{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Subconjunctival+Lidocaine",
    "query": {
      "intervention": "Subconjunctival Lidocaine"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 6,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-10-28T12:42:48.143Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT07895420",
      "title": "Comparing Intravitreal Injection Pain Scores Using Iheezo (Chloroprocaine Hcl Ophthalmic Gel 3%) Versus Subconjunctival Lidocaine (2%): A Randomized, Controlled Trial",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "No Condition"
      ],
      "interventions": [
        {
          "name": "chloroprocaine HCL 3%",
          "type": "DRUG"
        },
        {
          "name": "Subconjunctival Lidocaine",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Retina Research Institute, LLC",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 80,
      "start_date": "2025-10-30",
      "completion_date": "2026-12-30",
      "has_results": false,
      "last_update_posted_date": "2026-10-26",
      "last_synced_at": "2026-10-28T12:42:48.143Z",
      "location_count": 4,
      "location_summary": "Glen Carbon, Illinois • Chesterfield, Missouri • City of Saint Peters, Missouri + 1 more",
      "locations": [
        {
          "city": "Glen Carbon",
          "state": "Illinois"
        },
        {
          "city": "Chesterfield",
          "state": "Missouri"
        },
        {
          "city": "City of Saint Peters",
          "state": "Missouri"
        },
        {
          "city": "St Louis",
          "state": "Missouri"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07895420"
    },
    {
      "nct_id": "NCT07456826",
      "title": "Study Evaluating the Efficacy and Safety of Chloroprocaine HCl Ophthalmic Gel 3% vs Proparacaine Ophthalmic Solution 0.5% Plus Subconjunctival Lidocaine in Patients Undergoing Intravitreal Injections",
      "overall_status": "ENROLLING_BY_INVITATION",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Diabetic Macular Edema (DME)",
        "Age-Related Macular Degeneration (AMD)",
        "Retinal Vein Occlusion",
        "Diabetic Retinopathy (DR)"
      ],
      "interventions": [
        {
          "name": "Chloroprocaine Ophthalmic Gel 3% (IHEEZO)",
          "type": "DRUG"
        },
        {
          "name": "Sham Subconjunctival Injection",
          "type": "PROCEDURE"
        },
        {
          "name": "Proparacaine Hydrochloride Ophthalmic Solution 0.5%",
          "type": "DRUG"
        },
        {
          "name": "Lidocaine Hydrochloride Injection 2%",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG",
        "PROCEDURE"
      ],
      "sponsor": "Harrow Inc",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 236,
      "start_date": "2026-03-31",
      "completion_date": "2026-08",
      "has_results": false,
      "last_update_posted_date": "2026-04-07",
      "last_synced_at": "2026-10-28T12:42:48.143Z",
      "location_count": 1,
      "location_summary": "Tyler, Texas",
      "locations": [
        {
          "city": "Tyler",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07456826"
    },
    {
      "nct_id": "NCT01350024",
      "title": "Comparison of Postoperative Pain With Two Different Types of Local Anesthesia in Surgery for a Drooping Eyelid",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Blepharoptosis"
      ],
      "interventions": [
        {
          "name": "Frontal nerve block with 2% lidocaine with 1:100,000 dilution of epinephrine",
          "type": "PROCEDURE"
        },
        {
          "name": "Subconjunctival injection of 2% lidocaine with 1:100,000 dilution with epinephrine",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "University of Miami",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "100 Years",
        "sex": "ALL",
        "summary": "18 Years to 100 Years"
      },
      "enrollment_count": 34,
      "start_date": "2011-05-01",
      "completion_date": "2016-07-30",
      "has_results": false,
      "last_update_posted_date": "2017-05-30",
      "last_synced_at": "2026-10-28T12:42:48.143Z",
      "location_count": 1,
      "location_summary": "Miami, Florida",
      "locations": [
        {
          "city": "Miami",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01350024"
    },
    {
      "nct_id": "NCT01640171",
      "title": "Anesthesia Preference for Intravitreal Injection: Topical or Subconjunctival",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Age-related Macular Degeneration",
        "Central Retinal Vein Occlusion",
        "Diabetic Macular Edema"
      ],
      "interventions": [
        {
          "name": "Xylocaine 2% Injectable Anesthetic",
          "type": "PROCEDURE"
        },
        {
          "name": "Proparacaine Hydrochloride 0.5% Drop",
          "type": "DRUG"
        },
        {
          "name": "Tetravisc 0.5% Gel",
          "type": "DRUG"
        },
        {
          "name": "Acuvail",
          "type": "DRUG"
        },
        {
          "name": "Intra-vitreal Anti-VEGF Drug",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "PROCEDURE",
        "DRUG"
      ],
      "sponsor": "Retina Vitreous Associates of Florida",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 57,
      "start_date": "2012-07",
      "completion_date": "2013-10",
      "has_results": true,
      "last_update_posted_date": "2014-04-21",
      "last_synced_at": "2026-10-28T12:42:48.143Z",
      "location_count": 1,
      "location_summary": "Clearwater, Florida",
      "locations": [
        {
          "city": "Clearwater",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01640171"
    },
    {
      "nct_id": "NCT01675947",
      "title": "Intravitreal Injections of Sirolimus in the Treatment of Geographic Atrophy",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Geographic Atrophy"
      ],
      "interventions": [
        {
          "name": "Sirolimus",
          "type": "DRUG"
        },
        {
          "name": "Lidocaine",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "National Eye Institute (NEI)",
      "sponsor_class": "NIH",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "55 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "55 Years and older"
      },
      "enrollment_count": 52,
      "start_date": "2012-02",
      "completion_date": "2016-02",
      "has_results": false,
      "last_update_posted_date": "2015-12-10",
      "last_synced_at": "2026-10-28T12:42:48.143Z",
      "location_count": 13,
      "location_summary": "Loma Linda, California • Sacramento, California • Jacksonville, Florida + 10 more",
      "locations": [
        {
          "city": "Loma Linda",
          "state": "California"
        },
        {
          "city": "Sacramento",
          "state": "California"
        },
        {
          "city": "Jacksonville",
          "state": "Florida"
        },
        {
          "city": "Atlanta",
          "state": "Georgia"
        },
        {
          "city": "Chicago",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01675947"
    },
    {
      "nct_id": "NCT00769392",
      "title": "Pilot Study: A Randomized Trial Of Anesthetic Agents For Intravitreal Injection",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Macular Degeneration"
      ],
      "interventions": [
        {
          "name": "Proparacaine Ophthalmic",
          "type": "DRUG"
        },
        {
          "name": "Tetracaine Ophthalmic",
          "type": "DRUG"
        },
        {
          "name": "Lidocaine 4%",
          "type": "DRUG"
        },
        {
          "name": "Lidocaine 2% Injectable Solution",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Lahey Clinic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "40 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "40 Years and older"
      },
      "enrollment_count": 28,
      "start_date": "2008-09",
      "completion_date": "2009-08-12",
      "has_results": true,
      "last_update_posted_date": "2020-03-09",
      "last_synced_at": "2026-10-28T12:42:48.143Z",
      "location_count": 3,
      "location_summary": "Arlington, Massachusetts • Burlington, Massachusetts • Peabody, Massachusetts",
      "locations": [
        {
          "city": "Arlington",
          "state": "Massachusetts"
        },
        {
          "city": "Burlington",
          "state": "Massachusetts"
        },
        {
          "city": "Peabody",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00769392"
    }
  ]
}