{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Symptom+Assessment+Scale&page=8",
    "query": {
      "intervention": "Symptom Assessment Scale",
      "page": 8
    },
    "page_size": 10
  },
  "pagination": {
    "page": 8,
    "page_size": 10,
    "total_count": 196,
    "total_pages": 20,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Symptom+Assessment+Scale&page=9&page_size=10",
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Symptom+Assessment+Scale&page=7&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-11-15T11:45:18.377Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT07071350",
      "title": "Randomized Controlled Trial of Treatment to Optimize Heart Rate Variability for Persistent Post-Concussion Symptoms",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2",
        "PHASE3"
      ],
      "conditions": [
        "Autonomic Nervous System Disease",
        "Concussive Injury",
        "Mild Traumatic Brain Injury",
        "Post Traumatic Stress Disorder",
        "Persistent Post Concussion Syndrome"
      ],
      "interventions": [
        {
          "name": "HRV Coherence Ratio",
          "type": "OTHER"
        },
        {
          "name": "NSI",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Pittsburgh Sleep Quality Index (PSQI)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Quantitative Sleep Measures",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Patient Global Impression of Change (PGIC)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Cognitive Performance/NIH Toolbox Cognitive Battery",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Pain Interference/TBI-QoL Pain Interference Short-Form",
          "type": "OTHER"
        },
        {
          "name": "Patient Health Questionnaire-9 (PHQ-9)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "PTSD Checklist for DSM-5 (PCL-5)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "HRV Biofeedback (HRV-B)",
          "type": "OTHER"
        },
        {
          "name": "Psychoeducational (Edu) Comparator Intervention",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER",
        "BEHAVIORAL"
      ],
      "sponsor": "Virginia Commonwealth University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 148,
      "start_date": "2025-09-02",
      "completion_date": "2028-09",
      "has_results": false,
      "last_update_posted_date": "2026-09-22",
      "last_synced_at": "2026-11-15T11:45:18.377Z",
      "location_count": 1,
      "location_summary": "Richmond, Virginia",
      "locations": [
        {
          "city": "Richmond",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07071350"
    },
    {
      "nct_id": "NCT04341298",
      "title": "Use of the Avulux® Lenses as an Aid in Reducing the Impact of Migraine Headaches",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Migraine"
      ],
      "interventions": [
        {
          "name": "11-point pain scale",
          "type": "OTHER"
        },
        {
          "name": "Headache diary",
          "type": "OTHER"
        },
        {
          "name": "Avulux®",
          "type": "DEVICE"
        },
        {
          "name": "Sham Avulux®",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "OTHER",
        "DEVICE"
      ],
      "sponsor": "Avulux, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 78,
      "start_date": "2020-04-06",
      "completion_date": "2020-08-26",
      "has_results": true,
      "last_update_posted_date": "2023-01-09",
      "last_synced_at": "2026-11-15T11:45:18.377Z",
      "location_count": 3,
      "location_summary": "Minneapolis, Minnesota • Columbus, Ohio",
      "locations": [
        {
          "city": "Minneapolis",
          "state": "Minnesota"
        },
        {
          "city": "Columbus",
          "state": "Ohio"
        },
        {
          "city": "Columbus",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04341298"
    },
    {
      "nct_id": "NCT06364657",
      "title": "Differences in Corneal Structure and Function in Patients With Sjogrens vs. Non-Sjogrens Dry Eye",
      "overall_status": "TERMINATED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Sjogren's Syndrome",
        "Dry Eye",
        "Neurotrophic Keratitis"
      ],
      "interventions": [
        {
          "name": "Eye Exam",
          "type": "DIAGNOSTIC_TEST"
        }
      ],
      "intervention_types": [
        "DIAGNOSTIC_TEST"
      ],
      "sponsor": "Johns Hopkins University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 13,
      "start_date": "2024-07-01",
      "completion_date": "2024-12-19",
      "has_results": false,
      "last_update_posted_date": "2025-01-15",
      "last_synced_at": "2026-11-15T11:45:18.377Z",
      "location_count": 1,
      "location_summary": "Baltimore, Maryland",
      "locations": [
        {
          "city": "Baltimore",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06364657"
    },
    {
      "nct_id": "NCT00260572",
      "title": "Outcomes After Medical and Surgical Treatment of Gastroesophageal Reflux Disease",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Gastroesophageal Reflux Disease"
      ],
      "interventions": [
        {
          "name": "Questionnaires to evaluate QOL",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Questionnaires to evaluate heartburn and quality of life",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Questionnaire to evaluate satisfaction with treatment",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Questionnaire to evaluate presence or absence of pain",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Pittsburgh",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 2500,
      "start_date": "1999-04",
      "completion_date": "2050-12",
      "has_results": false,
      "last_update_posted_date": "2026-04-14",
      "last_synced_at": "2026-11-15T11:45:18.377Z",
      "location_count": 1,
      "location_summary": "Pittsburgh, Pennsylvania",
      "locations": [
        {
          "city": "Pittsburgh",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00260572"
    },
    {
      "nct_id": "NCT02450240",
      "title": "Latent Structure of Multi-level Assessments and Predictors of Outcomes in Psychiatric Disorders",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Depression",
        "Anxiety",
        "Eating Disorders",
        "Drug Use Disorders"
      ],
      "interventions": [
        {
          "name": "standardized diagnostic assessment",
          "type": "BEHAVIORAL"
        },
        {
          "name": "self-report questionnaires",
          "type": "BEHAVIORAL"
        },
        {
          "name": "behavioral tasks",
          "type": "BEHAVIORAL"
        },
        {
          "name": "physiological measurements",
          "type": "OTHER"
        },
        {
          "name": "structural and functional magnetic resonance imaging and EEG",
          "type": "OTHER"
        },
        {
          "name": "biomarker and microbiome assessments",
          "type": "OTHER"
        },
        {
          "name": "blood to derive induced pluripotent stem cells",
          "type": "OTHER"
        },
        {
          "name": "genetic and epigenetic assessments",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL",
        "OTHER"
      ],
      "sponsor": "Laureate Institute for Brain Research, Inc.",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "55 Years",
        "sex": "ALL",
        "summary": "18 Years to 55 Years"
      },
      "enrollment_count": 1271,
      "start_date": "2015-01",
      "completion_date": "2020-06",
      "has_results": false,
      "last_update_posted_date": "2020-07-07",
      "last_synced_at": "2026-11-15T11:45:18.377Z",
      "location_count": 1,
      "location_summary": "Tulsa, Oklahoma",
      "locations": [
        {
          "city": "Tulsa",
          "state": "Oklahoma"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02450240"
    },
    {
      "nct_id": "NCT03409120",
      "title": "Unlocking Dystonia From Parkinson's Disease With Directional DBS Technology",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Dystonia-Parkinsonism, Adult-Onset",
        "Parkinson Disease"
      ],
      "interventions": [
        {
          "name": "Boston Scientific Vercise PC IPG with directional DBS lead",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of Alabama at Birmingham",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "18 Years to 70 Years"
      },
      "enrollment_count": 38,
      "start_date": "2018-01-01",
      "completion_date": "2022-06-30",
      "has_results": true,
      "last_update_posted_date": "2022-11-10",
      "last_synced_at": "2026-11-15T11:45:18.377Z",
      "location_count": 1,
      "location_summary": "Birmingham, Alabama",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03409120"
    },
    {
      "nct_id": "NCT02990078",
      "title": "Non-invasive Measurement of Cerebrovascular Reactivity After Traumatic Brain Injury",
      "overall_status": "TERMINATED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "TBI"
      ],
      "interventions": [
        {
          "name": "Sildenafil citrate",
          "type": "DRUG"
        },
        {
          "name": "Functional Near Infared Spectroscopy",
          "type": "DEVICE"
        },
        {
          "name": "Hypercapnia Challenge",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "DEVICE",
        "OTHER"
      ],
      "sponsor": "University of Pennsylvania",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 26,
      "start_date": "2016-12",
      "completion_date": "2022-09-30",
      "has_results": false,
      "last_update_posted_date": "2022-10-13",
      "last_synced_at": "2026-11-15T11:45:18.377Z",
      "location_count": 1,
      "location_summary": "Philadelphia, Pennsylvania",
      "locations": [
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02990078"
    },
    {
      "nct_id": "NCT01307475",
      "title": "Study of Quality of Life in Freeman-Sheldon Syndrome and Related Conditions",
      "overall_status": "TERMINATED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Arthrogryposis",
        "Craniofacial Abnormalities",
        "Posttraumatic Stress Disorder",
        "Depressive Disorder"
      ],
      "interventions": [
        {
          "name": "PTSD Checklist-Specific",
          "type": "OTHER"
        },
        {
          "name": "Modified Flanagan Quality of Life Scale",
          "type": "OTHER"
        },
        {
          "name": "Center for Epidemiologic Studies Depression Scale",
          "type": "OTHER"
        },
        {
          "name": "Functional Enquiry Form",
          "type": "OTHER"
        },
        {
          "name": "Strength, Joint ROM, Girth and Length Measurements",
          "type": "OTHER"
        },
        {
          "name": "Study Physical Examination",
          "type": "OTHER"
        },
        {
          "name": "PTSD, Depression, and FSS-Focused Examination",
          "type": "OTHER"
        },
        {
          "name": "Freeman-Sheldon Specific Quality of Life Survey",
          "type": "OTHER"
        },
        {
          "name": "Lactate, Glucose, and Adenosine Triphosphate Blood Levels",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Freeman-Sheldon Research Group, Inc.",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 6,
      "start_date": "2011-02",
      "completion_date": "2017-04-01",
      "has_results": false,
      "last_update_posted_date": "2017-04-04",
      "last_synced_at": "2026-11-15T11:45:18.377Z",
      "location_count": 1,
      "location_summary": "Buckhannon, West Virginia",
      "locations": [
        {
          "city": "Buckhannon",
          "state": "West Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01307475"
    },
    {
      "nct_id": "NCT05074875",
      "title": "COVID-19 Respiratory Outcomes Registry",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Covid19"
      ],
      "interventions": [
        {
          "name": "Questionnaires and Patient Reported Outcomes (PROs)",
          "type": "OTHER"
        },
        {
          "name": "Nasal Swab COVID-19 reverse transcription polymerase chain reaction test (RT-PCR)",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Blood Samples for Biomarkers",
          "type": "GENETIC"
        },
        {
          "name": "High Resolution Computed Tomography",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Physical Exam and Vital Signs",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Medical Research Council Sum Score",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Hand Grip Strength",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Spirometry",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Diffusing Capacity of Carbon Monoxide",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "6 Minute Walk Test",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Sit to Stand (STS) Measurement",
          "type": "DIAGNOSTIC_TEST"
        }
      ],
      "intervention_types": [
        "OTHER",
        "DIAGNOSTIC_TEST",
        "GENETIC"
      ],
      "sponsor": "Weill Medical College of Cornell University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": null,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 37,
      "start_date": "2021-01-15",
      "completion_date": "2023-05-09",
      "has_results": false,
      "last_update_posted_date": "2023-07-27",
      "last_synced_at": "2026-11-15T11:45:18.377Z",
      "location_count": 4,
      "location_summary": "St Louis, Missouri • New York, New York • Houston, Texas",
      "locations": [
        {
          "city": "St Louis",
          "state": "Missouri"
        },
        {
          "city": "New York",
          "state": "New York"
        },
        {
          "city": "New York",
          "state": "New York"
        },
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05074875"
    },
    {
      "nct_id": "NCT02523378",
      "title": "Edmonton Symptom Assessment Scale: Self-Completion vs. Assisted-Completion",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Advanced Cancers"
      ],
      "interventions": [
        {
          "name": "Edmonton Symptom Assessment Scale",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Interview",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "M.D. Anderson Cancer Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 138,
      "start_date": "2015-08-13",
      "completion_date": "2020-12-03",
      "has_results": false,
      "last_update_posted_date": "2020-12-21",
      "last_synced_at": "2026-11-15T11:45:18.377Z",
      "location_count": 1,
      "location_summary": "Houston, Texas",
      "locations": [
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02523378"
    }
  ]
}