{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Sulfur+hexafluoride+type-a+lipid+microspheres&page=2",
    "query": {
      "intervention": "Sulfur hexafluoride type-a lipid microspheres",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 26,
    "total_pages": 3,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Sulfur+hexafluoride+type-a+lipid+microspheres&page=3&page_size=10",
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Sulfur+hexafluoride+type-a+lipid+microspheres&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-10-09T06:39:17.550Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT03963999",
      "title": "Validating Ultrasound Biomarkers for Hepatic Sinusoidal Obstruction Syndrome in Pediatric Hematopoietic Cell Transplant Patients",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Sinusoidal Obstruction Syndrome",
        "Veno Occlusive Disease, Hepatic",
        "Bone Marrow Transplant Complications",
        "Stem Cell Transplant Complications"
      ],
      "interventions": [
        {
          "name": "Ultrasound Elastography",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Contrast Enhanced Ultrasound (CEUS)",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DIAGNOSTIC_TEST",
        "DRUG"
      ],
      "sponsor": "Children's Mercy Hospital Kansas City",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "1 Month",
        "maximum_age": "25 Years",
        "sex": "ALL",
        "summary": "1 Month to 25 Years"
      },
      "enrollment_count": 0,
      "start_date": "2020-04-01",
      "completion_date": "2025-04-01",
      "has_results": false,
      "last_update_posted_date": "2020-01-13",
      "last_synced_at": "2026-10-09T06:39:17.550Z",
      "location_count": 1,
      "location_summary": "Kansas City, Missouri",
      "locations": [
        {
          "city": "Kansas City",
          "state": "Missouri"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03963999"
    },
    {
      "nct_id": "NCT06171607",
      "title": "Contrast Enhanced Ultrasound Medical Imaging for Identifying Breast Masses",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Breast Carcinoma"
      ],
      "interventions": [
        {
          "name": "Contrast-Enhanced Ultrasound",
          "type": "PROCEDURE"
        },
        {
          "name": "Perflutren Lipid Microspheres",
          "type": "DRUG"
        },
        {
          "name": "Sulfur Hexafluoride Lipid Microspheres",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "PROCEDURE",
        "DRUG"
      ],
      "sponsor": "University of Southern California",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "18 Years and older · Female only"
      },
      "enrollment_count": 100,
      "start_date": "2020-11-05",
      "completion_date": "2027-11-05",
      "has_results": false,
      "last_update_posted_date": "2026-02-02",
      "last_synced_at": "2026-10-09T06:39:17.550Z",
      "location_count": 2,
      "location_summary": "Los Angeles, California",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        },
        {
          "city": "Los Angeles",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06171607"
    },
    {
      "nct_id": "NCT02522481",
      "title": "Evaluation of Safety and Efficacy of Lumason/SonoVue in Subjects Undergoing Pharmacologic Stress BR1-141",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Coronary Artery Disease"
      ],
      "interventions": [
        {
          "name": "Lumason",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Bracco Diagnostics, Inc",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 175,
      "start_date": "2015-09-24",
      "completion_date": "2018-02-25",
      "has_results": true,
      "last_update_posted_date": "2021-06-11",
      "last_synced_at": "2026-10-09T06:39:17.550Z",
      "location_count": 10,
      "location_summary": "Tucson, Arizona • La Jolla, California • West Hills, California + 7 more",
      "locations": [
        {
          "city": "Tucson",
          "state": "Arizona"
        },
        {
          "city": "La Jolla",
          "state": "California"
        },
        {
          "city": "West Hills",
          "state": "California"
        },
        {
          "city": "Newark",
          "state": "Delaware"
        },
        {
          "city": "Indianapolis",
          "state": "Indiana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02522481"
    },
    {
      "nct_id": "NCT07145801",
      "title": "Y-90 Treatment Response Using Transarterial Radioembolization",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "HCC",
        "Hepatocellular Carcinoma",
        "Liver Cancer",
        "Hepatic Neoplasm",
        "Primary Liver Cancer",
        "Liver Neoplasm"
      ],
      "interventions": [
        {
          "name": "Lumason",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Sonazoid",
          "type": "DIAGNOSTIC_TEST"
        }
      ],
      "intervention_types": [
        "DIAGNOSTIC_TEST"
      ],
      "sponsor": "Thomas Jefferson University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 30,
      "start_date": "2025-09-11",
      "completion_date": "2027-06-30",
      "has_results": false,
      "last_update_posted_date": "2026-06-10",
      "last_synced_at": "2026-10-09T06:39:17.550Z",
      "location_count": 1,
      "location_summary": "Philadelphia, Pennsylvania",
      "locations": [
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07145801"
    },
    {
      "nct_id": "NCT03490929",
      "title": "CEUS for Blunt Abdominal Trauma in Children",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Trauma Abdomen"
      ],
      "interventions": [
        {
          "name": "Sulfur Hexafluoride Lipid Type A Microspheres 25 MG Intravenous Powder for Suspension [LUMASON]",
          "type": "DRUG"
        },
        {
          "name": "contrast-enhanced ultrasound",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DRUG",
        "DEVICE"
      ],
      "sponsor": "Children's Hospital of Philadelphia",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "0 Years",
        "maximum_age": "17 Years",
        "sex": "ALL",
        "summary": "0 Years to 17 Years"
      },
      "enrollment_count": 146,
      "start_date": "2018-06-01",
      "completion_date": "2026-12-31",
      "has_results": false,
      "last_update_posted_date": "2025-12-17",
      "last_synced_at": "2026-10-09T06:39:17.550Z",
      "location_count": 2,
      "location_summary": "Rochester, Minnesota • Philadelphia, Pennsylvania",
      "locations": [
        {
          "city": "Rochester",
          "state": "Minnesota"
        },
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03490929"
    },
    {
      "nct_id": "NCT03407001",
      "title": "Contrast Enhanced Ultrasound With Lumason in Detecting Liver Cancer in Participants With Cirrhosis",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "EARLY_PHASE1"
      ],
      "conditions": [
        "Cirrhosis"
      ],
      "interventions": [
        {
          "name": "Contrast-Enhanced Ultrasound",
          "type": "PROCEDURE"
        },
        {
          "name": "Sulfur Hexafluoride Lipid Microspheres",
          "type": "DRUG"
        },
        {
          "name": "Ultrasound",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE",
        "DRUG"
      ],
      "sponsor": "M.D. Anderson Cancer Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 9,
      "start_date": "2018-01-12",
      "completion_date": "2020-09-15",
      "has_results": false,
      "last_update_posted_date": "2020-10-14",
      "last_synced_at": "2026-10-09T06:39:17.550Z",
      "location_count": 1,
      "location_summary": "Houston, Texas",
      "locations": [
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03407001"
    },
    {
      "nct_id": "NCT06261814",
      "title": "Contrast Enhanced Ultrasound to Evaluate Response to Chemoembolization in Patients With Liver Tumors",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Liver Neoplasms"
      ],
      "interventions": [
        {
          "name": "Sulfur Hexafluoride Lipid Microspheres",
          "type": "DRUG"
        },
        {
          "name": "Contrast-Enhanced Ultrasound",
          "type": "PROCEDURE"
        },
        {
          "name": "Transarterial Chemoembolization",
          "type": "PROCEDURE"
        },
        {
          "name": "Medical Chart Review",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "PROCEDURE",
        "OTHER"
      ],
      "sponsor": "john eisenbrey",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 266,
      "start_date": "2024-08-07",
      "completion_date": "2028-01-01",
      "has_results": false,
      "last_update_posted_date": "2026-02-17",
      "last_synced_at": "2026-10-09T06:39:17.550Z",
      "location_count": 1,
      "location_summary": "Philadelphia, Pennsylvania",
      "locations": [
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06261814"
    },
    {
      "nct_id": "NCT04720456",
      "title": "SHAPE of Portal Hypertension in Children",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Hypertension, Portal"
      ],
      "interventions": [
        {
          "name": "SHAPE measurement using the ultrasound contrast agent Sonazoid (perfluorobutane microbubbles)",
          "type": "DRUG"
        },
        {
          "name": "SHAPE measurement using the ultrasound contrast agent Lumason (sulfur hexafluoride lipid-type A microspheres)",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Thomas Jefferson University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "6 Years",
        "maximum_age": "21 Years",
        "sex": "ALL",
        "summary": "6 Years to 21 Years"
      },
      "enrollment_count": 12,
      "start_date": "2021-11-03",
      "completion_date": "2026-09-08",
      "has_results": false,
      "last_update_posted_date": "2026-10-02",
      "last_synced_at": "2026-10-09T06:39:17.550Z",
      "location_count": 1,
      "location_summary": "Philadelphia, Pennsylvania",
      "locations": [
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04720456"
    },
    {
      "nct_id": "NCT03295656",
      "title": "Contrast-Enhanced Ultrasound Diagnosis of Acute Appendicitis",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Appendicitis Acute"
      ],
      "interventions": [
        {
          "name": "Sulfur hexafluoride lipid-type A microspheres",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Boston Children's Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "8 Years",
        "maximum_age": "17 Years",
        "sex": "ALL",
        "summary": "8 Years to 17 Years"
      },
      "enrollment_count": 0,
      "start_date": "2020-07-15",
      "completion_date": "2020-07-15",
      "has_results": false,
      "last_update_posted_date": "2020-07-17",
      "last_synced_at": "2026-10-09T06:39:17.550Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03295656"
    },
    {
      "nct_id": "NCT02786810",
      "title": "Contrast Enhanced Ultrasound for Evaluation of Reflux Nephropathy",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Urinary Tract Infection",
        "Vesicoureteral Reflux"
      ],
      "interventions": [
        {
          "name": "Sulfur hexafluoride type-a lipid microspheres",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Tennessee",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "8 Years",
        "maximum_age": "50 Years",
        "sex": "ALL",
        "summary": "8 Years to 50 Years"
      },
      "enrollment_count": 10,
      "start_date": "2016-03",
      "completion_date": "2016-11",
      "has_results": true,
      "last_update_posted_date": "2018-05-11",
      "last_synced_at": "2026-10-09T06:39:17.550Z",
      "location_count": 1,
      "location_summary": "Memphis, Tennessee",
      "locations": [
        {
          "city": "Memphis",
          "state": "Tennessee"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02786810"
    }
  ]
}