{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Symptom-based+adjustment&page=3",
    "query": {
      "intervention": "Symptom-based adjustment",
      "page": 3
    },
    "page_size": 10
  },
  "pagination": {
    "page": 3,
    "page_size": 10,
    "total_count": 60,
    "total_pages": 6,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Symptom-based+adjustment&page=4&page_size=10",
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Symptom-based+adjustment&page=2&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-11-15T08:12:14.848Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT06770777",
      "title": "Development And Evaluation of An Adaptive Web-Based Intervention for COPD",
      "overall_status": "NOT_YET_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "COPD (Chronic Obstructive Pulmonary Disease)"
      ],
      "interventions": [
        {
          "name": "Tiered whole health support for people living with COPD",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Colorado, Denver",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "89 Years",
        "sex": "ALL",
        "summary": "18 Years to 89 Years"
      },
      "enrollment_count": 60,
      "start_date": "2025-12",
      "completion_date": "2028-11",
      "has_results": false,
      "last_update_posted_date": "2025-05-08",
      "last_synced_at": "2026-11-15T08:12:14.848Z",
      "location_count": 1,
      "location_summary": "Aurora, Colorado",
      "locations": [
        {
          "city": "Aurora",
          "state": "Colorado"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06770777"
    },
    {
      "nct_id": "NCT05966532",
      "title": "Emotional Cognition: Establishing Constructs and Neural-Behavioral Mechanisms in Older Adults With Depression",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Major Depressive Disorder (MDD)",
        "Healthy Adult Volunteer"
      ],
      "interventions": [
        {
          "name": "Hot Cognitive Task",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Cold cognitive tasks",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Structural magnetic resonance imaging (sMRI)",
          "type": "OTHER"
        },
        {
          "name": "Magnetoencephalography imaging (MEG)",
          "type": "OTHER"
        },
        {
          "name": "four self-report forms per the requirement of the NIH Common Data Elements project",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Four self-report measures to assess interpersonal functioning",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Clinical assessments",
          "type": "BEHAVIORAL"
        },
        {
          "name": "ATHF",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL",
        "OTHER"
      ],
      "sponsor": "University of Texas Southwestern Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "21 Years to 80 Years"
      },
      "enrollment_count": 276,
      "start_date": "2023-12-11",
      "completion_date": "2027-08-31",
      "has_results": false,
      "last_update_posted_date": "2026-07-30",
      "last_synced_at": "2026-11-15T08:12:14.848Z",
      "location_count": 2,
      "location_summary": "Arlington, Texas • Dallas, Texas",
      "locations": [
        {
          "city": "Arlington",
          "state": "Texas"
        },
        {
          "city": "Dallas",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05966532"
    },
    {
      "nct_id": "NCT00979108",
      "title": "The Value of Traction in the Treatment of Cervical Radiculopathy",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Radiculopathy",
        "Neck Pain",
        "Spinal Diseases",
        "Musculoskeletal Diseases",
        "Neuromuscular Diseases",
        "Intervertebral Disk Displacement"
      ],
      "interventions": [
        {
          "name": "Physical therapy rehabilitation",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Intermountain Health Care, Inc.",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "18 Years to 70 Years"
      },
      "enrollment_count": 86,
      "start_date": "2009-07",
      "completion_date": "2013-01",
      "has_results": false,
      "last_update_posted_date": "2014-11-17",
      "last_synced_at": "2026-11-15T08:12:14.848Z",
      "location_count": 2,
      "location_summary": "Lackland Air Force Base, Texas • Salt Lake City, Utah",
      "locations": [
        {
          "city": "Lackland Air Force Base",
          "state": "Texas"
        },
        {
          "city": "Salt Lake City",
          "state": "Utah"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00979108"
    },
    {
      "nct_id": "NCT00411463",
      "title": "Psychotherapy for Bipolar II Depression, Pilot Study, Phase II",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2",
        "PHASE3"
      ],
      "conditions": [
        "Bipolar II Disorder"
      ],
      "interventions": [
        {
          "name": "Interpersonal and Social Rhythm Therapy (IPSRT-BPII)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Seroquel",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL",
        "DRUG"
      ],
      "sponsor": "University of Pittsburgh",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 25,
      "start_date": "2006-12",
      "completion_date": "2010-09",
      "has_results": true,
      "last_update_posted_date": "2017-05-30",
      "last_synced_at": "2026-11-15T08:12:14.848Z",
      "location_count": 1,
      "location_summary": "Pittsburgh, Pennsylvania",
      "locations": [
        {
          "city": "Pittsburgh",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00411463"
    },
    {
      "nct_id": "NCT00959426",
      "title": "A Multiple Dose Study Of PF-04620110 In Overweight And Obese, Otherwise Healthy Volunteers",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Obesity",
        "Overweight",
        "Healthy"
      ],
      "interventions": [
        {
          "name": "PF-04620110",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Pfizer",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "55 Years",
        "sex": "ALL",
        "summary": "18 Years to 55 Years"
      },
      "enrollment_count": 71,
      "start_date": "2009-08",
      "completion_date": "2010-05",
      "has_results": false,
      "last_update_posted_date": "2010-06-07",
      "last_synced_at": "2026-11-15T08:12:14.848Z",
      "location_count": 1,
      "location_summary": "New Haven, Connecticut",
      "locations": [
        {
          "city": "New Haven",
          "state": "Connecticut"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00959426"
    },
    {
      "nct_id": "NCT02466685",
      "title": "Testing the Ability of JNJ-18038683 to Improve Cognition and Reduce Depressive Symptoms in Stable Bipolar Patients",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Bipolar Disorder"
      ],
      "interventions": [
        {
          "name": "JNJ-18038683",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Herbert Meltzer",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "60 Years",
        "sex": "ALL",
        "summary": "18 Years to 60 Years"
      },
      "enrollment_count": 60,
      "start_date": "2015-09",
      "completion_date": "2022-12",
      "has_results": true,
      "last_update_posted_date": "2023-11-14",
      "last_synced_at": "2026-11-15T08:12:14.848Z",
      "location_count": 1,
      "location_summary": "Chicago, Illinois",
      "locations": [
        {
          "city": "Chicago",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02466685"
    },
    {
      "nct_id": "NCT00518973",
      "title": "Trial of Quetiapine in Anorexia Nervosa",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Anorexia Nervosa"
      ],
      "interventions": [
        {
          "name": "Quetiapine",
          "type": "DRUG"
        },
        {
          "name": "Placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of California, San Diego",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 21,
      "start_date": "2006-07",
      "completion_date": "2010-05",
      "has_results": true,
      "last_update_posted_date": "2019-07-17",
      "last_synced_at": "2026-11-15T08:12:14.848Z",
      "location_count": 1,
      "location_summary": "San Diego, California",
      "locations": [
        {
          "city": "San Diego",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00518973"
    },
    {
      "nct_id": "NCT04986670",
      "title": "NutriCare Plus a Medically Tailored Meal Intervention Among Patients With Lung Cancer",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Lung Cancer, Small Cell",
        "Lung Cancer Metastatic",
        "Lung Cancer Recurrent",
        "Treatment Side Effects",
        "Lung Cancer, Non-small Cell",
        "Nutritional Imbalance"
      ],
      "interventions": [
        {
          "name": "Nutritional Counseling",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Medically Tailored Meals (MTMs)",
          "type": "OTHER"
        },
        {
          "name": "Nutrition Prescription",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Nutrition Assessment",
          "type": "OTHER"
        },
        {
          "name": "Nutrition Toolkit",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Monthly Emails",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL",
        "OTHER"
      ],
      "sponsor": "Tufts University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "100 Years",
        "sex": "ALL",
        "summary": "18 Years to 100 Years"
      },
      "enrollment_count": 299,
      "start_date": "2020-11-24",
      "completion_date": "2026-12-31",
      "has_results": false,
      "last_update_posted_date": "2025-09-30",
      "last_synced_at": "2026-11-15T08:12:14.848Z",
      "location_count": 4,
      "location_summary": "Boston, Massachusetts • Columbus, Ohio • Philadelphia, Pennsylvania + 1 more",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "Columbus",
          "state": "Ohio"
        },
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        },
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04986670"
    },
    {
      "nct_id": "NCT04360681",
      "title": "Lofexidine Combined With Buprenorphine for Reducing Symptoms of PTSD and OU Relapse in Veterans",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Post Traumatic Stress Disorder",
        "Opioid-use Disorder"
      ],
      "interventions": [
        {
          "name": "Lofexidine",
          "type": "DRUG"
        },
        {
          "name": "Placebo oral tablet",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Pharmacotherapies for Alcohol and Substance Use Disorders Alliance",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "18 Years to 70 Years"
      },
      "enrollment_count": 84,
      "start_date": "2021-03-09",
      "completion_date": "2026-01-29",
      "has_results": false,
      "last_update_posted_date": "2026-05-08",
      "last_synced_at": "2026-11-15T08:12:14.848Z",
      "location_count": 2,
      "location_summary": "Houston, Texas • San Antonio, Texas",
      "locations": [
        {
          "city": "Houston",
          "state": "Texas"
        },
        {
          "city": "San Antonio",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04360681"
    },
    {
      "nct_id": "NCT03456856",
      "title": "A Study of Ivabradine in African-American/ Black Subjects With Heart Failure and Left Ventricular Systolic Dysfunction.",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Heart Failure (HF)"
      ],
      "interventions": [
        {
          "name": "Ivabradine",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Amgen",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "100 Years",
        "sex": "ALL",
        "summary": "18 Years to 100 Years"
      },
      "enrollment_count": 30,
      "start_date": "2017-09-28",
      "completion_date": "2019-05-20",
      "has_results": true,
      "last_update_posted_date": "2021-10-28",
      "last_synced_at": "2026-11-15T08:12:14.848Z",
      "location_count": 3,
      "location_summary": "Wilmington, Delaware • Detroit, Michigan • Buffalo, New York",
      "locations": [
        {
          "city": "Wilmington",
          "state": "Delaware"
        },
        {
          "city": "Detroit",
          "state": "Michigan"
        },
        {
          "city": "Buffalo",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03456856"
    }
  ]
}