{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Sympathetic+Nerve+Activity&page=2",
    "query": {
      "intervention": "Sympathetic Nerve Activity",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 10,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Sympathetic+Nerve+Activity&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-09-25T12:12:17.484Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT02724241",
      "title": "E-Cigarettes and SNA",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Nicotine Dependence"
      ],
      "interventions": [
        {
          "name": "one time exposure to e-cig with nicotine",
          "type": "OTHER"
        },
        {
          "name": "One time exposure to e-cigarette without nicotine",
          "type": "OTHER"
        },
        {
          "name": "one time exposure to empty e-cigarette",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of California, Los Angeles",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "45 Years",
        "sex": "ALL",
        "summary": "21 Years to 45 Years"
      },
      "enrollment_count": 100,
      "start_date": "2015-04",
      "completion_date": "2021-12",
      "has_results": false,
      "last_update_posted_date": "2021-12-20",
      "last_synced_at": "2026-09-25T12:12:17.484Z",
      "location_count": 1,
      "location_summary": "Los Angeles, California",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02724241"
    },
    {
      "nct_id": "NCT04133701",
      "title": "Meal Timing and Blood Pressure",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Blood Pressure",
        "Neurovascular Control"
      ],
      "interventions": [
        {
          "name": "Time-Restricted Feeding",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Wisconsin, Madison",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "50 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "50 Years to 65 Years"
      },
      "enrollment_count": 34,
      "start_date": "2022-02-02",
      "completion_date": "2022-12-16",
      "has_results": false,
      "last_update_posted_date": "2023-03-22",
      "last_synced_at": "2026-09-25T12:12:17.484Z",
      "location_count": 1,
      "location_summary": "Madison, Wisconsin",
      "locations": [
        {
          "city": "Madison",
          "state": "Wisconsin"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04133701"
    },
    {
      "nct_id": "NCT01816893",
      "title": "Hypoglycemia and Autonomic Nervous System Function",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Hypoglycemia"
      ],
      "interventions": [
        {
          "name": "Hypoglycemic hyperinsulinemic clamp",
          "type": "OTHER"
        },
        {
          "name": "Euglycemic hyperinsulinemic clamp",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Brigham and Women's Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "50 Years",
        "sex": "ALL",
        "summary": "18 Years to 50 Years"
      },
      "enrollment_count": 22,
      "start_date": "2004-06-08",
      "completion_date": "2007-11-06",
      "has_results": true,
      "last_update_posted_date": "2018-04-02",
      "last_synced_at": "2026-09-25T12:12:17.484Z",
      "location_count": 2,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01816893"
    },
    {
      "nct_id": "NCT03694626",
      "title": "Objectively Diagnose and Monitor Treatment of Light Sensitivity",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Photophobia",
        "Traumatic Brain Injury",
        "Migraine"
      ],
      "interventions": [
        {
          "name": "Pupillography",
          "type": "DEVICE"
        },
        {
          "name": "Ocular Coherence Tomography (OCT)",
          "type": "DEVICE"
        },
        {
          "name": "Wrist-watch sensor device",
          "type": "DEVICE"
        },
        {
          "name": "Videography",
          "type": "DEVICE"
        },
        {
          "name": "Electrophysiology",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Randy Kardon",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 120,
      "start_date": "2019-07-11",
      "completion_date": "2028-01-01",
      "has_results": false,
      "last_update_posted_date": "2026-09-08",
      "last_synced_at": "2026-09-25T12:12:17.484Z",
      "location_count": 1,
      "location_summary": "Iowa City, Iowa",
      "locations": [
        {
          "city": "Iowa City",
          "state": "Iowa"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03694626"
    },
    {
      "nct_id": "NCT01502787",
      "title": "Comparison of Nebivolol and Metoprolol With Exercise and Angiotensin II in Hypertensive Patients",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Hypertension"
      ],
      "interventions": [
        {
          "name": "Metoprolol succinate",
          "type": "DRUG"
        },
        {
          "name": "Nebivolol",
          "type": "DRUG"
        },
        {
          "name": "Forearm blood flow",
          "type": "PROCEDURE"
        },
        {
          "name": "Microneurography",
          "type": "PROCEDURE"
        },
        {
          "name": "Rhythmic handgrip exercise",
          "type": "PROCEDURE"
        },
        {
          "name": "Lower body negative pressure",
          "type": "PROCEDURE"
        },
        {
          "name": "Angiotensin II",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG",
        "PROCEDURE"
      ],
      "sponsor": "University of Texas Southwestern Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 46,
      "start_date": "2009-04",
      "completion_date": "2013-06",
      "has_results": true,
      "last_update_posted_date": "2020-07-07",
      "last_synced_at": "2026-09-25T12:12:17.484Z",
      "location_count": 1,
      "location_summary": "Dallas, Texas",
      "locations": [
        {
          "city": "Dallas",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01502787"
    },
    {
      "nct_id": "NCT02966665",
      "title": ": Vascular Function in Health and Disease",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Chronic Obstructive Pulmonary Disease",
        "Pulmonary Artery Hypertension",
        "Heart Failure",
        "Hypertension"
      ],
      "interventions": [
        {
          "name": "Maximum Exercise Tests",
          "type": "OTHER"
        },
        {
          "name": "BH4, L-NMMA, Vitamin C, Vitamin E, α-Lipoic Acid and L-Ascorbate",
          "type": "DRUG"
        },
        {
          "name": "BQ-123",
          "type": "DRUG"
        },
        {
          "name": "Fexofenadine, Ranitidine",
          "type": "DRUG"
        },
        {
          "name": "Angiotensin-II, Valsartan",
          "type": "OTHER"
        },
        {
          "name": "Acetylcholine, Sodium Nitroprusside, Angiotensin-II, Norepinephrine, Phentolamine",
          "type": "DRUG"
        },
        {
          "name": "BQ-123, MitoQ, BH4",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "OTHER",
        "DRUG"
      ],
      "sponsor": "D. Walter Wray",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 420,
      "start_date": "2008-09",
      "completion_date": "2030-08",
      "has_results": false,
      "last_update_posted_date": "2026-09-25",
      "last_synced_at": "2026-09-25T12:12:17.484Z",
      "location_count": 1,
      "location_summary": "Salt Lake City, Utah",
      "locations": [
        {
          "city": "Salt Lake City",
          "state": "Utah"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02966665"
    },
    {
      "nct_id": "NCT03072628",
      "title": "E-cigarettes, Nicotine Inhaler, and Blood Vessel Function",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Nicotine Dependence"
      ],
      "interventions": [
        {
          "name": "e-cig with nicotine",
          "type": "OTHER"
        },
        {
          "name": "e-cig without nicotine",
          "type": "OTHER"
        },
        {
          "name": "nicotine inhaler",
          "type": "OTHER"
        },
        {
          "name": "sham control",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of California, Los Angeles",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "45 Years",
        "sex": "ALL",
        "summary": "21 Years to 45 Years"
      },
      "enrollment_count": 148,
      "start_date": "2017-01-11",
      "completion_date": "2022-12-01",
      "has_results": false,
      "last_update_posted_date": "2023-10-04",
      "last_synced_at": "2026-09-25T12:12:17.484Z",
      "location_count": 1,
      "location_summary": "Los Angeles, California",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03072628"
    },
    {
      "nct_id": "NCT02102243",
      "title": "Neural Mechanism of Aldosterone-induced Insulin Resistance",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Hypertension"
      ],
      "interventions": [
        {
          "name": "DEFINITY® infusion",
          "type": "DRUG"
        },
        {
          "name": "Human Recombinant Regular Insulin infusion",
          "type": "DRUG"
        },
        {
          "name": "Dextrose infusion",
          "type": "DRUG"
        },
        {
          "name": "Flow mediated vasodilation",
          "type": "PROCEDURE"
        },
        {
          "name": "Endothelial cell collection",
          "type": "PROCEDURE"
        },
        {
          "name": "Microvascular perfusion assessment using Definity",
          "type": "PROCEDURE"
        },
        {
          "name": "Microneurography",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "DRUG",
        "PROCEDURE"
      ],
      "sponsor": "Wanpen Vongpatanasin",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "18 Years to 75 Years"
      },
      "enrollment_count": 0,
      "start_date": "2010-11",
      "completion_date": "2025-12",
      "has_results": false,
      "last_update_posted_date": "2023-03-15",
      "last_synced_at": "2026-09-25T12:12:17.484Z",
      "location_count": 1,
      "location_summary": "Dallas, Texas",
      "locations": [
        {
          "city": "Dallas",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02102243"
    },
    {
      "nct_id": "NCT05193968",
      "title": "Hot Flashes and Neurovascular Function in Women",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Hot Flashes",
        "Menopause",
        "Vasomotor System; Labile"
      ],
      "interventions": [
        {
          "name": "Sympathoexcitatory stressors",
          "type": "OTHER"
        },
        {
          "name": "Sodium Nitroprusside",
          "type": "DRUG"
        },
        {
          "name": "Acetylcholine",
          "type": "DRUG"
        },
        {
          "name": "Terbutaline",
          "type": "DRUG"
        },
        {
          "name": "Norepinephrine",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "OTHER",
        "DRUG"
      ],
      "sponsor": "Mayo Clinic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "40 Years",
        "maximum_age": "60 Years",
        "sex": "FEMALE",
        "summary": "40 Years to 60 Years · Female only"
      },
      "enrollment_count": 120,
      "start_date": "2022-02-24",
      "completion_date": "2026-12",
      "has_results": false,
      "last_update_posted_date": "2026-06-12",
      "last_synced_at": "2026-09-25T12:12:17.484Z",
      "location_count": 1,
      "location_summary": "Rochester, Minnesota",
      "locations": [
        {
          "city": "Rochester",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05193968"
    },
    {
      "nct_id": "NCT02264262",
      "title": "Noninvasive Measurement of Sympathetic Nerve Activity in Healthy Volunteers",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Sympathetic Nerve Activity"
      ],
      "interventions": [
        {
          "name": "Physiologic maneuvers",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Cedars-Sinai Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "45 Years",
        "sex": "ALL",
        "summary": "18 Years to 45 Years"
      },
      "enrollment_count": 4,
      "start_date": "2014-10",
      "completion_date": "2017-12",
      "has_results": false,
      "last_update_posted_date": "2020-01-14",
      "last_synced_at": "2026-09-25T12:12:17.484Z",
      "location_count": 1,
      "location_summary": "Los Angeles, California",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02264262"
    }
  ]
}