{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Synovial+Fluid+Aspiration",
    "query": {
      "intervention": "Synovial Fluid Aspiration"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 6,
    "total_pages": 1,
    "next_page_url": null,
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-27T11:11:23.489Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT05465382",
      "title": "Effect of Early Saline Lavage on Synovial Fluid Composition Following Intra Articular Ankle Fractures",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Intra-Articular Fractures"
      ],
      "interventions": [
        {
          "name": "Saline Lavage",
          "type": "DEVICE"
        },
        {
          "name": "No intra-articular saline lavage",
          "type": "OTHER"
        },
        {
          "name": "Lidocaine - intra-articular injection",
          "type": "DRUG"
        },
        {
          "name": "Synovial Fluid Aspiration",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "OTHER",
        "DRUG"
      ],
      "sponsor": "Duke University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 41,
      "start_date": "2022-07-22",
      "completion_date": "2024-05-07",
      "has_results": true,
      "last_update_posted_date": "2026-04-14",
      "last_synced_at": "2026-09-27T11:11:23.489Z",
      "location_count": 1,
      "location_summary": "Durham, North Carolina",
      "locations": [
        {
          "city": "Durham",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05465382"
    },
    {
      "nct_id": "NCT02481869",
      "title": "Platelet Rich Plasma Injection in Pilon Fractures",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Fracture"
      ],
      "interventions": [
        {
          "name": "Arthrocentesis/PRP",
          "type": "BIOLOGICAL"
        },
        {
          "name": "Arthrocentesis/Saline",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL",
        "DRUG"
      ],
      "sponsor": "University of Missouri-Columbia",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 11,
      "start_date": "2015-06",
      "completion_date": "2019-11",
      "has_results": true,
      "last_update_posted_date": "2021-02-05",
      "last_synced_at": "2026-09-27T11:11:23.489Z",
      "location_count": 1,
      "location_summary": "Columbia, Missouri",
      "locations": [
        {
          "city": "Columbia",
          "state": "Missouri"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02481869"
    },
    {
      "nct_id": "NCT03704766",
      "title": "Alpha-Defensin and Synovial Proteins to Improve Detection of Pediatric Septic Arthritis",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Joint Infection",
        "Infection of Hip Joint (Disorder)",
        "Infection of Shoulder Joint",
        "Septic Arthritis"
      ],
      "interventions": [
        {
          "name": "Synovial Alpha-defensin assay",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Synovial Neutrophil elastase assay",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Synovial lactate assay",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Synovial C-reactive Protein (CRP)",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Synovial Staphylococcus spp antigen panel",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Synovial Candida spp antigen panel",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Synovial Enterococcus faecalis assay",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Synovial bacterial culture by BacT/Alert",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Synovial Cell count + differential (CBC)",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Synovial Gram Stain",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Synovial Leukocyte Esterase Test Strips",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Synovial PCR for Kingella kingae",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Serum Cell count + differential (CBC)",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Serum erythrocyte sedimentation rate (ESR)",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Serum C-reactive Protein (CRP)",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Serum D-dimer",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Serum Procalcitonin",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Blood Cultures",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Optional blood testing per standard of care (ASO, anti-strep, ANA, anti-DS-DNA, HLA-B27, RF, Lyme and other inflammatory/ rheumatologic markers )",
          "type": "DIAGNOSTIC_TEST"
        }
      ],
      "intervention_types": [
        "DIAGNOSTIC_TEST"
      ],
      "sponsor": "Hospital for Special Surgery, New York",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": "17 Years",
        "sex": "ALL",
        "summary": "Up to 17 Years"
      },
      "enrollment_count": 442,
      "start_date": "2016-06-28",
      "completion_date": "2027-01",
      "has_results": false,
      "last_update_posted_date": "2026-07-29",
      "last_synced_at": "2026-09-27T11:11:23.489Z",
      "location_count": 3,
      "location_summary": "Atlanta, Georgia • New York, New York • Collierville, Tennessee",
      "locations": [
        {
          "city": "Atlanta",
          "state": "Georgia"
        },
        {
          "city": "New York",
          "state": "New York"
        },
        {
          "city": "Collierville",
          "state": "Tennessee"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03704766"
    },
    {
      "nct_id": "NCT01209585",
      "title": "A Study to Evaluate BioMarkers in Blood Samples in Subjects With Rheumatoid Arthritis",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Arthritis"
      ],
      "interventions": [
        {
          "name": "Blood samples",
          "type": "OTHER"
        },
        {
          "name": "Synovial fluid aspiration",
          "type": "OTHER"
        },
        {
          "name": "Synovial tissue sample",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "MedImmune LLC",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "18 Years to 75 Years"
      },
      "enrollment_count": 23,
      "start_date": "2011-03",
      "completion_date": "2013-03",
      "has_results": false,
      "last_update_posted_date": "2013-07-25",
      "last_synced_at": "2026-09-27T11:11:23.489Z",
      "location_count": 3,
      "location_summary": "Frederick, Maryland • Wyomissing, Pennsylvania • Jackson, Tennessee",
      "locations": [
        {
          "city": "Frederick",
          "state": "Maryland"
        },
        {
          "city": "Wyomissing",
          "state": "Pennsylvania"
        },
        {
          "city": "Jackson",
          "state": "Tennessee"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01209585"
    },
    {
      "nct_id": "NCT02878941",
      "title": "Synovial Fluid Analysis of Intraarticular Elbow Fracture",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Elbow Fracture",
        "Joint Contracture"
      ],
      "interventions": [
        {
          "name": "Synovial Fluid Analysis",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Duke University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 12,
      "start_date": "2017-05-01",
      "completion_date": "2020-05-17",
      "has_results": false,
      "last_update_posted_date": "2020-07-07",
      "last_synced_at": "2026-09-27T11:11:23.489Z",
      "location_count": 1,
      "location_summary": "Durham, North Carolina",
      "locations": [
        {
          "city": "Durham",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02878941"
    },
    {
      "nct_id": "NCT01514643",
      "title": "Inflammatory Response Following Intraarticular Fracture",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Intraarticular Fracture and Post-traumatic Osteoarthritis"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "University of Utah",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "60 Years",
        "sex": "ALL",
        "summary": "18 Years to 60 Years"
      },
      "enrollment_count": 60,
      "start_date": "2011-10",
      "completion_date": "2028-12",
      "has_results": false,
      "last_update_posted_date": "2026-04-29",
      "last_synced_at": "2026-09-27T11:11:23.489Z",
      "location_count": 1,
      "location_summary": "Salt Lake City, Utah",
      "locations": [
        {
          "city": "Salt Lake City",
          "state": "Utah"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01514643"
    }
  ]
}