{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Tissue+expander",
    "query": {
      "intervention": "Tissue expander"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 66,
    "total_pages": 7,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Tissue+expander&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-02T06:36:52.049Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT00588419",
      "title": "Quantification of Breast Sensation Following Postmastectomy Breast Reconstruction",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Breast Cancer",
        "Cancer"
      ],
      "interventions": [
        {
          "name": "breast exam and questionaire",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Memorial Sloan Kettering Cancer Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "21 Years and older · Female only"
      },
      "enrollment_count": 153,
      "start_date": "2006-06",
      "completion_date": "2021-04-07",
      "has_results": false,
      "last_update_posted_date": "2021-04-09",
      "last_synced_at": "2026-09-02T06:36:52.049Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00588419"
    },
    {
      "nct_id": "NCT05190978",
      "title": "Randomized Feasibility Trial for Mesh in Pre-Pectoral Reconstruction",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Breast Cancer",
        "Breast Implant; Complications, Infection or Inflammation"
      ],
      "interventions": [
        {
          "name": "Acellular Dermal Matrix",
          "type": "DEVICE"
        },
        {
          "name": "Reconstruction without ADM",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "DEVICE",
        "PROCEDURE"
      ],
      "sponsor": "University of California, Los Angeles",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "22 Years",
        "maximum_age": "75 Years",
        "sex": "FEMALE",
        "summary": "22 Years to 75 Years · Female only"
      },
      "enrollment_count": 120,
      "start_date": "2022-10-20",
      "completion_date": "2027-04-30",
      "has_results": false,
      "last_update_posted_date": "2026-05-05",
      "last_synced_at": "2026-09-02T06:36:52.049Z",
      "location_count": 1,
      "location_summary": "Los Angeles, California",
      "locations": [
        {
          "city": "Los Angeles",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05190978"
    },
    {
      "nct_id": "NCT01027637",
      "title": "Regenerative Tissue Matrix for Breast Reconstruction",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Breast Cancer"
      ],
      "interventions": [
        {
          "name": "5 mm vessel clips",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Henry Ford Health System",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "70 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 70 Years · Female only"
      },
      "enrollment_count": 33,
      "start_date": "2010-01",
      "completion_date": "2011-06",
      "has_results": false,
      "last_update_posted_date": "2013-09-06",
      "last_synced_at": "2026-09-02T06:36:52.049Z",
      "location_count": 1,
      "location_summary": "Detroit, Michigan",
      "locations": [
        {
          "city": "Detroit",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01027637"
    },
    {
      "nct_id": "NCT01286870",
      "title": "Becker Continued Access Study",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Breast Reconstruction"
      ],
      "interventions": [
        {
          "name": "Mentor Becker 25 Expander/Breast Implant",
          "type": "DEVICE"
        },
        {
          "name": "Mentor Becker 50 Expander/Breast Implant",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Mentor Worldwide, LLC",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "18 Years and older · Female only"
      },
      "enrollment_count": 11,
      "start_date": "2009-06-01",
      "completion_date": "2014-03-04",
      "has_results": true,
      "last_update_posted_date": "2019-03-06",
      "last_synced_at": "2026-09-02T06:36:52.049Z",
      "location_count": 1,
      "location_summary": "Santa Barbara, California",
      "locations": [
        {
          "city": "Santa Barbara",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01286870"
    },
    {
      "nct_id": "NCT05585710",
      "title": "Pulsed Lavage in Implant-Based Breast Reconstruction",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Breast Reconstruction"
      ],
      "interventions": [
        {
          "name": "Pulsed Lavage Washout",
          "type": "OTHER"
        },
        {
          "name": "Implant-based breast reconstruction",
          "type": "PROCEDURE"
        },
        {
          "name": "Bilateral or unilateral mastectomy",
          "type": "PROCEDURE"
        },
        {
          "name": "Tissue expander",
          "type": "DEVICE"
        },
        {
          "name": "Acellular dermal matrix",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER",
        "PROCEDURE",
        "DEVICE"
      ],
      "sponsor": "University of Alabama at Birmingham",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "75 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 75 Years · Female only"
      },
      "enrollment_count": 62,
      "start_date": "2024-03-01",
      "completion_date": "2027-08",
      "has_results": false,
      "last_update_posted_date": "2026-05-18",
      "last_synced_at": "2026-09-02T06:36:52.049Z",
      "location_count": 1,
      "location_summary": "Birmingham, Alabama",
      "locations": [
        {
          "city": "Birmingham",
          "state": "Alabama"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05585710"
    },
    {
      "nct_id": "NCT00616824",
      "title": "The Use of an Acellular Dermal Matrix in a Two-Staged Breast Reconstruction",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Mastectomy",
        "Postoperative Pain",
        "Complications"
      ],
      "interventions": [
        {
          "name": "Dermamatrix to cover lateral aspect of tissue expander",
          "type": "PROCEDURE"
        },
        {
          "name": "Serratus anterior to cover lateral aspect of tissue expander",
          "type": "PROCEDURE"
        }
      ],
      "intervention_types": [
        "PROCEDURE"
      ],
      "sponsor": "Vanderbilt University Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "18 Years and older · Female only"
      },
      "enrollment_count": 36,
      "start_date": "2007-09",
      "completion_date": "2010-03",
      "has_results": false,
      "last_update_posted_date": "2017-04-04",
      "last_synced_at": "2026-09-02T06:36:52.049Z",
      "location_count": 1,
      "location_summary": "Nashville, Tennessee",
      "locations": [
        {
          "city": "Nashville",
          "state": "Tennessee"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT00616824"
    },
    {
      "nct_id": "NCT03360214",
      "title": "PEMF and PEC Blocks in Mastectomy Reconstruction Patients",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Breast Cancer Female"
      ],
      "interventions": [
        {
          "name": "Bupivacaine Hydrochloride",
          "type": "DRUG"
        },
        {
          "name": "Placebo Drug",
          "type": "OTHER"
        },
        {
          "name": "Pulsed Electromagnetic Field (PEMF) Device",
          "type": "DEVICE"
        },
        {
          "name": "Placebo Device",
          "type": "OTHER"
        },
        {
          "name": "Ropivacaine Hydrochloride",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER",
        "DEVICE"
      ],
      "sponsor": "Columbia University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "18 Years and older · Female only"
      },
      "enrollment_count": 60,
      "start_date": "2017-07-05",
      "completion_date": "2022-03-07",
      "has_results": true,
      "last_update_posted_date": "2025-06-15",
      "last_synced_at": "2026-09-02T06:36:52.049Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03360214"
    },
    {
      "nct_id": "NCT02395614",
      "title": "Surgical Site Infection With 0.05% Chlorhexidine (CHG) Compared to Triple Antibiotic Irrigation",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Breast Cancer"
      ],
      "interventions": [
        {
          "name": "Chlorhexidine irrigation",
          "type": "DRUG"
        },
        {
          "name": "triple antibiotic irrigation",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Vanderbilt University Medical Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "81 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 81 Years · Female only"
      },
      "enrollment_count": 88,
      "start_date": "2015-12",
      "completion_date": "2020-12",
      "has_results": true,
      "last_update_posted_date": "2022-01-26",
      "last_synced_at": "2026-09-02T06:36:52.049Z",
      "location_count": 1,
      "location_summary": "Nashville, Tennessee",
      "locations": [
        {
          "city": "Nashville",
          "state": "Tennessee"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02395614"
    },
    {
      "nct_id": "NCT01082003",
      "title": "Prevention of Capsular Contracture Using Trental and Vitamin E",
      "overall_status": "UNKNOWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Capsular Contractures"
      ],
      "interventions": [
        {
          "name": "Trental",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Legacy Health System",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "18 Years and older · Female only"
      },
      "enrollment_count": 30,
      "start_date": "2009-10",
      "completion_date": "2014-06",
      "has_results": false,
      "last_update_posted_date": "2013-08-28",
      "last_synced_at": "2026-09-02T06:36:52.049Z",
      "location_count": 1,
      "location_summary": "Portland, Oregon",
      "locations": [
        {
          "city": "Portland",
          "state": "Oregon"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01082003"
    },
    {
      "nct_id": "NCT07220967",
      "title": "A Study of Antibiotic Delivery to Prevent Infection After Breast Tissue Expander Placement",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Breast Cancer"
      ],
      "interventions": [
        {
          "name": "Tissue Expander (TE)",
          "type": "PROCEDURE"
        },
        {
          "name": "Vancomycin and Gentamicin",
          "type": "DRUG"
        },
        {
          "name": "Stimulan Rapid Cure",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "PROCEDURE",
        "DRUG",
        "DEVICE"
      ],
      "sponsor": "Memorial Sloan Kettering Cancer Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "FEMALE",
        "summary": "18 Years and older · Female only"
      },
      "enrollment_count": 392,
      "start_date": "2025-10-21",
      "completion_date": "2027-10",
      "has_results": false,
      "last_update_posted_date": "2026-07-10",
      "last_synced_at": "2026-09-02T06:36:52.049Z",
      "location_count": 7,
      "location_summary": "Basking Ridge, New Jersey • Middletown, New Jersey • Montvale, New Jersey + 4 more",
      "locations": [
        {
          "city": "Basking Ridge",
          "state": "New Jersey"
        },
        {
          "city": "Middletown",
          "state": "New Jersey"
        },
        {
          "city": "Montvale",
          "state": "New Jersey"
        },
        {
          "city": "Commack",
          "state": "New York"
        },
        {
          "city": "Harrison",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07220967"
    }
  ]
}