{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Sweet-cooling",
    "query": {
      "intervention": "Sweet-cooling"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 7,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-03T12:03:08.082Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT05432830",
      "title": "Sex Differences in E-cig Perception: Study 1",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Nicotine Addiction",
        "E-Cig Use",
        "Cigarette Smoking",
        "Sex Differences"
      ],
      "interventions": [
        {
          "name": "E-liquid Flavor 1",
          "type": "OTHER"
        },
        {
          "name": "E-liquid Flavor 2",
          "type": "OTHER"
        },
        {
          "name": "E-liquid Flavor 3",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Yale University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "44 Years",
        "sex": "ALL",
        "summary": "21 Years to 44 Years"
      },
      "enrollment_count": 66,
      "start_date": "2024-04-30",
      "completion_date": "2025-07-18",
      "has_results": false,
      "last_update_posted_date": "2026-01-28",
      "last_synced_at": "2026-09-03T12:03:08.082Z",
      "location_count": 1,
      "location_summary": "New Haven, Connecticut",
      "locations": [
        {
          "city": "New Haven",
          "state": "Connecticut"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05432830"
    },
    {
      "nct_id": "NCT06915428",
      "title": "Personalized Care for Prenatal Stress Reduction & Prevention of Preterm Birth (PTB) Disparities",
      "overall_status": "NOT_YET_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Preterm Birth Complication",
        "Preterm Birth",
        "Preterm Birth Recurrence",
        "Preeclampsia",
        "Preeclampsia (PE)",
        "Hypertensive Disorders of Pregnancy",
        "Support Program",
        "Stress",
        "Resilience, Psychological",
        "Empowerment, Patient",
        "Emotional Stress",
        "Pregnancy",
        "Pregnancy Complications",
        "Pregnancy Induced Hypertension",
        "Neonates and Preterm Infants",
        "Cervical Insufficiency",
        "Social Determinants of Health (SDOH)",
        "Cervical Shortening",
        "Disparities in Pregnancy Complications",
        "Disparities",
        "Prenatal Care",
        "Care Coordination"
      ],
      "interventions": [
        {
          "name": "Care coordination",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Electronic massage",
          "type": "BEHAVIORAL"
        },
        {
          "name": "support gift #1",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Support gift #2",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Support gift #3",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Support gift #4",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Additional PTBCARE+ support",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Stress reduction toolkit - Visit 1 (V1)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "PTBCARE+ mobile application (app) and website",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Sleep, meditation, and Wellness app",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Emergency low blood sugar kit",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Low dose aspirin (LDA)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Visit #2 Stress Reduction Toolkit",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of North Carolina, Chapel Hill",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "18 Years and older · Female only"
      },
      "enrollment_count": 1228,
      "start_date": "2026-08-01",
      "completion_date": "2029-01",
      "has_results": false,
      "last_update_posted_date": "2026-06-29",
      "last_synced_at": "2026-09-03T12:03:08.082Z",
      "location_count": 1,
      "location_summary": "Chapel Hill, North Carolina",
      "locations": [
        {
          "city": "Chapel Hill",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06915428"
    },
    {
      "nct_id": "NCT03719391",
      "title": "United States Pre-Market Tobacco Application Pharmacokinetics",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Nicotine Dependence",
        "Nicotine Dependence, Cigarettes",
        "Tobacco Use",
        "Tobacco Smoking"
      ],
      "interventions": [
        {
          "name": "Virginia Tobacco flavored JUUL 5% ENDS",
          "type": "OTHER"
        },
        {
          "name": "Cool Mint flavored JUUL 5% ENDS",
          "type": "OTHER"
        },
        {
          "name": "Mango flavored JUUL 5% ENDS",
          "type": "OTHER"
        },
        {
          "name": "Creme Brulee flavored JUUL 5% ENDS",
          "type": "OTHER"
        },
        {
          "name": "VUSE Solo e-cigarette",
          "type": "OTHER"
        },
        {
          "name": "Nicorette White Ice Mint 4mg nicotine polacrilex gum",
          "type": "OTHER"
        },
        {
          "name": "Usual Brand combustible cigarette",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Juul Labs, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "21 Years to 65 Years"
      },
      "enrollment_count": 67,
      "start_date": "2018-10-19",
      "completion_date": "2018-11-28",
      "has_results": false,
      "last_update_posted_date": "2021-06-14",
      "last_synced_at": "2026-09-03T12:03:08.082Z",
      "location_count": 1,
      "location_summary": "Overland Park, Kansas",
      "locations": [
        {
          "city": "Overland Park",
          "state": "Kansas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03719391"
    },
    {
      "nct_id": "NCT07594717",
      "title": "Effects of E-Cigarette Flavors on Adult E-Cigarette Users With Opioid Use Disorder",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Nicotine Use Disoder",
        "Opioid Use Disorder"
      ],
      "interventions": [
        {
          "name": "Sweet-cooling",
          "type": "DRUG"
        },
        {
          "name": "Sweet non-cooling EC flavor",
          "type": "DRUG"
        },
        {
          "name": "Tobacco flavor EC",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Prisma Health-Upstate",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "21 Years and older"
      },
      "enrollment_count": 70,
      "start_date": "2025-11-12",
      "completion_date": "2026-04-28",
      "has_results": false,
      "last_update_posted_date": "2026-08-03",
      "last_synced_at": "2026-09-03T12:03:08.082Z",
      "location_count": 1,
      "location_summary": "Greenville, South Carolina",
      "locations": [
        {
          "city": "Greenville",
          "state": "South Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07594717"
    },
    {
      "nct_id": "NCT07202039",
      "title": "Electronic Cigarettes as a Harm Reduction Strategy Among People With Opioid Use Disorder on Buprenorphine",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Tobacco-flavored EC",
        "Sweet-Cooling EC",
        "Sweet Non-cooling EC"
      ],
      "interventions": [
        {
          "name": "Brief individual counseling sessions",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Prisma Health-Upstate",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "21 Years and older"
      },
      "enrollment_count": 90,
      "start_date": "2026-04-29",
      "completion_date": "2029-06-29",
      "has_results": false,
      "last_update_posted_date": "2026-05-12",
      "last_synced_at": "2026-09-03T12:03:08.082Z",
      "location_count": 1,
      "location_summary": "Greenville, South Carolina",
      "locations": [
        {
          "city": "Greenville",
          "state": "South Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07202039"
    },
    {
      "nct_id": "NCT06506162",
      "title": "Abuse Liability and Appeal of Oral Nicotine Products",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Nicotine Dependence"
      ],
      "interventions": [
        {
          "name": "Flavor",
          "type": "OTHER"
        },
        {
          "name": "Nicotine concentration",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Southern California",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "25 Years",
        "sex": "ALL",
        "summary": "21 Years to 25 Years"
      },
      "enrollment_count": 320,
      "start_date": "2024-02-09",
      "completion_date": "2028-02-14",
      "has_results": false,
      "last_update_posted_date": "2026-07-09",
      "last_synced_at": "2026-09-03T12:03:08.082Z",
      "location_count": 1,
      "location_summary": "Los Angeles, California",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06506162"
    },
    {
      "nct_id": "NCT03634839",
      "title": "Effects of E-cigarette Flavors on Youth TCORS 2.0",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Nicotine Use Disorder"
      ],
      "interventions": [
        {
          "name": "Flavoring Agents",
          "type": "DRUG"
        },
        {
          "name": "Nicotine",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Yale University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "20 Years",
        "sex": "ALL",
        "summary": "18 Years to 20 Years"
      },
      "enrollment_count": 42,
      "start_date": "2022-11-07",
      "completion_date": "2023-07-20",
      "has_results": true,
      "last_update_posted_date": "2024-08-09",
      "last_synced_at": "2026-09-03T12:03:08.082Z",
      "location_count": 1,
      "location_summary": "New Haven, Connecticut",
      "locations": [
        {
          "city": "New Haven",
          "state": "Connecticut"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03634839"
    }
  ]
}