{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Symptom+Management",
    "query": {
      "intervention": "Symptom Management"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 2512,
    "total_pages": 252,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Symptom+Management&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-12T23:43:16.202Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT07809984",
      "title": "Prevention of Oral Mucositis in Adults in With Hematologic Malignancy",
      "overall_status": "NOT_YET_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Acute Leukemia",
        "Acute Myeloid Leukemia",
        "Acute Lymphoblastic Leukemia",
        "Oral Mucositis"
      ],
      "interventions": [
        {
          "name": "Aloe Vera Mouthwash",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Standard of Care",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT",
        "OTHER"
      ],
      "sponsor": "Wake Forest University Health Sciences",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 206,
      "start_date": "2026-10",
      "completion_date": "2029-02",
      "has_results": false,
      "last_update_posted_date": "2026-09-09",
      "last_synced_at": "2026-09-12T23:43:16.202Z",
      "location_count": 3,
      "location_summary": "Oak Lawn, Illinois • Park Ridge, Illinois • Milwaukee, Wisconsin",
      "locations": [
        {
          "city": "Oak Lawn",
          "state": "Illinois"
        },
        {
          "city": "Park Ridge",
          "state": "Illinois"
        },
        {
          "city": "Milwaukee",
          "state": "Wisconsin"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07809984"
    },
    {
      "nct_id": "NCT04172038",
      "title": "SMART Stepped Care Management for Low Back Pain in the Military Health System",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Low Back Pain",
        "Chronic Pain",
        "Military Personnel",
        "Veterans"
      ],
      "interventions": [
        {
          "name": "Physical Therapy",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Move 2 Health (M2H)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "MORE Mindfulness",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Brooke Army Medical Center",
      "sponsor_class": "FED",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 850,
      "start_date": "2019-12-09",
      "completion_date": "2025-07",
      "has_results": false,
      "last_update_posted_date": "2025-01-14",
      "last_synced_at": "2026-09-12T23:43:16.202Z",
      "location_count": 4,
      "location_summary": "Schofield Barracks, Hawaii • San Antonio, Texas • Tacoma, Washington",
      "locations": [
        {
          "city": "Schofield Barracks",
          "state": "Hawaii"
        },
        {
          "city": "San Antonio",
          "state": "Texas"
        },
        {
          "city": "San Antonio",
          "state": "Texas"
        },
        {
          "city": "Tacoma",
          "state": "Washington"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04172038"
    },
    {
      "nct_id": "NCT03743415",
      "title": "Caregivers' and Cancer Survivors' Psychological Distress & Symptom Management",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Cancer"
      ],
      "interventions": [
        {
          "name": "Handbook",
          "type": "BEHAVIORAL"
        },
        {
          "name": "TIP-C plus Handbook",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Arizona",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 908,
      "start_date": "2019-01-16",
      "completion_date": "2022-05-27",
      "has_results": true,
      "last_update_posted_date": "2023-11-29",
      "last_synced_at": "2026-09-12T23:43:16.202Z",
      "location_count": 1,
      "location_summary": "Tucson, Arizona",
      "locations": [
        {
          "city": "Tucson",
          "state": "Arizona"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03743415"
    },
    {
      "nct_id": "NCT04063618",
      "title": "Reduction of Concussion Symptoms Through the Use of Osteopathic Manipulative Therapy",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Concussion, Brain"
      ],
      "interventions": [
        {
          "name": "Osteopathic Manipulative Therapy",
          "type": "PROCEDURE"
        },
        {
          "name": "Standard of Care Concussion Treatment",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Matthew T. Mcelroy, DO",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "24 Years",
        "sex": "ALL",
        "summary": "Up to 24 Years"
      },
      "enrollment_count": 1,
      "start_date": "2019-12-03",
      "completion_date": "2021-11-16",
      "has_results": false,
      "last_update_posted_date": "2023-03-31",
      "last_synced_at": "2026-09-12T23:43:16.202Z",
      "location_count": 1,
      "location_summary": "Danville, Pennsylvania",
      "locations": [
        {
          "city": "Danville",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04063618"
    },
    {
      "nct_id": "NCT02226497",
      "title": "Telemonitoring Device in Managing Outpatient Care of Patients With Myelodysplastic Syndrome or Acute Myeloid Leukemia After Intensive Chemotherapy",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Acute Myeloid Leukemia",
        "Myelodysplastic Syndrome"
      ],
      "interventions": [
        {
          "name": "Health Telemonitoring",
          "type": "DEVICE"
        },
        {
          "name": "Quality-of-Life Assessment",
          "type": "OTHER"
        },
        {
          "name": "Questionnaire Administration",
          "type": "OTHER"
        },
        {
          "name": "Supportive Care",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "OTHER",
        "PROCEDURE"
      ],
      "sponsor": "Fred Hutchinson Cancer Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "18 Years to 75 Years"
      },
      "enrollment_count": 24,
      "start_date": "2015-01-09",
      "completion_date": "2018-08-30",
      "has_results": false,
      "last_update_posted_date": "2020-01-10",
      "last_synced_at": "2026-09-12T23:43:16.202Z",
      "location_count": 1,
      "location_summary": "Seattle, Washington",
      "locations": [
        {
          "city": "Seattle",
          "state": "Washington"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02226497"
    },
    {
      "nct_id": "NCT03873610",
      "title": "Resiliency Training in Adolescents With NF1 and NF2",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Neurofibromatoses"
      ],
      "interventions": [
        {
          "name": "Stress and Symptom Management Program 1",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Stress and Symptom Management Program 2",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Massachusetts General Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "12 Years",
        "maximum_age": "17 Years",
        "sex": "ALL",
        "summary": "12 Years to 17 Years"
      },
      "enrollment_count": 196,
      "start_date": "2019-12-15",
      "completion_date": "2026-02-20",
      "has_results": false,
      "last_update_posted_date": "2026-06-11",
      "last_synced_at": "2026-09-12T23:43:16.202Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03873610"
    },
    {
      "nct_id": "NCT04722835",
      "title": "Lung Macrophage Populations and Functions in Chronic Obstructive Pulmonary Disease (COPD)-Susceptible Smokers",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Copd",
        "Smoking",
        "Tobacco Use"
      ],
      "interventions": [
        {
          "name": "Bronchoscopy with Bronchoalveolar Lavage (BAL)",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "University of California, San Francisco",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "40 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "40 Years to 75 Years"
      },
      "enrollment_count": 40,
      "start_date": "2021-03-01",
      "completion_date": "2030-12-31",
      "has_results": false,
      "last_update_posted_date": "2026-06-04",
      "last_synced_at": "2026-09-12T23:43:16.202Z",
      "location_count": 3,
      "location_summary": "San Francisco, California",
      "locations": [
        {
          "city": "San Francisco",
          "state": "California"
        },
        {
          "city": "San Francisco",
          "state": "California"
        },
        {
          "city": "San Francisco",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04722835"
    },
    {
      "nct_id": "NCT01832155",
      "title": "Yoga for Managing Knee Osteoarthritis in Older Women: a Feasibility Study",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Osteoarthritis, Knee",
        "Quality of Life",
        "Poor Quality Sleep",
        "Physical Impairment"
      ],
      "interventions": [
        {
          "name": "Hatha Yoga",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Minnesota",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "65 Years",
        "maximum_age": "86 Years",
        "sex": "FEMALE",
        "summary": "65 Years to 86 Years · Female only"
      },
      "enrollment_count": 36,
      "start_date": "2011-01",
      "completion_date": "2011-12",
      "has_results": true,
      "last_update_posted_date": "2019-11-01",
      "last_synced_at": "2026-09-12T23:43:16.202Z",
      "location_count": 1,
      "location_summary": "Minneapolis, Minnesota",
      "locations": [
        {
          "city": "Minneapolis",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01832155"
    },
    {
      "nct_id": "NCT06013176",
      "title": "Behavioral Economic Strategies to Improve PRO Adherence",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Cancer"
      ],
      "interventions": [
        {
          "name": "Encounter-based PRO monitoring",
          "type": "OTHER"
        },
        {
          "name": "Remote PRO monitoring",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Abramson Cancer Center at Penn Medicine",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 476,
      "start_date": "2023-12-04",
      "completion_date": "2024-09-04",
      "has_results": true,
      "last_update_posted_date": "2025-12-29",
      "last_synced_at": "2026-09-12T23:43:16.202Z",
      "location_count": 2,
      "location_summary": "Plainsboro, New Jersey • Philadelphia, Pennsylvania",
      "locations": [
        {
          "city": "Plainsboro",
          "state": "New Jersey"
        },
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06013176"
    },
    {
      "nct_id": "NCT03724097",
      "title": "Identification of Molecular Biomarkers for Cancer Target Therapy Efficacy",
      "overall_status": "UNKNOWN",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Cancer"
      ],
      "interventions": [
        {
          "name": "RNA sequencing",
          "type": "OTHER"
        },
        {
          "name": "Transcriptome analysis",
          "type": "OTHER"
        },
        {
          "name": "target drug with the score above 0,1",
          "type": "DRUG"
        },
        {
          "name": "target drug with the score equal or below 0,1",
          "type": "DRUG"
        },
        {
          "name": "non-target drug",
          "type": "DRUG"
        },
        {
          "name": "palliative care",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "OTHER",
        "DRUG"
      ],
      "sponsor": "OmicsWay Corp.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "18 Years to 80 Years"
      },
      "enrollment_count": 200,
      "start_date": "2017-10-17",
      "completion_date": "2022-11-01",
      "has_results": false,
      "last_update_posted_date": "2021-09-14",
      "last_synced_at": "2026-09-12T23:43:16.202Z",
      "location_count": 1,
      "location_summary": "Walnut, California",
      "locations": [
        {
          "city": "Walnut",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03724097"
    }
  ]
}