{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Standard+of+Care-VLU",
    "query": {
      "intervention": "Standard of Care-VLU"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 26,
    "total_pages": 3,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Standard+of+Care-VLU&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-14T10:04:49.404Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT03257254",
      "title": "Effect of VarIthena on Wound Healing in Venous Leg Ulcers (VLU)",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Venous Leg Ulcer"
      ],
      "interventions": [
        {
          "name": "Varithena",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Boston Scientific Corporation",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": null,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 76,
      "start_date": "2017-09-29",
      "completion_date": "2020-09-28",
      "has_results": true,
      "last_update_posted_date": "2021-12-14",
      "last_synced_at": "2026-09-14T10:04:49.404Z",
      "location_count": 13,
      "location_summary": "Palo Alto, California • Sacramento, California • Darien, Connecticut + 10 more",
      "locations": [
        {
          "city": "Palo Alto",
          "state": "California"
        },
        {
          "city": "Sacramento",
          "state": "California"
        },
        {
          "city": "Darien",
          "state": "Connecticut"
        },
        {
          "city": "Aventura",
          "state": "Florida"
        },
        {
          "city": "Atlanta",
          "state": "Georgia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03257254"
    },
    {
      "nct_id": "NCT07089602",
      "title": "Trial Assessing the Efficacy of Human Placental Membrane Products and Standard of Care Versus Standard of Care Alone in the Management of Nonhealing Diabetic Foot Ulcers and Venous Leg Ulcers",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Diabetic Foot",
        "DFU",
        "Diabetic Foot Ulcer",
        "Foot Ulcer, Diabetic",
        "Ulcer Foot",
        "Venous Leg Ulcer",
        "Leg Ulcer",
        "Leg Ulcers Venous",
        "Ulcer"
      ],
      "interventions": [
        {
          "name": "Standard of Care DFU",
          "type": "OTHER"
        },
        {
          "name": "Tri-Membrane Wrap™ DFU",
          "type": "OTHER"
        },
        {
          "name": "Membrane Wrap™ DFU",
          "type": "OTHER"
        },
        {
          "name": "Membrane Wrap-Lite™ DFU",
          "type": "OTHER"
        },
        {
          "name": "Membrane Wrap-Hydro™ DFU",
          "type": "OTHER"
        },
        {
          "name": "Standard of Care VLU",
          "type": "OTHER"
        },
        {
          "name": "Tri-Membrane Wrap™ VLU",
          "type": "OTHER"
        },
        {
          "name": "Membrane Wrap™ VLU",
          "type": "OTHER"
        },
        {
          "name": "Membrane Wrap-Lite™ VLU",
          "type": "OTHER"
        },
        {
          "name": "Membrane Wrap-Hydro™ VLU",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "BioLab Holdings",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 650,
      "start_date": "2025-07-15",
      "completion_date": "2027-07",
      "has_results": false,
      "last_update_posted_date": "2025-07-28",
      "last_synced_at": "2026-09-14T10:04:49.404Z",
      "location_count": 1,
      "location_summary": "Philidelphia, Pennsylvania",
      "locations": [
        {
          "city": "Philidelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07089602"
    },
    {
      "nct_id": "NCT04927702",
      "title": "Assessment of Wound Closure Comparing Synthetic Hybrid-Scale Fiber Matrix With Standard of Care in Treating Diabetic Foot Ulcers (DFU) and With Living Cellular Skin Substitute in Treating Venous Leg Ulcers (VLU)",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Diabetic Foot Ulcer",
        "Venous Leg Ulcer"
      ],
      "interventions": [
        {
          "name": "Synthetic Hybrid-Scale Fiber Matrix",
          "type": "DEVICE"
        },
        {
          "name": "Standard of Care",
          "type": "DEVICE"
        },
        {
          "name": "Living Cellular Skin Substitute",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Acera Surgical, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 48,
      "start_date": "2021-07-19",
      "completion_date": "2024-08-01",
      "has_results": true,
      "last_update_posted_date": "2026-02-27",
      "last_synced_at": "2026-09-14T10:04:49.404Z",
      "location_count": 6,
      "location_summary": "Vista, California • Jacksonville, Florida • Miami Beach, Florida + 3 more",
      "locations": [
        {
          "city": "Vista",
          "state": "California"
        },
        {
          "city": "Jacksonville",
          "state": "Florida"
        },
        {
          "city": "Miami Beach",
          "state": "Florida"
        },
        {
          "city": "Chicago",
          "state": "Illinois"
        },
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04927702"
    },
    {
      "nct_id": "NCT07223281",
      "title": "Real-World Effectiveness of Amniotic Membrane Allografts Versus Standard Wound Care in DFU, VLU, and PU",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Diabetic Foot Ulcer (DFU)",
        "Venous Leg Ulcers (VLUs)",
        "Pressure Ulcers, Bedsores, Decubitus Ulcer"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Legacy Medical Consultants",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 2400,
      "start_date": "2025-09-25",
      "completion_date": "2025-12",
      "has_results": false,
      "last_update_posted_date": "2025-11-10",
      "last_synced_at": "2026-09-14T10:04:49.404Z",
      "location_count": 4,
      "location_summary": "Colorado Springs, Colorado • Clinton Township, Michigan • Tulsa, Oklahoma + 1 more",
      "locations": [
        {
          "city": "Colorado Springs",
          "state": "Colorado"
        },
        {
          "city": "Clinton Township",
          "state": "Michigan"
        },
        {
          "city": "Tulsa",
          "state": "Oklahoma"
        },
        {
          "city": "Nitro",
          "state": "West Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07223281"
    },
    {
      "nct_id": "NCT06328010",
      "title": "Clinical Registry Collecting Real World Evidence on Wound Care Treatments",
      "overall_status": "ENROLLING_BY_INVITATION",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Wounds and Injuries",
        "Burns",
        "Mohs Surgery",
        "Diabetic Foot Ulcer Mixed",
        "Venous Leg Ulcer",
        "Non-healing Wound",
        "Trauma Injury",
        "Injury and Wounds",
        "Degloving Injuries",
        "Pressure Ulcers, Bedsores, Decubitus Ulcer"
      ],
      "interventions": [
        {
          "name": "Various types of wound care treatments",
          "type": "COMBINATION_PRODUCT"
        }
      ],
      "intervention_types": [
        "COMBINATION_PRODUCT"
      ],
      "sponsor": "Siddhey LLC",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 5000,
      "start_date": "2024-04-01",
      "completion_date": "2030-06-30",
      "has_results": false,
      "last_update_posted_date": "2026-03-11",
      "last_synced_at": "2026-09-14T10:04:49.404Z",
      "location_count": 12,
      "location_summary": "Scottsdale, Arizona • Tempe, Arizona • Tucson, Arizona + 8 more",
      "locations": [
        {
          "city": "Scottsdale",
          "state": "Arizona"
        },
        {
          "city": "Tempe",
          "state": "Arizona"
        },
        {
          "city": "Tucson",
          "state": "Arizona"
        },
        {
          "city": "Riverside",
          "state": "California"
        },
        {
          "city": "Hallandale",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06328010"
    },
    {
      "nct_id": "NCT06400875",
      "title": "Observational Study to Investigate the Use of Sterilized Porcine Placental Tissue in the Treatment of Chronic VLU",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Ulcer Venous",
        "Wound Heal"
      ],
      "interventions": [
        {
          "name": "InnovaMatrix® AC Sterilized, Porcine Placental Extracellular Matrix (ECM)",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "ConvaTec Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 37,
      "start_date": "2023-07-10",
      "completion_date": "2025-12-31",
      "has_results": false,
      "last_update_posted_date": "2025-05-29",
      "last_synced_at": "2026-09-14T10:04:49.404Z",
      "location_count": 1,
      "location_summary": "Cambridge, Massachusetts",
      "locations": [
        {
          "city": "Cambridge",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06400875"
    },
    {
      "nct_id": "NCT03818828",
      "title": "Subjects With Non-Healing Venous Leg Ulcers Treated With Standard Care Plus Cryopreserved Human Umbilical Cord (TTAX01)",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Venous Leg Ulcer"
      ],
      "interventions": [
        {
          "name": "TTAX01",
          "type": "BIOLOGICAL"
        },
        {
          "name": "Profore Compression Therapy",
          "type": "OTHER"
        },
        {
          "name": "Cadexomer Iodine dressing",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL",
        "OTHER"
      ],
      "sponsor": "BioTissue Holdings, Inc",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 31,
      "start_date": "2019-02-14",
      "completion_date": "2020-01-28",
      "has_results": false,
      "last_update_posted_date": "2020-09-03",
      "last_synced_at": "2026-09-14T10:04:49.404Z",
      "location_count": 6,
      "location_summary": "Carlsbad, California • Sylmar, California • North Chicago, Illinois + 3 more",
      "locations": [
        {
          "city": "Carlsbad",
          "state": "California"
        },
        {
          "city": "Sylmar",
          "state": "California"
        },
        {
          "city": "North Chicago",
          "state": "Illinois"
        },
        {
          "city": "Las Vegas",
          "state": "Nevada"
        },
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03818828"
    },
    {
      "nct_id": "NCT06707090",
      "title": "Tissue Repair Gel in Venous Leg Ulcers (US)",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Venous Leg Ulcer",
        "Venous Ulcer",
        "Venous Stasis Ulcer",
        "Venous Stasis",
        "Wound Heal",
        "Wounds",
        "Venous Insufficiency of Leg",
        "Non-healing Wound"
      ],
      "interventions": [
        {
          "name": "TR987 0.1% gel + Standard of Care",
          "type": "DRUG"
        },
        {
          "name": "Standard of care",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER"
      ],
      "sponsor": "TR Therapeutics",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 312,
      "start_date": "2025-01-28",
      "completion_date": "2028-02",
      "has_results": false,
      "last_update_posted_date": "2026-02-12",
      "last_synced_at": "2026-09-14T10:04:49.404Z",
      "location_count": 33,
      "location_summary": "Tucson, Arizona • Castro Valley, California • Fresno, California + 27 more",
      "locations": [
        {
          "city": "Tucson",
          "state": "Arizona"
        },
        {
          "city": "Castro Valley",
          "state": "California"
        },
        {
          "city": "Fresno",
          "state": "California"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "San Francisco",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06707090"
    },
    {
      "nct_id": "NCT06562296",
      "title": "Study Evaluating Several CAMPs in Nonhealing Diabetic Foot and Venous Leg Ulcers",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Diabetic Foot Ulcer",
        "Venous Leg Ulcer"
      ],
      "interventions": [
        {
          "name": "Amnion-Intermediate-Chorion",
          "type": "OTHER"
        },
        {
          "name": "Amnion-Chorion-Amnion",
          "type": "OTHER"
        },
        {
          "name": "Standard of Care",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "OTHER",
        "PROCEDURE"
      ],
      "sponsor": "Cellution Biologics",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "98 Years",
        "sex": "ALL",
        "summary": "18 Years to 98 Years"
      },
      "enrollment_count": 292,
      "start_date": "2024-10-14",
      "completion_date": "2026-01-16",
      "has_results": false,
      "last_update_posted_date": "2026-04-13",
      "last_synced_at": "2026-09-14T10:04:49.404Z",
      "location_count": 4,
      "location_summary": "Jacksonville, Florida • Cincinnati, Ohio • Weslaco, Texas + 1 more",
      "locations": [
        {
          "city": "Jacksonville",
          "state": "Florida"
        },
        {
          "city": "Cincinnati",
          "state": "Ohio"
        },
        {
          "city": "Weslaco",
          "state": "Texas"
        },
        {
          "city": "Kenosha",
          "state": "Wisconsin"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06562296"
    },
    {
      "nct_id": "NCT07701590",
      "title": "CAMPR-II RWE TRIAL: A Saline-hydrated Allogeneic Dual-layer Amniotic Membrane Product or a Synthetic, Resorbable Polymeric Wound Matrix to a Coarsened Exact Matched Retrospective Control Cohort of Hard to Heal DFUs and VLUs",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Wound, Foot",
        "Diabetic Foot Ulcer (DFU)",
        "Venus Leg Ulcer"
      ],
      "interventions": [
        {
          "name": "Microlyte®",
          "type": "DEVICE"
        },
        {
          "name": "IP 1: Membrane Wrap - Hydro",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Capsicure, LLC",
      "sponsor_class": "NETWORK",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 147,
      "start_date": "2026-06-22",
      "completion_date": "2026-12-20",
      "has_results": false,
      "last_update_posted_date": "2026-07-14",
      "last_synced_at": "2026-09-14T10:04:49.404Z",
      "location_count": 7,
      "location_summary": "San Diego, California • Coral Gables, Florida • Miami, Florida + 3 more",
      "locations": [
        {
          "city": "San Diego",
          "state": "California"
        },
        {
          "city": "Coral Gables",
          "state": "Florida"
        },
        {
          "city": "Miami",
          "state": "Florida"
        },
        {
          "city": "Miami",
          "state": "Florida"
        },
        {
          "city": "Indianapolis",
          "state": "Indiana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07701590"
    }
  ]
}