{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Tidal+breathing",
    "query": {
      "intervention": "Tidal breathing"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 156,
    "total_pages": 16,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Tidal+breathing&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-06T20:18:34.261Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT01557920",
      "title": "The Effects of General Anesthetics on Upper Airway Collapsibility in Healthy Subjects",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Airway Complication of Anaesthesia",
        "Healthy"
      ],
      "interventions": [
        {
          "name": "Propofol",
          "type": "DRUG"
        },
        {
          "name": "Sevoflurane",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Massachusetts General Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "45 Years",
        "sex": "ALL",
        "summary": "18 Years to 45 Years"
      },
      "enrollment_count": 18,
      "start_date": "2013-01",
      "completion_date": "2014-03",
      "has_results": true,
      "last_update_posted_date": "2016-09-13",
      "last_synced_at": "2026-09-06T20:18:34.261Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01557920"
    },
    {
      "nct_id": "NCT00127491",
      "title": "Mechanical Ventilation, Directed by Esophageal Pressure Measurements, in Patients With Acute Lung Injury",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Acute Lung Injury",
        "Acute Respiratory Distress Syndrome"
      ],
      "interventions": [
        {
          "name": "Placement of an esophageal balloon measurements",
          "type": "PROCEDURE"
        },
        {
          "name": "Low tidal volume ventilation",
          "type": "OTHER"
        },
        {
          "name": "Transpulmonary pressure-directed ventilation (EPVent)",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "PROCEDURE",
        "OTHER"
      ],
      "sponsor": "Beth Israel Deaconess Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 63,
      "start_date": "2004-05",
      "completion_date": "2010-05",
      "has_results": false,
      "last_update_posted_date": "2017-02-27",
      "last_synced_at": "2026-09-06T20:18:34.261Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00127491"
    },
    {
      "nct_id": "NCT02507973",
      "title": "Study of Airway Pressure Release Ventilation and Intracranial Pressure in Patients With Severe Traumatic Brain Injury",
      "overall_status": "TERMINATED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Injury, Brain, Traumatic",
        "Traumatic Brain Injury"
      ],
      "interventions": [
        {
          "name": "Airway Pressure Release Ventilation",
          "type": "OTHER"
        },
        {
          "name": "Low Tidal Volume Ventilation",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Maryland, Baltimore",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "14 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "14 Years and older"
      },
      "enrollment_count": 8,
      "start_date": "2015-07",
      "completion_date": "2018-04",
      "has_results": true,
      "last_update_posted_date": "2022-01-28",
      "last_synced_at": "2026-09-06T20:18:34.261Z",
      "location_count": 1,
      "location_summary": "Baltimore, Maryland",
      "locations": [
        {
          "city": "Baltimore",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02507973"
    },
    {
      "nct_id": "NCT03840486",
      "title": "Pre-oxygenation With Real Time End-tidal Oxygen Measurements Versus Single Breath Measurements",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Rapid Sequence Intubation"
      ],
      "interventions": [
        {
          "name": "Non-rebreather mask (NRBM)",
          "type": "DEVICE"
        },
        {
          "name": "Non-invasive ventilator mask (NIV)",
          "type": "DEVICE"
        },
        {
          "name": "Nasal cannula EtO2 sensor",
          "type": "DEVICE"
        },
        {
          "name": "Oxygen (NRBM)",
          "type": "DRUG"
        },
        {
          "name": "Oxygen (NIV)",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "DRUG"
      ],
      "sponsor": "Emory University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 105,
      "start_date": "2019-09-24",
      "completion_date": "2023-10-20",
      "has_results": true,
      "last_update_posted_date": "2025-06-13",
      "last_synced_at": "2026-09-06T20:18:34.261Z",
      "location_count": 2,
      "location_summary": "Atlanta, Georgia",
      "locations": [
        {
          "city": "Atlanta",
          "state": "Georgia"
        },
        {
          "city": "Atlanta",
          "state": "Georgia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03840486"
    },
    {
      "nct_id": "NCT07204990",
      "title": "BELUGA: Better to Exchange ETT for LMA Before Extubation in Children Under General Anaesthesia",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Endotracheal Extubation",
        "Airway Anesthesia",
        "Paediatric"
      ],
      "interventions": [
        {
          "name": "Direct removal of endotracheal tube",
          "type": "PROCEDURE"
        },
        {
          "name": "Laryngeal mask airway inserted following deep extubation",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Telethon Kids Institute",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "0 Years",
        "maximum_age": "16 Years",
        "sex": "ALL",
        "summary": "0 Years to 16 Years"
      },
      "enrollment_count": 1400,
      "start_date": "2026-02-06",
      "completion_date": "2029-02-28",
      "has_results": false,
      "last_update_posted_date": "2026-06-01",
      "last_synced_at": "2026-09-06T20:18:34.261Z",
      "location_count": 2,
      "location_summary": "Winston-Salem, North Carolina • Philadelphia, Pennsylvania",
      "locations": [
        {
          "city": "Winston-Salem",
          "state": "North Carolina"
        },
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07204990"
    },
    {
      "nct_id": "NCT07362641",
      "title": "Clinical Validation of Non-Contact Vital Signs",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Vital Sign Evaluation"
      ],
      "interventions": [
        {
          "name": "SmartSpectra Vital Signs Monitor measurement",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Presage Technologies, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "75 Years",
        "sex": "ALL",
        "summary": "18 Years to 75 Years"
      },
      "enrollment_count": 111,
      "start_date": "2025-03-28",
      "completion_date": "2025-04-21",
      "has_results": true,
      "last_update_posted_date": "2026-08-24",
      "last_synced_at": "2026-09-06T20:18:34.261Z",
      "location_count": 1,
      "location_summary": "Houston, Texas",
      "locations": [
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07362641"
    },
    {
      "nct_id": "NCT01865851",
      "title": "Comparison of the Classic Face Mask Versus NuMask for Preoxygenation",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Inspired Oxygen (FIO2), End-tidal Oxygen (ETO2), End-tidal Carbon Dioxide (ETCO2) and Respiratory Rate (RR) Will be Measured Every 30 Seconds"
      ],
      "interventions": [
        {
          "name": "Classic Face Mask and NuMask",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Nimmagadda, Usharani, M.D.",
      "sponsor_class": "INDIV",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 30,
      "start_date": "2013-05",
      "completion_date": "2018-06",
      "has_results": false,
      "last_update_posted_date": "2017-09-14",
      "last_synced_at": "2026-09-06T20:18:34.261Z",
      "location_count": 1,
      "location_summary": "Chicago, Illinois",
      "locations": [
        {
          "city": "Chicago",
          "state": "Illinois"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01865851"
    },
    {
      "nct_id": "NCT01522222",
      "title": "Study to Determine if Using Ventilation During Open Heart Surgery Improves Lung Outcomes",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Coronary Artery Disease",
        "Heart Failure"
      ],
      "interventions": [
        {
          "name": "continuous, mechanical ventilatory support",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Aurora BayCare Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 40,
      "start_date": "2010-07",
      "completion_date": "2015-09-29",
      "has_results": false,
      "last_update_posted_date": "2018-12-14",
      "last_synced_at": "2026-09-06T20:18:34.261Z",
      "location_count": 1,
      "location_summary": "Green Bay, Wisconsin",
      "locations": [
        {
          "city": "Green Bay",
          "state": "Wisconsin"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01522222"
    },
    {
      "nct_id": "NCT04413643",
      "title": "NIV for COPD: Hospital to Home",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Pulmonary Disease, Chronic Obstructive",
        "Noninvasive Ventilation"
      ],
      "interventions": [
        {
          "name": "Noninvasive Ventilation",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "San Francisco Veterans Affairs Medical Center",
      "sponsor_class": "FED",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 6,
      "start_date": "2019-05-09",
      "completion_date": "2024-04-01",
      "has_results": false,
      "last_update_posted_date": "2024-04-25",
      "last_synced_at": "2026-09-06T20:18:34.261Z",
      "location_count": 1,
      "location_summary": "San Francisco, California",
      "locations": [
        {
          "city": "San Francisco",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04413643"
    },
    {
      "nct_id": "NCT05298709",
      "title": "Functional Magnetic Resonance Imaging (fMRI) Vascular Reactivity in Cerebral Cavernous Malformations (CCM)",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Cerebral Cavernous Malformation"
      ],
      "interventions": [
        {
          "name": "Hyperventilation and CO2 challenge",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of New Mexico",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 5,
      "start_date": "2023-06-15",
      "completion_date": "2024-07-17",
      "has_results": false,
      "last_update_posted_date": "2025-06-11",
      "last_synced_at": "2026-09-06T20:18:34.261Z",
      "location_count": 1,
      "location_summary": "Albuquerque, New Mexico",
      "locations": [
        {
          "city": "Albuquerque",
          "state": "New Mexico"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05298709"
    }
  ]
}