{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=TNF+inhibitors", "query": { "intervention": "TNF inhibitors" }, "page_size": 10 }, "pagination": { "page": 1, "page_size": 10, "total_count": 76, "total_pages": 8, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=TNF+inhibitors&page=2&page_size=10", "previous_page_url": null }, "source": "remote", "last_synced_at": "2026-09-16T14:45:19.077Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT02696798", "title": "A Study of Ixekizumab (LY2439821) in TNF Inhibitor Experienced Participants With Radiographic Axial Spondyloarthritis", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Spondyloarthritis" ], "interventions": [ { "name": "Ixekizumab", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Eli Lilly and Company", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 316, "start_date": "2016-04-12", "completion_date": "2019-05-03", "has_results": true, "last_update_posted_date": "2020-06-17", "last_synced_at": "2026-09-16T14:45:19.077Z", "location_count": 27, "location_summary": "Phoenix, Arizona • Escondido, California • Huntington Beach, California + 24 more", "locations": [ { "city": "Phoenix", "state": "Arizona" }, { "city": "Escondido", "state": "California" }, { "city": "Huntington Beach", "state": "California" }, { "city": "Palm Desert", "state": "California" }, { "city": "Colorado Springs", "state": "Colorado" } ], "official_url": "https://clinicaltrials.gov/study/NCT02696798" }, { "nct_id": "NCT01202773", "title": "A Study in Participants With Rheumatoid Arthritis", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Rheumatoid Arthritis" ], "interventions": [ { "name": "LY2127399", "type": "DRUG" }, { "name": "Placebo Q4W", "type": "DRUG" }, { "name": "Placebo Q2W", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Eli Lilly and Company", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 456, "start_date": "2011-01", "completion_date": "2014-01", "has_results": true, "last_update_posted_date": "2018-05-14", "last_synced_at": "2026-09-16T14:45:19.077Z", "location_count": 110, "location_summary": "Birmingham, Alabama • Huntsville, Alabama • Paradise Valley, Arizona + 107 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "Huntsville", "state": "Alabama" }, { "city": "Paradise Valley", "state": "Arizona" }, { "city": "Phoenix", "state": "Arizona" }, { "city": "Scottsdale", "state": "Arizona" } ], "official_url": "https://clinicaltrials.gov/study/NCT01202773" }, { "nct_id": "NCT03652961", "title": "Rheumatoid Arthritis Memory B Cells and Abatacept", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Rheumatoid Arthritis" ], "interventions": [ { "name": "Abatacept", "type": "DRUG" }, { "name": "DMARDs", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "NYU Langone Health", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 25, "start_date": "2019-06-02", "completion_date": "2021-09-27", "has_results": true, "last_update_posted_date": "2024-07-03", "last_synced_at": "2026-09-16T14:45:19.077Z", "location_count": 1, "location_summary": "Lebanon, New Hampshire", "locations": [ { "city": "Lebanon", "state": "New Hampshire" } ], "official_url": "https://clinicaltrials.gov/study/NCT03652961" }, { "nct_id": "NCT04725422", "title": "CHronic Nonbacterial Osteomyelitis International Registry", "overall_status": "RECRUITING", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Chronic Nonbacterial Osteomyelitis", "Chronic Recurrent Multifocal Osteomyelitis" ], "interventions": [ { "name": "Methotrexate", "type": "DRUG" }, { "name": "Sulfasalazine", "type": "DRUG" }, { "name": "Leflunomide", "type": "DRUG" }, { "name": "Pamidronate", "type": "DRUG" }, { "name": "Zoledronic acid", "type": "DRUG" }, { "name": "Etanercept", "type": "DRUG" }, { "name": "Adalimumab", "type": "DRUG" }, { "name": "Certolizumab", "type": "DRUG" }, { "name": "Infliximab", "type": "DRUG" }, { "name": "Golimumab", "type": "DRUG" }, { "name": "NSAID", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Seattle Children's Hospital", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": null, "maximum_age": "21 Years", "sex": "ALL", "summary": "Up to 21 Years" }, "enrollment_count": 2000, "start_date": "2018-08-01", "completion_date": "2050-08", "has_results": false, "last_update_posted_date": "2024-07-30", "last_synced_at": "2026-09-16T14:45:19.077Z", "location_count": 1, "location_summary": "Seattle, Washington", "locations": [ { "city": "Seattle", "state": "Washington" } ], "official_url": "https://clinicaltrials.gov/study/NCT04725422" }, { "nct_id": "NCT04370236", "title": "INB03 for the Treatment of Pulmonary Complications From COVID-19", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2", "PHASE3" ], "conditions": [ "COVID-19" ], "interventions": [ { "name": "INB03", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Inmune Bio, Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 79, "start_date": "2020-10-21", "completion_date": "2021-11-18", "has_results": true, "last_update_posted_date": "2026-05-19", "last_synced_at": "2026-09-16T14:45:19.077Z", "location_count": 9, "location_summary": "Jonesboro, Arkansas • Louisville, Kentucky • Kosciusko, Mississippi + 4 more", "locations": [ { "city": "Jonesboro", "state": "Arkansas" }, { "city": "Jonesboro", "state": "Arkansas" }, { "city": "Louisville", "state": "Kentucky" }, { "city": "Kosciusko", "state": "Mississippi" }, { "city": "Southard", "state": "Missouri" } ], "official_url": "https://clinicaltrials.gov/study/NCT04370236" }, { "nct_id": "NCT00311246", "title": "Trial of Adalimumab in Progressive Sarcoidosis", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Sarcoidosis" ], "interventions": [ { "name": "Adalimumab", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "University of Chicago", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "85 Years", "sex": "ALL", "summary": "18 Years to 85 Years" }, "enrollment_count": 11, "start_date": "2006-04", "completion_date": "2008-09", "has_results": true, "last_update_posted_date": "2020-08-25", "last_synced_at": "2026-09-16T14:45:19.077Z", "location_count": 1, "location_summary": "Chicago, Illinois", "locations": [ { "city": "Chicago", "state": "Illinois" } ], "official_url": "https://clinicaltrials.gov/study/NCT00311246" }, { "nct_id": "NCT04086745", "title": "A Study of Baricitinib in Participants With Rheumatoid Arthritis", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Rheumatoid Arthritis" ], "interventions": [ { "name": "Baricitinib", "type": "DRUG" }, { "name": "TNF Inhibitor", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Eli Lilly and Company", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 1050, "start_date": "2020-02-14", "completion_date": "2025-05-19", "has_results": true, "last_update_posted_date": "2026-07-10", "last_synced_at": "2026-09-16T14:45:19.077Z", "location_count": 119, "location_summary": "Chandler, Arizona • Mesa, Arizona • Paradise Valley, Arizona + 104 more", "locations": [ { "city": "Chandler", "state": "Arizona" }, { "city": "Mesa", "state": "Arizona" }, { "city": "Paradise Valley", "state": "Arizona" }, { "city": "Peoria", "state": "Arizona" }, { "city": "Phoenix", "state": "Arizona" } ], "official_url": "https://clinicaltrials.gov/study/NCT04086745" }, { "nct_id": "NCT03001219", "title": "A Study of RO7123520 to Evaluate the Safety and Efficacy in Participants With Moderately To Severely Active Rheumatoid Arthritis (RA) Who Are Inadequately Responding to Anti-Tumor Necrosis Factor (TNF)-Alpha Therapy", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Rheumatoid Arthritis" ], "interventions": [ { "name": "Anti-TNF-alpha", "type": "DRUG" }, { "name": "Methotrexate", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" }, { "name": "RO7123520", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Hoffmann-La Roche", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 109, "start_date": "2016-12-22", "completion_date": "2018-11-06", "has_results": true, "last_update_posted_date": "2020-01-29", "last_synced_at": "2026-09-16T14:45:19.077Z", "location_count": 32, "location_summary": "Anniston, Alabama • Glendale, Arizona • Mesa, Arizona + 25 more", "locations": [ { "city": "Anniston", "state": "Alabama" }, { "city": "Glendale", "state": "Arizona" }, { "city": "Mesa", "state": "Arizona" }, { "city": "Phoenix", "state": "Arizona" }, { "city": "Covina", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT03001219" }, { "nct_id": "NCT00408629", "title": "Efficacy and Safety of Adalimumab in Subjects With Moderately to Severely Active Ulcerative Colitis", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Ulcerative Colitis" ], "interventions": [ { "name": "adalimumab", "type": "BIOLOGICAL" }, { "name": "placebo", "type": "BIOLOGICAL" } ], "intervention_types": [ "BIOLOGICAL" ], "sponsor": "Abbott", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 518, "start_date": "2006-11", "completion_date": "2010-03", "has_results": true, "last_update_posted_date": "2011-05-03", "last_synced_at": "2026-09-16T14:45:19.077Z", "location_count": 36, "location_summary": "Anaheim, California • Wheat Ridge, Colorado • Hamden, Connecticut + 29 more", "locations": [ { "city": "Anaheim", "state": "California" }, { "city": "Wheat Ridge", "state": "Colorado" }, { "city": "Hamden", "state": "Connecticut" }, { "city": "Gainesville", "state": "Florida" }, { "city": "Hollywood", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT00408629" }, { "nct_id": "NCT01981473", "title": "Drug Concentration, Immunogenicity, and Efficacy Study in Patients With Rheumatoid Arthritis Currently Treated With Etanercept, Adalimumab, or Infliximab", "overall_status": "COMPLETED", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Rheumatoid Arthritis" ], "interventions": [ { "name": "no intervention", "type": "OTHER" } ], "intervention_types": [ "OTHER" ], "sponsor": "Pfizer", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 605, "start_date": "2014-01", "completion_date": "2014-12", "has_results": true, "last_update_posted_date": "2016-01-12", "last_synced_at": "2026-09-16T14:45:19.077Z", "location_count": 34, "location_summary": "Glendale, Arizona • Mesa, Arizona • Phoenix, Arizona + 29 more", "locations": [ { "city": "Glendale", "state": "Arizona" }, { "city": "Mesa", "state": "Arizona" }, { "city": "Phoenix", "state": "Arizona" }, { "city": "Phoenix", "state": "Arizona" }, { "city": "Sun City", "state": "Arizona" } ], "official_url": "https://clinicaltrials.gov/study/NCT01981473" } ] }