{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Substance+P%2C&page=2", "query": { "intervention": "Substance P,", "page": 2 }, "page_size": 10 }, "pagination": { "page": 2, "page_size": 10, "total_count": 10, "total_pages": 1, "next_page_url": null, "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Substance+P%2C&page=1&page_size=10" }, "source": "remote", "last_synced_at": "2026-09-29T14:28:44.452Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT03738878", "title": "Mechanism(s) Underlying Hypotensive Response to ARB/NEP Inhibition - Aim 1", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Hypertension" ], "interventions": [ { "name": "Valsartan", "type": "DRUG" }, { "name": "LCZ696", "type": "DRUG" }, { "name": "Bradykinin", "type": "DRUG" }, { "name": "Substance P", "type": "DRUG" }, { "name": "BNP", "type": "DRUG" }, { "name": "Sitagliptin", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Vanderbilt University Medical Center", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "60 Years", "sex": "ALL", "summary": "18 Years to 60 Years" }, "enrollment_count": 4, "start_date": "2018-11-15", "completion_date": "2024-12-01", "has_results": true, "last_update_posted_date": "2025-08-03", "last_synced_at": "2026-09-29T14:28:44.452Z", "location_count": 1, "location_summary": "Nashville, Tennessee", "locations": [ { "city": "Nashville", "state": "Tennessee" } ], "official_url": "https://clinicaltrials.gov/study/NCT03738878" }, { "nct_id": "NCT00065936", "title": "Self-Injury: Diagnosis and Treatment", "overall_status": "UNKNOWN", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Self-Injurious Behavior", "Mental Retardation" ], "interventions": [ { "name": "Naltrexone hydrochloride", "type": "DRUG" }, { "name": "Transcutaneous sensory nerve stimulation", "type": "PROCEDURE" } ], "intervention_types": [ "DRUG", "PROCEDURE" ], "sponsor": "Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)", "sponsor_class": "NIH", "healthy_volunteers": false, "eligibility": { "minimum_age": "4 Years", "maximum_age": "25 Years", "sex": "ALL", "summary": "4 Years to 25 Years" }, "enrollment_count": 37, "start_date": "1997-07", "completion_date": "2002-06", "has_results": false, "last_update_posted_date": "2005-06-24", "last_synced_at": "2026-09-29T14:28:44.452Z", "location_count": 2, "location_summary": "Chapel Hill, North Carolina • Morganton, North Carolina", "locations": [ { "city": "Chapel Hill", "state": "North Carolina" }, { "city": "Morganton", "state": "North Carolina" } ], "official_url": "https://clinicaltrials.gov/study/NCT00065936" }, { "nct_id": "NCT06421935", "title": "M9466 Alone or in Combination in Advanced Solid Tumors (DDriver 501)", "overall_status": "ACTIVE_NOT_RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Advanced Solid Tumor" ], "interventions": [ { "name": "M9466", "type": "DRUG" }, { "name": "Tuvusertib", "type": "DRUG" }, { "name": "Abiraterone acetate", "type": "DRUG" }, { "name": "Prednisone/Prednisolone", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "EMD Serono Research & Development Institute, Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 60, "start_date": "2024-08-07", "completion_date": "2027-02-22", "has_results": false, "last_update_posted_date": "2026-09-09", "last_synced_at": "2026-09-29T14:28:44.452Z", "location_count": 2, "location_summary": "New York, New York • Houston, Texas", "locations": [ { "city": "New York", "state": "New York" }, { "city": "Houston", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT06421935" }, { "nct_id": "NCT02774525", "title": "Concurrent Treatment of Substance Abuse and Child Maltreatment", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Substance Use", "Child Maltreatment" ], "interventions": [ { "name": "Reinforcement for drug & alcohol abstinence", "type": "BEHAVIORAL" }, { "name": "Parenting intervention", "type": "BEHAVIORAL" }, { "name": "Treatment as usual (TAU)", "type": "BEHAVIORAL" } ], "intervention_types": [ "BEHAVIORAL" ], "sponsor": "University of South Carolina", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 200, "start_date": "2013-04", "completion_date": "2020-01-31", "has_results": false, "last_update_posted_date": "2021-05-12", "last_synced_at": "2026-09-29T14:28:44.452Z", "location_count": 1, "location_summary": "Columbia, South Carolina", "locations": [ { "city": "Columbia", "state": "South Carolina" } ], "official_url": "https://clinicaltrials.gov/study/NCT02774525" }, { "nct_id": "NCT00383786", "title": "Substance P Antagonist in the Treatment of Posttraumatic Stress Disorder", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "PTSD" ], "interventions": [ { "name": "NK1 Antagoist (GR205171)", "type": "DRUG" }, { "name": "Psychophysiology (Trauma Script)", "type": "PROCEDURE" }, { "name": "Psychophysiology (Verbal Threat)", "type": "PROCEDURE" }, { "name": "Psychophysiology (Fear Conditioning)", "type": "PROCEDURE" }, { "name": "Psychophysiology (Affective Modulation)", "type": "PROCEDURE" }, { "name": "Psychophysiology (Heart rate variability)", "type": "PROCEDURE" }, { "name": "Lumbar Puncture", "type": "PROCEDURE" }, { "name": "24-hour plasma sampling", "type": "PROCEDURE" }, { "name": "MRI", "type": "PROCEDURE" } ], "intervention_types": [ "DRUG", "PROCEDURE" ], "sponsor": "Baylor College of Medicine", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "18 Years to 65 Years" }, "enrollment_count": 47, "start_date": "2006-09", "completion_date": "2009-06", "has_results": true, "last_update_posted_date": "2019-07-31", "last_synced_at": "2026-09-29T14:28:44.452Z", "location_count": 2, "location_summary": "Bethesda, Maryland • New York, New York", "locations": [ { "city": "Bethesda", "state": "Maryland" }, { "city": "New York", "state": "New York" } ], "official_url": "https://clinicaltrials.gov/study/NCT00383786" }, { "nct_id": "NCT05422534", "title": "CoQ10 and Exercise for Mitochondrial Dysfunction in Advance Kidney Disease", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "End Stage Renal Disease" ], "interventions": [ { "name": "CoQ10", "type": "DIETARY_SUPPLEMENT" }, { "name": "Placebo", "type": "DRUG" }, { "name": "HB-HIIT", "type": "BEHAVIORAL" }, { "name": "Observational", "type": "BEHAVIORAL" } ], "intervention_types": [ "DIETARY_SUPPLEMENT", "DRUG", "BEHAVIORAL" ], "sponsor": "Vanderbilt University Medical Center", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "75 Years", "sex": "ALL", "summary": "18 Years to 75 Years" }, "enrollment_count": 156, "start_date": "2023-06-01", "completion_date": "2027-10-01", "has_results": false, "last_update_posted_date": "2026-01-02", "last_synced_at": "2026-09-29T14:28:44.452Z", "location_count": 2, "location_summary": "Sacramento, California • Nashville, Tennessee", "locations": [ { "city": "Sacramento", "state": "California" }, { "city": "Nashville", "state": "Tennessee" } ], "official_url": "https://clinicaltrials.gov/study/NCT05422534" }, { "nct_id": "NCT00513708", "title": "Facilitating Aftercare for Alcohol Detox Patients", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Alcohol Abuse", "Alcohol Dependence" ], "interventions": [ { "name": "Motivation Enhancement Therapy (MET)", "type": "BEHAVIORAL" }, { "name": "Peer-Twelve Step Facilitation (P-TSF)", "type": "BEHAVIORAL" } ], "intervention_types": [ "BEHAVIORAL" ], "sponsor": "State University of New York at Buffalo", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 150, "start_date": "2007-07", "completion_date": "2008-08", "has_results": true, "last_update_posted_date": "2020-10-14", "last_synced_at": "2026-09-29T14:28:44.452Z", "location_count": 1, "location_summary": "Buffalo, New York", "locations": [ { "city": "Buffalo", "state": "New York" } ], "official_url": "https://clinicaltrials.gov/study/NCT00513708" }, { "nct_id": "NCT02036281", "title": "A Phase 1 Study of Substance P-Saporin in Terminal Cancer Patients With Intractable Pain", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Terminally Ill", "Histologically-confirmed Advanced Cancer", "Pain, Intractable" ], "interventions": [ { "name": "Substance P-Saporin", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "University of Texas Southwestern Medical Center", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 23, "start_date": "2014-01", "completion_date": "2016-09-28", "has_results": false, "last_update_posted_date": "2018-05-15", "last_synced_at": "2026-09-29T14:28:44.452Z", "location_count": 2, "location_summary": "La Jolla, California • Dallas, Texas", "locations": [ { "city": "La Jolla", "state": "California" }, { "city": "Dallas", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT02036281" }, { "nct_id": "NCT00900068", "title": "Blood Samples From Patients on a Clinical Trial to CINV During HSCT", "overall_status": "TERMINATED", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Breast Cancer", "Chronic Myeloproliferative Disorders", "Gestational Trophoblastic Tumor", "Leukemia", "Lymphoma", "Multiple Myeloma and Plasma Cell Neoplasm", "Myelodysplastic Syndromes", "Myelodysplastic/Myeloproliferative Neoplasms", "Nausea and Vomiting", "Neuroblastoma", "Ovarian Cancer", "Testicular Germ Cell Tumor" ], "interventions": [ { "name": "immunoenzyme technique", "type": "OTHER" }, { "name": "laboratory biomarker analysis", "type": "OTHER" }, { "name": "medical chart review", "type": "OTHER" } ], "intervention_types": [ "OTHER" ], "sponsor": "OHSU Knight Cancer Institute", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "120 Years", "sex": "ALL", "summary": "18 Years to 120 Years" }, "enrollment_count": 9, "start_date": "2008-08", "completion_date": "2009-10", "has_results": false, "last_update_posted_date": "2017-05-09", "last_synced_at": "2026-09-29T14:28:44.452Z", "location_count": 1, "location_summary": "Portland, Oregon", "locations": [ { "city": "Portland", "state": "Oregon" } ], "official_url": "https://clinicaltrials.gov/study/NCT00900068" }, { "nct_id": "NCT01966718", "title": "Repository Corticotropin Injection To Treat Rheumatoid Arthritis Patients Who Have Failed Three Biologic Therapies.", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Rheumatoid Arthritis" ], "interventions": [ { "name": "Repository corticotropin injection", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Arthritis Treatment Center, Maryland", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "80 Years", "sex": "ALL", "summary": "18 Years to 80 Years" }, "enrollment_count": 8, "start_date": "2013-10", "completion_date": "2015-10", "has_results": true, "last_update_posted_date": "2016-08-18", "last_synced_at": "2026-09-29T14:28:44.452Z", "location_count": 1, "location_summary": "Frederick, Maryland", "locations": [ { "city": "Frederick", "state": "Maryland" } ], "official_url": "https://clinicaltrials.gov/study/NCT01966718" } ] }