{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Timolol+eye+drops+0.5%25", "query": { "intervention": "Timolol eye drops 0.5%" }, "page_size": 10 }, "pagination": { "page": 1, "page_size": 10, "total_count": 61, "total_pages": 7, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Timolol+eye+drops+0.5%25&page=2&page_size=10", "previous_page_url": null }, "source": "remote", "last_synced_at": "2026-09-24T12:19:04.714Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT02358369", "title": "Dose-Ranging Study of the Bimatoprost Ocular Insert", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Primary Open-Angle Glaucoma", "Ocular Hypertension" ], "interventions": [ { "name": "Bimatoprost", "type": "DRUG" }, { "name": "Timolol 0.5%", "type": "DRUG" }, { "name": "Placebo Ocular Insert", "type": "DEVICE" }, { "name": "Placebo Eye Drops", "type": "DRUG" } ], "intervention_types": [ "DRUG", "DEVICE" ], "sponsor": "ForSight Vision5, Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 156, "start_date": "2015-01-19", "completion_date": "2015-10-07", "has_results": true, "last_update_posted_date": "2020-06-04", "last_synced_at": "2026-09-24T12:19:04.714Z", "location_count": 10, "location_summary": "Fayetteville, Arkansas • Artesia, California • Newport Beach, California + 7 more", "locations": [ { "city": "Fayetteville", "state": "Arkansas" }, { "city": "Artesia", "state": "California" }, { "city": "Newport Beach", "state": "California" }, { "city": "Morrow", "state": "Georgia" }, { "city": "Charlotte", "state": "North Carolina" } ], "official_url": "https://clinicaltrials.gov/study/NCT02358369" }, { "nct_id": "NCT05913232", "title": "Study of Safety and Efficacy of H-1337 in Subjects With Primary Open Angle Glaucoma or Ocular Hypertension", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Glaucoma Open-Angle Primary", "Ocular Hypertension" ], "interventions": [ { "name": "H-1337 0.6%", "type": "DRUG" }, { "name": "H-1337 1.0%", "type": "DRUG" }, { "name": "H-1337 Placebo", "type": "DRUG" }, { "name": "Timolol 0.5%", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "D. Western Therapeutics Institute, Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 201, "start_date": "2023-08-28", "completion_date": "2024-08-29", "has_results": true, "last_update_posted_date": "2025-08-27", "last_synced_at": "2026-09-24T12:19:04.714Z", "location_count": 9, "location_summary": "Glendale, California • Colorado Springs, Colorado • Lakeland, Florida + 6 more", "locations": [ { "city": "Glendale", "state": "California" }, { "city": "Colorado Springs", "state": "Colorado" }, { "city": "Lakeland", "state": "Florida" }, { "city": "Largo", "state": "Florida" }, { "city": "Albany", "state": "Georgia" } ], "official_url": "https://clinicaltrials.gov/study/NCT05913232" }, { "nct_id": "NCT07218796", "title": "Evaluation of the Safety and Efficacy of the Bimatoprost Implant System Used in Combination With the SpyGlass IOL Compared to Timolol Ophthalmic Solution (Rhone)", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Cataract", "Glaucoma", "Ocular Hypertension" ], "interventions": [ { "name": "Bimatoprost Implant System", "type": "DRUG" }, { "name": "SpyGlass IOL", "type": "DEVICE" }, { "name": "Timolol Maleate Ophthalmic Solution, 0.5%", "type": "DRUG" }, { "name": "Commercial IOL", "type": "DEVICE" } ], "intervention_types": [ "DRUG", "DEVICE" ], "sponsor": "SpyGlass Pharma, Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "22 Years", "maximum_age": null, "sex": "ALL", "summary": "22 Years and older" }, "enrollment_count": 400, "start_date": "2025-10-28", "completion_date": "2031-05-31", "has_results": false, "last_update_posted_date": "2025-10-20", "last_synced_at": "2026-09-24T12:19:04.714Z", "location_count": 1, "location_summary": "San Antonio, Texas", "locations": [ { "city": "San Antonio", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT07218796" }, { "nct_id": "NCT02097719", "title": "Efficacy and Safety Study of Bimatoprost 0.01% Alone Compared With Travoprost 0.004% and Timolol 0.5% in Subjects With Glaucoma or Ocular Hypertension", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Glaucoma", "Ocular Hypertension" ], "interventions": [ { "name": "bimatoprost 0.01%", "type": "DRUG" }, { "name": "travoprost 0.004%", "type": "DRUG" }, { "name": "timolol 0.5%", "type": "DRUG" }, { "name": "hypromellose 0.3%", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Allergan", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 100, "start_date": "2014-05", "completion_date": "2014-12", "has_results": true, "last_update_posted_date": "2016-01-14", "last_synced_at": "2026-09-24T12:19:04.714Z", "location_count": 1, "location_summary": "Racine, Wisconsin", "locations": [ { "city": "Racine", "state": "Wisconsin" } ], "official_url": "https://clinicaltrials.gov/study/NCT02097719" }, { "nct_id": "NCT04742283", "title": "Multicenter Study Assessing the Efficacy and Safety of DE-126 Ophthalmic Solution 0.002% Compared With Timolol Maleate Ophthalmic Solution 0.5% in Subjects With Primary Open Angle Glaucoma or Ocular Hypertension", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Primary Open Angle Glaucoma", "Ocular Hypertension" ], "interventions": [ { "name": "DE-126 Ophthalmic Solution 0.002% QD", "type": "DRUG" }, { "name": "Timolol Maleate Ophthalmic Solution 0.5% BID", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Santen Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 323, "start_date": "2020-12-17", "completion_date": "2021-12-07", "has_results": true, "last_update_posted_date": "2023-06-22", "last_synced_at": "2026-09-24T12:19:04.714Z", "location_count": 41, "location_summary": "Chandler, Arizona • Phoenix, Arizona • Sun City, Arizona + 34 more", "locations": [ { "city": "Chandler", "state": "Arizona" }, { "city": "Phoenix", "state": "Arizona" }, { "city": "Sun City", "state": "Arizona" }, { "city": "Glendale", "state": "California" }, { "city": "Los Angeles", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT04742283" }, { "nct_id": "NCT07168902", "title": "Phase 2 Study of BL1107 Eye Drops vs. Timolol in Adults With Primary Open Angle Glaucoma or Ocular Hypertension", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Glaucoma" ], "interventions": [ { "name": "BL1107 Low dose", "type": "DRUG" }, { "name": "BL1107 High dose", "type": "DRUG" }, { "name": "Timolol maleate 0.5%", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Bausch & Lomb Incorporated", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 252, "start_date": "2025-10-24", "completion_date": "2026-05-18", "has_results": false, "last_update_posted_date": "2026-07-22", "last_synced_at": "2026-09-24T12:19:04.714Z", "location_count": 14, "location_summary": "Glendale, California • Newport Beach, California • Pasadena, California + 11 more", "locations": [ { "city": "Glendale", "state": "California" }, { "city": "Newport Beach", "state": "California" }, { "city": "Pasadena", "state": "California" }, { "city": "Fort Myers", "state": "Florida" }, { "city": "Jacksonville", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT07168902" }, { "nct_id": "NCT03691649", "title": "A Phase III Study Assessing the Efficacy and Safety of DE-117 Ophthalmic Solution Compared With Timolol Maleate Ophthalmic Solution 0.5% in Subjects With Glaucoma or Ocular Hypertension - Spectrum 3 Study", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Glaucoma and Ocular Hypertension" ], "interventions": [ { "name": "DE-117 Ophthalmic Solution", "type": "DRUG" }, { "name": "Timolol Maleate Ophthalmic Solution 0.5%", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Santen Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "12 Months", "maximum_age": null, "sex": "ALL", "summary": "12 Months and older" }, "enrollment_count": 426, "start_date": "2018-09-14", "completion_date": "2020-09-03", "has_results": true, "last_update_posted_date": "2023-08-30", "last_synced_at": "2026-09-24T12:19:04.714Z", "location_count": 47, "location_summary": "Phoenix, Arizona • Sun City, Arizona • Burbank, California + 40 more", "locations": [ { "city": "Phoenix", "state": "Arizona" }, { "city": "Sun City", "state": "Arizona" }, { "city": "Burbank", "state": "California" }, { "city": "Los Angeles", "state": "California" }, { "city": "Mission Hills", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT03691649" }, { "nct_id": "NCT07075718", "title": "Phase 2 Trial to Evaluate the Safety and Efficacy of the Second Generation Travoprost Intracameral Implant", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Glaucoma" ], "interventions": [ { "name": "Gen 2 Travoprost Intracameral Implant", "type": "DRUG" }, { "name": "Timolol eye drops 0.5%", "type": "DRUG" }, { "name": "Sham Procedure", "type": "PROCEDURE" }, { "name": "Placebo eye drops", "type": "OTHER" } ], "intervention_types": [ "DRUG", "PROCEDURE", "OTHER" ], "sponsor": "Glaukos Corporation", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 110, "start_date": "2025-06-12", "completion_date": "2032-03", "has_results": false, "last_update_posted_date": "2026-09-17", "last_synced_at": "2026-09-24T12:19:04.714Z", "location_count": 3, "location_summary": "Grand Junction, Colorado • Oklahoma City, Oklahoma • El Paso, Texas", "locations": [ { "city": "Grand Junction", "state": "Colorado" }, { "city": "Oklahoma City", "state": "Oklahoma" }, { "city": "El Paso", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT07075718" }, { "nct_id": "NCT00620256", "title": "Adjunctive Study of AL-37807 Ophthalmic Suspension", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Open-Angle Glaucoma", "Ocular Hypertension" ], "interventions": [ { "name": "AL-37807 ophthalmic suspension, 0.1%", "type": "DRUG" }, { "name": "Timolol gel forming solution, 0.5%", "type": "DRUG" }, { "name": "AL-37807 ophthalmic solution vehicle", "type": "OTHER" }, { "name": "Latanoprost ophthalmic solution", "type": "DRUG" } ], "intervention_types": [ "DRUG", "OTHER" ], "sponsor": "Alcon Research", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 129, "start_date": "2007-11", "completion_date": "2008-07", "has_results": false, "last_update_posted_date": "2012-12-05", "last_synced_at": "2026-09-24T12:19:04.714Z", "location_count": 1, "location_summary": "Fort Worth, Texas", "locations": [ { "city": "Fort Worth", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT00620256" }, { "nct_id": "NCT04830397", "title": "Study to Evaluate QLS-101 Compared to Timolol Maleate Eye Drops in Subjects With High Eye Pressure (Glaucoma or Ocular Hypertension).", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Primary Open Angle Glaucoma", "Ocular Hypertension" ], "interventions": [ { "name": "QLS-101", "type": "DRUG" }, { "name": "Timolol Maleate", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Qlaris Bio, Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 84, "start_date": "2021-03-31", "completion_date": "2022-02-17", "has_results": false, "last_update_posted_date": "2025-01-17", "last_synced_at": "2026-09-24T12:19:04.714Z", "location_count": 1, "location_summary": "Albany, Georgia", "locations": [ { "city": "Albany", "state": "Georgia" } ], "official_url": "https://clinicaltrials.gov/study/NCT04830397" } ] }