{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Standard-Lung+Protective+Ventilation", "query": { "intervention": "Standard-Lung Protective Ventilation" }, "page_size": 10 }, "pagination": { "page": 1, "page_size": 10, "total_count": 16, "total_pages": 2, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Standard-Lung+Protective+Ventilation&page=2&page_size=10", "previous_page_url": null }, "source": "remote", "last_synced_at": "2026-09-15T20:44:46.193Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT04663802", "title": "Implementation of Nudges to Promote Utilization of Low Tidal Volume Ventilation (INPUT) Study", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "ARDS", "Critical Illness", "Acute Respiratory Distress Syndrome", "Acute Respiratory Failure" ], "interventions": [ { "name": "Default order set", "type": "BEHAVIORAL" }, { "name": "Physician-targeted accountable justification", "type": "BEHAVIORAL" }, { "name": "Respiratory therapist (RT)-targeted accountable justification", "type": "BEHAVIORAL" } ], "intervention_types": [ "BEHAVIORAL" ], "sponsor": "University of Pennsylvania", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "99 Years", "sex": "ALL", "summary": "18 Years to 99 Years" }, "enrollment_count": 7342, "start_date": "2021-02-22", "completion_date": "2023-12-15", "has_results": true, "last_update_posted_date": "2024-10-08", "last_synced_at": "2026-09-15T20:44:46.193Z", "location_count": 5, "location_summary": "Plainsboro, New Jersey • Philadelphia, Pennsylvania • West Chester, Pennsylvania", "locations": [ { "city": "Plainsboro", "state": "New Jersey" }, { "city": "Philadelphia", "state": "Pennsylvania" }, { "city": "Philadelphia", "state": "Pennsylvania" }, { "city": "Philadelphia", "state": "Pennsylvania" }, { "city": "West Chester", "state": "Pennsylvania" } ], "official_url": "https://clinicaltrials.gov/study/NCT04663802" }, { "nct_id": "NCT00747045", "title": "Lung Protective Ventilation in Pulmonary Thromboendarterectomy (PTE) Patients", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Chronic Thromboembolic Pulmonary Hypertension", "Acute Lung Injury" ], "interventions": [ { "name": "Ventilation Strategy", "type": "OTHER" } ], "intervention_types": [ "OTHER" ], "sponsor": "University of California, San Diego", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 128, "start_date": "2008-08", "completion_date": "2011-03", "has_results": false, "last_update_posted_date": "2014-12-03", "last_synced_at": "2026-09-15T20:44:46.193Z", "location_count": 1, "location_summary": "La Jolla, California", "locations": [ { "city": "La Jolla", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT00747045" }, { "nct_id": "NCT04488081", "title": "I-SPY COVID-19 TRIAL: An Adaptive Platform Trial for Critically Ill Patients", "overall_status": "ACTIVE_NOT_RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "COVID-19" ], "interventions": [ { "name": "Remdesivir", "type": "DRUG" }, { "name": "Imatinib Mesylate", "type": "DRUG" }, { "name": "Dexamethasone", "type": "DRUG" }, { "name": "Cenicriviroc", "type": "DRUG" }, { "name": "Icatibant", "type": "DRUG" }, { "name": "Apremilast", "type": "DRUG" }, { "name": "dornase alfa", "type": "BIOLOGICAL" }, { "name": "Celecoxib", "type": "DRUG" }, { "name": "Famotidine", "type": "DRUG" }, { "name": "IC14", "type": "BIOLOGICAL" }, { "name": "Aviptadil", "type": "DRUG" }, { "name": "narsoplimab", "type": "BIOLOGICAL" }, { "name": "Cyproheptadine", "type": "DRUG" }, { "name": "Cyclosporine", "type": "DRUG" } ], "intervention_types": [ "DRUG", "BIOLOGICAL" ], "sponsor": "QuantumLeap Healthcare Collaborative", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 1500, "start_date": "2020-07-31", "completion_date": "2030-07-31", "has_results": false, "last_update_posted_date": "2026-03-16", "last_synced_at": "2026-09-15T20:44:46.193Z", "location_count": 36, "location_summary": "Birmingham, Alabama • Davis, California • Irvine, California + 30 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "Davis", "state": "California" }, { "city": "Irvine", "state": "California" }, { "city": "Long Beach", "state": "California" }, { "city": "Los Angeles", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT04488081" }, { "nct_id": "NCT02158923", "title": "Individualized Perioperative Open Lung Ventilatory Strategy", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Moderated-high Risk of Postoperative Pulmonary Complication", "Abdominal Surgery Expected More Than Two Hours" ], "interventions": [ { "name": "Alveolar recruitment maneuver", "type": "PROCEDURE" }, { "name": "Calculation of optimal PEEP", "type": "PROCEDURE" }, { "name": "Postoperative CPAP", "type": "PROCEDURE" } ], "intervention_types": [ "PROCEDURE" ], "sponsor": "Fundación para la Investigación del Hospital Clínico de Valencia", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 920, "start_date": "2014-09", "completion_date": "2016-04", "has_results": false, "last_update_posted_date": "2016-05-17", "last_synced_at": "2026-09-15T20:44:46.193Z", "location_count": 1, "location_summary": "Boston, Massachusetts", "locations": [ { "city": "Boston", "state": "Massachusetts" } ], "official_url": "https://clinicaltrials.gov/study/NCT02158923" }, { "nct_id": "NCT01116921", "title": "Laryngeal Mask Airway (LMA) for Surfactant Administration in Neonates", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Respiratory Distress Syndrome" ], "interventions": [ { "name": "Nasal continuous positive airway pressure (nCPAP)", "type": "DEVICE" }, { "name": "Laryngeal Mask Airway (LMA) to deliver surfactant", "type": "DEVICE" }, { "name": "Surfactants, Pulmonary", "type": "DRUG" } ], "intervention_types": [ "DEVICE", "DRUG" ], "sponsor": "University of Minnesota", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": null, "maximum_age": "36 Hours", "sex": "ALL", "summary": "Up to 36 Hours" }, "enrollment_count": 103, "start_date": "2011-02", "completion_date": "2015-04", "has_results": true, "last_update_posted_date": "2017-02-27", "last_synced_at": "2026-09-15T20:44:46.193Z", "location_count": 7, "location_summary": "Loma Linda, California • San Diego, California • Maple Grove, Minnesota + 4 more", "locations": [ { "city": "Loma Linda", "state": "California" }, { "city": "San Diego", "state": "California" }, { "city": "Maple Grove", "state": "Minnesota" }, { "city": "Minneapolis", "state": "Minnesota" }, { "city": "Robbinsdale", "state": "Minnesota" } ], "official_url": "https://clinicaltrials.gov/study/NCT01116921" }, { "nct_id": "NCT03439995", "title": "Goal of Open Lung Ventilation in Donors", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Brain Death", "Organ Donation", "Organ Transplant Failure or Rejection" ], "interventions": [ { "name": "Open lung protective ventilation", "type": "OTHER" }, { "name": "Conventional ventilation", "type": "OTHER" } ], "intervention_types": [ "OTHER" ], "sponsor": "Vanderbilt University Medical Center", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "13 Years", "maximum_age": null, "sex": "ALL", "summary": "13 Years and older" }, "enrollment_count": 154, "start_date": "2018-07-09", "completion_date": "2021-01-01", "has_results": false, "last_update_posted_date": "2021-05-06", "last_synced_at": "2026-09-15T20:44:46.193Z", "location_count": 4, "location_summary": "Los Angeles, California • Palo Alto, California • San Francisco, California + 1 more", "locations": [ { "city": "Los Angeles", "state": "California" }, { "city": "Palo Alto", "state": "California" }, { "city": "San Francisco", "state": "California" }, { "city": "San Ramon", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT03439995" }, { "nct_id": "NCT05709041", "title": "Effect of Transpulmonary Pressure Guided Ventilation on Intraoperative Right Heart Function", "overall_status": "UNKNOWN", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Obesity", "Surgery", "Anesthesia", "Echocardiography, Transesophageal", "Mechanical Ventilation" ], "interventions": [ { "name": "Individualized lung-protective ventilation", "type": "OTHER" }, { "name": "Standard lung-protective ventilation", "type": "OTHER" } ], "intervention_types": [ "OTHER" ], "sponsor": "University of Vermont Medical Center", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 50, "start_date": "2023-01-30", "completion_date": "2026-03-15", "has_results": false, "last_update_posted_date": "2023-02-01", "last_synced_at": "2026-09-15T20:44:46.193Z", "location_count": 1, "location_summary": "Burlington, Vermont", "locations": [ { "city": "Burlington", "state": "Vermont" } ], "official_url": "https://clinicaltrials.gov/study/NCT05709041" }, { "nct_id": "NCT06832306", "title": "STimulation to Activate RespIration", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "ARDS (Moderate or Severe)", "AHRF", "Mechanically Ventilated ICU Patients" ], "interventions": [ { "name": "Phrenic Nerve Stimulation", "type": "DEVICE" } ], "intervention_types": [ "DEVICE" ], "sponsor": "Lungpacer Medical Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 30, "start_date": "2025-05-28", "completion_date": "2027-03-31", "has_results": false, "last_update_posted_date": "2026-08-06", "last_synced_at": "2026-09-15T20:44:46.193Z", "location_count": 6, "location_summary": "La Jolla, California • Shreveport, Louisiana • Winston-Salem, North Carolina + 3 more", "locations": [ { "city": "La Jolla", "state": "California" }, { "city": "Shreveport", "state": "Louisiana" }, { "city": "Winston-Salem", "state": "North Carolina" }, { "city": "Cleveland", "state": "Ohio" }, { "city": "Philadelphia", "state": "Pennsylvania" } ], "official_url": "https://clinicaltrials.gov/study/NCT06832306" }, { "nct_id": "NCT07277244", "title": "Low-Intensity Mechanical Ventilation in the Operating Room: a Pilot Study", "overall_status": "ENROLLING_BY_INVITATION", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Robotic Surgery", "Post Operative Pulmonary Complications" ], "interventions": [ { "name": "Low Intensity Mechanical Ventilation", "type": "DEVICE" } ], "intervention_types": [ "DEVICE" ], "sponsor": "Beth Israel Deaconess Medical Center", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 60, "start_date": "2026-04-02", "completion_date": "2027-03-31", "has_results": false, "last_update_posted_date": "2026-08-21", "last_synced_at": "2026-09-15T20:44:46.193Z", "location_count": 1, "location_summary": "Boston, Massachusetts", "locations": [ { "city": "Boston", "state": "Massachusetts" } ], "official_url": "https://clinicaltrials.gov/study/NCT07277244" }, { "nct_id": "NCT06895148", "title": "ADHERE-LPV Advancing Delivery of High-Quality Evidence-Based Respiratory Efforts in Lung-Protective Ventilation", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Ventilation" ], "interventions": [ { "name": "New ventilator", "type": "DEVICE" }, { "name": "control ventilator", "type": "DEVICE" } ], "intervention_types": [ "DEVICE" ], "sponsor": "University of Minnesota", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 1125, "start_date": "2025-07-01", "completion_date": "2026-12-31", "has_results": false, "last_update_posted_date": "2026-07-09", "last_synced_at": "2026-09-15T20:44:46.193Z", "location_count": 1, "location_summary": "Minneapolis, Minnesota", "locations": [ { "city": "Minneapolis", "state": "Minnesota" } ], "official_url": "https://clinicaltrials.gov/study/NCT06895148" } ] }