{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=THS+use", "query": { "intervention": "THS use" }, "page_size": 10 }, "pagination": { "page": 1, "page_size": 10, "total_count": 7, "total_pages": 1, "next_page_url": null, "previous_page_url": null }, "source": "remote", "last_synced_at": "2026-09-03T06:19:19.921Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT01989156", "title": "Reduced Exposure Study Using THS 2.2 Menthol With 5 Days in a Confinement Setting Followed by 86 Days in an Ambulatory Setting", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Smoking" ], "interventions": [ { "name": "THS 2.2 Menthol (mTHS 2.2)", "type": "OTHER" }, { "name": "Menthol Conventional Cigarette (mCC)", "type": "OTHER" }, { "name": "Smoking Abstinence (SA)", "type": "OTHER" } ], "intervention_types": [ "OTHER" ], "sponsor": "Philip Morris Products S.A.", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "22 Years", "maximum_age": null, "sex": "ALL", "summary": "22 Years and older" }, "enrollment_count": 160, "start_date": "2013-12", "completion_date": "2015-05", "has_results": true, "last_update_posted_date": "2020-03-24", "last_synced_at": "2026-09-03T06:19:19.921Z", "location_count": 2, "location_summary": "Daytona Beach, Florida • Dallas, Texas", "locations": [ { "city": "Daytona Beach", "state": "Florida" }, { "city": "Dallas", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT01989156" }, { "nct_id": "NCT07108166", "title": "Symptoms and Functions in Patients With COPD and Chronic Bronchitis Switching From CIG to THS", "overall_status": "ACTIVE_NOT_RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "COPD", "Smoking", "Tobacco Use" ], "interventions": [ { "name": "Cigarette", "type": "OTHER" }, { "name": "THS", "type": "OTHER" } ], "intervention_types": [ "OTHER" ], "sponsor": "Philip Morris Products S.A.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "40 Years", "maximum_age": null, "sex": "ALL", "summary": "40 Years and older" }, "enrollment_count": 290, "start_date": "2025-04-02", "completion_date": "2026-11", "has_results": false, "last_update_posted_date": "2026-08-31", "last_synced_at": "2026-09-03T06:19:19.921Z", "location_count": 46, "location_summary": "Clearwater, Florida • Coral Gables, Florida • Davie, Florida + 24 more", "locations": [ { "city": "Clearwater", "state": "Florida" }, { "city": "Coral Gables", "state": "Florida" }, { "city": "Davie", "state": "Florida" }, { "city": "DeBary", "state": "Florida" }, { "city": "Doral", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT07108166" }, { "nct_id": "NCT02649556", "title": "A 26-week Extension of the ZRHR-ERS-09-US Study Evaluating Biological and Functional Changes in Healthy Smokers After Switching to THS 2.2", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Smoking" ], "interventions": [ { "name": "THS 2.2", "type": "OTHER" }, { "name": "CC", "type": "OTHER" } ], "intervention_types": [ "OTHER" ], "sponsor": "Philip Morris Products S.A.", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "30 Years", "maximum_age": null, "sex": "ALL", "summary": "30 Years and older" }, "enrollment_count": 672, "start_date": "2015-09-30", "completion_date": "2017-12-20", "has_results": true, "last_update_posted_date": "2020-12-04", "last_synced_at": "2026-09-03T06:19:19.921Z", "location_count": 19, "location_summary": "Tempe, Arizona • Clearwater, Florida • Daytona Beach, Florida + 16 more", "locations": [ { "city": "Tempe", "state": "Arizona" }, { "city": "Clearwater", "state": "Florida" }, { "city": "Daytona Beach", "state": "Florida" }, { "city": "Orlando", "state": "Florida" }, { "city": "Tampa", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT02649556" }, { "nct_id": "NCT07049757", "title": "Healthy Family Project: Tobacco Use and Smoke Exposure in Asian American Communities", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Tobacco-Related Carcinoma", "Smoking Cessation" ], "interventions": [ { "name": "Smoking cessation education", "type": "OTHER" }, { "name": "Survey Administration", "type": "BEHAVIORAL" }, { "name": "Telephone-Based Intervention", "type": "BEHAVIORAL" }, { "name": "Urine Specimen Collection", "type": "PROCEDURE" }, { "name": "Silicone Wrist Band", "type": "OTHER" }, { "name": "Interview", "type": "OTHER" }, { "name": "Focus Group", "type": "OTHER" } ], "intervention_types": [ "OTHER", "BEHAVIORAL", "PROCEDURE" ], "sponsor": "University of California, San Francisco", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 760, "start_date": "2026-03-23", "completion_date": "2028-09-30", "has_results": false, "last_update_posted_date": "2026-06-04", "last_synced_at": "2026-09-03T06:19:19.921Z", "location_count": 1, "location_summary": "San Francisco, California", "locations": [ { "city": "San Francisco", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT07049757" }, { "nct_id": "NCT05569005", "title": "Effect of Switching From Cigarette Smoking to THS on Disease Progression in Mild to Moderate COPD Subjects With Chronic Bronchitis Symptoms.", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "COPD", "Smoking", "Tobacco Use" ], "interventions": [ { "name": "THS use", "type": "OTHER" }, { "name": "Cigarette", "type": "OTHER" }, { "name": "Smoking Abstinence", "type": "OTHER" } ], "intervention_types": [ "OTHER" ], "sponsor": "Philip Morris Products S.A.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "35 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "35 Years to 65 Years" }, "enrollment_count": 715, "start_date": "2022-12-16", "completion_date": "2024-09-13", "has_results": false, "last_update_posted_date": "2024-09-26", "last_synced_at": "2026-09-03T06:19:19.921Z", "location_count": 81, "location_summary": "Brandon, Florida • Cape Coral, Florida • Clearwater, Florida + 41 more", "locations": [ { "city": "Brandon", "state": "Florida" }, { "city": "Cape Coral", "state": "Florida" }, { "city": "Clearwater", "state": "Florida" }, { "city": "Coral Gables", "state": "Florida" }, { "city": "Davie", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT05569005" }, { "nct_id": "NCT01967719", "title": "Nicotine Pharmacokinetic Profile and Safety of the Tobacco Heating System 2.2 Menthol (THS 2.2 Menthol)", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Smoking" ], "interventions": [ { "name": "mTHS 2.2", "type": "OTHER" }, { "name": "mCC", "type": "OTHER" }, { "name": "NNS", "type": "OTHER" } ], "intervention_types": [ "OTHER" ], "sponsor": "Philip Morris Products S.A.", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "22 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "22 Years to 65 Years" }, "enrollment_count": 64, "start_date": "2013-10", "completion_date": "2014-05", "has_results": true, "last_update_posted_date": "2020-03-18", "last_synced_at": "2026-09-03T06:19:19.921Z", "location_count": 1, "location_summary": "Lexington, Kentucky", "locations": [ { "city": "Lexington", "state": "Kentucky" } ], "official_url": "https://clinicaltrials.gov/study/NCT01967719" }, { "nct_id": "NCT02396381", "title": "Evaluation of Biological and Functional Changes in Healthy Smokers After Switching to THS 2.2 for 26 Weeks", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "NA" ], "conditions": [ "Smoking" ], "interventions": [ { "name": "THS 2.2", "type": "OTHER" }, { "name": "CC", "type": "OTHER" } ], "intervention_types": [ "OTHER" ], "sponsor": "Philip Morris Products S.A.", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "30 Years", "maximum_age": null, "sex": "ALL", "summary": "30 Years and older" }, "enrollment_count": 1039, "start_date": "2015-03-12", "completion_date": "2017-08-01", "has_results": true, "last_update_posted_date": "2023-01-26", "last_synced_at": "2026-09-03T06:19:19.921Z", "location_count": 19, "location_summary": "Tempe, Arizona • Clearwater, Florida • Daytona Beach, Florida + 16 more", "locations": [ { "city": "Tempe", "state": "Arizona" }, { "city": "Clearwater", "state": "Florida" }, { "city": "Daytona Beach", "state": "Florida" }, { "city": "Orlando", "state": "Florida" }, { "city": "Tampa", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT02396381" } ] }