{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Tobacco+Cigarette",
    "query": {
      "intervention": "Tobacco Cigarette"
    },
    "page_size": 10
  },
  "pagination": {
    "page": 1,
    "page_size": 10,
    "total_count": 532,
    "total_pages": 54,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Tobacco+Cigarette&page=2&page_size=10",
    "previous_page_url": null
  },
  "source": "remote",
  "last_synced_at": "2026-09-23T08:34:03.173Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT01921439",
      "title": "OCAST Cessation Study",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Tobacco Smoking Behavior",
        "Cigarette Smoking Behavior",
        "Second Hand Tobacco Smoke",
        "Tobacco Use Cessation"
      ],
      "interventions": [
        {
          "name": "Personalized Feedback",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Oklahoma",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 152,
      "start_date": "2013-07",
      "completion_date": "2016-12",
      "has_results": false,
      "last_update_posted_date": "2017-04-11",
      "last_synced_at": "2026-09-23T08:34:03.173Z",
      "location_count": 1,
      "location_summary": "Oklahoma City, Oklahoma",
      "locations": [
        {
          "city": "Oklahoma City",
          "state": "Oklahoma"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01921439"
    },
    {
      "nct_id": "NCT01721473",
      "title": "Brain Nicotine Receptor Density in Veteran Smokers",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Positron Emission Tomography"
      ],
      "interventions": [
        {
          "name": "positron emission tomography scan",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "VA Office of Research and Development",
      "sponsor_class": "FED",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "18 Years to 65 Years"
      },
      "enrollment_count": 184,
      "start_date": "2012-01-01",
      "completion_date": "2016-06-30",
      "has_results": true,
      "last_update_posted_date": "2019-10-07",
      "last_synced_at": "2026-09-23T08:34:03.173Z",
      "location_count": 2,
      "location_summary": "San Diego, California • West Los Angeles, California",
      "locations": [
        {
          "city": "San Diego",
          "state": "California"
        },
        {
          "city": "West Los Angeles",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01721473"
    },
    {
      "nct_id": "NCT01664741",
      "title": "Nicotine Dependence, Withdrawal and Replacement Therapy Assessed by PET Imaging",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE4"
      ],
      "conditions": [
        "Nicotine Dependence"
      ],
      "interventions": [
        {
          "name": "Nicotine patch - transdermal",
          "type": "DRUG"
        },
        {
          "name": "placebo",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Johns Hopkins University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "60 Years",
        "sex": "ALL",
        "summary": "21 Years to 60 Years"
      },
      "enrollment_count": 127,
      "start_date": "2012-04",
      "completion_date": "2018-12",
      "has_results": true,
      "last_update_posted_date": "2019-05-09",
      "last_synced_at": "2026-09-23T08:34:03.173Z",
      "location_count": 1,
      "location_summary": "Baltimore, Maryland",
      "locations": [
        {
          "city": "Baltimore",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01664741"
    },
    {
      "nct_id": "NCT02328794",
      "title": "Randomized Clinical Trial to Reduce Harm From Tobacco",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Smoking Cessation"
      ],
      "interventions": [
        {
          "name": "E-cigarette free access",
          "type": "BEHAVIORAL"
        },
        {
          "name": "E-cigarette/NRT/Zyban/Chantix Choice",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Outcome Incentive arm",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Loss framing incentive arm",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Control",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Pennsylvania",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "99 Years",
        "sex": "ALL",
        "summary": "18 Years to 99 Years"
      },
      "enrollment_count": 6006,
      "start_date": "2015-01-01",
      "completion_date": "2017-04-20",
      "has_results": false,
      "last_update_posted_date": "2017-05-02",
      "last_synced_at": "2026-09-23T08:34:03.173Z",
      "location_count": 1,
      "location_summary": "Philadelphia, Pennsylvania",
      "locations": [
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02328794"
    },
    {
      "nct_id": "NCT02061917",
      "title": "Switching From Usual Brand Cigarettes to a Tobacco-heating Cigarette or Snus",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Cigarette Smoking"
      ],
      "interventions": [
        {
          "name": "Tobacco-Heating Cigarette",
          "type": "OTHER"
        },
        {
          "name": "Snus (Smokeless Tobacco)",
          "type": "OTHER"
        },
        {
          "name": "Tobacco-Burning Cigarette",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "R.J. Reynolds Tobacco Company",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "28 Years",
        "maximum_age": "55 Years",
        "sex": "ALL",
        "summary": "28 Years to 55 Years"
      },
      "enrollment_count": 163,
      "start_date": "2007-02",
      "completion_date": "2009-11",
      "has_results": false,
      "last_update_posted_date": "2016-02-17",
      "last_synced_at": "2026-09-23T08:34:03.173Z",
      "location_count": 5,
      "location_summary": "Daytona Beach, Florida • Boise, Idaho • Portland, Oregon + 2 more",
      "locations": [
        {
          "city": "Daytona Beach",
          "state": "Florida"
        },
        {
          "city": "Boise",
          "state": "Idaho"
        },
        {
          "city": "Portland",
          "state": "Oregon"
        },
        {
          "city": "Austin",
          "state": "Texas"
        },
        {
          "city": "Dallas",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02061917"
    },
    {
      "nct_id": "NCT02942212",
      "title": "Health Literacy and Smoking Cessation in Low-SES Diverse Smokers - Project HALT II",
      "overall_status": "WITHDRAWN",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "EARLY_PHASE1"
      ],
      "conditions": [
        "Smoking Cessation"
      ],
      "interventions": [
        {
          "name": "Questionnaire",
          "type": "BEHAVIORAL"
        },
        {
          "name": "In-Depth Interviews",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Breath Test",
          "type": "OTHER"
        },
        {
          "name": "Nicotine Patches",
          "type": "DRUG"
        },
        {
          "name": "Advice plus Phone Counseling",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Advice plus Counseling Sessions",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Self Assessment Questionnaires",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL",
        "OTHER",
        "DRUG"
      ],
      "sponsor": "M.D. Anderson Cancer Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "25 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "25 Years to 65 Years"
      },
      "enrollment_count": 0,
      "start_date": "2018-12-14",
      "completion_date": "2018-12-14",
      "has_results": false,
      "last_update_posted_date": "2019-05-01",
      "last_synced_at": "2026-09-23T08:34:03.173Z",
      "location_count": 1,
      "location_summary": "Houston, Texas",
      "locations": [
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02942212"
    },
    {
      "nct_id": "NCT01625637",
      "title": "Tobacco Approach Avoidance Training for Adolescent Smokers-2",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE2"
      ],
      "conditions": [
        "Tobacco Use Disorder"
      ],
      "interventions": [
        {
          "name": "AAT-experiment",
          "type": "BEHAVIORAL"
        },
        {
          "name": "AAT-placebo",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Yale University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "13 Years",
        "maximum_age": "18 Years",
        "sex": "ALL",
        "summary": "13 Years to 18 Years"
      },
      "enrollment_count": 66,
      "start_date": "2012-05",
      "completion_date": "2013-08",
      "has_results": false,
      "last_update_posted_date": "2014-01-20",
      "last_synced_at": "2026-09-23T08:34:03.173Z",
      "location_count": 1,
      "location_summary": "New Haven, Connecticut",
      "locations": [
        {
          "city": "New Haven",
          "state": "Connecticut"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01625637"
    },
    {
      "nct_id": "NCT05458895",
      "title": "Evaluating E-Cigarette Nicotine Form, Concentration, and Flavors Among Youth",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "E-cigarette Use"
      ],
      "interventions": [
        {
          "name": "ECIG lab session 1",
          "type": "OTHER"
        },
        {
          "name": "ECIG lab session 2",
          "type": "OTHER"
        },
        {
          "name": "ECIG lab session 3",
          "type": "OTHER"
        },
        {
          "name": "ECIG lab session 4",
          "type": "OTHER"
        },
        {
          "name": "ECIG lab session 5",
          "type": "OTHER"
        },
        {
          "name": "ECIG lab session 6",
          "type": "OTHER"
        },
        {
          "name": "ECIG lab session 7",
          "type": "OTHER"
        },
        {
          "name": "ECIG lab session 8",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Ohio State University Comprehensive Cancer Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "25 Years",
        "sex": "ALL",
        "summary": "21 Years to 25 Years"
      },
      "enrollment_count": 88,
      "start_date": "2021-12-02",
      "completion_date": "2023-08-07",
      "has_results": true,
      "last_update_posted_date": "2024-11-22",
      "last_synced_at": "2026-09-23T08:34:03.173Z",
      "location_count": 1,
      "location_summary": "Columbus, Ohio",
      "locations": [
        {
          "city": "Columbus",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05458895"
    },
    {
      "nct_id": "NCT06534905",
      "title": "E-cigarette Switching Older Adults",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Tobacco Use",
        "Opioid Use Disorder",
        "Tobacco-Related Disorders"
      ],
      "interventions": [
        {
          "name": "E-cigarette",
          "type": "OTHER"
        },
        {
          "name": "Control/Standard Advice",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "OTHER",
        "BEHAVIORAL"
      ],
      "sponsor": "University of Maryland, Baltimore",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "50 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "50 Years and older"
      },
      "enrollment_count": 36,
      "start_date": "2024-11-25",
      "completion_date": "2025-10-31",
      "has_results": false,
      "last_update_posted_date": "2026-07-10",
      "last_synced_at": "2026-09-23T08:34:03.173Z",
      "location_count": 1,
      "location_summary": "Baltimore, Maryland",
      "locations": [
        {
          "city": "Baltimore",
          "state": "Maryland"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06534905"
    },
    {
      "nct_id": "NCT03559751",
      "title": "Evaluation of the Abuse Liability of Very Low Nicotine (VLN) Cigarettes",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1"
      ],
      "conditions": [
        "Tobacco Use"
      ],
      "interventions": [
        {
          "name": "VLN cigarettes (A)",
          "type": "OTHER"
        },
        {
          "name": "Usual Brand Cigarettes (B)",
          "type": "OTHER"
        },
        {
          "name": "Nicotine gum (C)",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "OTHER",
        "DRUG"
      ],
      "sponsor": "22nd Century Group, Inc.",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "22 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "22 Years to 65 Years"
      },
      "enrollment_count": 66,
      "start_date": "2018-04-13",
      "completion_date": "2018-09-06",
      "has_results": false,
      "last_update_posted_date": "2020-03-26",
      "last_synced_at": "2026-09-23T08:34:03.173Z",
      "location_count": 1,
      "location_summary": "Overland Park, Kansas",
      "locations": [
        {
          "city": "Overland Park",
          "state": "Kansas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03559751"
    }
  ]
}