{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Stannous+fluoride+dentifrice&page=2",
    "query": {
      "intervention": "Stannous fluoride dentifrice",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 60,
    "total_pages": 6,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Stannous+fluoride+dentifrice&page=3&page_size=10",
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Stannous+fluoride+dentifrice&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-10-07T20:43:03.448Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT06659471",
      "title": "Brief Title: a Clinical Study to Assess Gingivitis",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Gingival Diseases"
      ],
      "interventions": [
        {
          "name": "0.76% Sodium Monofluorophosphate Dentifrice",
          "type": "DRUG"
        },
        {
          "name": "0.454% Stannous Fluoride Dentifrice",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Procter and Gamble",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 120,
      "start_date": "2022-03-07",
      "completion_date": "2022-06-06",
      "has_results": false,
      "last_update_posted_date": "2024-10-26",
      "last_synced_at": "2026-10-07T20:43:03.448Z",
      "location_count": 1,
      "location_summary": "Las Vegas, Nevada",
      "locations": [
        {
          "city": "Las Vegas",
          "state": "Nevada"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06659471"
    },
    {
      "nct_id": "NCT01128946",
      "title": "Enamel Remineralization Potential of Dentifrices in Situ",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Dental Caries"
      ],
      "interventions": [
        {
          "name": "NaF",
          "type": "DRUG"
        },
        {
          "name": "SnF",
          "type": "DRUG"
        },
        {
          "name": "NaMFP",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "GlaxoSmithKline",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 83,
      "start_date": "2009-11",
      "completion_date": "2010-03",
      "has_results": true,
      "last_update_posted_date": "2015-01-01",
      "last_synced_at": "2026-10-07T20:43:03.448Z",
      "location_count": 1,
      "location_summary": "Indianapolis, Indiana",
      "locations": [
        {
          "city": "Indianapolis",
          "state": "Indiana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01128946"
    },
    {
      "nct_id": "NCT07738198",
      "title": "Dentin Hypersensitivity Reduction Efficacy Clinical",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Dental Hypersensitivity"
      ],
      "interventions": [
        {
          "name": "0.454% stannous fluoride toothpaste",
          "type": "DRUG"
        },
        {
          "name": "5% potassium nitrate",
          "type": "DRUG"
        },
        {
          "name": "0.76% sodium monofluorophosphate",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Colgate Palmolive",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "18 Years to 70 Years"
      },
      "enrollment_count": 116,
      "start_date": "2018-11-26",
      "completion_date": "2018-12-08",
      "has_results": false,
      "last_update_posted_date": "2026-07-31",
      "last_synced_at": "2026-10-07T20:43:03.448Z",
      "location_count": 1,
      "location_summary": "Costa Mesa, California",
      "locations": [
        {
          "city": "Costa Mesa",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07738198"
    },
    {
      "nct_id": "NCT03970759",
      "title": "Meta-analysis of Stannous Fluoride and the Effects on Gingival Health",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Gingivitis"
      ],
      "interventions": [
        {
          "name": "Stannous Fluoride Dentifrice",
          "type": "DRUG"
        },
        {
          "name": "Positive control dentifrice",
          "type": "DRUG"
        },
        {
          "name": "Negative control dentifrice",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Procter and Gamble",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 2890,
      "start_date": "2018-01-08",
      "completion_date": "2018-11-30",
      "has_results": false,
      "last_update_posted_date": "2019-06-17",
      "last_synced_at": "2026-10-07T20:43:03.448Z",
      "location_count": 1,
      "location_summary": "Cincinnati, Ohio",
      "locations": [
        {
          "city": "Cincinnati",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03970759"
    },
    {
      "nct_id": "NCT07704905",
      "title": "A Study to Investigate the Efficacy of an Experimental Dentifrice Containing Stannous Fluoride in Improving Gingival Health",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Dental Plaque",
        "Gingivitis"
      ],
      "interventions": [
        {
          "name": "Test Dentifrice",
          "type": "DRUG"
        },
        {
          "name": "Reference Dentifrice (Colgate Cavity Protection Dentifrice)",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "HALEON",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 110,
      "start_date": "2026-07-13",
      "completion_date": "2026-09-30",
      "has_results": false,
      "last_update_posted_date": "2026-10-07",
      "last_synced_at": "2026-10-07T20:43:03.448Z",
      "location_count": 1,
      "location_summary": "Fort Wayne, Indiana",
      "locations": [
        {
          "city": "Fort Wayne",
          "state": "Indiana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07704905"
    },
    {
      "nct_id": "NCT00762177",
      "title": "Investigate Oral Bacteria in Adult Population",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Oral Bacteria"
      ],
      "interventions": [
        {
          "name": "Fluoride",
          "type": "DRUG"
        },
        {
          "name": "Fluoride, Triclosan",
          "type": "DRUG"
        },
        {
          "name": "Stannous Fluoride",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Colgate Palmolive",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "18 Years to 70 Years"
      },
      "enrollment_count": 24,
      "start_date": "2008-05",
      "completion_date": "2008-09",
      "has_results": true,
      "last_update_posted_date": "2011-03-23",
      "last_synced_at": "2026-10-07T20:43:03.448Z",
      "location_count": 1,
      "location_summary": "Newark, New York",
      "locations": [
        {
          "city": "Newark",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00762177"
    },
    {
      "nct_id": "NCT01494649",
      "title": "Pilot Study to Investigate the Efficacy of a Toothpaste in Providing Relief From Dentinal Hypersensitivity",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Dentinal Sensitivity",
        "Hypersensitivity"
      ],
      "interventions": [
        {
          "name": "Test Toothpaste",
          "type": "DRUG"
        },
        {
          "name": "Negative Control Toothpaste",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "GlaxoSmithKline",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 118,
      "start_date": "2011-09",
      "completion_date": "2011-09",
      "has_results": true,
      "last_update_posted_date": "2013-05-08",
      "last_synced_at": "2026-10-07T20:43:03.448Z",
      "location_count": 1,
      "location_summary": "Las Vegas, Nevada",
      "locations": [
        {
          "city": "Las Vegas",
          "state": "Nevada"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01494649"
    },
    {
      "nct_id": "NCT07419672",
      "title": "Intra Oral Application (IOA) Testing Study of a Stannous Toothpaste",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Dental Caries"
      ],
      "interventions": [
        {
          "name": "Negative Control Treatment Slurry (Fluoride-Free)",
          "type": "DRUG"
        },
        {
          "name": "Active Comparator Fluoride Treatment (0.454% SnF)",
          "type": "DRUG"
        },
        {
          "name": "Test Fluoride Treatment (0.454% SnF) (Investigational Toothpaste)",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Church & Dwight Company, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 31,
      "start_date": "2024-08-12",
      "completion_date": "2024-11-21",
      "has_results": false,
      "last_update_posted_date": "2026-02-19",
      "last_synced_at": "2026-10-07T20:43:03.448Z",
      "location_count": 1,
      "location_summary": "Noblesville, Indiana",
      "locations": [
        {
          "city": "Noblesville",
          "state": "Indiana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07419672"
    },
    {
      "nct_id": "NCT04005417",
      "title": "Meta-analysis of Stannous Fluoride Dentifrice and the Effects on Dentine Hypersensitivity",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Dentine Hypersensitivity"
      ],
      "interventions": [
        {
          "name": "Stannous fluoride dentifrice",
          "type": "DRUG"
        },
        {
          "name": "Positive control dentifrice",
          "type": "DRUG"
        },
        {
          "name": "Negative control dentifrice",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Procter and Gamble",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 1036,
      "start_date": "2018-01-08",
      "completion_date": "2018-11-30",
      "has_results": false,
      "last_update_posted_date": "2019-07-02",
      "last_synced_at": "2026-10-07T20:43:03.448Z",
      "location_count": 1,
      "location_summary": "Cincinnati, Ohio",
      "locations": [
        {
          "city": "Cincinnati",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04005417"
    },
    {
      "nct_id": "NCT07419737",
      "title": "Dental Plaque Prevention Efficacy of a Stannous Fluoride Toothpaste",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Dental Plaque"
      ],
      "interventions": [
        {
          "name": "Stannous Fluoride Toothpaste (SnF)",
          "type": "DRUG"
        },
        {
          "name": "Sodium Fluoride Dentifrice",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Church & Dwight Company, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "69 Years",
        "sex": "ALL",
        "summary": "18 Years to 69 Years"
      },
      "enrollment_count": 91,
      "start_date": "2024-10-16",
      "completion_date": "2024-12-04",
      "has_results": false,
      "last_update_posted_date": "2026-02-19",
      "last_synced_at": "2026-10-07T20:43:03.448Z",
      "location_count": 1,
      "location_summary": "Fort Wayne, Indiana",
      "locations": [
        {
          "city": "Fort Wayne",
          "state": "Indiana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07419737"
    }
  ]
}