{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Thermal+Stimuli",
    "query": {
      "intervention": "Thermal Stimuli"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 24,
    "total_pages": 3,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Thermal+Stimuli&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-04T16:23:54.440Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT02651467",
      "title": "A Study to Investigate Efficacy of Two Experimental Oral Rinses in Providing Long Term Relief From Pain Derived From Exposed Dentine in Response to Chemical, Thermal, Tactile, or Osmotic Stimuli.",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Dentin Sensitivity"
      ],
      "interventions": [
        {
          "name": "Experimental Oral Rinse 1 (1.5% w/w KOX, 0ppm F, pH 7.0)",
          "type": "OTHER"
        },
        {
          "name": "Experimental Oral Rinse 2 (2.0% w/w KOX, 45ppm F, pH 4.5)",
          "type": "OTHER"
        },
        {
          "name": "Placebo Oral Rinse (0% w/w KOX 0ppm F, pH 4.5 )",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "GlaxoSmithKline",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 221,
      "start_date": "2016-01-04",
      "completion_date": "2016-04-22",
      "has_results": true,
      "last_update_posted_date": "2018-08-27",
      "last_synced_at": "2026-09-04T16:23:54.440Z",
      "location_count": 1,
      "location_summary": "Fort Wayne, Indiana",
      "locations": [
        {
          "city": "Fort Wayne",
          "state": "Indiana"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02651467"
    },
    {
      "nct_id": "NCT06472622",
      "title": "Functional Neuroimaging to Detect the Neural Signatures of the Unpleasantness of Pain and Effort",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "EARLY_PHASE1"
      ],
      "conditions": [
        "Fatigue Syndrome, Chronic"
      ],
      "interventions": [
        {
          "name": "Thermal Pain Stimulation",
          "type": "DEVICE"
        },
        {
          "name": "Physical Effort Stimulation",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "National Institute of Neurological Disorders and Stroke (NINDS)",
      "sponsor_class": "NIH",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "50 Years",
        "sex": "ALL",
        "summary": "18 Years to 50 Years"
      },
      "enrollment_count": 47,
      "start_date": "2025-04-09",
      "completion_date": "2034-06-30",
      "has_results": false,
      "last_update_posted_date": "2026-08-20",
      "last_synced_at": "2026-09-04T16:23:54.440Z",
      "location_count": 1,
      "location_summary": "Bethesda, Maryland",
      "locations": [
        {
          "city": "Bethesda",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06472622"
    },
    {
      "nct_id": "NCT05145595",
      "title": "Pain Sensitivity During Puberty",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Pain"
      ],
      "interventions": [
        {
          "name": "Thermal Sensory Analyzer",
          "type": "DEVICE"
        },
        {
          "name": "Pressure Stimuli",
          "type": "DEVICE"
        },
        {
          "name": "Mechanical Stimuli",
          "type": "DEVICE"
        },
        {
          "name": "Pain Ratings",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Thermal pain thresholds",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Pressure pain thresholds (PPT)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Mechanical temporal summation",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Conditioned pain modulation (CPM) efficiency",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Offset analgesia efficiency",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Cold pain tolerance",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "BEHAVIORAL"
      ],
      "sponsor": "Washington University School of Medicine",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "9 Years",
        "maximum_age": "16 Years",
        "sex": "ALL",
        "summary": "9 Years to 16 Years"
      },
      "enrollment_count": 36,
      "start_date": "2022-09-20",
      "completion_date": "2024-07-17",
      "has_results": false,
      "last_update_posted_date": "2026-01-09",
      "last_synced_at": "2026-09-04T16:23:54.440Z",
      "location_count": 1,
      "location_summary": "St Louis, Missouri",
      "locations": [
        {
          "city": "St Louis",
          "state": "Missouri"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05145595"
    },
    {
      "nct_id": "NCT01030133",
      "title": "Effects of Transcranial Magnetic Stimulation (TMS) and Stimulus Controllability on Pain Perception",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Chronic Pain"
      ],
      "interventions": [
        {
          "name": "Operator Role Real TMS",
          "type": "DEVICE"
        },
        {
          "name": "Receiver Role Real TMS",
          "type": "DEVICE"
        },
        {
          "name": "Operator Role Sham TMS",
          "type": "DEVICE"
        },
        {
          "name": "Receiver Role Sham TMS",
          "type": "DEVICE"
        },
        {
          "name": "All Participants Operator Role",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Medical University of South Carolina",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "18 Years to 75 Years"
      },
      "enrollment_count": 28,
      "start_date": "2009-10",
      "completion_date": "2010-02",
      "has_results": true,
      "last_update_posted_date": "2018-09-28",
      "last_synced_at": "2026-09-04T16:23:54.440Z",
      "location_count": 1,
      "location_summary": "Charleston, South Carolina",
      "locations": [
        {
          "city": "Charleston",
          "state": "South Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01030133"
    },
    {
      "nct_id": "NCT06030297",
      "title": "Diode Laser as a Biomarker for Neuropathic Pain of Peripheral Origin.",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Peripheral Neuropathy"
      ],
      "interventions": [
        {
          "name": "Diode Laser fiber type Selective Stimulator",
          "type": "PROCEDURE"
        },
        {
          "name": "ZTlido 1.8 % Topical System",
          "type": "DRUG"
        },
        {
          "name": "PeriCam PSI NR",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Medoc Quantitative Sensory Testing",
          "type": "DIAGNOSTIC_TEST"
        },
        {
          "name": "Inactive Topical System",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "PROCEDURE",
        "DRUG",
        "DIAGNOSTIC_TEST",
        "OTHER"
      ],
      "sponsor": "University of Utah",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 75,
      "start_date": "2023-09-01",
      "completion_date": "2026-02-09",
      "has_results": false,
      "last_update_posted_date": "2026-04-17",
      "last_synced_at": "2026-09-04T16:23:54.440Z",
      "location_count": 2,
      "location_summary": "Palo Alto, California • Salt Lake City, Utah",
      "locations": [
        {
          "city": "Palo Alto",
          "state": "California"
        },
        {
          "city": "Salt Lake City",
          "state": "Utah"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06030297"
    },
    {
      "nct_id": "NCT03075254",
      "title": "Central Mechanisms of Chronic Pain and Fatigue Subtitle: Functional Imaging of Brain and Spinal Cord",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Chronic Fatigue Syndrome",
        "Fibromyalgia"
      ],
      "interventions": [
        {
          "name": "A Peltier for Sensory testing",
          "type": "DEVICE"
        },
        {
          "name": "functional magnetic resonance imaging for Brain Neuroimaging",
          "type": "DEVICE"
        },
        {
          "name": "fMRI for Spinal Cord Neuroimaging",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of Florida",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "18 Years to 70 Years"
      },
      "enrollment_count": 197,
      "start_date": "2017-03-15",
      "completion_date": "2024-10-29",
      "has_results": false,
      "last_update_posted_date": "2025-01-27",
      "last_synced_at": "2026-09-04T16:23:54.440Z",
      "location_count": 1,
      "location_summary": "Gainesville, Florida",
      "locations": [
        {
          "city": "Gainesville",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03075254"
    },
    {
      "nct_id": "NCT04664400",
      "title": "N-of-few Study of Pain Perception",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Healthy"
      ],
      "interventions": [
        {
          "name": "Symbolic conditioning",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Conditioning",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Instructions",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Counterfactual",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Trustees of Dartmouth College",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "55 Years",
        "sex": "ALL",
        "summary": "18 Years to 55 Years"
      },
      "enrollment_count": 10,
      "start_date": "2021-01-22",
      "completion_date": "2021-05-24",
      "has_results": true,
      "last_update_posted_date": "2023-04-18",
      "last_synced_at": "2026-09-04T16:23:54.440Z",
      "location_count": 1,
      "location_summary": "Hanover, New Hampshire",
      "locations": [
        {
          "city": "Hanover",
          "state": "New Hampshire"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04664400"
    },
    {
      "nct_id": "NCT06615245",
      "title": "Measuring Attention During Immersive Virtual Reality Distraction",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Distraction"
      ],
      "interventions": [
        {
          "name": "No VR vs. immersive high tech VR",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Plausible control vs immersive High Tech VR",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Hunter Hoffman",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 36,
      "start_date": "2024-10-01",
      "completion_date": "2024-11-24",
      "has_results": false,
      "last_update_posted_date": "2024-12-06",
      "last_synced_at": "2026-09-04T16:23:54.440Z",
      "location_count": 1,
      "location_summary": "Seattle, Washington",
      "locations": [
        {
          "city": "Seattle",
          "state": "Washington"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06615245"
    },
    {
      "nct_id": "NCT02345629",
      "title": "Cordotomy for Refractory Cancer Pain",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Advanced Cancers",
        "Pain"
      ],
      "interventions": [
        {
          "name": "Cordotomy",
          "type": "PROCEDURE"
        },
        {
          "name": "Pain/Symptom Questionnaire",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Sharpness Sensory Testing",
          "type": "PROCEDURE"
        },
        {
          "name": "Heat Pain Sensory Testing",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE",
        "BEHAVIORAL"
      ],
      "sponsor": "M.D. Anderson Cancer Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 18,
      "start_date": "2015-03-10",
      "completion_date": "2020-02-25",
      "has_results": false,
      "last_update_posted_date": "2023-06-07",
      "last_synced_at": "2026-09-04T16:23:54.440Z",
      "location_count": 1,
      "location_summary": "Houston, Texas",
      "locations": [
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02345629"
    },
    {
      "nct_id": "NCT06785129",
      "title": "Endometriosis and Migraine",
      "overall_status": "RECRUITING",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Migraine",
        "Endometriosis"
      ],
      "interventions": [
        {
          "name": "Thermal stimuli",
          "type": "DEVICE"
        },
        {
          "name": "Pressure stimuli",
          "type": "DEVICE"
        },
        {
          "name": "Pain ratings",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Conditioned pain modulation (CPM) response",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Hormonal assessment",
          "type": "BIOLOGICAL"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "BEHAVIORAL",
        "BIOLOGICAL"
      ],
      "sponsor": "Washington University School of Medicine",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "12 Years",
        "maximum_age": "45 Years",
        "sex": "FEMALE",
        "summary": "12 Years to 45 Years · Female only"
      },
      "enrollment_count": 120,
      "start_date": "2025-02-12",
      "completion_date": "2030-01-01",
      "has_results": false,
      "last_update_posted_date": "2026-07-13",
      "last_synced_at": "2026-09-04T16:23:54.440Z",
      "location_count": 1,
      "location_summary": "St Louis, Missouri",
      "locations": [
        {
          "city": "St Louis",
          "state": "Missouri"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06785129"
    }
  ]
}