{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Standard+of+Care+%28Reference%29",
    "query": {
      "intervention": "Standard of Care (Reference)"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 110,
    "total_pages": 11,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Standard+of+Care+%28Reference%29&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-13T10:11:27.582Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT02608879",
      "title": "Oral Care Protocol for the Management of Chemotherapy and Radiation Therapy-Induced Oral Mucositis",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Oral Mucositis",
        "Oral Cancer"
      ],
      "interventions": [
        {
          "name": "Oral Mucosa Deterging and Periodontal Debridement (OMDP)",
          "type": "PROCEDURE"
        },
        {
          "name": "Standard of Care Oral Hygiene Instructions",
          "type": "PROCEDURE"
        },
        {
          "name": "Dental scaling, ultrasonic",
          "type": "PROCEDURE"
        },
        {
          "name": "Chlorhexidine",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "PROCEDURE",
        "OTHER"
      ],
      "sponsor": "NYU Langone Health",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 19,
      "start_date": "2014-03",
      "completion_date": "2015-09",
      "has_results": true,
      "last_update_posted_date": "2020-08-28",
      "last_synced_at": "2026-09-13T10:11:27.582Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02608879"
    },
    {
      "nct_id": "NCT04488913",
      "title": "Rapid Acute Coronary Syndrome Exclusion Using High-sensitivity I Troponin",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Chest Pain",
        "Myocardial Ischemia"
      ],
      "interventions": [
        {
          "name": "RACE-IT Pathway",
          "type": "OTHER"
        },
        {
          "name": "Standard of Care",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Henry Ford Health System",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 32609,
      "start_date": "2020-07-29",
      "completion_date": "2022-03-03",
      "has_results": false,
      "last_update_posted_date": "2022-03-23",
      "last_synced_at": "2026-09-13T10:11:27.582Z",
      "location_count": 1,
      "location_summary": "Detroit, Michigan",
      "locations": [
        {
          "city": "Detroit",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04488913"
    },
    {
      "nct_id": "NCT07623902",
      "title": "Evaluation of Gixam's Efficacy Predicting the Presence of Advanced and Non-advanced Colorectal Neoplasia in a FIT Negative Population",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "CRC Screening",
        "Microbiome"
      ],
      "interventions": [
        {
          "name": "Gixam System",
          "type": "DEVICE"
        },
        {
          "name": "FIT",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Standard of care screening colonoscopy",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "DIAGNOSTIC_TEST",
        "PROCEDURE"
      ],
      "sponsor": "Jubaan Ltd.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "45 Years",
        "maximum_age": "84 Years",
        "sex": "ALL",
        "summary": "45 Years to 84 Years"
      },
      "enrollment_count": 1436,
      "start_date": "2026-05-18",
      "completion_date": "2026-12-31",
      "has_results": false,
      "last_update_posted_date": "2026-06-03",
      "last_synced_at": "2026-09-13T10:11:27.582Z",
      "location_count": 5,
      "location_summary": "Orlando, Florida • Northbrook, Illinois • Carmel, New York + 2 more",
      "locations": [
        {
          "city": "Orlando",
          "state": "Florida"
        },
        {
          "city": "Northbrook",
          "state": "Illinois"
        },
        {
          "city": "Carmel",
          "state": "New York"
        },
        {
          "city": "Mentor",
          "state": "Ohio"
        },
        {
          "city": "Lynchburg",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07623902"
    },
    {
      "nct_id": "NCT06675695",
      "title": "Emulation of the FLAURA (NCT02296125) Trial Using Specialty Oncology Electronic Health Records Databases",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Non Small Cell Lung Cancer"
      ],
      "interventions": [
        {
          "name": "New use of osimertinib",
          "type": "DRUG"
        },
        {
          "name": "New use of erlotinib or gefitinib",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Brigham and Women's Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 4864,
      "start_date": "2024-10-30",
      "completion_date": "2025-11-01",
      "has_results": false,
      "last_update_posted_date": "2026-01-30",
      "last_synced_at": "2026-09-13T10:11:27.582Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06675695"
    },
    {
      "nct_id": "NCT03302741",
      "title": "Imaging of 3D Innervation Zone Distribution in Spastic Muscles From High-density Surface EMG Recordings",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Spasticity"
      ],
      "interventions": [
        {
          "name": "Botulinum neurotoxin (BTX)",
          "type": "DRUG"
        },
        {
          "name": "Physical Therapy",
          "type": "OTHER"
        },
        {
          "name": "Standard BTX injection (ultrasound guided)",
          "type": "DEVICE"
        },
        {
          "name": "3-dimensional innervation zone (3DIZ) guided injection",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER",
        "DEVICE"
      ],
      "sponsor": "The University of Texas Health Science Center, Houston",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "21 Years to 75 Years"
      },
      "enrollment_count": 17,
      "start_date": "2017-11-21",
      "completion_date": "2019-11-18",
      "has_results": true,
      "last_update_posted_date": "2020-11-05",
      "last_synced_at": "2026-09-13T10:11:27.582Z",
      "location_count": 1,
      "location_summary": "Houston, Texas",
      "locations": [
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03302741"
    },
    {
      "nct_id": "NCT03304587",
      "title": "Effects of Bright Light on Co-occurring Cancer-related Symptoms in Breast Cancer Survivors",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Breast Cancer"
      ],
      "interventions": [
        {
          "name": "Polysomnography (PSG)",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Rectal thermistor 400 Series",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Bright blue-green light",
          "type": "OTHER"
        },
        {
          "name": "Dim red light",
          "type": "OTHER"
        },
        {
          "name": "Digital foot candle datalogging light meter",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Patient-Reported Outcomes Measurement Information System (PROMIS)-Cancer-Fatigue",
          "type": "OTHER"
        },
        {
          "name": "Patient-Reported Outcomes Measurement Information System (PROMIS)-Sleep Disturbance",
          "type": "OTHER"
        },
        {
          "name": "Patient-Reported Outcomes Measurement Information System (PROMIS)-Depression",
          "type": "OTHER"
        },
        {
          "name": "Patient-Reported Outcomes Measurement Information System (PROMIS)-Physical Function",
          "type": "OTHER"
        },
        {
          "name": "Pittsburgh Sleep Quality Index (PSQI)",
          "type": "OTHER"
        },
        {
          "name": "Center for Epidemiological Studies - Depression",
          "type": "OTHER"
        },
        {
          "name": "Montreal Cognitive Assessment (MoCA)",
          "type": "OTHER"
        },
        {
          "name": "European Organization for Research and Treatment of Cancer-Quality of Life Questionnaire (EORTC QLQ-C30)",
          "type": "OTHER"
        },
        {
          "name": "Daily Log",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DIAGNOSTIC_TEST",
        "OTHER"
      ],
      "sponsor": "Michigan State University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "21 Years and older · Female only"
      },
      "enrollment_count": 30,
      "start_date": "2017-11-06",
      "completion_date": "2022-08-31",
      "has_results": true,
      "last_update_posted_date": "2025-06-10",
      "last_synced_at": "2026-09-13T10:11:27.582Z",
      "location_count": 1,
      "location_summary": "East Lansing, Michigan",
      "locations": [
        {
          "city": "East Lansing",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03304587"
    },
    {
      "nct_id": "NCT01715168",
      "title": "A Crossover Bioequivalence Study of Intravenously Administered ATI0918 and DOXIL/CAELYX in Patients With Ovarian Cancer",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Ovarian Cancer",
        "Malignant Female Reproductive System Neoplasm",
        "Cancer",
        "Ovarian Tumor",
        "Ovarian Epithelial Cancer Recurrent"
      ],
      "interventions": [
        {
          "name": "DOXIL/CAELYX",
          "type": "DRUG"
        },
        {
          "name": "ATI-0918",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Azaya Therapeutics, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "70 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 70 Years · Female only"
      },
      "enrollment_count": 40,
      "start_date": "2012-10",
      "completion_date": "2015-12",
      "has_results": false,
      "last_update_posted_date": "2015-01-15",
      "last_synced_at": "2026-09-13T10:11:27.582Z",
      "location_count": 1,
      "location_summary": "Yakima, Washington",
      "locations": [
        {
          "city": "Yakima",
          "state": "Washington"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01715168"
    },
    {
      "nct_id": "NCT04199117",
      "title": "Health Systems Reach Interventions Project",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Smoking, Cigarette",
        "Smoking Cessation"
      ],
      "interventions": [
        {
          "name": "Varenicline",
          "type": "DRUG"
        },
        {
          "name": "Combination nicotine patch and nicotine mini-lozenge treatment",
          "type": "DRUG"
        },
        {
          "name": "Monetary incentives for initiating treatment",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Automated tailored outreach",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Care management",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Wisconsin Tobacco Quit Line referral",
          "type": "OTHER"
        },
        {
          "name": "Primary care provider referral",
          "type": "OTHER"
        },
        {
          "name": "Untailored outreach",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Multiple smoking cessation coaching calls",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "DRUG",
        "BEHAVIORAL",
        "OTHER"
      ],
      "sponsor": "University of Wisconsin, Madison",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 210,
      "start_date": "2020-03-11",
      "completion_date": "2024-10-16",
      "has_results": true,
      "last_update_posted_date": "2025-09-24",
      "last_synced_at": "2026-09-13T10:11:27.582Z",
      "location_count": 1,
      "location_summary": "Madison, Wisconsin",
      "locations": [
        {
          "city": "Madison",
          "state": "Wisconsin"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04199117"
    },
    {
      "nct_id": "NCT03214640",
      "title": "Rivanna Ultrasound for Neuraxial Block",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Analgesia"
      ],
      "interventions": [
        {
          "name": "Rivanna Accuro US Device",
          "type": "DEVICE"
        },
        {
          "name": "Palpation",
          "type": "OTHER"
        },
        {
          "name": "Neuraxial Analgesia",
          "type": "PROCEDURE"
        },
        {
          "name": "Spinal Block",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "OTHER",
        "PROCEDURE"
      ],
      "sponsor": "Wake Forest University Health Sciences",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "50 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 50 Years · Female only"
      },
      "enrollment_count": 128,
      "start_date": "2017-10-23",
      "completion_date": "2019-04-13",
      "has_results": true,
      "last_update_posted_date": "2021-07-28",
      "last_synced_at": "2026-09-13T10:11:27.582Z",
      "location_count": 1,
      "location_summary": "Winston-Salem, North Carolina",
      "locations": [
        {
          "city": "Winston-Salem",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03214640"
    },
    {
      "nct_id": "NCT07800962",
      "title": "Federated Learning for Point-of-Care Cardiac Ultrasound",
      "overall_status": "ENROLLING_BY_INVITATION",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Ventricular Dysfunction, Left",
        "Ventricular Function, Left",
        "Echocardiography",
        "Ultrasonography",
        "Point-of-Care Systems",
        "Heart Function Tests",
        "Stroke Volume",
        "Federated Learning",
        "Machine Learning",
        "Artificial Intelligence (AI)",
        "Deep Learning",
        "Neural Networks, Computer",
        "Image Interpretation, Computer-Assisted",
        "Diagnosis, Computer-Assisted",
        "Sensitivity and Specificity",
        "ROC Curve"
      ],
      "interventions": [
        {
          "name": "Focused Cardiac Point-of-Care Ultrasonography",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "FL-POCUS Federated Machine-Learning Analysis System",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DIAGNOSTIC_TEST",
        "DEVICE"
      ],
      "sponsor": "Truway Health, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 3000,
      "start_date": "2026-08-31",
      "completion_date": "2037-09-30",
      "has_results": false,
      "last_update_posted_date": "2026-09-02",
      "last_synced_at": "2026-09-13T10:11:27.582Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07800962"
    }
  ]
}