{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=T-wave+Alternans",
    "query": {
      "intervention": "T-wave Alternans"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 14,
    "total_pages": 2,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=T-wave+Alternans&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-11T09:53:46.280Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT00006501",
      "title": "Prognostic Significance of T Wave Alternans",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Heart Diseases",
        "Ventricular Arrhythmia",
        "Ventricular Fibrillation",
        "Death, Sudden, Cardiac",
        "Heart Arrest"
      ],
      "interventions": [
        {
          "name": "ECG",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Columbia University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 549,
      "start_date": "2003-01",
      "completion_date": "2012-02",
      "has_results": false,
      "last_update_posted_date": "2015-12-23",
      "last_synced_at": "2026-09-11T09:53:46.280Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00006501"
    },
    {
      "nct_id": "NCT00669682",
      "title": "T-wave Alternans and Intrathoracic Impedance Measurements",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Congestive Heart Failure",
        "Arrhythmias"
      ],
      "interventions": [
        {
          "name": "Congestive heart failure",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Columbia University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 9,
      "start_date": "2008-08",
      "completion_date": "2012-04",
      "has_results": true,
      "last_update_posted_date": "2013-04-19",
      "last_synced_at": "2026-09-11T09:53:46.280Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00669682"
    },
    {
      "nct_id": "NCT00305240",
      "title": "MASTER I - Microvolt T Wave Alternans Testing for Risk Stratification of Post MI Patients",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Myocardial Infarction",
        "Arrhythmia, Ventricular",
        "Ischemic Cardiomyopathy"
      ],
      "interventions": [
        {
          "name": "T Wave Alternans Test",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Medtronic Cardiac Rhythm and Heart Failure",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 656,
      "start_date": "2003-10",
      "completion_date": "2007-02",
      "has_results": false,
      "last_update_posted_date": "2008-02-13",
      "last_synced_at": "2026-09-11T09:53:46.280Z",
      "location_count": 47,
      "location_summary": "Mobile, Alabama • Phoenix, Arizona • Walnut Creek, California + 44 more",
      "locations": [
        {
          "city": "Mobile",
          "state": "Alabama"
        },
        {
          "city": "Phoenix",
          "state": "Arizona"
        },
        {
          "city": "Walnut Creek",
          "state": "California"
        },
        {
          "city": "Denver",
          "state": "Colorado"
        },
        {
          "city": "Hartford",
          "state": "Connecticut"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00305240"
    },
    {
      "nct_id": "NCT00669552",
      "title": "Intracardiac T-wave Alternans and Ischemia",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Ischemia"
      ],
      "interventions": [
        {
          "name": "Percutaneous coronary intervention",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Columbia University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 11,
      "start_date": "2008-08",
      "completion_date": "2012-07",
      "has_results": true,
      "last_update_posted_date": "2013-04-19",
      "last_synced_at": "2026-09-11T09:53:46.280Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00669552"
    },
    {
      "nct_id": "NCT00305214",
      "title": "MASTER II - Microvolt T Wave Alternans Testing for Risk Stratification of Post MI Patients",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Myocardial Infarction",
        "Arrhythmia, Ventricular",
        "Ischemic Cardiomyopathy"
      ],
      "interventions": [
        {
          "name": "T Wave Alternans Test",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Medtronic Cardiac Rhythm and Heart Failure",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 405,
      "start_date": "2003-10",
      "completion_date": "2007-02",
      "has_results": false,
      "last_update_posted_date": "2008-02-13",
      "last_synced_at": "2026-09-11T09:53:46.280Z",
      "location_count": 47,
      "location_summary": "Mobile, Alabama • Phoenix, Arizona • Walnut Creek, California + 44 more",
      "locations": [
        {
          "city": "Mobile",
          "state": "Alabama"
        },
        {
          "city": "Phoenix",
          "state": "Arizona"
        },
        {
          "city": "Walnut Creek",
          "state": "California"
        },
        {
          "city": "Denver",
          "state": "Colorado"
        },
        {
          "city": "Hartford",
          "state": "Connecticut"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00305214"
    },
    {
      "nct_id": "NCT01856400",
      "title": "Ventricular Arrhythmias in Uremic Cardiomyopathy",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Cardiomyopathy"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Northwell Health",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 36,
      "start_date": "2010-01",
      "completion_date": "2013-08",
      "has_results": false,
      "last_update_posted_date": "2014-02-03",
      "last_synced_at": "2026-09-11T09:53:46.280Z",
      "location_count": 1,
      "location_summary": "Staten Island, New York",
      "locations": [
        {
          "city": "Staten Island",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01856400"
    },
    {
      "nct_id": "NCT01137513",
      "title": "T-Wave Alternans in Patients With Suspected Acute Coronary Syndrome",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Chest Pain",
        "Acute Coronary Syndrome",
        "Acute Myocardial Infarction"
      ],
      "interventions": [
        {
          "name": "Observational Measurement of T-wave Alternans",
          "type": "DEVICE"
        },
        {
          "name": "T-wave Alternans",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Loma Linda University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 252,
      "start_date": "2010-07",
      "completion_date": "2013-12",
      "has_results": false,
      "last_update_posted_date": "2014-05-26",
      "last_synced_at": "2026-09-11T09:53:46.280Z",
      "location_count": 1,
      "location_summary": "Loma Linda, California",
      "locations": [
        {
          "city": "Loma Linda",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01137513"
    },
    {
      "nct_id": "NCT00621426",
      "title": "T-Wave Alternans in Dialysis Patients",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Sudden Cardiac Death",
        "End Stage Renal Disease"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Northwestern University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "90 Years",
        "sex": "ALL",
        "summary": "18 Years to 90 Years"
      },
      "enrollment_count": 40,
      "start_date": "2007-04",
      "completion_date": "2008-05",
      "has_results": false,
      "last_update_posted_date": "2015-03-12",
      "last_synced_at": "2026-09-11T09:53:46.280Z",
      "location_count": 1,
      "location_summary": "Chicago, Illinois",
      "locations": [
        {
          "city": "Chicago",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00621426"
    },
    {
      "nct_id": "NCT00589849",
      "title": "T-Wave Alternans in Acute Myocardial Infarction: An Evaluation of the Time of Testing on Its Prognostic Accuracy",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Myocardial Infarction",
        "Arrhythmias"
      ],
      "interventions": [
        {
          "name": "T-wave Alternans",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Creighton University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "19 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "19 Years and older"
      },
      "enrollment_count": 32,
      "start_date": "2006-05",
      "completion_date": "2011-05",
      "has_results": true,
      "last_update_posted_date": "2011-10-05",
      "last_synced_at": "2026-09-11T09:53:46.280Z",
      "location_count": 1,
      "location_summary": "Omaha, Nebraska",
      "locations": [
        {
          "city": "Omaha",
          "state": "Nebraska"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00589849"
    },
    {
      "nct_id": "NCT01174797",
      "title": "Evaluation of Microvolt T-Wave Alternans(MTWA) Testing for the Detection of Active Ischemia",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Coronary Artery Disease"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "Cambridge Heart Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 186,
      "start_date": "2010-06",
      "completion_date": "2013-05",
      "has_results": false,
      "last_update_posted_date": "2013-05-27",
      "last_synced_at": "2026-09-11T09:53:46.280Z",
      "location_count": 2,
      "location_summary": "Bridgeport, Connecticut • Tomball, Texas",
      "locations": [
        {
          "city": "Bridgeport",
          "state": "Connecticut"
        },
        {
          "city": "Tomball",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01174797"
    }
  ]
}