{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Tobacco+Use+Disorder&page=2",
    "query": {
      "intervention": "Tobacco Use Disorder",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 280,
    "total_pages": 28,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Tobacco+Use+Disorder&page=3&page_size=10",
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Tobacco+Use+Disorder&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-09-30T17:36:14.754Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT03904186",
      "title": "Effectiveness of an Integrated Treatment to Address Smoking Cessation and Anxiety/ Depression in People Living With HIV",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Human Immunodeficiency Virus",
        "Smoking Cessation",
        "Smoking, Cigarette",
        "Smoking",
        "Anxiety",
        "Depression",
        "Nicotine Dependence"
      ],
      "interventions": [
        {
          "name": "QUIT",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Time-Matched Control (TM)",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Massachusetts General Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "79 Years",
        "sex": "ALL",
        "summary": "18 Years to 79 Years"
      },
      "enrollment_count": 131,
      "start_date": "2019-12-19",
      "completion_date": "2025-02-28",
      "has_results": false,
      "last_update_posted_date": "2026-02-09",
      "last_synced_at": "2026-09-30T17:36:14.754Z",
      "location_count": 3,
      "location_summary": "Boston, Massachusetts • Houston, Texas",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "Boston",
          "state": "Massachusetts"
        },
        {
          "city": "Houston",
          "state": "Texas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03904186"
    },
    {
      "nct_id": "NCT07594717",
      "title": "Effects of E-Cigarette Flavors on Adult E-Cigarette Users With Opioid Use Disorder",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Nicotine Use Disoder",
        "Opioid Use Disorder"
      ],
      "interventions": [
        {
          "name": "Sweet-cooling",
          "type": "DRUG"
        },
        {
          "name": "Sweet non-cooling EC flavor",
          "type": "DRUG"
        },
        {
          "name": "Tobacco flavor EC",
          "type": "DRUG"
        }
      ],
      "intervention_types": [
        "DRUG"
      ],
      "sponsor": "Prisma Health-Upstate",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "21 Years and older"
      },
      "enrollment_count": 70,
      "start_date": "2025-11-12",
      "completion_date": "2026-04-28",
      "has_results": false,
      "last_update_posted_date": "2026-08-03",
      "last_synced_at": "2026-09-30T17:36:14.754Z",
      "location_count": 1,
      "location_summary": "Greenville, South Carolina",
      "locations": [
        {
          "city": "Greenville",
          "state": "South Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07594717"
    },
    {
      "nct_id": "NCT05894954",
      "title": "Precision Medicine Approach for Early Dementia & Mild Cognitive Impairment",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Mild Cognitive Impairment",
        "Dementia, Mild"
      ],
      "interventions": [
        {
          "name": "Precision Medicine Approach",
          "type": "DIETARY_SUPPLEMENT"
        },
        {
          "name": "Hormones and Medications tailored to lab tests, combined with devices that support stress management and brain exercises",
          "type": "COMBINATION_PRODUCT"
        },
        {
          "name": "Standard-of-Care",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Lifestyle including diet, exercise, stress management",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "DIETARY_SUPPLEMENT",
        "COMBINATION_PRODUCT",
        "BEHAVIORAL"
      ],
      "sponsor": "Alzheimer's Prevention and Reversal Project, Inc.",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "45 Years",
        "maximum_age": "76 Years",
        "sex": "ALL",
        "summary": "45 Years to 76 Years"
      },
      "enrollment_count": 73,
      "start_date": "2023-07-31",
      "completion_date": "2026-02-09",
      "has_results": false,
      "last_update_posted_date": "2026-02-18",
      "last_synced_at": "2026-09-30T17:36:14.754Z",
      "location_count": 6,
      "location_summary": "Folsom, California • San Rafael, California • Walnut Creek, California + 3 more",
      "locations": [
        {
          "city": "Folsom",
          "state": "California"
        },
        {
          "city": "San Rafael",
          "state": "California"
        },
        {
          "city": "Walnut Creek",
          "state": "California"
        },
        {
          "city": "Hollywood",
          "state": "Florida"
        },
        {
          "city": "Rocky River",
          "state": "Ohio"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT05894954"
    },
    {
      "nct_id": "NCT07202039",
      "title": "Electronic Cigarettes as a Harm Reduction Strategy Among People With Opioid Use Disorder on Buprenorphine",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Tobacco-flavored EC",
        "Sweet-Cooling EC",
        "Sweet Non-cooling EC"
      ],
      "interventions": [
        {
          "name": "Brief individual counseling sessions",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Prisma Health-Upstate",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "21 Years and older"
      },
      "enrollment_count": 90,
      "start_date": "2026-04-29",
      "completion_date": "2029-06-29",
      "has_results": false,
      "last_update_posted_date": "2026-05-12",
      "last_synced_at": "2026-09-30T17:36:14.754Z",
      "location_count": 1,
      "location_summary": "Greenville, South Carolina",
      "locations": [
        {
          "city": "Greenville",
          "state": "South Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07202039"
    },
    {
      "nct_id": "NCT06747871",
      "title": "Opioids, Low Nicotine Cigarettes, and Chronic Pain",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Chronic Pain",
        "Tobacco Use",
        "Opioid Substitution Treatment"
      ],
      "interventions": [
        {
          "name": "Very Low Nicotine Cigarettes (VLNC)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Normal Nicotine Cigarettes (NNC)",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Duke University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "21 Years and older"
      },
      "enrollment_count": 60,
      "start_date": "2025-04-15",
      "completion_date": "2027-07-30",
      "has_results": false,
      "last_update_posted_date": "2026-01-09",
      "last_synced_at": "2026-09-30T17:36:14.754Z",
      "location_count": 1,
      "location_summary": "Durham, North Carolina",
      "locations": [
        {
          "city": "Durham",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06747871"
    },
    {
      "nct_id": "NCT06609902",
      "title": "A Future Thinking Intervention for Comorbid Tobacco Use Disorder and Bipolar Disorder",
      "overall_status": "ACTIVE_NOT_RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Bipolar Disorder",
        "Tobacco Use Disorder"
      ],
      "interventions": [
        {
          "name": "Future Self-BD",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Daily Check-Ins",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Massachusetts General Hospital",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 70,
      "start_date": "2024-12-06",
      "completion_date": "2028-04-30",
      "has_results": false,
      "last_update_posted_date": "2026-04-17",
      "last_synced_at": "2026-09-30T17:36:14.754Z",
      "location_count": 1,
      "location_summary": "Boston, Massachusetts",
      "locations": [
        {
          "city": "Boston",
          "state": "Massachusetts"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06609902"
    },
    {
      "nct_id": "NCT06678672",
      "title": "Contingency Management for Veteran Smokers Undergoing Major Elective Surgery",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Tobacco Use Disorder",
        "Substance Use Disorder (SUD)"
      ],
      "interventions": [
        {
          "name": "Contingency Management (CM)",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Treatment as Usual (TAU)",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of California, San Francisco",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 36,
      "start_date": "2025-08-01",
      "completion_date": "2027-07-01",
      "has_results": false,
      "last_update_posted_date": "2026-08-11",
      "last_synced_at": "2026-09-30T17:36:14.754Z",
      "location_count": 1,
      "location_summary": "San Francisco, California",
      "locations": [
        {
          "city": "San Francisco",
          "state": "California"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06678672"
    },
    {
      "nct_id": "NCT02358330",
      "title": "Project 1: Evaluating EHR-Based Health System Modifications for the Chronic Care of Smoking",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Smoking",
        "Nicotine Dependence",
        "Electronic Health Records",
        "Translational Research"
      ],
      "interventions": [
        {
          "name": "EHR Enhanced Clinic Intervention",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "University of Wisconsin, Madison",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": null,
        "maximum_age": null,
        "sex": "ALL",
        "summary": "Not listed"
      },
      "enrollment_count": 28095,
      "start_date": "2015-02",
      "completion_date": "2018-08-01",
      "has_results": false,
      "last_update_posted_date": "2020-05-13",
      "last_synced_at": "2026-09-30T17:36:14.754Z",
      "location_count": 1,
      "location_summary": "Madison, Wisconsin",
      "locations": [
        {
          "city": "Madison",
          "state": "Wisconsin"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02358330"
    },
    {
      "nct_id": "NCT07802262",
      "title": "Prenatal Exercise and Glucose Regulation",
      "overall_status": "RECRUITING",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Gestational Diabetes Mellitus",
        "Gestational Diabetes Mellitus in Pregnancy",
        "Insulin Resistance"
      ],
      "interventions": [
        {
          "name": "Acute exercises sessions with different exercise types and intensities",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Central Arkansas",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "35 Years",
        "sex": "FEMALE",
        "summary": "18 Years to 35 Years · Female only"
      },
      "enrollment_count": 23,
      "start_date": "2024-09-24",
      "completion_date": "2028-01-31",
      "has_results": false,
      "last_update_posted_date": "2026-09-03",
      "last_synced_at": "2026-09-30T17:36:14.754Z",
      "location_count": 1,
      "location_summary": "Conway, Arkansas",
      "locations": [
        {
          "city": "Conway",
          "state": "Arkansas"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07802262"
    },
    {
      "nct_id": "NCT01482923",
      "title": "Tobacco Assessment and Intervention With Low-Income Persons Living With HIV-AIDS (PLWHA) in Community-Based AIDS Service Organizations",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Tobacco Cessation",
        "HIV",
        "AIDS"
      ],
      "interventions": [
        {
          "name": "Treatment as usual",
          "type": "BEHAVIORAL"
        },
        {
          "name": "AIR (Aspirations, Inspiration, Respiration)",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Memorial Sloan Kettering Cancer Center",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 65,
      "start_date": "2011-11-22",
      "completion_date": "2019-10-21",
      "has_results": false,
      "last_update_posted_date": "2019-11-04",
      "last_synced_at": "2026-09-30T17:36:14.754Z",
      "location_count": 1,
      "location_summary": "New York, New York",
      "locations": [
        {
          "city": "New York",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT01482923"
    }
  ]
}