{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Tidal+volume+used+in+mechanical+ventilation",
    "query": {
      "intervention": "Tidal volume used in mechanical ventilation"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 11,
    "total_pages": 2,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Tidal+volume+used+in+mechanical+ventilation&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-27T15:24:12.373Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT05350332",
      "title": "Effects of Lung Volume on Upper Airway Patency During Drug Induced Sleep Endoscopy",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Obstructive Sleep Apnea"
      ],
      "interventions": [
        {
          "name": "Negative Pressure Ventilator",
          "type": "DEVICE"
        },
        {
          "name": "Pulmonary Function Testing (PFT)",
          "type": "DEVICE"
        },
        {
          "name": "Transcutaneous Phrenic Nerve Stimulation",
          "type": "DEVICE"
        },
        {
          "name": "Percutaneous Phrenic Nerve Stimulation",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Emory University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 151,
      "start_date": "2022-06-30",
      "completion_date": "2027-06",
      "has_results": false,
      "last_update_posted_date": "2026-08-26",
      "last_synced_at": "2026-09-27T15:24:12.373Z",
      "location_count": 1,
      "location_summary": "Atlanta, Georgia",
      "locations": [
        {
          "city": "Atlanta",
          "state": "Georgia"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05350332"
    },
    {
      "nct_id": "NCT07656259",
      "title": "COMPARE-VENT Feasibility Pilot Study",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Respiration Failure",
        "Cardio Vascular Disease",
        "Cardiogenic Pulmonary Oedema",
        "Critical Illness",
        "Mechanical Ventilation",
        "Cardiogenic Shock",
        "Cardiopulmonary"
      ],
      "interventions": [
        {
          "name": "Volume Controlled Mode",
          "type": "OTHER"
        },
        {
          "name": "Pressure Controlled Mode",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Mayo Clinic",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 75,
      "start_date": "2026-07-01",
      "completion_date": "2027-06-30",
      "has_results": false,
      "last_update_posted_date": "2026-08-10",
      "last_synced_at": "2026-09-27T15:24:12.373Z",
      "location_count": 1,
      "location_summary": "Rochester, Minnesota",
      "locations": [
        {
          "city": "Rochester",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07656259"
    },
    {
      "nct_id": "NCT02507973",
      "title": "Study of Airway Pressure Release Ventilation and Intracranial Pressure in Patients With Severe Traumatic Brain Injury",
      "overall_status": "TERMINATED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Injury, Brain, Traumatic",
        "Traumatic Brain Injury"
      ],
      "interventions": [
        {
          "name": "Airway Pressure Release Ventilation",
          "type": "OTHER"
        },
        {
          "name": "Low Tidal Volume Ventilation",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Maryland, Baltimore",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "14 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "14 Years and older"
      },
      "enrollment_count": 8,
      "start_date": "2015-07",
      "completion_date": "2018-04",
      "has_results": true,
      "last_update_posted_date": "2022-01-28",
      "last_synced_at": "2026-09-27T15:24:12.373Z",
      "location_count": 1,
      "location_summary": "Baltimore, Maryland",
      "locations": [
        {
          "city": "Baltimore",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02507973"
    },
    {
      "nct_id": "NCT02367170",
      "title": "Project 4A: Inspiratory Muscle Training and Diaphragm Strength",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1",
        "PHASE2"
      ],
      "conditions": [
        "Sepsis"
      ],
      "interventions": [
        {
          "name": "Bilateral phrenic nerve stimulation and measurement of transdiaphragmatic pressure",
          "type": "PROCEDURE"
        },
        {
          "name": "Midazolam",
          "type": "DRUG"
        },
        {
          "name": "Volitional Measurement of Maximal Inspiratory Pressure (MIP)",
          "type": "PROCEDURE"
        },
        {
          "name": "Inspiratory Muscle Strength Training (IMST)",
          "type": "DEVICE"
        },
        {
          "name": "SHAM Inspiratory Muscle Strength Training (IMST)",
          "type": "DEVICE"
        },
        {
          "name": "Diaphragm thickness measurement",
          "type": "PROCEDURE"
        },
        {
          "name": "Blood and Urine samples",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "PROCEDURE",
        "DRUG",
        "DEVICE",
        "OTHER"
      ],
      "sponsor": "University of Florida",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 1,
      "start_date": "2015-03",
      "completion_date": "2015-07",
      "has_results": true,
      "last_update_posted_date": "2018-05-07",
      "last_synced_at": "2026-09-27T15:24:12.373Z",
      "location_count": 1,
      "location_summary": "Gainesville, Florida",
      "locations": [
        {
          "city": "Gainesville",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02367170"
    },
    {
      "nct_id": "NCT00750204",
      "title": "Airway Pressure Release Ventilation in Acute Lung Injury",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Acute Lung Injury",
        "Acute Respiratory Distress Syndrome",
        "Mechanical Ventilation"
      ],
      "interventions": [
        {
          "name": "APRV",
          "type": "DEVICE"
        },
        {
          "name": "Conventional MV",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Johns Hopkins University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 2,
      "start_date": "2008-07",
      "completion_date": "2008-10-15",
      "has_results": true,
      "last_update_posted_date": "2017-05-15",
      "last_synced_at": "2026-09-27T15:24:12.373Z",
      "location_count": 1,
      "location_summary": "Baltimore, Maryland",
      "locations": [
        {
          "city": "Baltimore",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00750204"
    },
    {
      "nct_id": "NCT05989880",
      "title": "Pilot Feasibility Trial of the SafeLM Supraglottic Airway (SGA)",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Anesthesia"
      ],
      "interventions": [
        {
          "name": "SafeLM as a supraglottic airway device with video capability",
          "type": "DEVICE"
        },
        {
          "name": "SafeLM as a supraglottic airway device without video capability",
          "type": "DEVICE"
        },
        {
          "name": "SafeLM as a conduit for intubation using an endotracheal tube with video capability",
          "type": "DEVICE"
        },
        {
          "name": "SafeLM as a conduit for intubation using a bougie with video capability",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "The University of Texas Health Science Center, Houston",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 60,
      "start_date": "2023-09-19",
      "completion_date": "2025-12-02",
      "has_results": false,
      "last_update_posted_date": "2024-12-10",
      "last_synced_at": "2026-09-27T15:24:12.373Z",
      "location_count": 1,
      "location_summary": "Houston, Texas",
      "locations": [
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05989880"
    },
    {
      "nct_id": "NCT06895148",
      "title": "ADHERE-LPV Advancing Delivery of High-Quality Evidence-Based Respiratory Efforts in Lung-Protective Ventilation",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Ventilation"
      ],
      "interventions": [
        {
          "name": "New ventilator",
          "type": "DEVICE"
        },
        {
          "name": "control ventilator",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "University of Minnesota",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 1500,
      "start_date": "2025-07-01",
      "completion_date": "2026-12-31",
      "has_results": false,
      "last_update_posted_date": "2026-09-22",
      "last_synced_at": "2026-09-27T15:24:12.373Z",
      "location_count": 1,
      "location_summary": "Minneapolis, Minnesota",
      "locations": [
        {
          "city": "Minneapolis",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06895148"
    },
    {
      "nct_id": "NCT00412308",
      "title": "A Comparison of High vs. Low Tidal Volumes in Ventilator Weaning for Individuals With Cervical Spinal Cord Injuries",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Spinal Cord Injury",
        "Respiratory Insufficiency"
      ],
      "interventions": [
        {
          "name": "Tidal volume used in mechanical ventilation",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Craig Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "55 Years",
        "sex": "ALL",
        "summary": "18 Years to 55 Years"
      },
      "enrollment_count": 34,
      "start_date": "2006-12",
      "completion_date": "2010-08",
      "has_results": false,
      "last_update_posted_date": "2011-06-28",
      "last_synced_at": "2026-09-27T15:24:12.373Z",
      "location_count": 1,
      "location_summary": "Englewood, Colorado",
      "locations": [
        {
          "city": "Englewood",
          "state": "Colorado"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00412308"
    },
    {
      "nct_id": "NCT04281017",
      "title": "Effect of Position and Anesthetic Choice in Intraocular Pressure in Robotic GYN (Gynecologic) Oncology Patients",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Intraocular Pressure",
        "Oncology"
      ],
      "interventions": [
        {
          "name": "TIVA",
          "type": "DRUG"
        },
        {
          "name": "Balanced anesthesia",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "University of Florida",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "99 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 99 Years · Female only"
      },
      "enrollment_count": 22,
      "start_date": "2020-11-10",
      "completion_date": "2026-02-20",
      "has_results": true,
      "last_update_posted_date": "2026-07-23",
      "last_synced_at": "2026-09-27T15:24:12.373Z",
      "location_count": 1,
      "location_summary": "Gainesville, Florida",
      "locations": [
        {
          "city": "Gainesville",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04281017"
    },
    {
      "nct_id": "NCT04382625",
      "title": "Hydroxychloroquine in SARS-CoV-2 (COVID-19) Pneumonia Trial",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "SARS-CoV-2 Pneumonia",
        "COVID-19"
      ],
      "interventions": [
        {
          "name": "Hydroxychloroquine",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Kootenai Health",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 0,
      "start_date": "2020-10",
      "completion_date": "2022-06-01",
      "has_results": false,
      "last_update_posted_date": "2021-02-05",
      "last_synced_at": "2026-09-27T15:24:12.373Z",
      "location_count": 1,
      "location_summary": "Coeur d'Alene, Idaho",
      "locations": [
        {
          "city": "Coeur d'Alene",
          "state": "Idaho"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04382625"
    }
  ]
}