{
  "api_version": "1",
  "request": {
    "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Tobacco+and+non-tobacco+e-cigarettes&page=2",
    "query": {
      "intervention": "Tobacco and non-tobacco e-cigarettes",
      "page": 2
    },
    "page_size": 10
  },
  "pagination": {
    "page": 2,
    "page_size": 10,
    "total_count": 67,
    "total_pages": 7,
    "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Tobacco+and+non-tobacco+e-cigarettes&page=3&page_size=10",
    "previous_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Tobacco+and+non-tobacco+e-cigarettes&page=1&page_size=10"
  },
  "source": "remote",
  "last_synced_at": "2026-10-12T10:32:03.157Z",
  "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.",
  "notes": [
    "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.",
    "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.",
    "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees."
  ],
  "trials": [
    {
      "nct_id": "NCT06088862",
      "title": "Evaluate Harm Reduction Products as a Second Line Intervention for Adult Smokers Who Do Not Quit With NRT",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE3"
      ],
      "conditions": [
        "Smoking Cessation",
        "Harm Reduction"
      ],
      "interventions": [
        {
          "name": "Nicoderm",
          "type": "DRUG"
        },
        {
          "name": "Nicorette 4Mg Chewing Gum",
          "type": "DRUG"
        },
        {
          "name": "Nicorette Lozenge Product",
          "type": "DRUG"
        },
        {
          "name": "BIDI e-cigarette",
          "type": "OTHER"
        },
        {
          "name": "on!",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "DRUG",
        "OTHER"
      ],
      "sponsor": "Rose Research Center, LLC",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "22 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "22 Years to 65 Years"
      },
      "enrollment_count": 4,
      "start_date": "2023-12-27",
      "completion_date": "2024-04-30",
      "has_results": false,
      "last_update_posted_date": "2025-03-30",
      "last_synced_at": "2026-10-12T10:32:03.157Z",
      "location_count": 2,
      "location_summary": "Charlotte, North Carolina • Raleigh, North Carolina",
      "locations": [
        {
          "city": "Charlotte",
          "state": "North Carolina"
        },
        {
          "city": "Raleigh",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT06088862"
    },
    {
      "nct_id": "NCT02328794",
      "title": "Randomized Clinical Trial to Reduce Harm From Tobacco",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Smoking Cessation"
      ],
      "interventions": [
        {
          "name": "E-cigarette free access",
          "type": "BEHAVIORAL"
        },
        {
          "name": "E-cigarette/NRT/Zyban/Chantix Choice",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Outcome Incentive arm",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Loss framing incentive arm",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Control",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Pennsylvania",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": "99 Years",
        "sex": "ALL",
        "summary": "18 Years to 99 Years"
      },
      "enrollment_count": 6006,
      "start_date": "2015-01-01",
      "completion_date": "2017-04-20",
      "has_results": false,
      "last_update_posted_date": "2017-05-02",
      "last_synced_at": "2026-10-12T10:32:03.157Z",
      "location_count": 1,
      "location_summary": "Philadelphia, Pennsylvania",
      "locations": [
        {
          "city": "Philadelphia",
          "state": "Pennsylvania"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02328794"
    },
    {
      "nct_id": "NCT04009850",
      "title": "Impact of Cigarette and E-cigarette Flavors on Adult Smoking Behavior",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Tobacco Use"
      ],
      "interventions": [
        {
          "name": "Cigarette Brand Switching",
          "type": "OTHER"
        },
        {
          "name": "E-cigarette Flavor",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "Yale University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 3,
      "start_date": "2019-07-01",
      "completion_date": "2022-01-31",
      "has_results": true,
      "last_update_posted_date": "2024-03-08",
      "last_synced_at": "2026-10-12T10:32:03.157Z",
      "location_count": 1,
      "location_summary": "New Haven, Connecticut",
      "locations": [
        {
          "city": "New Haven",
          "state": "Connecticut"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04009850"
    },
    {
      "nct_id": "NCT03743532",
      "title": "E-Cigarettes and Financial Incentives to Promote Tobacco Harm Reduction Among Adults Accessing Shelter Services",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Cigarette Smoking"
      ],
      "interventions": [
        {
          "name": "E-cigarette Switching",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Financial Incentives",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "University of Oklahoma",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "100 Years",
        "sex": "ALL",
        "summary": "21 Years to 100 Years"
      },
      "enrollment_count": 60,
      "start_date": "2022-09-14",
      "completion_date": "2023-03-01",
      "has_results": true,
      "last_update_posted_date": "2025-02-21",
      "last_synced_at": "2026-10-12T10:32:03.157Z",
      "location_count": 1,
      "location_summary": "Oklahoma City, Oklahoma",
      "locations": [
        {
          "city": "Oklahoma City",
          "state": "Oklahoma"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03743532"
    },
    {
      "nct_id": "NCT03897530",
      "title": "Experimental Tobacco Marketplace in Regulating Flavored Tobacco Products in Menthol Cigarette Smokers",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Cigarette Smoking"
      ],
      "interventions": [
        {
          "name": "Smoking Cessation Intervention",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Functional Assessment",
          "type": "OTHER"
        },
        {
          "name": "Questionnaire Administration",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL",
        "OTHER"
      ],
      "sponsor": "Roswell Park Cancer Institute",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 103,
      "start_date": "2019-06-30",
      "completion_date": "2023-07-20",
      "has_results": false,
      "last_update_posted_date": "2024-04-03",
      "last_synced_at": "2026-10-12T10:32:03.157Z",
      "location_count": 1,
      "location_summary": "Buffalo, New York",
      "locations": [
        {
          "city": "Buffalo",
          "state": "New York"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03897530"
    },
    {
      "nct_id": "NCT07172438",
      "title": "A RCT to Determine the Effect of ENDS Flavor Availability on Abstinence Within Smokers",
      "overall_status": "TERMINATED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Smoking",
        "Tobacco"
      ],
      "interventions": [
        {
          "name": "P2611222",
          "type": "OTHER"
        },
        {
          "name": "P2615022",
          "type": "OTHER"
        },
        {
          "name": "P2615122",
          "type": "OTHER"
        },
        {
          "name": "P2613422",
          "type": "OTHER"
        }
      ],
      "intervention_types": [
        "OTHER"
      ],
      "sponsor": "RAI Services Company",
      "sponsor_class": "INDUSTRY",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "21 Years to 65 Years"
      },
      "enrollment_count": 668,
      "start_date": "2025-09-17",
      "completion_date": "2026-01-14",
      "has_results": false,
      "last_update_posted_date": "2026-02-27",
      "last_synced_at": "2026-10-12T10:32:03.157Z",
      "location_count": 27,
      "location_summary": "Chandler, Arizona • Fort Smith, Arkansas • Altamonte Springs, Florida + 21 more",
      "locations": [
        {
          "city": "Chandler",
          "state": "Arizona"
        },
        {
          "city": "Fort Smith",
          "state": "Arkansas"
        },
        {
          "city": "Altamonte Springs",
          "state": "Florida"
        },
        {
          "city": "Clearwater",
          "state": "Florida"
        },
        {
          "city": "Maitland",
          "state": "Florida"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07172438"
    },
    {
      "nct_id": "NCT07010601",
      "title": "Tobacco Product Susceptibility and Substitutability by Rurality and Alcohol Use",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "NA"
      ],
      "conditions": [
        "Alcohol Use",
        "E-cigarette Use",
        "Cigarette Use"
      ],
      "interventions": [
        {
          "name": "Experimental Tobacco Marketplace",
          "type": "BEHAVIORAL"
        },
        {
          "name": "Hypothetical Novel Nicotine Product Purchase Tasks",
          "type": "BEHAVIORAL"
        }
      ],
      "intervention_types": [
        "BEHAVIORAL"
      ],
      "sponsor": "Mark J Rzeszutek, PhD",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "21 Years and older"
      },
      "enrollment_count": 737,
      "start_date": "2025-08-18",
      "completion_date": "2025-08-20",
      "has_results": false,
      "last_update_posted_date": "2025-09-23",
      "last_synced_at": "2026-10-12T10:32:03.157Z",
      "location_count": 1,
      "location_summary": "Lexington, Kentucky",
      "locations": [
        {
          "city": "Lexington",
          "state": "Kentucky"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT07010601"
    },
    {
      "nct_id": "NCT03284632",
      "title": "e-Cigarette - DNA Adducts",
      "overall_status": "COMPLETED",
      "study_type": "OBSERVATIONAL",
      "phases": [],
      "conditions": [
        "Smoking",
        "Cigarette Smoking",
        "Electronic Cigarettes"
      ],
      "interventions": [],
      "intervention_types": [],
      "sponsor": "University of Minnesota",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "18 Years",
        "maximum_age": null,
        "sex": "ALL",
        "summary": "18 Years and older"
      },
      "enrollment_count": 217,
      "start_date": "2017-07-11",
      "completion_date": "2021-06-01",
      "has_results": false,
      "last_update_posted_date": "2022-11-09",
      "last_synced_at": "2026-10-12T10:32:03.157Z",
      "location_count": 1,
      "location_summary": "Minneapolis, Minnesota",
      "locations": [
        {
          "city": "Minneapolis",
          "state": "Minnesota"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT03284632"
    },
    {
      "nct_id": "NCT02590393",
      "title": "The Role of Nicotine and Non-Nicotine Alkaloids in E-Cigarette Use and Dependence",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "PHASE1",
        "PHASE2"
      ],
      "conditions": [
        "Nicotine Dependence"
      ],
      "interventions": [
        {
          "name": "E-cigarettes",
          "type": "COMBINATION_PRODUCT"
        }
      ],
      "intervention_types": [
        "COMBINATION_PRODUCT"
      ],
      "sponsor": "Duke University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": false,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "65 Years",
        "sex": "ALL",
        "summary": "21 Years to 65 Years"
      },
      "enrollment_count": 20,
      "start_date": "2021-05-21",
      "completion_date": "2022-01-13",
      "has_results": false,
      "last_update_posted_date": "2024-02-21",
      "last_synced_at": "2026-10-12T10:32:03.157Z",
      "location_count": 1,
      "location_summary": "Durham, North Carolina",
      "locations": [
        {
          "city": "Durham",
          "state": "North Carolina"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT02590393"
    },
    {
      "nct_id": "NCT04613609",
      "title": "Vaporized Nicotine and Autonomic Control",
      "overall_status": "COMPLETED",
      "study_type": "INTERVENTIONAL",
      "phases": [
        "EARLY_PHASE1"
      ],
      "conditions": [
        "Electronic Cigarette Use"
      ],
      "interventions": [
        {
          "name": "Electronic Cigarette containing nicotine",
          "type": "DEVICE"
        },
        {
          "name": "Electronic Cigarette without nicotine",
          "type": "DEVICE"
        }
      ],
      "intervention_types": [
        "DEVICE"
      ],
      "sponsor": "Michigan Technological University",
      "sponsor_class": "OTHER",
      "healthy_volunteers": true,
      "eligibility": {
        "minimum_age": "21 Years",
        "maximum_age": "40 Years",
        "sex": "ALL",
        "summary": "21 Years to 40 Years"
      },
      "enrollment_count": 16,
      "start_date": "2018-04-01",
      "completion_date": "2019-07-01",
      "has_results": false,
      "last_update_posted_date": "2020-11-03",
      "last_synced_at": "2026-10-12T10:32:03.157Z",
      "location_count": 1,
      "location_summary": "Houghton, Michigan",
      "locations": [
        {
          "city": "Houghton",
          "state": "Michigan"
        }
      ],
      "official_url": "https://clinicaltrials.gov/study/NCT04613609"
    }
  ]
}