{ "api_version": "1", "request": { "url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Tofacitinib+citrate", "query": { "intervention": "Tofacitinib citrate" }, "page_size": 10 }, "pagination": { "page": 1, "page_size": 10, "total_count": 130, "total_pages": 13, "next_page_url": "https://clinicaltrialsfind.com/api/v1/search.json?intervention=Tofacitinib+citrate&page=2&page_size=10", "previous_page_url": null }, "source": "remote", "last_synced_at": "2026-09-17T23:58:10.573Z", "attribution": "Data derived from public ClinicalTrials.gov records. The official record at https://clinicaltrials.gov/ remains the source of truth for current availability, contacts, and full study details.", "notes": [ "This endpoint exposes only public summary fields — no participant contact emails, phone numbers, or scraped investigator contact details.", "For contact information and full protocol detail, follow each trial's `official_url` to the ClinicalTrials.gov record.", "This API is a navigational aid. It does not provide medical advice, eligibility determinations, or compensation guarantees." ], "trials": [ { "nct_id": "NCT05080218", "title": "COVID-19 VaccinE Response in Rheumatology Patients", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Rheumatoid Arthritis", "Psoriatic Arthritis", "Spondylarthritis" ], "interventions": [ { "name": "Upadacitinib", "type": "DRUG" }, { "name": "Abatacept", "type": "DRUG" }, { "name": "Secukinumab", "type": "DRUG" }, { "name": "Tofacitinib", "type": "DRUG" }, { "name": "TNF Inhibitor", "type": "DRUG" }, { "name": "Canakinumab Injection", "type": "DRUG" }, { "name": "Baricitinib", "type": "DRUG" }, { "name": "Ixekizumab", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Jeffrey Curtis", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "85 Years", "sex": "ALL", "summary": "18 Years to 85 Years" }, "enrollment_count": 841, "start_date": "2021-11-15", "completion_date": "2024-05-28", "has_results": false, "last_update_posted_date": "2025-05-02", "last_synced_at": "2026-09-17T23:58:10.573Z", "location_count": 8, "location_summary": "Birmingham, Alabama • Hoover, Alabama • Phoenix, Arizona + 4 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "Hoover", "state": "Alabama" }, { "city": "Hoover", "state": "Alabama" }, { "city": "Phoenix", "state": "Arizona" }, { "city": "Beverly Hills", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT05080218" }, { "nct_id": "NCT01741493", "title": "A Study in Healthy Adults and Adult Subjects With Rheumatoid Arthritis to Evaluate the Safety, Tolerability and Pharmacokinetics After Multiple Doses of ABT-494", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Rheumatoid Arthritis" ], "interventions": [ { "name": "ABT-494", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" }, { "name": "Tofacitinib", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "AbbVie (prior sponsor, Abbott)", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "75 Years", "sex": "ALL", "summary": "18 Years to 75 Years" }, "enrollment_count": 67, "start_date": "2012-11", "completion_date": "2013-12", "has_results": false, "last_update_posted_date": "2017-11-20", "last_synced_at": "2026-09-17T23:58:10.573Z", "location_count": 5, "location_summary": "Miami, Florida • Cincinnati, Ohio • Duncansville, Pennsylvania + 2 more", "locations": [ { "city": "Miami", "state": "Florida" }, { "city": "Cincinnati", "state": "Ohio" }, { "city": "Duncansville", "state": "Pennsylvania" }, { "city": "Austin", "state": "Texas" }, { "city": "Orem", "state": "Utah" } ], "official_url": "https://clinicaltrials.gov/study/NCT01741493" }, { "nct_id": "NCT01877668", "title": "Efficacy And Safety Of Tofacitinib In Psoriatic Arthritis: Comparator Study", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Psoriatic Arthritis" ], "interventions": [ { "name": "Tofacitinib 5 mg BID", "type": "DRUG" }, { "name": "Tofacitinib 10 mg BID", "type": "DRUG" }, { "name": "Adalimumab", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Pfizer", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 422, "start_date": "2014-01-20", "completion_date": "2015-12-18", "has_results": true, "last_update_posted_date": "2017-07-06", "last_synced_at": "2026-09-17T23:58:10.573Z", "location_count": 24, "location_summary": "Birmingham, Alabama • Huntsville, Alabama • Glendale, Arizona + 17 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "Huntsville", "state": "Alabama" }, { "city": "Glendale", "state": "Arizona" }, { "city": "Covina", "state": "California" }, { "city": "Palm Desert", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT01877668" }, { "nct_id": "NCT01745055", "title": "Co-Administration Of Methotrexate And CP-690,550", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Rheumatoid Arthritis" ], "interventions": [ { "name": "CP-690,550 (tofacitinib)", "type": "DRUG" }, { "name": "Methotrexate (MTX)", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Pfizer", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "70 Years", "sex": "ALL", "summary": "18 Years to 70 Years" }, "enrollment_count": 12, "start_date": "2005-04", "completion_date": "2006-06", "has_results": true, "last_update_posted_date": "2013-02-04", "last_synced_at": "2026-09-17T23:58:10.573Z", "location_count": 4, "location_summary": "Daytona Beach, Florida • Fort Lauderdale, Florida • Miramar, Florida + 1 more", "locations": [ { "city": "Daytona Beach", "state": "Florida" }, { "city": "Fort Lauderdale", "state": "Florida" }, { "city": "Miramar", "state": "Florida" }, { "city": "Dallas", "state": "Texas" } ], "official_url": "https://clinicaltrials.gov/study/NCT01745055" }, { "nct_id": "NCT03159936", "title": "Oral Tofacitinib in Adult Subjects With Discoid Lupus Erythematosus (DLE) and Systemic Lupus Erythematosus (SLE)", "overall_status": "TERMINATED", "study_type": "INTERVENTIONAL", "phases": [ "EARLY_PHASE1" ], "conditions": [ "Discoid Lupus Erythematosus", "Systemic Lupus Erythematosus" ], "interventions": [ { "name": "Tofacitinib citrate", "type": "BIOLOGICAL" } ], "intervention_types": [ "BIOLOGICAL" ], "sponsor": "Tufts Medical Center", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "18 Years to 65 Years" }, "enrollment_count": 5, "start_date": "2017-04-03", "completion_date": "2020-06-10", "has_results": false, "last_update_posted_date": "2022-01-21", "last_synced_at": "2026-09-17T23:58:10.573Z", "location_count": 1, "location_summary": "Boston, Massachusetts", "locations": [ { "city": "Boston", "state": "Massachusetts" } ], "official_url": "https://clinicaltrials.gov/study/NCT03159936" }, { "nct_id": "NCT02084875", "title": "A Study To Evaluate The Effect Of Food On The Behavior Of Tofacitinib Modified Release 11 Milligram Tablets In Healthy Western And Japanese Volunteers", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Healthy" ], "interventions": [ { "name": "tofacitinib modified-release (MR) formulation", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Pfizer", "sponsor_class": "INDUSTRY", "healthy_volunteers": true, "eligibility": { "minimum_age": "18 Years", "maximum_age": "55 Years", "sex": "ALL", "summary": "18 Years to 55 Years" }, "enrollment_count": 24, "start_date": "2014-04-11", "completion_date": "2014-05-25", "has_results": false, "last_update_posted_date": "2018-11-30", "last_synced_at": "2026-09-17T23:58:10.573Z", "location_count": 1, "location_summary": "Glendale, California", "locations": [ { "city": "Glendale", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT02084875" }, { "nct_id": "NCT00814307", "title": "A Phase 3 Study Comparing 2 Doses of CP-690,550 vs. Placebo for Treatment of Rheumatoid Arthritis", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE3" ], "conditions": [ "Arthritis, Rheumatoid" ], "interventions": [ { "name": "CP-690,550", "type": "DRUG" }, { "name": "Placebo", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "Pfizer", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 611, "start_date": "2009-02", "completion_date": "2010-06", "has_results": true, "last_update_posted_date": "2013-01-18", "last_synced_at": "2026-09-17T23:58:10.573Z", "location_count": 31, "location_summary": "Gilbert, Arizona • Tucson, Arizona • Hot Springs, Arkansas + 27 more", "locations": [ { "city": "Gilbert", "state": "Arizona" }, { "city": "Tucson", "state": "Arizona" }, { "city": "Hot Springs", "state": "Arkansas" }, { "city": "Jacksonville", "state": "Florida" }, { "city": "Sarasota", "state": "Florida" } ], "official_url": "https://clinicaltrials.gov/study/NCT00814307" }, { "nct_id": "NCT02321930", "title": "Musculoskeletal Ultrasound Assessment of Therapeutic Response of Tofacitinib in Rheumatoid Arthritis Patients", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Rheumatoid Arthritis" ], "interventions": [ { "name": "tofacitinib 5mg po bid", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "University of California, Los Angeles", "sponsor_class": "OTHER", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": null, "sex": "ALL", "summary": "18 Years and older" }, "enrollment_count": 37, "start_date": "2016-02-16", "completion_date": "2017-09-29", "has_results": true, "last_update_posted_date": "2019-03-19", "last_synced_at": "2026-09-17T23:58:10.573Z", "location_count": 1, "location_summary": "Los Angeles, California", "locations": [ { "city": "Los Angeles", "state": "California" } ], "official_url": "https://clinicaltrials.gov/study/NCT02321930" }, { "nct_id": "NCT02092467", "title": "Safety Study Of Tofacitinib Versus Tumor Necrosis Factor (TNF) Inhibitor In Subjects With Rheumatoid Arthritis", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE4" ], "conditions": [ "Arthritis, Rheumatoid" ], "interventions": [ { "name": "tofacitinib", "type": "DRUG" }, { "name": "adalimumab", "type": "BIOLOGICAL" }, { "name": "etanercept", "type": "BIOLOGICAL" } ], "intervention_types": [ "DRUG", "BIOLOGICAL" ], "sponsor": "Pfizer", "sponsor_class": "INDUSTRY", "healthy_volunteers": false, "eligibility": { "minimum_age": "50 Years", "maximum_age": null, "sex": "ALL", "summary": "50 Years and older" }, "enrollment_count": 4372, "start_date": "2014-03-14", "completion_date": "2020-07-22", "has_results": true, "last_update_posted_date": "2021-08-17", "last_synced_at": "2026-09-17T23:58:10.573Z", "location_count": 142, "location_summary": "Birmingham, Alabama • Huntsville, Alabama • Tuscaloosa, Alabama + 110 more", "locations": [ { "city": "Birmingham", "state": "Alabama" }, { "city": "Huntsville", "state": "Alabama" }, { "city": "Tuscaloosa", "state": "Alabama" }, { "city": "Tucson", "state": "Arizona" }, { "city": "Tucson", "state": "Arizona" } ], "official_url": "https://clinicaltrials.gov/study/NCT02092467" }, { "nct_id": "NCT05048238", "title": "Evaluation of Tofacitinib in Prevention of Photosensitivity in Lupus", "overall_status": "COMPLETED", "study_type": "INTERVENTIONAL", "phases": [ "PHASE1" ], "conditions": [ "Cutaneous Lupus" ], "interventions": [ { "name": "Tofacitinib", "type": "DRUG" } ], "intervention_types": [ "DRUG" ], "sponsor": "National Institute of Allergy and Infectious Diseases (NIAID)", "sponsor_class": "NIH", "healthy_volunteers": false, "eligibility": { "minimum_age": "18 Years", "maximum_age": "65 Years", "sex": "ALL", "summary": "18 Years to 65 Years" }, "enrollment_count": 7, "start_date": "2022-09-30", "completion_date": "2024-02-29", "has_results": true, "last_update_posted_date": "2025-08-22", "last_synced_at": "2026-09-17T23:58:10.573Z", "location_count": 2, "location_summary": "Worcester, Massachusetts • Ann Arbor, Michigan", "locations": [ { "city": "Worcester", "state": "Massachusetts" }, { "city": "Ann Arbor", "state": "Michigan" } ], "official_url": "https://clinicaltrials.gov/study/NCT05048238" } ] }