{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Standard+of+Care+-+Observation+Only&page=2",
    "query": {
      "intervention": "Standard of Care - Observation Only",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 120,
    "total_pages": 12,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Standard+of+Care+-+Observation+Only&page=3&page_size=10",
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Standard+of+Care+-+Observation+Only&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-10-01T04:13:20.768Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT05440851",
      "title": "Platform of Randomized Adaptive Clinical Trials in Critical Illness",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Respiratory Insufficiency",
        "Extracorporeal Membrane Oxygenation Complication",
        "Mechanical Ventilation Pressure High"
      ],
      "interventions": [
        {
          "name": "Ultra-Protective Ventilation Facilitated by Extracorporeal Support",
          "type": "OTHER"
        },
        {
          "name": "Lung-Protective Ventilation (LPV)",
          "type": "OTHER"
        },
        {
          "name": "Driving Pressure-Limited Ventilation (DPL)",
          "type": "OTHER"
        },
        {
          "name": "Lung- and Diaphragm-Protective Ventilation and Sedation (LDPVS)",
          "type": "OTHER"
        },
        {
          "name": "Early Cohort corticosteroid dose",
          "type": "DRUG"
        },
        {
          "name": "Extended Cohort corticosteroid dose",
          "type": "DRUG"
        },
        {
          "name": "Usual care without routine corticosteroids",
          "type": "DRUG"
        },
        {
          "name": "Usual care without extending corticosteroids",
          "type": "DRUG"
        },
        {
          "name": "Usual care with fludrocortisone",
          "type": "DRUG"
        },
        {
          "name": "Usual care without fludrocortisone",
          "type": "DRUG"
        },
        {
          "name": "Drug 4 mL:",
          "type": "DRUG"
        },
        {
          "name": "Drug 40 mg:",
          "type": "DRUG"
        },
        {
          "name": "PEEP-20",
          "type": "OTHER"
        },
        {
          "name": "PEEP-AOP",
          "type": "OTHER"
        },
        {
          "name": "PEEP-10",
          "type": "OTHER"
        },
        {
          "name": "VV ECMO-facilitated strategy of earlier awakening, extubation and rehabilitation",
          "type": "OTHER"
        },
        {
          "name": "Electrical impedance tomography (EIT)",
          "type": "OTHER"
        },
        {
          "name": "no treatment / intervention arm is involved.",
          "type": "OTHER"
        },
        {
          "name": "Usual care",
          "type": "OTHER"
        },
        {
          "name": "Early Routine IMT",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER",
        "DRUG"
      ],
      "sponsor": "University Health Network, Toronto",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 6250,
      "start_date": "2023-04-30",
      "completion_date": "2027-03-31",
      "has_results": false,
      "last_update_posted_date": "2026-05-07",
      "last_synced_at": "2026-10-01T04:13:20.768Z",
      "location_count": 26,
      "location_summary": "Tucson, Arizona • Los Angeles, California • San Diego, California + 19 more",
      "locations": [
        {
          "city": "Tucson",
          "state": "Arizona"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "San Diego",
          "state": "California"
        },
        {
          "city": "San Francisco",
          "state": "California"
        },
        {
          "city": "Aurora",
          "state": "Colorado"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05440851"
    },
    {
      "nct_id": "NCT05012878",
      "title": "Cardiac Rehab and Cerebral Blood Flow Study",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Cardiovascular Diseases"
      ],
      "interventions": [
        {
          "name": "Cardiac rehabilitation - high intensity interval training (HIIT)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Cardiac rehabilitation - moderate intensity continuous training (MICT)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Cardiac rehabilitation - control",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Cardiac rehabilitation - observational",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Mayo Clinic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "40 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "40 Years and older"
      },
      "enrollment_count": 45,
      "start_date": "2021-09-02",
      "completion_date": "2025-04-23",
      "has_results": false,
      "last_update_posted_date": "2025-05-29",
      "last_synced_at": "2026-10-01T04:13:20.768Z",
      "location_count": 1,
      "location_summary": "Rochester, Minnesota",
      "locations": [
        {
          "city": "Rochester",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05012878"
    },
    {
      "nct_id": "NCT07427407",
      "title": "Prospective Ultrasound Data Collection Study for AI-Based Detection of Breast Biopsy Markers",
      "overall_status": "NOT_YET_RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Breast Cancer"
      ],
      "interventions": [
        {
          "name": "Breast Ultrasound Imaging With Investigational AI Software",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "AURA Health Technologies",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "21 Years and older · Female only"
      },
      "enrollment_count": 100,
      "start_date": "2026-05",
      "completion_date": "2027-12",
      "has_results": false,
      "last_update_posted_date": "2026-02-24",
      "last_synced_at": "2026-10-01T04:13:20.768Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07427407"
    },
    {
      "nct_id": "NCT06872775",
      "title": "855303-RNA Biomarker Validation",
      "overall_status": "ENROLLING_BY_INVITATION",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Fractures, Bone"
      ],
      "interventions": [
        {
          "name": "Blood draws to assess RNA expression levels",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Pennsylvania",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 110,
      "start_date": "2025-08-25",
      "completion_date": "2028-08-24",
      "has_results": false,
      "last_update_posted_date": "2026-01-16",
      "last_synced_at": "2026-10-01T04:13:20.768Z",
      "location_count": 7,
      "location_summary": "Sacramento, California • Bloomington, Indiana • Columbia, Missouri + 4 more",
      "locations": [
        {
          "city": "Sacramento",
          "state": "California"
        },
        {
          "city": "Bloomington",
          "state": "Indiana"
        },
        {
          "city": "Columbia",
          "state": "Missouri"
        },
        {
          "city": "Charlotte",
          "state": "North Carolina"
        },
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06872775"
    },
    {
      "nct_id": "NCT06200103",
      "title": "Schedule De-Escalation of 177Lu-PSMA-617 for the Treatment of Metastatic Castrate Resistant Prostate Cancer",
      "overall_status": "SUSPENDED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Castration-Resistant Prostate Carcinoma",
        "Stage IVB Prostate Cancer AJCC v8"
      ],
      "interventions": [
        {
          "name": "Biospecimen Collection",
          "type": "PROCEDURE"
        },
        {
          "name": "Bone Scan",
          "type": "PROCEDURE"
        },
        {
          "name": "Clinical Observation",
          "type": "OTHER"
        },
        {
          "name": "Computed Tomography",
          "type": "PROCEDURE"
        },
        {
          "name": "Gallium Ga 68 Gozetotide",
          "type": "OTHER"
        },
        {
          "name": "Lutetium Lu 177 Vipivotide Tetraxetan",
          "type": "DRUG"
        },
        {
          "name": "Positron Emission Tomography",
          "type": "PROCEDURE"
        },
        {
          "name": "Questionnaire Administration",
          "type": "OTHER"
        },
        {
          "name": "Single Photon Emission Computed Tomography",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE",
        "OTHER",
        "DRUG"
      ],
      "sponsor": "Mayo Clinic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "MALE",
        "summary": "18 Years and older · Male only"
      },
      "enrollment_count": 236,
      "start_date": "2024-05-03",
      "completion_date": "2029-12-31",
      "has_results": false,
      "last_update_posted_date": "2026-08-20",
      "last_synced_at": "2026-10-01T04:13:20.768Z",
      "location_count": 1,
      "location_summary": "Rochester, Minnesota",
      "locations": [
        {
          "city": "Rochester",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06200103"
    },
    {
      "nct_id": "NCT04608617",
      "title": "SYNCHRONISE: LVO Triage Timing and Outcome Study",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Stroke, Ischemic"
      ],
      "interventions": [
        {
          "name": "Viz LVO (De Novo Number DEN170073)",
          "type": "DEVICE"
        },
        {
          "name": "Baseline Effectiveness Cohort",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "OTHER"
      ],
      "sponsor": "Viz.ai, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 600,
      "start_date": "2021-03-09",
      "completion_date": "2023-04-26",
      "has_results": false,
      "last_update_posted_date": "2024-09-19",
      "last_synced_at": "2026-10-01T04:13:20.768Z",
      "location_count": 3,
      "location_summary": "Atlanta, Georgia • Memphis, Tennessee • Harlingen, Texas",
      "locations": [
        {
          "city": "Atlanta",
          "state": "Georgia"
        },
        {
          "city": "Memphis",
          "state": "Tennessee"
        },
        {
          "city": "Harlingen",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04608617"
    },
    {
      "nct_id": "NCT05835024",
      "title": "Acorai Machine Learning Generalization (MLG) Study",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Heart Failure"
      ],
      "interventions": [
        {
          "name": "Acorai Sensor Data Collection (ASDC) system 1.0 - Phase 1",
          "type": "DEVICE"
        },
        {
          "name": "Acorai Sensor Data Collection (ASDC) system 1.0 - Phase 2",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Acorai AB",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 1602,
      "start_date": "2023-08-15",
      "completion_date": "2024-10-31",
      "has_results": false,
      "last_update_posted_date": "2024-12-03",
      "last_synced_at": "2026-10-01T04:13:20.768Z",
      "location_count": 10,
      "location_summary": "Conway, Arkansas • Little Rock, Arkansas • Jacksonville, Florida + 6 more",
      "locations": [
        {
          "city": "Conway",
          "state": "Arkansas"
        },
        {
          "city": "Little Rock",
          "state": "Arkansas"
        },
        {
          "city": "Jacksonville",
          "state": "Florida"
        },
        {
          "city": "Stuart",
          "state": "Florida"
        },
        {
          "city": "Kansas City",
          "state": "Missouri"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05835024"
    },
    {
      "nct_id": "NCT06205511",
      "title": "The Prevalence of Oral HPV Infection and Oral Lesions in People Living With HIV",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Human Immunodeficiency Virus",
        "Human Papilloma Virus"
      ],
      "interventions": [
        {
          "name": "Oral HPV Sample",
          "type": "DIAGNOSTIC_TEST"
        }
      ],
      "intervention_types": [
        "DIAGNOSTIC_TEST"
      ],
      "sponsor": "Vivent Health",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 300,
      "start_date": "2023-04-01",
      "completion_date": "2024-10-01",
      "has_results": false,
      "last_update_posted_date": "2026-08-27",
      "last_synced_at": "2026-10-01T04:13:20.768Z",
      "location_count": 3,
      "location_summary": "Denver, Colorado • St Louis, Missouri • Milwaukee, Wisconsin",
      "locations": [
        {
          "city": "Denver",
          "state": "Colorado"
        },
        {
          "city": "St Louis",
          "state": "Missouri"
        },
        {
          "city": "Milwaukee",
          "state": "Wisconsin"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06205511"
    },
    {
      "nct_id": "NCT04028063",
      "title": "Doxorubicin Plus Dual Checkpoint Blockade for Soft Tissue Sarcomas",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Metastatic Soft Tissue Sarcoma",
        "Advanced Soft Tissue Sarcoma"
      ],
      "interventions": [
        {
          "name": "Balstilimab",
          "type": "DRUG"
        },
        {
          "name": "Zalifrelimab",
          "type": "DRUG"
        },
        {
          "name": "Doxorubicin",
          "type": "DRUG"
        },
        {
          "name": "Botensilimab",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Colorado, Denver",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "100 Years",
        "sex": "ALL",
        "summary": "18 Years to 100 Years"
      },
      "enrollment_count": 65,
      "start_date": "2020-01-28",
      "completion_date": "2027-12-31",
      "has_results": false,
      "last_update_posted_date": "2026-04-20",
      "last_synced_at": "2026-10-01T04:13:20.768Z",
      "location_count": 1,
      "location_summary": "Aurora, Colorado",
      "locations": [
        {
          "city": "Aurora",
          "state": "Colorado"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04028063"
    },
    {
      "nct_id": "NCT03139877",
      "title": "Pediatric Obesity Observational Prospective Trial",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Pediatric Obesity"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Duke University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "10 Years",
        "maximum_age": "18 Years",
        "sex": "ALL",
        "summary": "10 Years to 18 Years"
      },
      "enrollment_count": 295,
      "start_date": "2016-09-13",
      "completion_date": "2020-01-07",
      "has_results": false,
      "last_update_posted_date": "2021-06-18",
      "last_synced_at": "2026-10-01T04:13:20.768Z",
      "location_count": 1,
      "location_summary": "Durham, North Carolina",
      "locations": [
        {
          "city": "Durham",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03139877"
    }
  ]
}