{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=TMR",
    "query": {
      "intervention": "TMR"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 24,
    "total_pages": 3,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=TMR&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-05T23:37:18.417Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT05009394",
      "title": "Surgical Treatments for Postamputation Pain",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Residual Limb Pain",
        "Amputation Neuroma",
        "Phantom Limb Pain",
        "Pain, Neuropathic",
        "Pain, Nerve"
      ],
      "interventions": [
        {
          "name": "Targeted Muscle Reinnervation (TMR)",
          "type": "PROCEDURE"
        },
        {
          "name": "Regenerative Peripheral Nerve Interface (RPNI)",
          "type": "PROCEDURE"
        },
        {
          "name": "Standard neuroma treatment, neuroma excision, and muscle burying",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Prometei Pain Rehabilitation Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 110,
      "start_date": "2023-06-20",
      "completion_date": "2029-06",
      "has_results": false,
      "last_update_posted_date": "2025-01-09",
      "last_synced_at": "2026-09-05T23:37:18.417Z",
      "location_count": 3,
      "location_summary": "Chicago, Illinois • Boston, Massachusetts • Ann Arbor, Michigan",
      "locations": [
        {
          "city": "Chicago",
          "state": "Illinois"
        },
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "Ann Arbor",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05009394"
    },
    {
      "nct_id": "NCT03043742",
      "title": "Stem Cell Heart Injections During Laser Revascularization Surgery for Treatment of Chronic Ischemic Heart Disease",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Chronic Ischemic Heart Disease"
      ],
      "interventions": [
        {
          "name": "Bone Marrow Derived Autologous CD133+ Selected Cell Product",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Michael Sekela",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 8,
      "start_date": "2016-07-12",
      "completion_date": "2020-11-12",
      "has_results": false,
      "last_update_posted_date": "2020-12-11",
      "last_synced_at": "2026-09-05T23:37:18.417Z",
      "location_count": 1,
      "location_summary": "Lexington, Kentucky",
      "locations": [
        {
          "city": "Lexington",
          "state": "Kentucky"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03043742"
    },
    {
      "nct_id": "NCT02205385",
      "title": "Targeted Reinnervation as a Means to Treat Neuromas Associated With Major Limb Amputation",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Neuroma",
        "Neuroma Amputation",
        "Pain"
      ],
      "interventions": [
        {
          "name": "Targeted Muscle Reinnervation",
          "type": "PROCEDURE"
        },
        {
          "name": "Traction Neurectomy",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Northwestern University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 27,
      "start_date": "2014-10",
      "completion_date": "2018-01-01",
      "has_results": false,
      "last_update_posted_date": "2018-01-03",
      "last_synced_at": "2026-09-05T23:37:18.417Z",
      "location_count": 6,
      "location_summary": "Chicago, Illinois • Bethesda, Maryland • Columbus, Ohio + 3 more",
      "locations": [
        {
          "city": "Chicago",
          "state": "Illinois"
        },
        {
          "city": "Bethesda",
          "state": "Maryland"
        },
        {
          "city": "Columbus",
          "state": "Ohio"
        },
        {
          "city": "Oklahoma City",
          "state": "Oklahoma"
        },
        {
          "city": "Nashville",
          "state": "Tennessee"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02205385"
    },
    {
      "nct_id": "NCT02349035",
      "title": "Application of Targeted Reinnervation for People With Transradial Amputation",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Amputation; Traumatic, Hand, and Wrist",
        "Amputation; Traumatic, Hand, at Wrist Level"
      ],
      "interventions": [
        {
          "name": "Compare control of multifunction transradial prosthesis",
          "type": "DEVICE"
        },
        {
          "name": "Perform TMR surgery and evaluate transradial TMR pattern recognition control of multifunctional prostheses.",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "PROCEDURE"
      ],
      "sponsor": "Shirley Ryan AbilityLab",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "95 Years",
        "sex": "ALL",
        "summary": "18 Years to 95 Years"
      },
      "enrollment_count": 10,
      "start_date": "2014-12",
      "completion_date": "2022-01",
      "has_results": false,
      "last_update_posted_date": "2021-05-13",
      "last_synced_at": "2026-09-05T23:37:18.417Z",
      "location_count": 3,
      "location_summary": "Chicago, Illinois • Bethesda, Maryland • Fort Sam Houston, Texas",
      "locations": [
        {
          "city": "Chicago",
          "state": "Illinois"
        },
        {
          "city": "Bethesda",
          "state": "Maryland"
        },
        {
          "city": "Fort Sam Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02349035"
    },
    {
      "nct_id": "NCT06160882",
      "title": "Powered Prosthesis for Use With TF Osseointegration Recipients",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Amputation"
      ],
      "interventions": [
        {
          "name": "Powered Prosthesis Training and EMG data collection",
          "type": "OTHER"
        },
        {
          "name": "Perform Osseointegration (OI) surgery and Targeted Muscle Reinnervation (TMR)",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "OTHER",
        "PROCEDURE"
      ],
      "sponsor": "Shirley Ryan AbilityLab",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "18 Years to 70 Years"
      },
      "enrollment_count": 6,
      "start_date": "2024-01-01",
      "completion_date": "2028-10",
      "has_results": false,
      "last_update_posted_date": "2025-03-18",
      "last_synced_at": "2026-09-05T23:37:18.417Z",
      "location_count": 1,
      "location_summary": "Chicago, Illinois",
      "locations": [
        {
          "city": "Chicago",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06160882"
    },
    {
      "nct_id": "NCT02189031",
      "title": "Sensory Feedback for Touch and Proprioception With Prosthetic Limbs",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Prosthetic"
      ],
      "interventions": [
        {
          "name": "Tactor array",
          "type": "DEVICE"
        },
        {
          "name": "Bypass Tactor",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Louis Stokes VA Medical Center",
      "sponsor_class": "FED",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 21,
      "start_date": "2013-02",
      "completion_date": "2023-11-17",
      "has_results": false,
      "last_update_posted_date": "2026-09-01",
      "last_synced_at": "2026-09-05T23:37:18.417Z",
      "location_count": 3,
      "location_summary": "Chicago, Ill • Cleveland, Ohio",
      "locations": [
        {
          "city": "Chicago",
          "state": "Ill"
        },
        {
          "city": "Cleveland",
          "state": "Ohio"
        },
        {
          "city": "Cleveland",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02189031"
    },
    {
      "nct_id": "NCT04658368",
      "title": "Patient Reported Outcomes Following Targeted Muscle Reinnervation",
      "overall_status": "TERMINATED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Amputation"
      ],
      "interventions": [
        {
          "name": "Primary TMR",
          "type": "PROCEDURE"
        },
        {
          "name": "Secondary TMR",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "University of Wisconsin, Madison",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 2,
      "start_date": "2020-12-29",
      "completion_date": "2022-09-01",
      "has_results": false,
      "last_update_posted_date": "2025-11-05",
      "last_synced_at": "2026-09-05T23:37:18.417Z",
      "location_count": 1,
      "location_summary": "Madison, Wisconsin",
      "locations": [
        {
          "city": "Madison",
          "state": "Wisconsin"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04658368"
    },
    {
      "nct_id": "NCT05408520",
      "title": "Targeted Muscle Reinnervation Study (TMR)",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Amputation"
      ],
      "interventions": [
        {
          "name": "Targeted Muscle Reinnervation",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "University of Arizona",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "99 Years",
        "sex": "ALL",
        "summary": "18 Years to 99 Years"
      },
      "enrollment_count": 0,
      "start_date": "2022-04-27",
      "completion_date": "2023-10-25",
      "has_results": false,
      "last_update_posted_date": "2026-07-24",
      "last_synced_at": "2026-09-05T23:37:18.417Z",
      "location_count": 1,
      "location_summary": "Phoenix, Arizona",
      "locations": [
        {
          "city": "Phoenix",
          "state": "Arizona"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05408520"
    },
    {
      "nct_id": "NCT06926036",
      "title": "Micromanaging Human Sleep Physiology to Treat Sleep Apnea and Other Disorders",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Sleep Apnea Obstructive (OSA)"
      ],
      "interventions": [
        {
          "name": "Wake training + TMR",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Northwestern University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "60 Years",
        "sex": "ALL",
        "summary": "18 Years to 60 Years"
      },
      "enrollment_count": 18,
      "start_date": "2025-04-03",
      "completion_date": "2027-04",
      "has_results": false,
      "last_update_posted_date": "2026-07-15",
      "last_synced_at": "2026-09-05T23:37:18.417Z",
      "location_count": 1,
      "location_summary": "Chicago, Illinois",
      "locations": [
        {
          "city": "Chicago",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06926036"
    },
    {
      "nct_id": "NCT03097978",
      "title": "Comparison of Pattern Recognition Control and Direct Control in TMR",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Amputation",
        "Amputation; Traumatic, Arm, Upper"
      ],
      "interventions": [
        {
          "name": "Commercial system",
          "type": "DEVICE"
        },
        {
          "name": "RIC arm system",
          "type": "DEVICE"
        },
        {
          "name": "Direct Control",
          "type": "OTHER"
        },
        {
          "name": "Pattern Recognition",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "OTHER"
      ],
      "sponsor": "Shirley Ryan AbilityLab",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "95 Years",
        "sex": "ALL",
        "summary": "18 Years to 95 Years"
      },
      "enrollment_count": 11,
      "start_date": "2013-06",
      "completion_date": "2017-09-29",
      "has_results": false,
      "last_update_posted_date": "2018-02-23",
      "last_synced_at": "2026-09-05T23:37:18.417Z",
      "location_count": 1,
      "location_summary": "Chicago, Illinois",
      "locations": [
        {
          "city": "Chicago",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03097978"
    }
  ]
}