{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Timolol+maleate&page=2", "query": { "intervention": "Timolol maleate", "page": 2 }, "page_size": 10 }, "pagination": { "page": 2, "page_size": 10, "total_count": 132, "total_pages": 14, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Timolol+maleate&page=3&page_size=10", "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Timolol+maleate&page=1&page_size=10" }, "source": "remote", "last_synced_at": "2026-10-01T05:09:14.807Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT07847073", "title": "Adaptive Optics OCT Evaluation of Rhopressa's Effects on the Retinal Ganglion Cells in Glaucoma Patients", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Open Angle Glaucoma (OAG)", "Glaucoma" ], "interventions": [ { "name": "Netarsudil 0.02% Ophthalmic Solution [RHOPRESSA]", "type": "DRUG" }, { "name": "Timolol Maleate 0.25% Ophthalmic Solution", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Brett King", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 13, "start_date": "2026-10", "completion_date": "2028-01", "has_results": false, "last_update_posted_date": "2026-09-29", "last_synced_at": "2026-10-01T05:09:14.807Z", "location_count": 1, "location_summary": "Bloomington, Indiana", "locations": [ { "city": "Bloomington", "state": "Indiana" } ], "official_url": "https://clinicaltrials.gov/study/NCT07847073" }, { "nct_id": "NCT02852057", "title": "Effectiveness and Safety of Timolol and Dorzolamide Loaded Contact Lenses", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Glaucoma" ], "interventions": [ { "name": "timolol maleate and dorzolamide hydrochloride", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "University of Florida", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 2, "start_date": "2018-01-18", "completion_date": "2021-08-10", "has_results": false, "last_update_posted_date": "2021-12-02", "last_synced_at": "2026-10-01T05:09:14.807Z", "location_count": 1, "location_summary": "Gainesville, Florida", "locations": [ { "city": "Gainesville", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT02852057" }, { "nct_id": "NCT01520116", "title": "Study of the Safety and Efficacy of ATS907 in Subjects With Primary Open Angle Glaucoma (POAG) and Ocular Hypertension", "overall_status": "UNKNOWN", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1", "PHASE2" ], "conditions": [ "Primary Open Angle Glaucoma", "Ocular Hypertension" ], "interventions": [ { "name": "Stage 1 - ATS907 - Dose 1", "type": "DRUG" }, { "name": "Stage 1 - ATS907 - Dose 2", "type": "DRUG" }, { "name": "Stage 1 - ATS907 - Dose 3", "type": "DRUG" }, { "name": "Stage 1 - ATS907 - Dose 4", "type": "DRUG" }, { "name": "Stage 1 - Vehicle", "type": "DRUG" }, { "name": "Stage 2 - ATS907 - Dose A - to be selected based on Stage 1", "type": "DRUG" }, { "name": "Stage 2 - ATS907 - Dose B - to be selected based on Stage 1", "type": "DRUG" }, { "name": "Timoptic", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Altheos, Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 180, "start_date": "2012-01", "completion_date": null, "has_results": false, "last_update_posted_date": "2012-11-01", "last_synced_at": "2026-10-01T05:09:14.807Z", "location_count": 5, "location_summary": "Artesia, California • Glendale, California • Saint Joseph, Michigan + 2 more", "locations": [ { "city": "Artesia", "state": "California" }, { "city": "Glendale", "state": "California" }, { "city": "Saint Joseph", "state": "Michigan" }, { "city": "Cleveland", "state": "Ohio" }, { "city": "San Antonio", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT01520116" }, { "nct_id": "NCT01426113", "title": "A Study of the Safety and Efficacy of Bimatoprost Ophthalmic Solution in Paediatric Patients With Glaucoma", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Glaucoma" ], "interventions": [ { "name": "bimatoprost ophthalmic solution formulation A", "type": "DRUG" }, { "name": "timolol ophthalmic solution", "type": "DRUG" }, { "name": "bimatoprost vehicle", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Allergan", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "2 Months", "maximum_age": "17 Years", "sex": "ALL", "summary": "2 Months to 17 Years" }, "enrollment_count": 6, "start_date": "2011-09", "completion_date": "2014-10", "has_results": true, "last_update_posted_date": "2015-10-02", "last_synced_at": "2026-10-01T05:09:14.807Z", "location_count": 1, "location_summary": "Louisville, Kentucky", "locations": [ { "city": "Louisville", "state": "Kentucky" } ], "official_url": "https://clinicaltrials.gov/study/NCT01426113" }, { "nct_id": "NCT00332072", "title": "Safety and Efficacy Study of Bimatoprost/Timolol Fixed Combination in Patients Wtih Glaucoma or Ocular Hypertension", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Ocular Hypertension" ], "interventions": [ { "name": "bimatoprost/timolol fixed combination", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Allergan", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 541, "start_date": "2001-08", "completion_date": "2003-08", "has_results": false, "last_update_posted_date": "2011-05-30", "last_synced_at": "2026-10-01T05:09:14.807Z", "location_count": 1, "location_summary": "Ogden, Utah", "locations": [ { "city": "Ogden", "state": "Utah" } ], "official_url": "https://clinicaltrials.gov/study/NCT00332072" }, { "nct_id": "NCT01145898", "title": "Trusopt and Cosopt; Ocular Perfusion Pressure and Blood Flow: New Long-term Prospective Data", "overall_status": "COMPLETED", "study_type": "OBSERVATIONAL", "phases": [], "conditions": [ "Glaucoma" ], "interventions": [ { "name": "(Cosopt®, prostaglandin)", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Indiana University", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "30 Years", "maximum_age": null, "sex": "ALL", "summary": "30 Years and older" }, "enrollment_count": 56, "start_date": "2010-06", "completion_date": "2012-10", "has_results": true, "last_update_posted_date": "2014-01-22", "last_synced_at": "2026-10-01T05:09:14.807Z", "location_count": 1, "location_summary": "Indianapolis, Indiana", "locations": [ { "city": "Indianapolis", "state": "Indiana" } ], "official_url": "https://clinicaltrials.gov/study/NCT01145898" }, { "nct_id": "NCT05913232", "title": "Study of Safety and Efficacy of H-1337 in Subjects With Primary Open Angle Glaucoma or Ocular Hypertension", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2" ], "conditions": [ "Glaucoma Open-Angle Primary", "Ocular Hypertension" ], "interventions": [ { "name": "H-1337 0.6%", "type": "DRUG" }, { "name": "H-1337 1.0%", "type": "DRUG" }, { "name": "H-1337 Placebo", "type": "DRUG" }, { "name": "Timolol 0.5%", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "D. Western Therapeutics Institute, Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 201, "start_date": "2023-08-28", "completion_date": "2024-08-29", "has_results": true, "last_update_posted_date": "2025-08-27", "last_synced_at": "2026-10-01T05:09:14.807Z", "location_count": 9, "location_summary": "Glendale, California • Colorado Springs, Colorado • Lakeland, Florida + 6 more", "locations": [ { "city": "Glendale", "state": "California" }, { "city": "Colorado Springs", "state": "Colorado" }, { "city": "Lakeland", "state": "Florida" }, { "city": "Largo", "state": "Florida" }, { "city": "Albany", "state": "Georgia" } ], "official_url": "https://clinicaltrials.gov/study/NCT05913232" }, { "nct_id": "NCT07218796", "title": "Evaluation of the Safety and Efficacy of the Bimatoprost Implant System Used in Combination With the SpyGlass IOL Compared to Timolol Ophthalmic Solution (Rhone)", "overall_status": "RECRUITING", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Cataract", "Glaucoma", "Ocular Hypertension" ], "interventions": [ { "name": "Bimatoprost Implant System", "type": "DRUG" }, { "name": "SpyGlass IOL", "type": "DEVICE" }, { "name": "Timolol Maleate Ophthalmic Solution, 0.5%", "type": "DRUG" }, { "name": "Commercial IOL", "type": "DEVICE" } ], "intervention_types": [ "DRUG", "DEVICE" ], "sponsor": "SpyGlass Pharma, Inc.", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "22 Years", "maximum_age": null, "sex": "ALL", "summary": "22 Years and older" }, "enrollment_count": 400, "start_date": "2025-10-28", "completion_date": "2031-05-31", "has_results": false, "last_update_posted_date": "2025-10-20", "last_synced_at": "2026-10-01T05:09:14.807Z", "location_count": 1, "location_summary": "San Antonio, Texas", "locations": [ { "city": "San Antonio", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT07218796" }, { "nct_id": "NCT03579160", "title": "Efficacy and Safety of 0.25% Timolol Gel in Enhancing Full Thickness Skin Grafts Healing and Cosmetic Outcomes", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE2", "PHASE3" ], "conditions": [ "Wound of Skin", "Wound Heal", "Surgical Wound", "Full Thickness Skin Graft Healing" ], "interventions": [ { "name": "0.25% timolol gel with full-thickness skin grafts", "type": "DRUG" }, { "name": "Vaseline dressing", "type": "OTHER" } ], "intervention_types": [ "DRUG", "OTHER" ], "sponsor": "Brigham and Women's Hospital", "sponsor_class": "OTHER", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 10, "start_date": "2019-01-02", "completion_date": "2022-01-10", "has_results": true, "last_update_posted_date": "2026-06-09", "last_synced_at": "2026-10-01T05:09:14.807Z", "location_count": 1, "location_summary": "Boston, Massachusetts", "locations": [ { "city": "Boston", "state": "Massachusetts" } ], "official_url": "https://clinicaltrials.gov/study/NCT03579160" }, { "nct_id": "NCT01177098", "title": "Safety and Efficacy of a New Formulation of Bimatoprost/Timolol Ophthalmic Solution Compared With Bimatoprost/Timolol Ophthalmic Solution in Patients With Glaucoma or Ocular Hypertension", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Glaucoma", "Ocular Hypertension" ], "interventions": [ { "name": "bimatoprost /timolol formulation A fixed combination ophthalmic solution", "type": "DRUG" }, { "name": "bimatoprost/timolol fixed combination ophthalmic solution", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Allergan", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 561, "start_date": "2010-10", "completion_date": "2012-02", "has_results": true, "last_update_posted_date": "2013-03-29", "last_synced_at": "2026-10-01T05:09:14.807Z", "location_count": 1, "location_summary": "Artesia, California", "locations": [ { "city": "Artesia", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT01177098" } ] }