{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Thoracic+spinal+manipulation",
    "query": {
      "intervention": "Thoracic spinal manipulation"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 30,
    "total_pages": 3,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Thoracic+spinal+manipulation&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-08T13:29:38.547Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT04972929",
      "title": "Effects of Chiropractic Care on Cytokine Levels in Multiple Sclerosis",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Multiple Sclerosis, Relapsing-Remitting"
      ],
      "interventions": [
        {
          "name": "Spinal Manipulation",
          "type": "OTHER"
        },
        {
          "name": "Sham Spinal Manipulation",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Alabama at Birmingham",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "55 Years",
        "sex": "ALL",
        "summary": "18 Years to 55 Years"
      },
      "enrollment_count": 26,
      "start_date": "2023-09-15",
      "completion_date": "2025-03-12",
      "has_results": true,
      "last_update_posted_date": "2026-07-20",
      "last_synced_at": "2026-09-08T13:29:38.547Z",
      "location_count": 1,
      "location_summary": "Birmingham, Alabama",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04972929"
    },
    {
      "nct_id": "NCT02111278",
      "title": "Lumbar Manipulation and Exercise for the Treatment of Acute Low Back Pain in Adolescents",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Low Back Pain"
      ],
      "interventions": [
        {
          "name": "Lumbar Manipulation",
          "type": "OTHER"
        },
        {
          "name": "Sham Manipulation",
          "type": "OTHER"
        },
        {
          "name": "Physical Therapy",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Nationwide Children's Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "13 Years",
        "maximum_age": "17 Years",
        "sex": "ALL",
        "summary": "13 Years to 17 Years"
      },
      "enrollment_count": 35,
      "start_date": "2012-05",
      "completion_date": "2014-12",
      "has_results": false,
      "last_update_posted_date": "2014-12-23",
      "last_synced_at": "2026-09-08T13:29:38.547Z",
      "location_count": 3,
      "location_summary": "Columbus, Ohio • Westerville, Ohio",
      "locations": [
        {
          "city": "Columbus",
          "state": "Ohio"
        },
        {
          "city": "Columbus",
          "state": "Ohio"
        },
        {
          "city": "Westerville",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02111278"
    },
    {
      "nct_id": "NCT02708953",
      "title": "Thoracic Spine Thrust Manipulation for Cervicogenic Headaches: A Randomized Clinical Trial",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Headache Disorders, Secondary"
      ],
      "interventions": [
        {
          "name": "Thoracic manipulation (Manipulation Group)",
          "type": "PROCEDURE"
        },
        {
          "name": "Thoracic Manipulation (Control wait-list)",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "University of Colorado, Denver",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "60 Years",
        "sex": "ALL",
        "summary": "18 Years to 60 Years"
      },
      "enrollment_count": 48,
      "start_date": "2016-05",
      "completion_date": "2019-09-19",
      "has_results": false,
      "last_update_posted_date": "2021-02-04",
      "last_synced_at": "2026-09-08T13:29:38.547Z",
      "location_count": 1,
      "location_summary": "Aurora, Colorado",
      "locations": [
        {
          "city": "Aurora",
          "state": "Colorado"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02708953"
    },
    {
      "nct_id": "NCT02373605",
      "title": "Spinal Manipulation and Dry Needling Versus Conventional Physical Therapy in Patients With Cervicogenic Headache",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Cervicogenic Headaches"
      ],
      "interventions": [
        {
          "name": "Dry Needling,Thrust Manipulation",
          "type": "OTHER"
        },
        {
          "name": "Exercise,Non-thrust Mobilization",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Alabama Physical Therapy & Acupuncture",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 142,
      "start_date": "2015-02",
      "completion_date": "2018-05-15",
      "has_results": false,
      "last_update_posted_date": "2018-06-06",
      "last_synced_at": "2026-09-08T13:29:38.547Z",
      "location_count": 1,
      "location_summary": "Montgomery, Alabama",
      "locations": [
        {
          "city": "Montgomery",
          "state": "Alabama"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02373605"
    },
    {
      "nct_id": "NCT01760590",
      "title": "The Effects of Thoracic Spine Manipulation in Individuals With Non-traumatic Cervical Pain",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Neck Pain",
        "Cervical Pain"
      ],
      "interventions": [
        {
          "name": "Manual Manipulation",
          "type": "PROCEDURE"
        },
        {
          "name": "Mobilization",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Keystone Rehabilitation Systems",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "60 Years",
        "sex": "ALL",
        "summary": "18 Years to 60 Years"
      },
      "enrollment_count": 100,
      "start_date": "2012-12",
      "completion_date": "2013-12",
      "has_results": false,
      "last_update_posted_date": "2013-01-04",
      "last_synced_at": "2026-09-08T13:29:38.547Z",
      "location_count": 2,
      "location_summary": "Bridgeville, Pennsylvania • Pittsburgh, Pennsylvania",
      "locations": [
        {
          "city": "Bridgeville",
          "state": "Pennsylvania"
        },
        {
          "city": "Pittsburgh",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01760590"
    },
    {
      "nct_id": "NCT02972710",
      "title": "A Comparison of Two Thoracic Manipulation Techniques to Improve Neck Pain",
      "overall_status": "SUSPENDED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Neck Pain"
      ],
      "interventions": [
        {
          "name": "Supine thoracic spine thrust manipulation",
          "type": "OTHER"
        },
        {
          "name": "Seated thoracic spine thrust manipulation",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Northern Arizona University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "20 Years",
        "maximum_age": "50 Years",
        "sex": "ALL",
        "summary": "20 Years to 50 Years"
      },
      "enrollment_count": 76,
      "start_date": "2016-11",
      "completion_date": "2018-11",
      "has_results": false,
      "last_update_posted_date": "2018-03-13",
      "last_synced_at": "2026-09-08T13:29:38.547Z",
      "location_count": 1,
      "location_summary": "Flagstaff, Arizona",
      "locations": [
        {
          "city": "Flagstaff",
          "state": "Arizona"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02972710"
    },
    {
      "nct_id": "NCT04142177",
      "title": "Sequential and Comparative Evaluation of Pain Treatment Effectiveness Response",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Chronic Low Back Pain"
      ],
      "interventions": [
        {
          "name": "Pain EASE",
          "type": "OTHER"
        },
        {
          "name": "Tailored exercise",
          "type": "PROCEDURE"
        },
        {
          "name": "Continued Care and Active Monitoring",
          "type": "OTHER"
        },
        {
          "name": "Cognitive Behavioral Therapy (CBT)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Spinal Manipulation Therapy (SMT)",
          "type": "PROCEDURE"
        },
        {
          "name": "Yoga",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "OTHER",
        "PROCEDURE",
        "BEHAVIORAL"
      ],
      "sponsor": "VA Office of Research and Development",
      "sponsor_class": "FED",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 2529,
      "start_date": "2022-06-13",
      "completion_date": "2027-06-30",
      "has_results": false,
      "last_update_posted_date": "2026-05-04",
      "last_synced_at": "2026-09-08T13:29:38.547Z",
      "location_count": 19,
      "location_summary": "Phoenix, Arizona • Loma Linda, California • Long Beach, California + 16 more",
      "locations": [
        {
          "city": "Phoenix",
          "state": "Arizona"
        },
        {
          "city": "Loma Linda",
          "state": "California"
        },
        {
          "city": "Long Beach",
          "state": "California"
        },
        {
          "city": "Palo Alto",
          "state": "California"
        },
        {
          "city": "Aurora",
          "state": "Colorado"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04142177"
    },
    {
      "nct_id": "NCT03017534",
      "title": "Non-Specific Effects of Manual Therapy",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Musculoskeletal Manipulations",
        "Placebo Effect"
      ],
      "interventions": [
        {
          "name": "Spinal Manual Therapy",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Shenandoah University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "18 Years to 70 Years"
      },
      "enrollment_count": 24,
      "start_date": "2017-01",
      "completion_date": "2017-10",
      "has_results": false,
      "last_update_posted_date": "2017-10-09",
      "last_synced_at": "2026-09-08T13:29:38.547Z",
      "location_count": 1,
      "location_summary": "Winchester, Virginia",
      "locations": [
        {
          "city": "Winchester",
          "state": "Virginia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03017534"
    },
    {
      "nct_id": "NCT01530321",
      "title": "Cervicogenic Headache Dose-Response",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1",
        "PHASE2"
      ],
      "conditions": [
        "Cervicogenic Headache"
      ],
      "interventions": [
        {
          "name": "Spinal Manipulation",
          "type": "OTHER"
        },
        {
          "name": "Light Massage",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Western States",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 256,
      "start_date": "2012-08",
      "completion_date": "2016-08",
      "has_results": false,
      "last_update_posted_date": "2018-11-20",
      "last_synced_at": "2026-09-08T13:29:38.547Z",
      "location_count": 2,
      "location_summary": "Bloomington, Minnesota • Portland, Oregon",
      "locations": [
        {
          "city": "Bloomington",
          "state": "Minnesota"
        },
        {
          "city": "Portland",
          "state": "Oregon"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01530321"
    },
    {
      "nct_id": "NCT02036905",
      "title": "Cervical and Upper Thoracic Mobilization and Manipulation for Mechanical Neck Pain",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Neck Pain"
      ],
      "interventions": [
        {
          "name": "Cervical and thoracic mobilization",
          "type": "OTHER"
        },
        {
          "name": "cervical and thoracic manipulation",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Youngstown State University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "70 Years",
        "sex": "ALL",
        "summary": "18 Years to 70 Years"
      },
      "enrollment_count": 20,
      "start_date": "2013-07",
      "completion_date": "2015-08",
      "has_results": false,
      "last_update_posted_date": "2016-01-26",
      "last_synced_at": "2026-09-08T13:29:38.547Z",
      "location_count": 2,
      "location_summary": "Solon, Ohio • Havertown, Pennsylvania",
      "locations": [
        {
          "city": "Solon",
          "state": "Ohio"
        },
        {
          "city": "Havertown",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02036905"
    }
  ]
}