{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Thermal+Environment",
    "query": {
      "intervention": "Thermal Environment"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 29,
    "total_pages": 3,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Thermal+Environment&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-11T13:41:07.457Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT04284397",
      "title": "Identification of Critical Thermal Environments for Aged Adults",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "EARLY_PHASE1"
      ],
      "conditions": [
        "Aging"
      ],
      "interventions": [
        {
          "name": "Low dose ASA",
          "type": "DRUG"
        },
        {
          "name": "Control",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER"
      ],
      "sponsor": "Penn State University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 190,
      "start_date": "2020-12-30",
      "completion_date": "2027-02-27",
      "has_results": false,
      "last_update_posted_date": "2026-01-27",
      "last_synced_at": "2026-09-11T13:41:07.457Z",
      "location_count": 1,
      "location_summary": "University Park, Pennsylvania",
      "locations": [
        {
          "city": "University Park",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04284397"
    },
    {
      "nct_id": "NCT01228929",
      "title": "Non-invasive Ocular Surface Measurements Before and After Interventions",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Dry Eye Syndrome",
        "Healthy"
      ],
      "interventions": [
        {
          "name": "Environmental Chamber Condition Change Intervention",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Rochester",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "89 Years",
        "sex": "ALL",
        "summary": "18 Years to 89 Years"
      },
      "enrollment_count": 18,
      "start_date": "2010-07",
      "completion_date": "2014-01",
      "has_results": true,
      "last_update_posted_date": "2015-10-12",
      "last_synced_at": "2026-09-11T13:41:07.457Z",
      "location_count": 1,
      "location_summary": "Rochester, New York",
      "locations": [
        {
          "city": "Rochester",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01228929"
    },
    {
      "nct_id": "NCT03643835",
      "title": "Efficacy of an Investigational Thermal Rehab Machine on Body Cooling in Hyperthermic Individuals",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Cryotherapy Effect"
      ],
      "interventions": [
        {
          "name": "Thermal Rehab Machine",
          "type": "DEVICE"
        },
        {
          "name": "Forearm Ice Towels",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "OTHER"
      ],
      "sponsor": "University of North Carolina, Greensboro",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "35 Years",
        "sex": "MALE",
        "summary": "18 Years to 35 Years · Male only"
      },
      "enrollment_count": 14,
      "start_date": "2018-09-17",
      "completion_date": "2018-12-31",
      "has_results": false,
      "last_update_posted_date": "2019-04-18",
      "last_synced_at": "2026-09-11T13:41:07.457Z",
      "location_count": 1,
      "location_summary": "Greensboro, North Carolina",
      "locations": [
        {
          "city": "Greensboro",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03643835"
    },
    {
      "nct_id": "NCT06985940",
      "title": "Visual and Acoustic Effects of Human Thermal Comfort and Perception in a Micro-Climatically Steady Environment",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Thermal Perception"
      ],
      "interventions": [
        {
          "name": "Visual stimulation",
          "type": "OTHER"
        },
        {
          "name": "Acoustic stimulation",
          "type": "OTHER"
        },
        {
          "name": "Combination",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Wisconsin, Madison",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "40 Years",
        "sex": "ALL",
        "summary": "18 Years to 40 Years"
      },
      "enrollment_count": 0,
      "start_date": "2025-10",
      "completion_date": "2026-08",
      "has_results": false,
      "last_update_posted_date": "2025-10-20",
      "last_synced_at": "2026-09-11T13:41:07.457Z",
      "location_count": 1,
      "location_summary": "Madison, Wisconsin",
      "locations": [
        {
          "city": "Madison",
          "state": "Wisconsin"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06985940"
    },
    {
      "nct_id": "NCT02345629",
      "title": "Cordotomy for Refractory Cancer Pain",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Advanced Cancers",
        "Pain"
      ],
      "interventions": [
        {
          "name": "Cordotomy",
          "type": "PROCEDURE"
        },
        {
          "name": "Pain/Symptom Questionnaire",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Sharpness Sensory Testing",
          "type": "PROCEDURE"
        },
        {
          "name": "Heat Pain Sensory Testing",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE",
        "BEHAVIORAL"
      ],
      "sponsor": "M.D. Anderson Cancer Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 18,
      "start_date": "2015-03-10",
      "completion_date": "2020-02-25",
      "has_results": false,
      "last_update_posted_date": "2023-06-07",
      "last_synced_at": "2026-09-11T13:41:07.457Z",
      "location_count": 1,
      "location_summary": "Houston, Texas",
      "locations": [
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02345629"
    },
    {
      "nct_id": "NCT02748577",
      "title": "Pain Processing in Adults With Migraines",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Migraines"
      ],
      "interventions": [
        {
          "name": "Questionnaires",
          "type": "OTHER"
        },
        {
          "name": "Quantitative Sensory Testing (QST) Pain Measurements",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Wake Forest University Health Sciences",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 121,
      "start_date": "2016-08-24",
      "completion_date": "2019-07-16",
      "has_results": false,
      "last_update_posted_date": "2020-05-12",
      "last_synced_at": "2026-09-11T13:41:07.457Z",
      "location_count": 1,
      "location_summary": "Winston-Salem, North Carolina",
      "locations": [
        {
          "city": "Winston-Salem",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02748577"
    },
    {
      "nct_id": "NCT06405282",
      "title": "Weightlessness Associated Cephalad Fluid Shifts; The Potential to Evaluate Venous and Lymphatic Dysfunction",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Fluid Retention Tissue",
        "Perfusion; Complications"
      ],
      "interventions": [
        {
          "name": "Manual Lymphatic Drainage",
          "type": "OTHER"
        },
        {
          "name": "Near infrared spectroscopy",
          "type": "DEVICE"
        },
        {
          "name": "Temperature",
          "type": "DEVICE"
        },
        {
          "name": "Tissue Dialectic Constant",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "OTHER",
        "DEVICE"
      ],
      "sponsor": "Nova Southeastern University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "45 Years",
        "sex": "ALL",
        "summary": "18 Years to 45 Years"
      },
      "enrollment_count": 15,
      "start_date": "2022-04-14",
      "completion_date": "2022-06-25",
      "has_results": false,
      "last_update_posted_date": "2024-05-08",
      "last_synced_at": "2026-09-11T13:41:07.457Z",
      "location_count": 1,
      "location_summary": "Fort Lauderdale, Florida",
      "locations": [
        {
          "city": "Fort Lauderdale",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06405282"
    },
    {
      "nct_id": "NCT02062840",
      "title": "The Brain on Whole Body Hyperthermia: A Neuroimaging Study",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Major Depression"
      ],
      "interventions": [
        {
          "name": "High intensity whole-body infrared heating",
          "type": "DEVICE"
        },
        {
          "name": "Low intensity whole-body infrared heating",
          "type": "DEVICE"
        },
        {
          "name": "Functional Magnetic Resonance Imaging (fMRI) and electrocardiogram (EKG)",
          "type": "DEVICE"
        },
        {
          "name": "Questionnaires",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "OTHER"
      ],
      "sponsor": "University of Arizona",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "30 Years",
        "sex": "ALL",
        "summary": "18 Years to 30 Years"
      },
      "enrollment_count": 23,
      "start_date": "2014-02",
      "completion_date": "2015-05",
      "has_results": false,
      "last_update_posted_date": "2015-08-10",
      "last_synced_at": "2026-09-11T13:41:07.457Z",
      "location_count": 1,
      "location_summary": "Tucson, Arizona",
      "locations": [
        {
          "city": "Tucson",
          "state": "Arizona"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02062840"
    },
    {
      "nct_id": "NCT01375582",
      "title": "Objective Evaluation of Ocular Surface Lubricants in Two Environments",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "EARLY_PHASE1"
      ],
      "conditions": [
        "Dry Eye"
      ],
      "interventions": [
        {
          "name": "B & L Soothe Lubricant Eye Drops",
          "type": "DRUG"
        },
        {
          "name": "Liposic EDO",
          "type": "DRUG"
        },
        {
          "name": "OcuFresh Eye Wash",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Rochester",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "30 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "30 Years to 75 Years"
      },
      "enrollment_count": 20,
      "start_date": "2011-06",
      "completion_date": "2012-06",
      "has_results": false,
      "last_update_posted_date": "2022-11-22",
      "last_synced_at": "2026-09-11T13:41:07.457Z",
      "location_count": 1,
      "location_summary": "Rochester, New York",
      "locations": [
        {
          "city": "Rochester",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01375582"
    },
    {
      "nct_id": "NCT01822535",
      "title": "Body Temperature in Persons With Tetraplegia When Exposed to Cold",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Tetraplegia",
        "Hypothermia",
        "Mild Cognitive Impairment"
      ],
      "interventions": [
        {
          "name": "Midodrine hydrochloride",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "James J. Peters Veterans Affairs Medical Center",
      "sponsor_class": "FED",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "68 Years",
        "sex": "ALL",
        "summary": "18 Years to 68 Years"
      },
      "enrollment_count": 30,
      "start_date": "2011-07",
      "completion_date": "2015-10",
      "has_results": true,
      "last_update_posted_date": "2016-03-04",
      "last_synced_at": "2026-09-11T13:41:07.457Z",
      "location_count": 1,
      "location_summary": "The Bronx, New York",
      "locations": [
        {
          "city": "The Bronx",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01822535"
    }
  ]
}