{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Standard+disease-directed+therapy&page=2",
    "query": {
      "intervention": "Standard disease-directed therapy",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 120,
    "total_pages": 12,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Standard+disease-directed+therapy&page=3&page_size=10",
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Standard+disease-directed+therapy&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-09-30T10:24:24.013Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT07444216",
      "title": "A Longitudinal Photo-Narrative Exploration of Hope During Phase 1/2 Clinical Trials For Pediatric Cancer",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Cancer, Therapy-Related"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "St. Jude Children's Research Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": null,
      "eligibility": {
        "minimum_age": "12 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "12 Years and older"
      },
      "enrollment_count": 100,
      "start_date": "2026-04-09",
      "completion_date": "2030-03",
      "has_results": false,
      "last_update_posted_date": "2026-04-28",
      "last_synced_at": "2026-09-30T10:24:24.013Z",
      "location_count": 1,
      "location_summary": "Memphis, Tennessee",
      "locations": [
        {
          "city": "Memphis",
          "state": "Tennessee"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07444216"
    },
    {
      "nct_id": "NCT04560946",
      "title": "Personalized, Augmented Cognitive Training (PACT) for Service Members and Veterans with a History of TBI",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Traumatic Brain Injury"
      ],
      "interventions": [
        {
          "name": "Personalized Augmented Cognitive Training (PACT)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Enhanced Treatment As Usual",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Veterans Medical Research Foundation",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "55 Years",
        "sex": "ALL",
        "summary": "18 Years to 55 Years"
      },
      "enrollment_count": 107,
      "start_date": "2019-09-30",
      "completion_date": "2023-09-30",
      "has_results": false,
      "last_update_posted_date": "2024-11-21",
      "last_synced_at": "2026-09-30T10:24:24.013Z",
      "location_count": 2,
      "location_summary": "San Diego, California",
      "locations": [
        {
          "city": "San Diego",
          "state": "California"
        },
        {
          "city": "San Diego",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04560946"
    },
    {
      "nct_id": "NCT05178472",
      "title": "Vertebroplasty With Radiation Therapy for Spine Metastatic Cancer Patients With Indeterminate Lesion (SINS Criteria)",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Hematopoietic and Lymphoid Cell Neoplasm",
        "Malignant Solid Neoplasm",
        "Metastatic Malignant Neoplasm in the Spine"
      ],
      "interventions": [
        {
          "name": "Immunotherapy",
          "type": "OTHER"
        },
        {
          "name": "Stereotactic Radiosurgery",
          "type": "RADIATION"
        },
        {
          "name": "Vertebroplasty",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "OTHER",
        "RADIATION",
        "PROCEDURE"
      ],
      "sponsor": "Ohio State University Comprehensive Cancer Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 200,
      "start_date": "2023-03-27",
      "completion_date": "2026-12-31",
      "has_results": false,
      "last_update_posted_date": "2026-04-09",
      "last_synced_at": "2026-09-30T10:24:24.013Z",
      "location_count": 1,
      "location_summary": "Columbus, Ohio",
      "locations": [
        {
          "city": "Columbus",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05178472"
    },
    {
      "nct_id": "NCT02541032",
      "title": "PeRiodontal Treatment to Eliminate Minority InEquality and Rural Disparities in Stroke",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Periodontal Disease",
        "Stroke",
        "TIA"
      ],
      "interventions": [
        {
          "name": "Intensive dental treatment",
          "type": "PROCEDURE"
        },
        {
          "name": "Standard dental treatment",
          "type": "PROCEDURE"
        },
        {
          "name": "Arestin",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "PROCEDURE",
        "DRUG"
      ],
      "sponsor": "University of South Carolina",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 400,
      "start_date": "2015-12",
      "completion_date": "2020-06",
      "has_results": false,
      "last_update_posted_date": "2019-04-18",
      "last_synced_at": "2026-09-30T10:24:24.013Z",
      "location_count": 2,
      "location_summary": "Chapel Hill, North Carolina • Columbia, South Carolina",
      "locations": [
        {
          "city": "Chapel Hill",
          "state": "North Carolina"
        },
        {
          "city": "Columbia",
          "state": "South Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02541032"
    },
    {
      "nct_id": "NCT07148180",
      "title": "A Multi-Site Break Through Cancer Trial: Targeting Measurable Residual Disease in Patients With Acute Myeloid Leukemia: A Phase 1/2 Study of Tagraxofusp, Azacitidine, and Venetoclax",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1",
        "PHASE2"
      ],
      "conditions": [
        "Acute Myeloid Leukaemia (AML)",
        "Leukemia",
        "Blood Cancer",
        "Blood Cancers"
      ],
      "interventions": [
        {
          "name": "Tagraxofusp",
          "type": "DRUG"
        },
        {
          "name": "Azacitidine (AZA)",
          "type": "DRUG"
        },
        {
          "name": "Venetoclax",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Jacqueline Garcia, MD",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 31,
      "start_date": "2026-02-02",
      "completion_date": "2030-12-31",
      "has_results": false,
      "last_update_posted_date": "2026-02-05",
      "last_synced_at": "2026-09-30T10:24:24.013Z",
      "location_count": 2,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07148180"
    },
    {
      "nct_id": "NCT06040463",
      "title": "Improving Diabetes Equity and Advancing Care Study",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Diabetes",
        "Diabetes Mellitus",
        "Diabetes Mellitus, Type 1",
        "Diabetes Mellitus, Type 2"
      ],
      "interventions": [
        {
          "name": "Diabetes Self-Management Training (DSMT)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Remote Glucose Monitoring (RGM)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Community Health Worker tailored support",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Sinai Health System",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 270,
      "start_date": "2023-10-23",
      "completion_date": "2025-03-31",
      "has_results": false,
      "last_update_posted_date": "2023-12-07",
      "last_synced_at": "2026-09-30T10:24:24.013Z",
      "location_count": 1,
      "location_summary": "Chicago, Illinois",
      "locations": [
        {
          "city": "Chicago",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06040463"
    },
    {
      "nct_id": "NCT04856891",
      "title": "A Study of Lirentelimab (AK002) in Patients With Active Eosinophilic Duodenitis",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Eosinophilic Duodenitis",
        "Eosinophilic Gastroenteritis"
      ],
      "interventions": [
        {
          "name": "AK002",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER"
      ],
      "sponsor": "Allakos Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 94,
      "start_date": "2021-05-20",
      "completion_date": "2023-01-09",
      "has_results": true,
      "last_update_posted_date": "2024-01-02",
      "last_synced_at": "2026-09-30T10:24:24.013Z",
      "location_count": 39,
      "location_summary": "Birmingham, Alabama • Gilbert, Arizona • Chula Vista, California + 35 more",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        },
        {
          "city": "Gilbert",
          "state": "Arizona"
        },
        {
          "city": "Chula Vista",
          "state": "California"
        },
        {
          "city": "Lomita",
          "state": "California"
        },
        {
          "city": "Wheat Ridge",
          "state": "Colorado"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04856891"
    },
    {
      "nct_id": "NCT07211724",
      "title": "Methamphetamine Use Disorder Support in Heart Failure Pilot Study",
      "overall_status": "NOT_YET_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Heart Failure",
        "Methamphetamine Use Disorder"
      ],
      "interventions": [
        {
          "name": "MUD Management (contingency management +/- adjunctive MUD pharmacotherapy)",
          "type": "OTHER"
        },
        {
          "name": "HF GDMT management",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Southern California",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 50,
      "start_date": "2026-05-31",
      "completion_date": "2027-07",
      "has_results": false,
      "last_update_posted_date": "2026-05-04",
      "last_synced_at": "2026-09-30T10:24:24.013Z",
      "location_count": 2,
      "location_summary": "Los Angeles, California",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07211724"
    },
    {
      "nct_id": "NCT04278560",
      "title": "Modulating Brain Activity to Improve Goal-directed Physical Activity in Older Adults",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Aging"
      ],
      "interventions": [
        {
          "name": "Transcranial direct current stimulation (tDCS)",
          "type": "DEVICE"
        },
        {
          "name": "Sham stimulation",
          "type": "DEVICE"
        },
        {
          "name": "Behavioral intervention to increase physical activity",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "BEHAVIORAL"
      ],
      "sponsor": "Hebrew SeniorLife",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "65 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "65 Years and older"
      },
      "enrollment_count": 34,
      "start_date": "2020-02-12",
      "completion_date": "2022-11-03",
      "has_results": true,
      "last_update_posted_date": "2024-05-16",
      "last_synced_at": "2026-09-30T10:24:24.013Z",
      "location_count": 1,
      "location_summary": "Roslindale, Massachusetts",
      "locations": [
        {
          "city": "Roslindale",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04278560"
    },
    {
      "nct_id": "NCT04787744",
      "title": "Veterans Affairs Seamless Phase II/III Randomized Trial of STAndard Systemic theRapy With or Without PET-directed Local Therapy for Oligometastatic pRosTate Cancer",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2",
        "PHASE3"
      ],
      "conditions": [
        "Prostate Cancer",
        "Oligometastasis",
        "Oligorecurrence",
        "Recurrent Prostate Cancer",
        "Metastatic Prostate Cancer",
        "De Novo Prostate Cancer"
      ],
      "interventions": [
        {
          "name": "PET-directed Local Therapy using Surgery",
          "type": "PROCEDURE"
        },
        {
          "name": "PET-directed Local Therapy using Radiation",
          "type": "RADIATION"
        },
        {
          "name": "Salvage Local Therapy for locally recurrent disease",
          "type": "OTHER"
        },
        {
          "name": "Goserelin, Histrelin, Leuprolide & Triptorelin",
          "type": "DRUG"
        },
        {
          "name": "ADT + Nilutamide, Flutamide, & Bicalutamide",
          "type": "DRUG"
        },
        {
          "name": "Degarelix & Relugolix",
          "type": "DRUG"
        },
        {
          "name": "ADT + Docetaxel +/- prednisone",
          "type": "DRUG"
        },
        {
          "name": "ADT + Abiraterone + Prednisone",
          "type": "DRUG"
        },
        {
          "name": "ADT + Abiraterone + Methylprednisolone",
          "type": "DRUG"
        },
        {
          "name": "ADT + Apalutamide",
          "type": "DRUG"
        },
        {
          "name": "ADT + Enzalutamide",
          "type": "DRUG"
        },
        {
          "name": "Prostate-directed Radiation for De novo oligometastatic prostate cancer",
          "type": "RADIATION"
        }
      ],
      "intervention_types": [
        "PROCEDURE",
        "RADIATION",
        "OTHER",
        "DRUG"
      ],
      "sponsor": "VA Office of Research and Development",
      "sponsor_class": "FED",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "MALE",
        "summary": "18 Years and older · Male only"
      },
      "enrollment_count": 464,
      "start_date": "2021-07-01",
      "completion_date": "2029-03-30",
      "has_results": false,
      "last_update_posted_date": "2026-04-08",
      "last_synced_at": "2026-09-30T10:24:24.013Z",
      "location_count": 20,
      "location_summary": "Long Beach, California • West Los Angeles, California • Washington D.C., District of Columbia + 17 more",
      "locations": [
        {
          "city": "Long Beach",
          "state": "California"
        },
        {
          "city": "West Los Angeles",
          "state": "California"
        },
        {
          "city": "Washington D.C.",
          "state": "District of Columbia"
        },
        {
          "city": "Bay Pines",
          "state": "Florida"
        },
        {
          "city": "Hines",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04787744"
    }
  ]
}