{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Targeted+agent&page=52",
    "query": {
      "intervention": "Targeted agent",
      "page": 52
    },
    "page_size": 10
  },
  "pagination": {
    "page": 52,
    "page_size": 10,
    "total_count": 1323,
    "total_pages": 133,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Targeted+agent&page=53&page_size=10",
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Targeted+agent&page=51&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-11-06T10:23:59.311Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT05116683",
      "title": "ATX-101 in Advanced Dedifferentiated Liposarcoma and Leiomyosarcoma",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Leiomyosarcoma",
        "Liposarcoma"
      ],
      "interventions": [
        {
          "name": "ATX-101",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Benjamin Izar",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "99 Years",
        "sex": "ALL",
        "summary": "18 Years to 99 Years"
      },
      "enrollment_count": 4,
      "start_date": "2022-01-11",
      "completion_date": "2022-10-27",
      "has_results": true,
      "last_update_posted_date": "2023-12-06",
      "last_synced_at": "2026-11-06T10:23:59.311Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05116683"
    },
    {
      "nct_id": "NCT04592380",
      "title": "Clevidipine vs Placebo or Standard of Care for Dyspnea and Blood Pressure Control in AHF",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Dyspnea",
        "Hypertension",
        "Acute Heart Failure"
      ],
      "interventions": [
        {
          "name": "Stage 1: Clevidipine (double-blinded)",
          "type": "DRUG"
        },
        {
          "name": "Stage 1: Placebo (double-blinded)",
          "type": "DRUG"
        },
        {
          "name": "Stage 2: Clevidipine (open-label)",
          "type": "DRUG"
        },
        {
          "name": "Stage 2: Standard of Care (open-label)",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "The Medicines Company",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 0,
      "start_date": "2014-08",
      "completion_date": "2016-11",
      "has_results": false,
      "last_update_posted_date": "2020-10-19",
      "last_synced_at": "2026-11-06T10:23:59.311Z",
      "location_count": 9,
      "location_summary": "Montgomery, Alabama • Tucson, Arizona • St Louis, Missouri + 5 more",
      "locations": [
        {
          "city": "Montgomery",
          "state": "Alabama"
        },
        {
          "city": "Tucson",
          "state": "Arizona"
        },
        {
          "city": "St Louis",
          "state": "Missouri"
        },
        {
          "city": "Brooklyn",
          "state": "New York"
        },
        {
          "city": "Brooklyn",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04592380"
    },
    {
      "nct_id": "NCT03629990",
      "title": "Approach Bias Modification for the Treatment of Cannabis Use Disorder",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Cannabis Use Disorder"
      ],
      "interventions": [
        {
          "name": "Approach Bias Modification (ABM)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Sham ABM",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Psychosocial therapy for cannabis use disorder.",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Medical University of South Carolina",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 104,
      "start_date": "2019-01-16",
      "completion_date": "2023-10-30",
      "has_results": true,
      "last_update_posted_date": "2024-12-17",
      "last_synced_at": "2026-11-06T10:23:59.311Z",
      "location_count": 1,
      "location_summary": "Charleston, South Carolina",
      "locations": [
        {
          "city": "Charleston",
          "state": "South Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03629990"
    },
    {
      "nct_id": "NCT07026981",
      "title": "[Ga-68]MTP220 PET for Biodistribution and Efficacy in Pancreatic Cancer and Head and Neck Cancers",
      "overall_status": "NOT_YET_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "EARLY_PHASE1"
      ],
      "conditions": [
        "Head and Neck Cancer",
        "Pancreatic Cancer",
        "Cancer Pancreas"
      ],
      "interventions": [
        {
          "name": "[Ga-68]MTP220 PET/CT Scan",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Qiubai Li",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 12,
      "start_date": "2025-09",
      "completion_date": "2026-12-31",
      "has_results": false,
      "last_update_posted_date": "2025-08-08",
      "last_synced_at": "2026-11-06T10:23:59.311Z",
      "location_count": 1,
      "location_summary": "Cleveland, Ohio",
      "locations": [
        {
          "city": "Cleveland",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07026981"
    },
    {
      "nct_id": "NCT05020678",
      "title": "NKX019, Intravenous Allogeneic Chimeric Antigen Receptor Natural Killer Cells (CAR NK), in Adults With B-cell Cancers",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Lymphoma, Non-Hodgkin",
        "B-cell Acute Lymphoblastic Leukemia",
        "Large B-cell Lymphoma",
        "Mantle Cell Lymphoma",
        "Indolent Lymphoma",
        "Waldenstrom Macroglobulinemia",
        "Chronic Lymphocytic Leukemia",
        "Small Lymphocytic Lymphoma",
        "Aggressive Lymphoma",
        "Large-cell Lymphoma"
      ],
      "interventions": [
        {
          "name": "NKX019",
          "type": "BIOLOGICAL"
        }
      ],
      "intervention_types": [
        "BIOLOGICAL"
      ],
      "sponsor": "Nkarta, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 150,
      "start_date": "2021-08-20",
      "completion_date": "2038-12",
      "has_results": false,
      "last_update_posted_date": "2026-04-20",
      "last_synced_at": "2026-11-06T10:23:59.311Z",
      "location_count": 2,
      "location_summary": "Denver, Colorado • Cleveland, Ohio",
      "locations": [
        {
          "city": "Denver",
          "state": "Colorado"
        },
        {
          "city": "Cleveland",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05020678"
    },
    {
      "nct_id": "NCT07176208",
      "title": "Clinical Study to Evaluate the Effects of Oral Delta-9-tetrahydrocannabinol (Δ9-THC) With and Without Alcohol on Perception and Driving Performance in Healthy Adults",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Cannabis, Drug Effects",
        "Driving Performance"
      ],
      "interventions": [
        {
          "name": "5 mg Dronabinol (Marinol®) + Placebo Beverage",
          "type": "DRUG"
        },
        {
          "name": "10 mg Dronabinol (Marinol®) + Placebo Beverage",
          "type": "DRUG"
        },
        {
          "name": "5 mg Dronabinol (Marinol®) + Alcohol Beverage",
          "type": "DRUG"
        },
        {
          "name": "10 mg Dronabinol (Marinol®) + Alcohol Beverage",
          "type": "DRUG"
        },
        {
          "name": "Placebo Capsule + Alcohol Beverage",
          "type": "DRUG"
        },
        {
          "name": "Placebo Capsule + Placebo Beverage",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Food and Drug Administration (FDA)",
      "sponsor_class": "FED",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "55 Years",
        "sex": "ALL",
        "summary": "21 Years to 55 Years"
      },
      "enrollment_count": 48,
      "start_date": "2025-12-29",
      "completion_date": "2026-06-19",
      "has_results": false,
      "last_update_posted_date": "2026-09-30",
      "last_synced_at": "2026-11-06T10:23:59.311Z",
      "location_count": 2,
      "location_summary": "West Bend, Wisconsin",
      "locations": [
        {
          "city": "West Bend",
          "state": "Wisconsin"
        },
        {
          "city": "West Bend",
          "state": "Wisconsin"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07176208"
    },
    {
      "nct_id": "NCT04801589",
      "title": "Goal-Directed Sedation in Mechanically Ventilated Infants and Children",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Delirium",
        "Critical Illness",
        "Sedation Complication",
        "Executive Dysfunction",
        "Post Traumatic Stress Disorder"
      ],
      "interventions": [
        {
          "name": "Dexmedetomidine",
          "type": "DRUG"
        },
        {
          "name": "Midazolam",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Vanderbilt University Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "44 Weeks",
        "maximum_age": "11 Years",
        "sex": "ALL",
        "summary": "44 Weeks to 11 Years"
      },
      "enrollment_count": 372,
      "start_date": "2021-05-10",
      "completion_date": "2026-10-30",
      "has_results": false,
      "last_update_posted_date": "2026-10-20",
      "last_synced_at": "2026-11-06T10:23:59.311Z",
      "location_count": 1,
      "location_summary": "Nashville, Tennessee",
      "locations": [
        {
          "city": "Nashville",
          "state": "Tennessee"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04801589"
    },
    {
      "nct_id": "NCT03605927",
      "title": "CD40-L Blockade for Prevention of Acute Graft-Versus-Host Disease",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Graft-versus-host-disease",
        "GVHD",
        "GVHD, Acute"
      ],
      "interventions": [
        {
          "name": "BMS-986004",
          "type": "DRUG"
        },
        {
          "name": "Sirolimus",
          "type": "DRUG"
        },
        {
          "name": "Tacrolimus",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "H. Lee Moffitt Cancer Center and Research Institute",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 45,
      "start_date": "2019-02-15",
      "completion_date": "2023-07-25",
      "has_results": false,
      "last_update_posted_date": "2026-04-02",
      "last_synced_at": "2026-11-06T10:23:59.311Z",
      "location_count": 3,
      "location_summary": "Duarte, California • Tampa, Florida • Columbus, Ohio",
      "locations": [
        {
          "city": "Duarte",
          "state": "California"
        },
        {
          "city": "Tampa",
          "state": "Florida"
        },
        {
          "city": "Columbus",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03605927"
    },
    {
      "nct_id": "NCT07847918",
      "title": "A Fully Remote Feasibility Trial of Phenylbutyrate for SLC6A1-Related Disorders",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "SLC6A1"
      ],
      "interventions": [
        {
          "name": "Glycerol Phenylbutyrate",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Scripps Translational Science Institute",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "2 Years",
        "maximum_age": "60 Years",
        "sex": "ALL",
        "summary": "2 Years to 60 Years"
      },
      "enrollment_count": 20,
      "start_date": "2026-10",
      "completion_date": "2032-10",
      "has_results": false,
      "last_update_posted_date": "2026-09-29",
      "last_synced_at": "2026-11-06T10:23:59.311Z",
      "location_count": 1,
      "location_summary": "San Diego, California",
      "locations": [
        {
          "city": "San Diego",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07847918"
    },
    {
      "nct_id": "NCT06095050",
      "title": "Embolization Treatment of Chronic Refractory Shoulder Tendinopathy",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Shoulder Pain",
        "Tendinopathy",
        "Rotator Cuff Tendinitis",
        "Rotator Cuff Tendinosis",
        "Embolization",
        "Arterial Occlusion"
      ],
      "interventions": [
        {
          "name": "Embolization",
          "type": "DEVICE"
        },
        {
          "name": "Physical Therapy",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "OTHER"
      ],
      "sponsor": "Brigham and Women's Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "80 Years",
        "sex": "ALL",
        "summary": "21 Years to 80 Years"
      },
      "enrollment_count": 41,
      "start_date": "2025-01-16",
      "completion_date": "2028-04-21",
      "has_results": false,
      "last_update_posted_date": "2026-02-06",
      "last_synced_at": "2026-11-06T10:23:59.311Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06095050"
    }
  ]
}