{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Surgical+Site+Infection",
    "query": {
      "intervention": "Surgical Site Infection"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 195,
    "total_pages": 20,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Surgical+Site+Infection&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-22T02:18:14.790Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT01798810",
      "title": "Supplemental Perioperative Oxygen to Reduce Surgical Site Infection After High Energy Fracture Surgery",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Post Operative Surgical Site Infection"
      ],
      "interventions": [
        {
          "name": "Supplemental Perioperative Oxygen",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Major Extremity Trauma Research Consortium",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 1171,
      "start_date": "2013-06",
      "completion_date": "2022-06-30",
      "has_results": false,
      "last_update_posted_date": "2026-05-05",
      "last_synced_at": "2026-09-22T02:18:14.790Z",
      "location_count": 2,
      "location_summary": "Phoenix, Arizona • Baltimore, Maryland",
      "locations": [
        {
          "city": "Phoenix",
          "state": "Arizona"
        },
        {
          "city": "Baltimore",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01798810"
    },
    {
      "nct_id": "NCT06860802",
      "title": "Precision Antibiotic Dosing for Appendectomy",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Appendicitis (Diagnosis)"
      ],
      "interventions": [
        {
          "name": "Cefoxitin",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Michigan",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 46,
      "start_date": "2025-02-28",
      "completion_date": "2026-09-30",
      "has_results": false,
      "last_update_posted_date": "2026-08-14",
      "last_synced_at": "2026-09-22T02:18:14.790Z",
      "location_count": 1,
      "location_summary": "Ann Arbor, Michigan",
      "locations": [
        {
          "city": "Ann Arbor",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06860802"
    },
    {
      "nct_id": "NCT03466489",
      "title": "Floraseal Versus Iodine Impregnated Adhesive Drapes",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Surgical Site Infection",
        "Surgical Wound Infection"
      ],
      "interventions": [
        {
          "name": "Floraseal",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of Miami",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 0,
      "start_date": "2018-01-01",
      "completion_date": "2020-02-01",
      "has_results": false,
      "last_update_posted_date": "2019-07-22",
      "last_synced_at": "2026-09-22T02:18:14.790Z",
      "location_count": 1,
      "location_summary": "Miami, Florida",
      "locations": [
        {
          "city": "Miami",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03466489"
    },
    {
      "nct_id": "NCT01905397",
      "title": "Negative Pressure Wound Therapy to Reduce Surgical Site Infection",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Patients Undergoing Hepatopancreatobiliary Surgery"
      ],
      "interventions": [
        {
          "name": "Conventional wound therapy",
          "type": "DEVICE"
        },
        {
          "name": "Negative pressure wound therapy",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Duke University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 164,
      "start_date": "2013-12-18",
      "completion_date": "2021-05-26",
      "has_results": true,
      "last_update_posted_date": "2022-12-02",
      "last_synced_at": "2026-09-22T02:18:14.790Z",
      "location_count": 2,
      "location_summary": "Indianapolis, Indiana • Durham, North Carolina",
      "locations": [
        {
          "city": "Indianapolis",
          "state": "Indiana"
        },
        {
          "city": "Durham",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01905397"
    },
    {
      "nct_id": "NCT03190668",
      "title": "Skeletal Muscle and Adipose Tissue Study",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Idiopathic Scoliosis"
      ],
      "interventions": [
        {
          "name": "Bolus dose of Cefazolin",
          "type": "DRUG"
        },
        {
          "name": "Continuous Cefazolin drip",
          "type": "DRUG"
        },
        {
          "name": "Paraspinal muscle microdialysis catheters",
          "type": "DEVICE"
        },
        {
          "name": "Subcutaneous microdialysis catheters",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DRUG",
        "DEVICE"
      ],
      "sponsor": "University of Florida",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "12 Years",
        "maximum_age": "20 Years",
        "sex": "ALL",
        "summary": "12 Years to 20 Years"
      },
      "enrollment_count": 12,
      "start_date": "2018-05-29",
      "completion_date": "2022-06-23",
      "has_results": true,
      "last_update_posted_date": "2023-07-11",
      "last_synced_at": "2026-09-22T02:18:14.790Z",
      "location_count": 1,
      "location_summary": "Gainesville, Florida",
      "locations": [
        {
          "city": "Gainesville",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03190668"
    },
    {
      "nct_id": "NCT01831154",
      "title": "The Effect of Tight Glycemic Control on Surgical Site Infection Rates in Patients Undergoing Open Heart Surgery",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Diabetes",
        "Hyperglycemia",
        "Surgical Site Infection"
      ],
      "interventions": [
        {
          "name": "Tight Glycemic",
          "type": "DRUG"
        },
        {
          "name": "Conventional Glycemic",
          "type": "DRUG"
        },
        {
          "name": "Standard Glycemic",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "James A. Haley Veterans Administration Hospital",
      "sponsor_class": "FED",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "21 Years and older"
      },
      "enrollment_count": 37,
      "start_date": "2010-05",
      "completion_date": "2011-10",
      "has_results": true,
      "last_update_posted_date": "2017-04-24",
      "last_synced_at": "2026-09-22T02:18:14.790Z",
      "location_count": 1,
      "location_summary": "Tampa, Florida",
      "locations": [
        {
          "city": "Tampa",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01831154"
    },
    {
      "nct_id": "NCT05523154",
      "title": "\"Answers in Hours\" A Randomized Controlled Trial Using Microbiome Metagenomics for Bile Duct Cultures",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Benign Pancreatic Neoplasm",
        "Malignant Pancreatic Neoplasm"
      ],
      "interventions": [
        {
          "name": "Biospecimen Collection",
          "type": "PROCEDURE"
        },
        {
          "name": "Laboratory Procedure",
          "type": "OTHER"
        },
        {
          "name": "Nanopore Sequencing",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "PROCEDURE",
        "OTHER",
        "DEVICE"
      ],
      "sponsor": "Mayo Clinic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 8,
      "start_date": "2023-01-19",
      "completion_date": "2023-11-27",
      "has_results": true,
      "last_update_posted_date": "2025-02-18",
      "last_synced_at": "2026-09-22T02:18:14.790Z",
      "location_count": 1,
      "location_summary": "Rochester, Minnesota",
      "locations": [
        {
          "city": "Rochester",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05523154"
    },
    {
      "nct_id": "NCT02385708",
      "title": "Use of 2% Chlorhexidine Cloths Reduce Surgical Site Infections",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Surgical Site Infection"
      ],
      "interventions": [
        {
          "name": "2% Chlorohexidine Gluconate Standard of Care",
          "type": "DRUG"
        },
        {
          "name": "2% Chlorohexidine Gluconate Chin to Toe",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Vanderbilt University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 163,
      "start_date": "2015-08",
      "completion_date": "2018-06-21",
      "has_results": true,
      "last_update_posted_date": "2019-04-30",
      "last_synced_at": "2026-09-22T02:18:14.790Z",
      "location_count": 1,
      "location_summary": "Nashville, Tennessee",
      "locations": [
        {
          "city": "Nashville",
          "state": "Tennessee"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02385708"
    },
    {
      "nct_id": "NCT01640925",
      "title": "Trial of 2% Chlorhexidine Bathing on Nosocomial Infections in the Surgical Intensive Care Unit",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Cross Infection",
        "Pneumonia, Ventilator-associated",
        "Catheter-related Infections",
        "Infection Due to Indwelling Urinary Catheter",
        "Surgical Wound Infection"
      ],
      "interventions": [
        {
          "name": "Chlorhexidine gluconate",
          "type": "DRUG"
        },
        {
          "name": "Standard bathing",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER"
      ],
      "sponsor": "Joshua Swan",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 350,
      "start_date": "2012-07",
      "completion_date": "2014-09",
      "has_results": true,
      "last_update_posted_date": "2018-04-27",
      "last_synced_at": "2026-09-22T02:18:14.790Z",
      "location_count": 1,
      "location_summary": "Houston, Texas",
      "locations": [
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01640925"
    },
    {
      "nct_id": "NCT03558984",
      "title": "D-PLEX 302: Efficacy and Safety of D-PLEX in the Prevention of Sternal Infection Post Cardiac Surgery",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Surgical Site Infection",
        "Sternal Infection",
        "Cardiac Surgery"
      ],
      "interventions": [
        {
          "name": "D-PLEX",
          "type": "DRUG"
        },
        {
          "name": "Standard of Care",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER"
      ],
      "sponsor": "PolyPid Ltd.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 2,
      "start_date": "2019-12-17",
      "completion_date": "2022-10-24",
      "has_results": true,
      "last_update_posted_date": "2026-06-30",
      "last_synced_at": "2026-09-22T02:18:14.790Z",
      "location_count": 2,
      "location_summary": "Rochester, Minnesota • Huston, Texas",
      "locations": [
        {
          "city": "Rochester",
          "state": "Minnesota"
        },
        {
          "city": "Huston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03558984"
    }
  ]
}