{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Surgical+Management&page=25", "query": { "intervention": "Surgical Management", "page": 25 }, "page_size": 10 }, "pagination": { "page": 25, "page_size": 10, "total_count": 3083, "total_pages": 309, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Surgical+Management&page=26&page_size=10", "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Surgical+Management&page=24&page_size=10" }, "source": "remote", "last_synced_at": "2026-11-15T13:23:42.809Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT04536077", "title": "Immunologic Effects of CDX-301 and CDX-1140 in Resectable Pancreatic Cancer Patients", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Pancreatic Cancer", "Cancer of the Pancreas", "Pancreas Cancer" ], "interventions": [ { "name": "CDX-301", "type": "DRUG" }, { "name": "CDX-1140", "type": "DRUG" }, { "name": "Research blood draw", "type": "PROCEDURE" } ], "intervention_types": [ "DRUG", "PROCEDURE" ], "sponsor": "Washington University School of Medicine", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 16, "start_date": "2021-08-13", "completion_date": "2023-11-21", "has_results": true, "last_update_posted_date": "2024-10-08", "last_synced_at": "2026-11-15T13:23:42.809Z", "location_count": 1, "location_summary": "St Louis, Missouri", "locations": [ { "city": "St Louis", "state": "Missouri" } ], "official_url": "https://clinicaltrials.gov/study/NCT04536077" }, { "nct_id": "NCT06059651", "title": "The Effects of Metabolic & Bariatric Surgery on Lipid Metabolism, Myeloid-Derived Suppressor Cells, and Cancer Cell Biology", "overall_status": "COMPLETED", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Obesity" ], "interventions": [ { "name": "Metabolic & Bariatric Surgery", "type": "PROCEDURE" } ], "intervention_types": [ "PROCEDURE" ], "sponsor": "Pennington Biomedical Research Center", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "35 Years", "maximum_age": "60 Years", "sex": "FEMALE", "summary": "35 Years to 60 Years · Female only" }, "enrollment_count": 11, "start_date": "2024-01-01", "completion_date": "2026-04-01", "has_results": true, "last_update_posted_date": "2026-09-15", "last_synced_at": "2026-11-15T13:23:42.809Z", "location_count": 1, "location_summary": "Baton Rouge, Louisiana", "locations": [ { "city": "Baton Rouge", "state": "Louisiana" } ], "official_url": "https://clinicaltrials.gov/study/NCT06059651" }, { "nct_id": "NCT04930783", "title": "NeoVax + CDX-301 and Nivolumab or Pembrolizumab in Melanoma", "overall_status": "ACTIVE_NOT_RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Melanoma", "Metastatic Melanoma" ], "interventions": [ { "name": "CDX-301", "type": "DRUG" }, { "name": "NEOVAX", "type": "BIOLOGICAL" }, { "name": "Nivolumab", "type": "DRUG" }, { "name": "Pembrolizumab", "type": "DRUG" } ], "intervention_types": [ "DRUG", "BIOLOGICAL" ], "sponsor": "Dana-Farber Cancer Institute", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 10, "start_date": "2022-01-03", "completion_date": "2030-09-30", "has_results": false, "last_update_posted_date": "2026-03-25", "last_synced_at": "2026-11-15T13:23:42.809Z", "location_count": 1, "location_summary": "Boston, Massachusetts", "locations": [ { "city": "Boston", "state": "Massachusetts" } ], "official_url": "https://clinicaltrials.gov/study/NCT04930783" }, { "nct_id": "NCT05420753", "title": "Body Composition Changes After TIPS and Associated Clinical Outcomes", "overall_status": "UNKNOWN", "study_type": "INTERVENTIONAL", "phases": [ "EARLY_PHASE1" ], "conditions": [ "Cirrhosis, Liver", "Sarcopenia" ], "interventions": [ { "name": "Transjugular Intrahepatic Portosystemic Shunt (TIPS) creation", "type": "PROCEDURE" } ], "intervention_types": [ "PROCEDURE" ], "sponsor": "Oregon Health and Science University", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "99 Years", "sex": "ALL", "summary": "18 Years to 99 Years" }, "enrollment_count": 22, "start_date": "2022-05-01", "completion_date": "2025-12-31", "has_results": false, "last_update_posted_date": "2023-11-07", "last_synced_at": "2026-11-15T13:23:42.809Z", "location_count": 1, "location_summary": "Portland, Oregon", "locations": [ { "city": "Portland", "state": "Oregon" } ], "official_url": "https://clinicaltrials.gov/study/NCT05420753" }, { "nct_id": "NCT04668872", "title": "Biopsy After Radioembolization to Identify Changes in Tumor Cells From the Radiation", "overall_status": "RECRUITING", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Colon Cancer Liver Metastasis", "Colon Cancer", "Adenocarcinoma of the Colon", "Adenocarcinoma of the Rectum", "Liver Metastasis Colon Cancer", "Colorectal Cancer" ], "interventions": [ { "name": "Y90 TARE", "type": "RADIATION" }, { "name": "PET/CT", "type": "DIAGNOSTIC_TEST" }, { "name": "PET/MRI", "type": "DIAGNOSTIC_TEST" } ], "intervention_types": [ "RADIATION", "DIAGNOSTIC_TEST" ], "sponsor": "Memorial Sloan Kettering Cancer Center", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 80, "start_date": "2020-12-07", "completion_date": "2026-12-07", "has_results": false, "last_update_posted_date": "2026-03-12", "last_synced_at": "2026-11-15T13:23:42.809Z", "location_count": 1, "location_summary": "New York, New York", "locations": [ { "city": "New York", "state": "New York" } ], "official_url": "https://clinicaltrials.gov/study/NCT04668872" }, { "nct_id": "NCT07582172", "title": "Total Marrow and Lymphoid Irradiation in Combination With Fludarabine and Melphalan as Conditioning for Allogeneic Peripheral Blood Stem Cell Hematopoietic Cell Transplant in Older Patients With Refractory and Relapsed Acute Myeloid Leukemia and High-risk Myelodysplastic Syndrome", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Acute Myeloid Leukemia With Complex Karyotype", "Myelodysplastic Chronic Myelomonocytic Leukemia", "Myelodysplastic Syndrome", "Recurrent Acute Myeloid Leukemia", "Recurrent Myelodysplastic Chronic Myelomonocytic Leukemia", "Recurrent Myelodysplastic Syndrome", "Recurrent Secondary Acute Myeloid Leukemia", "Refractory Acute Myeloid Leukemia", "Refractory Myelodysplastic Chronic Myelomonocytic Leukemia", "Refractory Myelodysplastic Syndrome", "Refractory Secondary Acute Myeloid Leukemia" ], "interventions": [ { "name": "Biospecimen Collection", "type": "PROCEDURE" }, { "name": "Bone Marrow Biopsy", "type": "PROCEDURE" }, { "name": "Computed Tomography", "type": "PROCEDURE" }, { "name": "Echocardiography Test", "type": "PROCEDURE" }, { "name": "Fludarabine Phosphate", "type": "DRUG" }, { "name": "Melphalan", "type": "DRUG" }, { "name": "Multigated Acquisition Scan", "type": "PROCEDURE" }, { "name": "Palifermin", "type": "BIOLOGICAL" }, { "name": "Peripheral Blood Stem Cell Transplantation", "type": "PROCEDURE" }, { "name": "Questionnaire Administration", "type": "OTHER" }, { "name": "Sirolimus", "type": "DRUG" }, { "name": "Tacrolimus", "type": "DRUG" }, { "name": "Total Marrow and Lymphoid Irradiation", "type": "RADIATION" } ], "intervention_types": [ "PROCEDURE", "DRUG", "BIOLOGICAL", "OTHER", "RADIATION" ], "sponsor": "City of Hope Medical Center", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 35, "start_date": "2026-11-05", "completion_date": "2031-11-05", "has_results": false, "last_update_posted_date": "2026-10-08", "last_synced_at": "2026-11-15T13:23:42.809Z", "location_count": 1, "location_summary": "Duarte, California", "locations": [ { "city": "Duarte", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT07582172" }, { "nct_id": "NCT01813695", "title": "Preemptive Genotyping and Pain Management", "overall_status": "COMPLETED", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Pain" ], "interventions": [ { "name": "Preemptive genotyping in medical record", "type": "PROCEDURE" }, { "name": "Genotyping not included in electronic medical record", "type": "PROCEDURE" } ], "intervention_types": [ "PROCEDURE" ], "sponsor": "Children's Hospital Medical Center, Cincinnati", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "6 Years", "maximum_age": "21 Years", "sex": "ALL", "summary": "6 Years to 21 Years" }, "enrollment_count": 576, "start_date": "2013-03", "completion_date": "2022-12-30", "has_results": false, "last_update_posted_date": "2024-02-22", "last_synced_at": "2026-11-15T13:23:42.809Z", "location_count": 1, "location_summary": "Cincinnati, Ohio", "locations": [ { "city": "Cincinnati", "state": "Ohio" } ], "official_url": "https://clinicaltrials.gov/study/NCT01813695" }, { "nct_id": "NCT06600880", "title": "Neuronavigation-guided FUS-induced BBB Opening in Alzheimer's Disease Patients and Its Effects on Brain Amyloid and Tau", "overall_status": "NOT_YET_RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Alzheimer Disease, Early Onset" ], "interventions": [ { "name": "Neuronavigation-guided single-element focused ultrasound transducer", "type": "DEVICE" }, { "name": "Lumason", "type": "DRUG" }, { "name": "Magnetic Resonance Imaging (MRI) with or without gadolinium contrast agents", "type": "OTHER" }, { "name": "Positron Emission Tomography (PET)", "type": "RADIATION" }, { "name": "Amyvid", "type": "DRUG" }, { "name": "MK-6240", "type": "DRUG" }, { "name": "Dotarem", "type": "DRUG" }, { "name": "Blood draw", "type": "DIAGNOSTIC_TEST" }, { "name": "UR5e", "type": "DEVICE" }, { "name": "Urine test", "type": "DIAGNOSTIC_TEST" } ], "intervention_types": [ "DEVICE", "DRUG", "OTHER", "RADIATION", "DIAGNOSTIC_TEST" ], "sponsor": "Columbia University", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "50 Years", "maximum_age": null, "sex": "ALL", "summary": "50 Years and older" }, "enrollment_count": 6, "start_date": "2027-08", "completion_date": "2028-12", "has_results": false, "last_update_posted_date": "2026-05-13", "last_synced_at": "2026-11-15T13:23:42.809Z", "location_count": 1, "location_summary": "New York, New York", "locations": [ { "city": "New York", "state": "New York" } ], "official_url": "https://clinicaltrials.gov/study/NCT06600880" }, { "nct_id": "NCT06568003", "title": "TraNsvenous TrIcuspid Valve ReplacemenT With LuX-Valve Plus System (TRINITY-US)", "overall_status": "ACTIVE_NOT_RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Tricuspid Regurgitation (TR)" ], "interventions": [ { "name": "Transcatheter Tricuspid Valve Intervention", "type": "DEVICE" } ], "intervention_types": [ "DEVICE" ], "sponsor": "Jenscare Innovation Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 15, "start_date": "2024-09-26", "completion_date": "2030-10", "has_results": false, "last_update_posted_date": "2026-03-02", "last_synced_at": "2026-11-15T13:23:42.809Z", "location_count": 3, "location_summary": "Los Angeles, California • Detroit, Michigan • New York, New York", "locations": [ { "city": "Los Angeles", "state": "California" }, { "city": "Detroit", "state": "Michigan" }, { "city": "New York", "state": "New York" } ], "official_url": "https://clinicaltrials.gov/study/NCT06568003" }, { "nct_id": "NCT06948786", "title": "Pirtobrutinib and Mosunetuzumab for the Treatment of Relapsed/Refractory Grades 1-3A Follicular Lymphoma, PROMOTE-FL Trial", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Grade 1 Follicular Lymphoma", "Grade 2 Follicular Lymphoma", "Grade 3a Follicular Lymphoma", "Recurrent Follicular Lymphoma", "Refractory Follicular Lymphoma" ], "interventions": [ { "name": "Pirtobrutinib", "type": "DRUG" }, { "name": "Mosunetuzumab", "type": "BIOLOGICAL" }, { "name": "Biospecimen Collection", "type": "PROCEDURE" }, { "name": "Biopsy Procedure", "type": "PROCEDURE" }, { "name": "Computed Tomography", "type": "PROCEDURE" }, { "name": "Positron Emission Tomography", "type": "PROCEDURE" }, { "name": "Bone Marrow Aspiration", "type": "PROCEDURE" }, { "name": "Bone Marrow Biopsy", "type": "PROCEDURE" }, { "name": "Questionnaire Administration", "type": "OTHER" } ], "intervention_types": [ "DRUG", "BIOLOGICAL", "PROCEDURE", "OTHER" ], "sponsor": "University of Washington", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 22, "start_date": "2025-11-17", "completion_date": "2031-07-31", "has_results": false, "last_update_posted_date": "2026-06-04", "last_synced_at": "2026-11-15T13:23:42.809Z", "location_count": 1, "location_summary": "Seattle, Washington", "locations": [ { "city": "Seattle", "state": "Washington" } ], "official_url": "https://clinicaltrials.gov/study/NCT06948786" } ] }