablation and LAAC Procedures"
      ],
      "interventions": [
        {
          "name": "Watchman FLX™ Pro device.",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Heart Rhythm Clinical and Research Solutions, LLC",
      "sponsor_class": "OTHER",
      "healthy_volunteers": null,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 122,
      "start_date": "2025-06-01",
      "completion_date": "2026-06-30",
      "has_results": false,
      "last_update_posted_date": "2026-08-31",
      "last_synced_at": "2026-09-18T18:23:43.002Z",
      "location_count": 15,
      "location_summary": "Birmingham, Alabama • San Francisco, California • Littleton, Colorado + 12 more",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "San Francisco",
          "state": "California"
        },
        {
          "city": "Littleton",
          "state": "Colorado"
        },
        {
          "city": "Delray Beach",
          "state": "Florida"
        },
        {
          "city": "Jacksonville",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07041125"
    },
    {
      "nct_id": "NCT07541989",
      "title": "Pulsed-Field Ablation With/Without Electrogram Mapping",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Non-paroxysmal Atrial Fibrillation"
      ],
      "interventions": [
        {
          "name": "PFA-based PVI+PWI plus adjunctive ablation guided by Electrogram Mapping of Key Substrates",
          "type": "PROCEDURE"
        },
        {
          "name": "PFA-based PVI+PWI alone",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Xu Liu",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 300,
      "start_date": "2024-09-30",
      "completion_date": "2028-06-01",
      "has_results": false,
      "last_update_posted_date": "2026-04-21",
      "last_synced_at": "2026-09-18T18:23:43.002Z",
      "location_count": 1,
      "location_summary": "The Bronx, New York",
      "locations": [
        {
          "city": "The Bronx",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07541989"
    },
    {
      "nct_id": "NCT02918396",
      "title": "The Substrate and Intervention Mechanisms for Persistent Atrial Fibrillation Trial",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Persistent Atrial Fibrillation"
      ],
      "interventions": [
        {
          "name": "Scar-Based Radio-frequency Ablation",
          "type": "DEVICE"
        },
        {
          "name": "Rotor Anchors Radio-frequency Ablation",
          "type": "DEVICE"
        },
        {
          "name": "Conventional PVI by Radio-frequency Ablation",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Johns Hopkins University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 5,
      "start_date": "2016-04",
      "completion_date": "2017-10",
      "has_results": true,
      "last_update_posted_date": "2018-01-04",
      "last_synced_at": "2026-09-18T18:23:43.002Z",
      "location_count": 1,
      "location_summary": "Baltimore, Maryland",
      "locations": [
        {
          "city": "Baltimore",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02918396"
    },
    {
      "nct_id": "NCT05116384",
      "title": "Renal Denervation + PVI vs PVI Alone for Persistent AF",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Atrial Fibrillation"
      ],
      "interventions": [
        {
          "name": "catheter ablation",
          "type": "DEVICE"
        },
        {
          "name": "renal artery denervation",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of Rochester",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 50,
      "start_date": "2023-07-30",
      "completion_date": "2026-06-30",
      "has_results": false,
      "last_update_posted_date": "2025-12-11",
      "last_synced_at": "2026-09-18T18:23:43.002Z",
      "location_count": 1,
      "location_summary": "Short Hills, New Jersey",
      "locations": [
        {
          "city": "Short Hills",
          "state": "New Jersey"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05116384"
    },
    {
      "nct_id": "NCT02758002",
      "title": "Inhibition of Atrial Fibrillation by Elimination of Transitional Mechanisms",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Atrial Fibrillation",
        "Arrhythmia"
      ],
      "interventions": [
        {
          "name": "Firm ablation for transitional AF rotors",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "University of California, San Diego",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "21 Years to 80 Years"
      },
      "enrollment_count": 0,
      "start_date": "2016-01-28",
      "completion_date": "2018-12",
      "has_results": false,
      "last_update_posted_date": "2020-02-28",
      "last_synced_at": "2026-09-18T18:23:43.002Z",
      "location_count": 1,
      "location_summary": "La Jolla, California",
      "locations": [
        {
          "city": "La Jolla",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02758002"
    },
    {
      "nct_id": "NCT05481359",
      "title": "AF-FLOW Registry to Evaluate Electrographic Flow Mapping in Patients Undergoing Ablation for Atrial Fibrillation",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Atrial Fibrillation, Persistent",
        "Atrial Fibrillation",
        "Arrhythmias, Cardiac",
        "Heart Diseases"
      ],
      "interventions": [
        {
          "name": "Electrographic Flow™ (EGF) mapping and ablation",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Ablacon, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 25,
      "start_date": "2022-09-12",
      "completion_date": "2023-11-17",
      "has_results": true,
      "last_update_posted_date": "2025-04-10",
      "last_synced_at": "2026-09-18T18:23:43.002Z",
      "location_count": 3,
      "location_summary": "Athens, Georgia • Atlanta, Georgia • New York, New York",
      "locations": [
        {
          "city": "Athens",
          "state": "Georgia"
        },
        {
          "city": "Atlanta",
          "state": "Georgia"
        },
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05481359"
    },
    {
      "nct_id": "NCT02841397",
      "title": "Validation of Noninvasive Hemoglobin, Comparison of PVI to Standard Methods, and Validation of Clinical Efficacy of ORI",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [],
      "conditions": [
        "Surgery"
      ],
      "interventions": [
        {
          "name": "Masimo Pulse CO-Oximeter",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Masimo Corporation",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 50,
      "start_date": "2017-03-09",
      "completion_date": "2017-10-11",
      "has_results": true,
      "last_update_posted_date": "2021-10-21",
      "last_synced_at": "2026-09-18T18:23:43.002Z",
      "location_count": 1,
      "location_summary": "Loma Linda, California",
      "locations": [
        {
          "city": "Loma Linda",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02841397"
    },
    {
      "nct_id": "NCT01873352",
      "title": "Renal Artery Denervation In Addition to Catheter Ablation To Eliminate Atrial Fibrillation",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Atrial Fibrillation",
        "Hypertension"
      ],
      "interventions": [
        {
          "name": "catheter ablation",
          "type": "PROCEDURE"
        },
        {
          "name": "renal sympathetic denervation",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Meshalkin Research Institute of Pathology of Circulation",
      "sponsor_class": "NETWORK",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "18 Years to 75 Years"
      },
      "enrollment_count": 302,
      "start_date": "2013-06-20",
      "completion_date": "2019-03-01",
      "has_results": false,
      "last_update_posted_date": "2019-09-04",
      "last_synced_at": "2026-09-18T18:23:43.002Z",
      "location_count": 1,
      "location_summary": "Short Hills, New Jersey",
      "locations": [
        {
          "city": "Short Hills",
          "state": "New Jersey"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01873352"
    },
    {
      "nct_id": "NCT01877473",
      "title": "Comparison of Reverse Remodeling and PVI Versus CFAE and/or Linear Lesions and PVI for Persistent AF",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Persistent Atrial Fibrillation"
      ],
      "interventions": [
        {
          "name": "Ablation",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Valley Health System",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "85 Years",
        "sex": "ALL",
        "summary": "18 Years to 85 Years"
      },
      "enrollment_count": 0,
      "start_date": "2013-05",
      "completion_date": "2013-09",
      "has_results": false,
      "last_update_posted_date": "2014-06-17",
      "last_synced_at": "2026-09-18T18:23:43.002Z",
      "location_count": 1,
      "location_summary": "Ridgewood, New Jersey",
      "locations": [
        {
          "city": "Ridgewood",
          "state": "New Jersey"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01877473"
    }
  ]
}